Clinical trials: Lower Extremity Function
Total Knee Arthroplasty, Edema
The Effects of Manual Lymphatic Drainage and Kinesiotaping on Lower Extremity Edema
Significant trauma and muscular tightness often result during Total Knee Arthroplasty (TKA) surgery and thus act to restrict tissue fluid movement resulting with lower extremity edema.
- Conditions
- Total Knee Arthroplasty, Edema, Exercise
- Trial name
- NCT04164927
- Testing
- Manual Lymphatic Drainage, Kinesio Taping, Control
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Spinal Cord Injuries, Spinal Cord Diseases
Transcutaneous Auricular Vagus Nerve Stimulation in Spinal Cord Injury
This study is a single blinded prospective randomized monocentric study examining the effectiveness of transcutaneous auricular vagus nerve stimulation paired with rehabilitation and low frequency/antidromic stimulation of the…
- Conditions
- Spinal Cord Injuries, Spinal Cord Diseases, Nervous System Diseases, Trauma, Nervous System
- Trial name
- taVNS (NCT05852379)
- Testing
- active taVNS
- Volunteers
- 10 people
- Sponsor
- Possover International Medical Center AG
Lipedema, Hypermobility Syndrome (Disorder)
Investigation of Medial Longitudinal Arch and Foot Function in Patients With Lipedema
Lipedema is a chronic adipose tissue disorder that commonly leads to joint laxity, hypermobility, and functional limitations, yet its impact on foot morphology has not been systematically examined.
- Conditions
- Lipedema, Hypermobility Syndrome (Disorder), Pes Planus, Joint Hypermobility
- Trial name
- NCT07294014
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Marmara University
Hemiplegia
Effectiveness and Safety of Single Lower Limb Rehabilitation Training Robot in Stroke Patients With Hemiplegia
This trial is a multi center, randomized, controlled, excellent effect, open and loading trial design. The subjects are randomly assigned to the experimental group and the control group.
- Trial name
- NCT05360017
- Testing
- litestepper single lower limb rehabilitation training robot
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures), Hip Fractures (ICD-10 72.01-72.2)
Improving Shared DECISion-making in oldEr Hip Fracture Patients Living With Frailty
Title Improving shared decision-making in older hip fracture patients living with frailty Aim To use routinely information normally collected by the NHS, and interviews with patients, families, and healthcare professionals, to…
- Conditions
- Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures), Hip Fractures (ICD-10 72.01-72.2), Hip Fracture, Hip Fracture, Post Surgery Recovery, Muscle Resilience
- Trial name
- DECIDE-HIP (NCT07687108)
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- University of Southampton
Elevated Metabolic Cost
The Effect of Gait Training Using Virtual Reality and Real-Time Feedback on Physiological and Functional Gait Performance in Persons With a Traumatic Lower Extremity Amputation
To assess the carryover effect of an innovative new gait training program on physiological and functional gait performance in persons with a traumatic lower extremity amputation.
- Trial name
- VRVO2 (NCT01225432)
- Testing
- Gait Training
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Fracture of Hip
InterTAN: Integrated Dual Screw Design Improve Biomechanics/Function Following Fixation Surgery
The goal of this pilot, patient blinded randomized trial is to develop a mechanistic understanding of gait following fixation of unstable intertrochanteric hip fractures and return to function and pain control.
- Trial name
- NCT06024304
- Testing
- Synthes TFNA, Trigen InterTAN
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Paul E. Matuszewski
Anterior Cruciate Ligament Injuries, Cartilage Degeneration
The Mechanism for the Effects of Joint Biomechanical Properties on Medial Cartilage of Tibiofemoral Joint Degeneration
Explore The Mechanism for the Effects of Joint Biomechanical Properties on Medial Cartilage of Tibiofemoral Joint Degeneration
- Trial name
- NCT04968665
- Testing
- gait testing, functional MRI
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Muscle Physiology
Whole Body Vibration Induced Muscle Activity and Effect of the Changes in Length of Soleus Muscle and Angle of Ankle
Previous studies reported that myoelectrical activity increased during whole body vibration (WBV). The investigators hypothesized that the change in soleus muscle length does not affect the whole body vibration induced soleus…
- Trial name
- WBVIMR-SL (NCT02468011)
- Testing
- vibration
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Healthy Subject
Francis Biomechanics Study
This study aims to evaluate the effect of a range of pre-formed orthoses on function of the foot and leg to generate technical data on how the individual insoles impact gait, distribution of load and stability in a healthy…
- Trial name
- NCT03662399
- Testing
- Insoles, Standard shoe
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Ankle Fractures
Arthroscopic Assisted Open Reduction Internal Fixation Versus Open Reduction Internal Fixation in Ankle Fractures
The objective of this study is to compare the functional outcomes of patients with ankle fractures treated by Arthroscopic assisted Open Reduction Internal Fixation (AORIF) versus Open Reduction Internal Fixation (ORIF).
