Clinical trials: Lower Extremity Pain
Peripheral Arterial Disease, Atherosclerotic Lesion
Study of the R3 Vascular Drug-Eluting Bioresorbable Scaffold in Treating Below the Knee Arterial Disease
This first-in-human clinical feasibility study will evaluate the safety and performance of the R3 Vascular MAGNITUDE® Bioresorbable Drug-Eluting Scaffold and Delivery System in patients undergoing treatment for peripheral…
- Conditions
- Peripheral Arterial Disease, Atherosclerotic Lesion, Lower Extremity Ischemia, Lower Extremity Claudication
- Trial name
- RESOLV I (NCT04912323)
- Testing
- Percutaneous Implantation of the MAGNITUDE® Bioresorbable Arterial Scaffold
- Where
- 7 sites in Austria, Canada and 1 more
- Volunteers
- 30 people
- Sponsor
- R3 Vascular Inc.
Pain, Postoperative
Norspan Versus Oxycontin as Postoperative Painkiller to Proximal Extracapsular Fractures of the Femur
Effective treatment of pain after hip fractures is very important but difficult. It is often an old patient who has many adverse effects with the use of morphine.
- Trial name
- NCT00964808
- Testing
- Buprenorphine, Oxycodone
- Where
- Denmark
- Volunteers
- 76 people
- Sponsor
- Vejle Hospital
Femur Fracture
Evaluation of the Postoperative Analgesic Efficacy of the Quadroiliac Plane (QIP) Block in Femur Fracture Surgery
The goal of this clinical trial is to learn whether the Quadroiliac Plane (QIP) block helps reduce postoperative opioid use in adults undergoing femur fracture surgery.
- Trial name
- NCT07009782
- Testing
- QIP block
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Back Pain Lower Back Chronic
Caudal Epidural Injection of Dextrose For Low Back Pain
Objective: The purposes of the study are to 1. Explore the immediate and short term (to 48 hour) analgesic potential of epidural D5W in comparison to normal saline. 2.
- Trial name
- NCT01547364
- Testing
- Saline, Dextrose
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Smigel, Liza, M.D.
Low Back Pain
Multiplanar Lumbopelvic Control in Patients With Low Back Pain
The purpose of this study was to investigate whether combined assessment of lumbopelvic control during sagittal and frontal plane motion (using two common clinical observational assessments) discriminates between people with and…
- Trial name
- NCT02089321
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Regis University
Venous Stasis Ulcers
The Effects of Pulsed Elelectro-Magnetic Fields ("PEMF") in the Treatment of Venous Stasis Leg Ulcers
The purpose of this study is to determine the clinical effectiveness of a low-power PEMF device, a medium-power PEMF device and a high-power PEMF device as compared to a sham device to treat leg ulcers resulting from venous…
- Trial name
- VSLU (NCT03416049)
- Testing
- PEMF therapy with a high-power PEMF device, PEMF therapy with a medium PEMF power device, PEMF therapy with a low-power PEMF device
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- PEMF Systems, Inc.
Back Pain, Headache
Influence of Dalcroze Eurhythmics on Pains in Older Women
In this study, we attempted to answer the question of whether participation in a 12-week rhythmic exercise program using the Dalcroze method affects the level of intensity of pain experienced by women over the age of 65.
- Conditions
- Back Pain, Headache, Leg Pain
- Trial name
- NCT06264102
- Testing
- Physical exercise program
- Where
- Poland
- Volunteers
- 61 people
- Sponsor
- Poznan University of Physical Education
Osteoarthritis, Knee, Pain
Assessment of the Effect of Spa Treatment on the Functional Severity of Arthrosis
Assessment of the effect of spa treatment on the functional severity of arthrosis. Official title: Evolution of clinical state of patients with rheumatic disease on lower limbs or rachis, 6 months after spa treatment.
- Trial name
- VALS (NCT03336099)
- Testing
- Spa Treatment
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Le Syndicat Intercommunal pour le Thermalisme et l'Environnement
Back Pain, Back Pain With Radiation
Sub-Sensory Intraspinal Neurostimulation Therapy
To explore the optimal stimulation parameters and locations for sub-perception programming in patients with previously implanted spinal cord stimulation systems for the treatment of chronic back and/or leg pain.
- Conditions
- Back Pain, Back Pain With Radiation, Pain in Leg, Unspecified
- Trial name
- NCT01976598
- Testing
- Sub-Sensory Stimulation
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Algos Clinical Development Thomas L. Yearwood, MD, PhD
Injury of Anterior Cruciate Ligament
Opioid Use in Single Shot Nerve Block vs Continuous Peripheral Nerve Infusion in Anterior Cruciate Ligament (ACL) Repair
Anterior cruciate ligament repair using hamstring autograft in children is a painful orthopedic procedure. The current practice to provide analgesia for this procedure include femoral continuous perineural infusion and femoral…
- Trial name
- NCT02075411
- Testing
- bupivacaine, continuous perineural infusion catheter
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Children's Hospital of Philadelphia
Hip Fractures, Regional Anesthesia
Comparison of PENG Block and FICB in Hip Fracture Patients
Fascia iliaca compartment block (FICB) has been considered the block of choice for patients with hip fracture. However, pericapsular nerve group (PENG) block, one of the relatively newly-developed blocks, could be also used for…
- Trial name
- NCT04677348
- Testing
- Pericapsular nerve group (PENG) block, Fascia iliaca compartment block (FICB)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Asan Medical Center
Patellofemoral Pain Syndrome, ACL Tear
Kinematic Assessment of Human Peripheral Joints by Dynamic CT
Aim of the research project: The entire research project aims to investigate human peripheral joints (knee, foot \& ankle, elbow, wrist \& hand) by dynamic 4D radiographic imaging acquisition during real-time motion.
