Clinical trials: Lower Extremity Motor Dysfunction
Post Stroke, Mobility
Effect of Modified Constraint-induced Movement Therapy Combined With Virtual Reality on Mobility in Post-stroke Patients: A Randomized Control Trial
This study investigates the effectiveness of combining m-CIMT and VR to improve mobility in post-stroke patients. A non-blinded randomized controlled trial will be conducted with 32 participants divided equally into experimental…
- Conditions
- Post Stroke, Mobility, Balance
- Trial name
- NCT06975904
- Testing
- m-CIMT with VR exer-games by Kinect Xbox 360, m-CIMT with Task-Specific Functional Training
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Foundation University Islamabad
Stroke
Efficacy of Temporal Interference-based Deep Brain Stimulation Combined With Conventional Rehabilitation Training for Lower Limb Motor Dysfunction After Stroke
Stroke, as one of the most disabling neurological diseases worldwide, causes significant functional impairments in the lower limbs, severely affecting the quality of life of patients.
- Trial name
- NCT07833423
- Testing
- Transcranial Temporal Interference (TI) Stimulation, routine rehabilitation
- Volunteers
- 60 people
- Sponsor
- The Third People's Hospital of Huizhou
Hip Fractures, Mild Cognitive Impairment
Reducing Fall Risk Post Hip Fracture in Mild Cognitive Impairment
Hip fracture is recognized as one of the most serious consequences of osteoporosis, less than half regain pre-fracture independence. 95% of all hip fractures in older adults are due to falls.
- Trial name
- NCT04748354
- Testing
- Otago Exercise Program, Usual Care
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Stroke, Gait Disorders, Neurologic
ZEPU AI9 Exoskeleton Rehabilitation Robot
The goal of this clinical trial is to learn whether the ZEPU AI9 lower limb exoskeleton robot is feasible, safe, and effective for people with walking difficulty caused by stroke, incomplete spinal cord injury, or orthopedic…
- Conditions
- Stroke, Gait Disorders, Neurologic, Spinal Cord Injuries, Incomplete, Postoperative Complication
- Trial name
- NCT07750808
- Testing
- ZEPU-AI9 Lower Limb Exoskeleton Gait Training, Standard-of-Care Rehabilitation
- Where
- Bangladesh
- Volunteers
- 36 people
- Sponsor
- Bangladesh Medical University
Lower Extremity Motor Dysfunction, Spinal Cord Injury
Evaluation of the Effectiveness and Safety of AI-Robotics
Evaluation of the effectiveness and safety of the lower extremity exoskeleton rehabilitation training robot
- Trial name
- ART (NCT03452059)
- Testing
- AiLegs, AiWalker and HKAFO
- Where
- China
- Volunteers
- 40 people
- Sponsor
- AI-Robotics Technology Co., Ltd
Stroke Rehabilitation
Substantiation and Standardization of the Multimodal Cognitive-motor Rehabilitation System for Afterstroke Patients
The aim of the study is to develop and scientifically substantiate a standardized system of multimodal cognitive-motor rehabilitation and its differentiated application in patients with cerebral stroke, according to verified…
- Trial name
- NCT05944666
- Testing
- Multimodal technology (MT), Conventional rehabilitation
- Where
- Russia
- Volunteers
- 405 people
- Sponsor
- Moscow Scientific and Practical Center of Medical Rehabilitation, Restorative and Sports Medicine
Stroke Patients With Hemiplegia or Hemiparesis in the Subacute Stage
The Effect of Combined Transcranial Pulse Current Stimulation (tPCS) and Transcutaneous Electrical Nerve Stimulation (TENS) on Lower Limb Motor Function in Subacute to Chronic Stroke Patients With Hemiplegia (COMPENSATOR-Stroke)
The goal of this study is to evaluate the effects of high frequency tPCS + TENS compared to Sham device stimulation + TENS (Control) in lower limb motor function recovery in stroke patients with hemiplegia or hemiparesis in the…
- Trial name
- COMPENSATOR (NCT06999876)
- Testing
- The AscenZ-VIII Stimulator (Investigational Medical Device)
- Where
- 2 sites in Singapore
- Volunteers
- 90 people
- Sponsor
- National University Health System, Singapore
Stroke, Walking Impairment
Investigating the Mechanisms of Welwalk Robot in Restoring Motor Function of the Lower Extremities in Stroke Patients
Current evidence and clinical applications of robotic gait training devices for motor function recovery post-stroke are increasingly available.
