Clinical trials: Lower Extremity Pain
Pegfilgrastim-induced Back and Leg Pain
Evaluation of Loratadine for Prevention of Pegfilgrastim-Induced Pain
The purpose of this study is to determine the incidence of pegfilgrastim-induced back and leg pain and to determine whether the antihistamine loratadine can prevent pegfilgrastim-induced back and leg pain.
- Trial name
- NCT01311336
- Testing
- Loratadine
- Where
- 7 sites in United States
- Volunteers
- 55 people
- Sponsor
- University of Vermont
Y-balance, Patellofemoral Pain Syndrome
Assessing Lower Extremity Dynamic Stability in Middle-Aged and Elderly Patients With Patellofemoral Pain Using the Y-Balance Test
Background: Patellofemoral pain syndrome (PFPS) is a common functional disorder of knee joint. Its etiology involves biomechanical abnormalities and dynamic stability defects.
- Trial name
- NCT07068984
- Testing
- Differences between lower limb balances were assessed by the Y-Balance test
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking University Third Hospital
Lower Limb Amputation
Phantom Exercise for Lower Limb Amputees
In this research, the aim is to find out the effects of phantom exercises in terms of pain, mobility and quality of life among lower-limb amputees having phantom limb pain.
- Trial name
- NCT04285138
- Testing
- phantom limb exercise, conventional treatment
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Phantom Limb Pain, Phantom Pain
Study of Lower-limb Phantom Pain Syndrome Using Peripheral Nerve and Spinal Cord Stimulation
Brief Summary: The purpose of this study is to evaluate the effectiveness of neuromodulation for relief of phantom limb pain (PLP) using peripheral nerve (PNS) and spinal cord (SCS) stimulation with implantable electrodes.
- Conditions
- Phantom Limb Pain, Phantom Pain, Amputation, Lower Limb Amputation
- Trial name
- NCT05807607
- Testing
- Implantation of PNS electrodes during surgery, mapping to select sites with the best effect and daily modulation., SCS electrode implantation at surgery, mapping to select sites with the best effect and pain modulation, Change according to the scale of the PainDetect questionnaire
- Where
- Russia
- Volunteers
- 10 people
- Sponsor
- Artur Biktimirov
Chronic Pain, Back Pain
ECAP-controlled, Closed-loop Stimulation to Treat Chronic Trunk and/or Limb Pain (ECAP)
The purpose of this study is to evaluate neurophysiological measures and clinical outcomes of the Evoke System to treat trunk and/or limb pain in a real-world population.
- Conditions
- Chronic Pain, Back Pain, Pain
- Trial name
- ECAP (NCT04319887)
- Testing
- Evoke Spinal Cord Stimulation (SCS) System
- Where
- 22 sites in United States
- Volunteers
- 300 people
- Sponsor
- Saluda Medical Pty Ltd
Chronic Pain
Trans-foraminal Lumbar Epidural Injection of Dexmedetomidine Against Magnesium Sulfate When Combined With Dexamethasone in Uni-lateral Lower Limb Radicular Pain. Multi-centeric Comparative Study
Transforaminal injection of chronic radicular lower limb injection by either dexmedetomdine or magnesuim sulfate
- Trial name
- NCT05271721
- Testing
- epidural transforaminal injection of magnesuim sulfate, epidural transforaminal injection of dexmedtemodine, transforaminal epidural injection of dexamethasone
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Minia University
Electromyography, Knee Injuries
Vastus Medialis Activation During McMurray's Test
This study will use electromyography to evaluate activation patterns of the vastus medialis and vastus lateralis muscles during the McMurray's knee examination test in different knee positions.
- Conditions
- Electromyography, Knee Injuries, Knee Pain Chronic
- Trial name
- NCT05965804
- Testing
- McMurray knee examination test
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ahram Canadian University
Ankle Fracture
NSAIDS Versus Opioids in Acute SER II Ankle Fractures
This study is being conducted to evaluate whether NSAIDS are more or less effective in bone healing than opioids in acute fracture pain.
- Trial name
- NCT02373254
- Testing
- Ibuprofen, Acetaminophen/hydrocodone
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of California, Davis
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Dynamic Q Angle and Core Endurance in Adolescent Athletes With Patellofemoral Pain Syndrome
This observational, cross-sectional study aimed to compare dynamic Q-angle, trunk/core endurance, and lower-extremity flexibility between elite adolescent female and male sprinters with and without patellofemoral pain syndrome…
- Trial name
- PFPS-QCORE (NCT07328750)
- Testing
- Patellofemoral Pain Syndrome Status
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Pain, Postoperative, Femur Fracture
Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur Fractures
The purpose of this study is to determine the efficacy and safety of a peri-incisional multimodal injection for post-operative pain control following operative management of femur fractures.