- Trial name
- Karma-4D (NCT04732585)
- Testing
- Physiotherapy or Surgery
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Radiculopathy, Lower Extremity Radicular Pain
Somatosensory Profiling in Radicular Pain Patients And it's Correlation With Treatment Outcome
The investigators hypothesize that there may exist different quantitative sensory profiles between radicular pain patients who respond and those who do not respond to the standard therapy of epidural steroid injections (ESI).
- Trial name
- NCT02130258
- Testing
- Quantitative Sensory Testing (QST), Epidural Steroid Injection (ESI)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Massachusetts General Hospital
Medial Tibial Stress Syndrome
Effects of Therapeutic Ultrasound Versus Shockwave Therapy in Medial Tibial Stress Syndrome in Recreational Runners
This project was a Randomized control trial conducted to check the effects of therapeutic ultrasound versus shockwave therapy on pain , range of motion and function in recreational runners with medial tibial stress syndrome so…
- Trial name
- NCT05392036
- Testing
- baseline physical therapy treatment along with shockwave therapy, baseline physical therapy treatment along with therapeutic ultrasound
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
ACL Injury
Does Bone Grafting at the Time of Bone-Patellar Tendon-Bone ACL Reconstruction Reduce the Incidence of Post-operative Anterior Knee Pain: A Randomized Controlled Clinical Study
It is estimated that 48 out of 10,000 people, in the United States, will tear their anterior cruciate ligament (ACL) annually and undergo ACL reconstruction (ACLR).
- Trial name
- NCT04958733
- Testing
- Autologous bone grafting, Absence of autologous bone grafting
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Hartford Hospital
Patellofemoral Pain Syndrome
Relationship Between Knee Pain And Proprioception During Single Leg Squat In Patellofemoral Pain Syndrome
This study will be conducted to investigate the relationship between knee joint pain intensity and joint position sense accuracy in patients with patellofemoral pain syndrome (PFPS) in a single-leg squat position.
- Trial name
- PPS (NCT07642011)
- Testing
- patellofemoral pain syndrome patients
- Volunteers
- 82 people
- Sponsor
- Cairo University
Fractures, Hip, Femoral Neck Fractures
Preoperative Use of Peripheral Nerve Blocks in Elderly Patients With Hip Fractures
The goal of this clinical trial is to explore the effects of different peripheral nerve blocks in older adults with hip fractures. It will also explore the safety of preoperative administration of peripheral nerve blocks.
- Conditions
- Fractures, Hip, Femoral Neck Fractures, Intertrochanteric Fractures, Subtrochanteric Fractures
- Trial name
- NCT07130006
- Testing
- PENG and LFCN peripheral nerve blocks with spinal anesthesia, FN and LFCN peripheral nerve blocks with spinal anesthesia, FIC peripheral nerve block with spinal anesthesia
- Where
- Croatia
- Volunteers
- 256 people
- Sponsor
- University Hospital of Split
Spinal Cord Stimulation
New Markers to Assess the Efficacity of Spinal Cord Stimulation for the Treatment of Chronic Lower Limb Pain (MOTIVE)
By combining the usual care of patients eligible for spinal cord stimulation (SME) with measurements of the HRV index (Heart Rate Variability), objective measurements of activity (number of steps, quality of sleep) and…
- Trial name
- NCT04785001
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Pain, Knee Osteoarthritis
Effects of a Machine Learning-based Lower Limb Exercise Training System for Knee Pain
The goal of the study is to confirm the idea of AI-powered Technological Surrogate Physiotherapist (TSP), by demonstrating its effectiveness and value as a new technology-based contribution to OA healthcare.
- Trial name
- NCT05173064
- Testing
- The AI-powered Technological Surrogate Physiotherapist, Face-to-face physiotherapist-supervised exercise program
- Where
- Hong Kong
- Volunteers
- 176 people
- Sponsor
- The University of Hong Kong
Venous Leg Ulcer, Pain
The Effect of Different Types of Music on Pain and Anxiety During Wound Care Procedures in Patients With Venous Ulcers
Objective: To evaluate the effects of different types of music (instrumental Turkish music and Western music without lyrics) played during wound care on pain, anxiety, and patient satisfaction among individuals with venous…
- Conditions
- Venous Leg Ulcer, Pain, Anxiety
- Trial name
- MUPAW (NCT07287254)
- Testing
- Turkish Music Intervention, Western Music Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people
- Sponsor
- Izmir Katip Celebi University