Clinical trials: Lower Extremity Pain
Knee Injuries, Pain Syndrome
The Effect of Kinesio Taping® on Motor Control in Patients With Patellofemoral Pain Syndrome
Background: Recently, several professionals are using the Kinesio Taping® in the treatment of pathologies related to the knee, aiming to improve the motor control, increase the response of muscle activation and promoting better…
- Trial name
- NCT03117205
- Testing
- Application of Kinesio Taping®
- Volunteers
- 40 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures), Postoperative Pain
FICB for Hip Fracture Pain in Elderly
Hip fracture is a common injury in elderly patients, often requiring surgical treatment. However, these patients frequently experience severe postoperative pain, which can delay mobility and recovery, and increase the risk of…
- Conditions
- Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures), Postoperative Pain, QoR-15, Fascia Iliaca Block
- Trial name
- FICB-PREP (NCT07762846)
- Testing
- Ultrasound-Guided Fascia Iliaca Compartment Block
- Where
- China
- Volunteers
- 144 people
- Sponsor
- RenJi Hospital
Protruded Disk
CLARIX™ 100 & CLARIX CORD 1K for Discectomy Patients
The purpose of the study is to evaluate the efficacy of CLARIX™ 100 and CLARIX™ CORD 1K as a tissue barrier when used as an annular patch in discectomy patients with low back \& leg pain when compared to traditional discectomy…
- Trial name
- NCT03113786
- Testing
- CLARIX™100, CLARIX CORD 1K
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Amniox Medical, Inc.
Femoral Neck Fractures, Intertrochanteric Fractures
Opioid-Free Pain Treatment in Trauma Patients
Analgesic drug study that will compare pain outcomes of opioid analgesia and opioid-free analgesia in post-operative orthopedic patients.
- Conditions
- Femoral Neck Fractures, Intertrochanteric Fractures, Femoral Shaft Fracture, Distal Femur Fracture
- Trial name
- NCT06078371
- Testing
- Opioid-free pain treatment
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Kansas Medical Center
Ankle Sprain
HKT-500 in Adult Patients With Ankle Sprain
The objective of this study is to demonstrate the multiple-dose efficacy and safety of HKT-500 for the treatment of ankle sprain.
- Trial name
- NCT00680784
- Testing
- HKT-500 Ketoprofen Topical Patch
- Where
- 30 sites in United States
- Volunteers
- 260 people
- Sponsor
- Hisamitsu Pharmaceutical Co., Inc.
Orthopedic Procedures, Pain, Postoperative
Risk Model for Severe Rebound Pain After Lower Limb Orthopedic Surgery Involving Single-Shot Sciatic Nerve Blocks
Rebound pain is a well-recognized phenomenon after the effects of a nerve block wear off. Severe rebound pain can happen after outpatient surgery, with patients often needing to come back to the hospital or use other health care…
- Conditions
- Orthopedic Procedures, Pain, Postoperative, Surgery, Nerve Block
- Trial name
- NCT05018104
- Testing
- This is not an interventional study
- Where
- Canada
- Volunteers
- 1,270 people
- Sponsor
- University of British Columbia
Femoral Neck Fracture
Trochanteric Bursa Repair and Lateral Hip Pain After Hemiarthroplasty for Femoral Neck Fracture
This study aims to determine whether repairing the trochanteric bursa during hip hemiarthroplasty reduces lateral hip pain after surgery in patients aged 65 years and older with femoral neck fractures.
- Trial name
- NCT07878143
- Testing
- Trochanteric Bursa Repair, Trochanteric Bursa Left Unrepaired
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Osman Sarıyar
Critical Limb Ischemia
Continuous Sciatic Block Nerve in the Management of Vascular Pain in Critical Ischemia of Lower Limbs Patients
Critical limb ischemia (CLI) is associated with severe pain that is a therapeutic challenge whit therapeutic limits for the use of conventional analgesics medications.
- Trial name
- NCT04278014
- Testing
- ultrasound-guided continuous sciatic block with longitudinal approach
- Where
- 2 sites in Colombia
- Volunteers
- 13 people
- Sponsor
- Universidad de Antioquia
Prolapsed Intervertebral Disc
Effects of Lumbar Traction on the Straight Leg Raise Test and Pain
Disc prolapse causes impairment of function by nerve root compression compelling the patient to seek medical advice for low backache.
- Trial name
- NCT04728685
- Testing
- Mechanical Traction
- Where
- Saudi Arabia
- Volunteers
- 45 people
- Sponsor
- King Saud University
Running-related Injuries, Medial Tibial Stress Syndrome
Machine Learning-Based Risk Identification and Precision Exercise for Common Running Injuries
This study aims to identify biomechanical risk factors associated with common running-related injuries in recreational runners using machine learning analysis.