- Trial name
- NCT03084263
- Testing
- Arthroscopic Assisted Open Reduction Internal Fixation, Open Reduction Internal Fixation
- Where
- United States
- Sponsor
- Corewell Health West
Stroke, Weakness of Extremities as Sequela of Stroke
Effects of Exoskeleton-Assisted Gait Training on Functional Rehabilitation Outcomes in Patients With Stroke
The goal of this study is to determine the efficacy of electromechanical exoskeleton-assisted gait training on rehabilitation functional outcomes in patients with stroke undergoing therapy in an in-patient rehabilitation facility.
- Trial name
- NCT03980457
- Testing
- Indego Exoskeleton, Standard Rehabilitation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Oklahoma
Anterior Cruciate Ligament Injury
Arthroscopic Anterior Cruciate Ligament Reconstruction by Hamstring Graft With and Without Platelet-Rich Plasma
No local data exists regarding the outcomes of anterior cruciate ligament reconstruction by hamstring graft with and without platelet-rich plasma.
- Trial name
- NCT07269522
- Testing
- ACL reconstruction by hamstring graft with PRP, ACL reconstruction by hamstring graft
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Muhammad Aamir Latif
Stroke, Walking Impairment
Investigating the Mechanisms of Welwalk Robot in Restoring Motor Function of the Lower Extremities in Stroke Patients
Current evidence and clinical applications of robotic gait training devices for motor function recovery post-stroke are increasingly available.
- Trial name
- NCT07057700
- Testing
- welwalk training, physical therapy
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Ruijin Hospital
Primary Lymphedema, Aerobic Exercise
The Effects of Aerobic Exercise in Patients With Primary Lower Extremity Lymphedema
Our aim in this study is to evaluate the effects of lymphedema on exercise capacity, body composition, functional level and quality of life in lymphedema patients with primary lower extremity involvement.
- Trial name
- NCT06327412
- Testing
- Aerobic exercise on the treadmill, Walking between 12-13 RPE (The Borg Rating of Perceived Exertion) according to the Modified Borg Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Kayseri City Hospital
Stroke
Effects of Task-Oriented Training With and Without Rhythmic Auditory Stimulation in Post-Stroke Patients
Stroke is one of the leading causes of long-term disability worldwide. Among survivors, limitations in lower limb motor function, balance, and proprioception significantly affect their independence and quality of life.
- Trial name
- NCT07724730
- Testing
- Task-Oriented Training + Rhythmic Auditory Stimulation, Task-Oriented Training Only
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Patella, Joint Instability
Development of a Test Battery for Measurement of Knee Function in Patients With Patellar Instability
About six months after patella stabilizing surgery postoperative restrictions are commonly lifted and patients may consider whether a return to activity/sports is feasible.
- Conditions
- Patella, Joint Instability, Patellofemoral Joint Dislocation
- Trial name
- NCT05119088
- Testing
- Return to Sport testbattery
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Haraldsplass Deaconess Hospital
Lower Limb Amputation Above Knee (Injury)
New Microprocessor-Controlled Prosthetic Knee Evaluation
The target of this clinical investigation is to compare the achievement of personal functional goals using a new MPK and current MPK.
- Trial name
- NCT06017024
- Testing
- microprocessor-controlled knee (MPK) assessment
- Where
- 5 sites in France
- Volunteers
- 18 people
- Sponsor
- Proteor Group
Lower Limb Amputation Knee, Lower Limb Amputation Above Knee (Injury)
Enhancing Abilities in Amputees and Patients With Peripheral Neuropathy Through Restoration of Sensory Feedback
Many amputees suffer from Phantom Limb Pain (PLP), a condition where painful perceptions arise from the missing limb. Leg amputees wear prostheses that do not provide any sensory feedback, apart from the stump-socket interaction.
- Conditions
- Lower Limb Amputation Knee, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury), Diabetic Peripheral Neuropathy
- Trial name
- NCT04217005
- Testing
- Sensory Feedback
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- ETH Zurich
Flexible Flatfoot
Clinical Trial of the Effect of Functional Orthoses in Children With Flat Feet
The purpose of this study is to investigate the efficay of functional plantar orthoses on flatfoot in children.
- Trial name
- NCT02633566
- Testing
- Plantar orthoses
- Volunteers
- 61 people
- Sponsor
- Fresno, Raquel Lopez, M.D.