- Trial name
- NCT02793947
- Testing
- Ropivacaine, Epinephrine, Morphine
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Iowa
Tenopathy; Lower Limb
Efficacy of Manual Therapy Combined With an Exercise Programme VS Combined Electrotherapy on Football Players With Adductor Tendinopathy
Background: Groin pain associated with adductor tendinopathy is the second cause of muscle pathology in a football player (20%), so a good treatment taking into account both internal and external factors that may influence the…
- Trial name
- NCT04935398
- Testing
- Physiotherapy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Católica de Ávila
Traumatic Amputation of Lower Extremity, Phantom Limb Pain
Spinal Root and Spinal Cord Stimulation for Restoration of Function in Lower-Limb Amputees
The goals of this study are to provide sensory information to amputees and reduce phantom limb pain via electrical stimulation of the lumbar spinal cord and spinal nerves.
- Trial name
- SCS-LL (NCT03027947)
- Testing
- Spinal cord stimulator
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Pittsburgh
Wounds Injuries, Anesthesia, Local
Single-centre Study to Investigate Safety and Efficacy of Tri-Solfen in Wound Debridement
This is a Phase IIa open, randomised, single and parallel group, therapy controlled, single centre study, which has been divided into 3 sequential phases, which are designed to study respectively, (a) the time taken to achieve…
- Trial name
- NCT03865147
- Testing
- Tri-Solfen Gel (Lidocaine HCl, Bupivacaine HCl, Adrenaline Acid Tartrate /Cetrimide), EMLA cream, Post Operative Analgesia (Paracetamol, Ibuprofen)
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Medical Ethics UK Ltd
Chronic Pain, Low Back Pain
A Prospective, Multi-site, Randomized, Sham-Controlled, Double-Blind Trial With One-Way Crossover Designed to Assess the Effectiveness and Safety of the Gimer NeuroBlock SCS Trialing System for the Treatment of Chronic Back Pain and/or Lower Limb Pain
This study is a prospective, multi-site, randomized, shamcontrolled, double-blind trial with one-way crossover designed to assess the effectiveness and safety of the Gimer NeuroBlock SCS Trialing System for the treatment of…
- Conditions
- Chronic Pain, Low Back Pain, Lower Limb Pain
- Trial name
- NCT04693650
- Testing
- NeuroBlock UHF stimulation
- Where
- 4 sites in Taiwan
- Volunteers
- 22 people
- Sponsor
- GiMer Medical
Pelvic Girdle Pain
Predictive Value of the Active Straight Leg Raise on the Efficacy of a SJB in Posterior PGP During Pregnancy
During pregnancy, women often experience musculoskeletal pain, specifically in their low back and/or pelvic girdle. Pelvic girdle pain (PGP) is defined as pain between the posterior iliac crest and gluteal fold, particularly in…
- Trial name
- NCT03518840
- Testing
- SIJ Belt
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Loyola University
Phantom Limb Pain
Massage Therapy for Phantom Limb Pain: Feasibility and Pilot Study
Massage therapy is a treatment self-reported by those with phantom limb pain (PLP) as moderately to extremely effective, but no research to date has been specifically designed to examine such efficacy or effectiveness in this…
- Trial name
- NCT03372668
- Testing
- massage therapy combined with components of mirror therapy
- Volunteers
- 3 people
- Sponsor
- Indiana University
Hip Fractures, Regional Anesthesia
Comparison of PENG Block and FICB in Hip Fracture Patients
Fascia iliaca compartment block (FICB) has been considered the block of choice for patients with hip fracture. However, pericapsular nerve group (PENG) block, one of the relatively newly-developed blocks, could be also used for…
- Trial name
- NCT04677348
- Testing
- Pericapsular nerve group (PENG) block, Fascia iliaca compartment block (FICB)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Asan Medical Center
Greater Trochanteric Pain Syndrome of Both Lower Limbs, Gluteal Tendinitis
Reliability, Validity, and Cross-cultural Adaptation of the Turkish Version of the Victorian Institute of Sports Assessment for Gluteal Tendinopathy (VISA-G) Questionnaire
The purpose of this study was to investigate adaptation, validity, and reliability of the Turkish version of the Victorian Institute of Sports Assessment for Gluteal Tendinopathy (VISA-G) Questionnaire.
- Trial name
- NCT04707274
- Testing
- Survey study
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Gazi University
Tibial Fractures, Leg Injuries
Light Therapy in the Treatment of Leg Pain
The purpose of this study is to apply Anodyne therapy to active duty soldiers, who have shin splints, to evaluate healing time and effectiveness.
- Trial name
- MilCAM (NCT00253981)
- Testing
- Monochromatic Near-Infrared Light Energy (MIRE)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Samueli Institute for Information Biology
Anterior Cruciate Ligament Injury, Pain; Catheter (Other)
On-Q Catheter Caregiver Education
The present study aims to compare caregiver satisfaction and efficacy between two modes of patient education materials (PEMs): media based and print based.
- Conditions
- Anterior Cruciate Ligament Injury, Pain; Catheter (Other), Satisfaction, Personal
- Trial name
- NCT03372889
- Testing
- Patient educaiton materials - Print based, Patient educaiton materials - Media based
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- University of Colorado, Denver