- Conditions
- Running-related Injuries, Medial Tibial Stress Syndrome, Patellofemoral Pain, PFP, Chronic Achilles Tendinopathy
- Trial name
- NCT07689916
- Testing
- Multidimensional Precision Intervention, Precision Exercise Intervention
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Zeyi Zhang
Hip Fractures, Post Operative Pain
Dose and Concentration Relationship for PENG Block in Hip Surgery
A number of peripheral nerve blocks are routinely performed in patients who will undergo orthopedic hip surgery for pain relief.
- Trial name
- NCT05400148
- Testing
- Bupivacaine Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Diabetic Neuropathy Peripheral
Dual Field PEMF Therapy in Lower Extremity Painful Diabetic Distal Symmetric Peripheral Neuropathy
Part A of this trial is a multi-center, prospective, double-blinded, sham-controlled, randomized clinical trial. Part A will evaluate PEMF treatment compared to sham treatment in patients with painful diabetic distal symmetric…
- Trial name
- RELIEF (NCT03455543)
- Testing
- Active Provant Therapy System
- Where
- 18 sites in United States
- Volunteers
- 182 people
- Sponsor
- Regenesis Biomedical, Inc.
Ankle Fractures
Local Multimodal Injection Versus Regional Anesthesia in Controlling Pain for Treating Rotational Ankle Fractures
The investigators plan to evaluate the efficacy in reducing post-operative pain between local multimodal analgesia as compared to regional anesthesia in rotational ankle fractures.
- Trial name
- NCT05019638
- Testing
- Regional anesthesia group, Local multimodal analgesia group
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Pain, Chronic, Pain, Back
Ultra-high Frequency (500 KHz) Spinal Cord Stimulation for Treatment of Chronic Back Pain or Lower Limb Pain
This study is a prospective, single-arm, open label, single center to confirm the effectiveness and safety of an ultra-high frequency (500 KHz) spinal cord stimulation in patients with chronic back pain or lower limb pain.
- Conditions
- Pain, Chronic, Pain, Back, Pain, Radiating
- Trial name
- NCT03543085
- Testing
- GiMer Medical MN 1000 External Stimulator
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- GiMer Medical
Lower Extremity Pain of a Mechanical Origin
Custom Molded Foot Orthoses Effect on Foot Kinematics and Lower Extremity Electromyography During Walking and Running.
The purpose of this study was to determine the effectiveness of two types of in-shoe custom made orthotics in altering the motion of the foot and muscle activity of select muscles of the lower leg in individuals experiencing…
- Trial name
- SOLE (NCT02143947)
- Testing
- Maximal Arch Subtalar Stabilization, Full Contact Orthosis
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Quinnipiac University
Varicose Veins of Lower Limb, Chronic Venous Insufficiency, CVI
Efficacy and Safety of Endovenous Ablation for Relief of Knee Pain in Elderly Patients With Lower Extremity Varicose Veins: A Prospective Observational Study
Lower extremity varicose veins (LEVV) are common among elderly patients and can cause leg heaviness, pain, and swelling. In some older adults, venous congestion may contribute to knee or peri-knee pain, which is often…
- Conditions
- Varicose Veins of Lower Limb, Chronic Venous Insufficiency, CVI, Knee Pain, Knee Osteoarthritis
- Trial name
- EVA-Knee-Elder (NCT07239284)
- Testing
- Endovenous Ablation for Varicose Veins
- Volunteers
- 50 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Anterior Cruciate Ligament Injuries
Perturbation Training vs Functional Activities on Pain, ROM, Balance, and Function Post-ACL
Anterior cruciate ligament (ACL) injuries are among the most common and functionally disabling knee injuries, particularly in physically active individuals.
- Trial name
- NCT07642752
- Testing
- Perturbation Training Group, Task-Oriented Functional Activities Group, Control Group (Standard Rehabilitation Protocol)
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Y-balance, Patellofemoral Pain Syndrome
Assessing Lower Extremity Dynamic Stability in Middle-Aged and Elderly Patients With Patellofemoral Pain Using the Y-Balance Test
Background: Patellofemoral pain syndrome (PFPS) is a common functional disorder of knee joint. Its etiology involves biomechanical abnormalities and dynamic stability defects.
- Trial name
- NCT07068984
- Testing
- Differences between lower limb balances were assessed by the Y-Balance test
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking University Third Hospital
Hip Fractures, Pain, Acute
Pericapsular Nerve Group Block for Hip Fractures
This will be a feasibility study to see if it feasible to perform the Pericapsular Nerve Group Block for hip fractures in the Emergency Department.
- Trial name
- NCT04882384
- Testing
- Pericapsular Nerve Group Block
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jacobi Medical Center
Pain Management, Perioperative Analgesia
From Battlefield to Recovery: Continuous Regional Anaesthesia for War-Related Lower Limb Trauma
To compare the effectiveness of continuous regional anaesthesia with standard pain management strategies for the treatment of acute pain in patients with war-related lower limb trauma.
- Conditions
- Pain Management, Perioperative Analgesia, War-Related Injuries
- Trial name
- CRA-WAR-LIMB S (NCT07474506)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)