- Trial name
- NCT07057700
- Testing
- welwalk training, physical therapy
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Ruijin Hospital
Hemiplegia, Lower Extremity Dysfunction
Lower Extremity Pressure Splints in HP
Hemiplegia (weakness or paralysis on one side of the body) often impacts the lower extremities, making it challenging for patients to walk or move their legs effectively.
- Conditions
- Hemiplegia, Lower Extremity Dysfunction, Stroke Rehabilitation
- Trial name
- NCT06965894
- Testing
- Johnston Pressure Splint, Rehabilitation Program
- Where
- Lebanon
- Volunteers
- 30 people
- Sponsor
- Istinye University
Stroke, Incomplete Spinal Cord Injury (SCI)
ZEPU-2000 Limb Rehabilitation Trainer Study (ZEPU2000RCT)
The goal of this clinical trial is to learn whether the ZEPU-2000A, ZEPU-2000D and ZEPU-2000E robotic rehabilitation trainers help people with weakness or movement problems in their arms and legs.
- Conditions
- Stroke, Incomplete Spinal Cord Injury (SCI), Traumatic Brain Injury, Upper Extremity Motor Dysfunction
- Trial name
- NCT07749612
- Testing
- ZEPU-2000A, ZEPU-2000D, ZEPU-2000E
- Where
- Bangladesh
- Volunteers
- 36 people
- Sponsor
- Bangladesh Medical University
Cardiovascular Disease Risk Reduction, Diabetes
Interval Training and Electromagnetic Therapy on Cardiovascular Disease Risk in Diabetic Elderly
Aims: To evaluate the combined effect of moderate intensity interval training and low frequency pulsed electromagnetic field therapy on cardiovascular disease risk and lower extremity functioning in the elderly with type 2…
- Conditions
- Cardiovascular Disease Risk Reduction, Diabetes, Lower Extremity Dysfunction
- Trial name
- NCT06974435
- Testing
- Interval training and electromagnetic therapy, Interval exercise training, Electromagnetic therapy
- Where
- Saudi Arabia
- Volunteers
- 100 people
- Sponsor
- Umm Al-Qura University
Adrenomyeloneuropathy Without Cerebral Involvement
Epidural Spinal Cord Stimulation for Lower-limb Impairment in Adrenomyeloneuropathy
Adrenal spinal neuropathy (AMN) is a rare X-linked genetic disease caused by mutations in the ABCD1 gene, and belongs to a special type of adrenal leukodystrophy.
- Trial name
- EPIC-AMN (NCT06796920)
- Testing
- Spinal cord stimulation
- Where
- 4 sites in China
- Volunteers
- 10 people
- Sponsor
- Third Military Medical University
Motor Deficits, Lumbar Discectomy
Investigation of Preoperative Factors Influencing the Outcome of Motor Deficits in Patients Undergoing Lumbar Microdiskectomy
Lumbar disc herniations may result in lower limb weakness. In such cases, there is a strong indication for surgical intervention through microdiscectomy.
- Conditions
- Motor Deficits, Lumbar Discectomy, Muscle Weakness, Paresis
- Trial name
- NCT07413302
- Where
- 3 sites in Greece
- Volunteers
- 40 people
- Sponsor
- Aristotle University Of Thessaloniki
Stroke, Spinal Cord Injuries
ZEPU-AI Series Limb Feedback Robot Training Study (ZEPUAISRCT)
The goal of this clinical trial is to learn whether robotic rehabilitation devices (ZEPU-AI2, AI4, AI6 Plus, and AI7A) are feasible, safe, and effective for adults with upper or lower limb motor problems.
- Conditions
- Stroke, Spinal Cord Injuries, Brain Injuries, Traumatic, Movement Disorder, Upper Extremity
- Trial name
- NCT07749625
- Testing
- ZEPU-AI2, ZEPU-AI4, ZEPU-AI6 Plus
- Where
- Bangladesh
- Volunteers
- 36 people
- Sponsor
- Bangladesh Medical University