Clinical trials: Lower Extremity Surgery
Lower Limb Surgeries
Effect of Height Based vs Conventional Dose of Spinal Anesthesia in Lower Limb Surgeries
This study aim is to compare height based dose of spinal anesthesia vs conventional dose. Hypothesis is height based dose has less hemodynamics changes compared to conventional dosing.
- Trial name
- NCT07751835
- Testing
- Height based dose of hyperbaric bupivacaine 0.5%
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Liaquat National Hospital & Medical College
Lower Extremity Surgery, Patient Education
Effect of Teach-Back-Based Discharge Education in Lower Extremity Surgery Patients
This study aims to determine the effect of discharge education based on the Teach-Back method on patients' learning needs and readiness for hospital discharge following lower extremity surgery.
- Conditions
- Lower Extremity Surgery, Patient Education, Postoperative Care
- Trial name
- NCT07558070
- Testing
- Teach-Back Education, Routine Discharge Education
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Preoperative Anxiety
The Effectiveness of Warm Hand Bath in Improving Anxiety
Patients undergoing surgery often experience anxiety before the procedure. The aim of this study is to investigate the effectiveness of warm water baths in reducing preoperative anxiety levels in middle-aged and elderly patients…
- Trial name
- NCT06041672
- Testing
- Warm Water Hand Baths
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Cathay General Hospital
Soft Tissue Sarcoma, Bone Sarcoma
Assessment of the Functional Outcome and Quality of Life in Sarcoma Patients
Primary bone and soft tissue sarcomas are an exceptionally rare form of cancer, collectively accounting for only 1% of all malignancies diagnosed.
- Trial name
- QOLSarcoma (NCT05051059)
- Testing
- Functional outcome, Health related quality of life (HRQoL) assessment
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pain, Ankle Injuries
Erector Spinae Plane Block and Ankle and Foot Surgery
Regional anesthesia is commonly used in orthopedic and surgical procedures in ankle and foot surgery to manage pain. The ultrasound-guided nerve block is a safe and effective regional anesthesia technique that provides effective…
- Trial name
- NCT05708742
- Testing
- Ultrasound, Bupivacaine Hydrochloride, saline solution
- Where
- Egypt
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Patellar Dislocation
The Unstable Kneecap - the Impact of Anatomy on Function
The principal objective of the study is to find out which everyday activities make the kneecap unstable in people with patellofemoral instability.
- Trial name
- SPRING (NCT02569931)
- Testing
- Gait analysis, Electromyography, Intra-operative tracking and pressure measurements
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Hip Fractures
Patient-Centered Education After Hip Fracture Surgery
This randomized controlled trial aims to evaluate the effect of a structured patient-centered educational program on postoperative outcomes among patients undergoing hip fracture surgery.
- Trial name
- PCE-HFS (NCT07739225)
- Testing
- Structured Patient-Centered Educational Program.
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hip Fractures, Anticoagulants and Bleeding Disorders
Caudal Block & Hip Fracture Surgery in Anticoagulated Patient
Hip fractures are common in elderly patients, and require surgery. Many elderly patients take anticoagulants for vasculopathy treatment.
- Trial name
- NCT05946863
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Salem Anaesthesia Pain Clinic
Hip Fractures, COVID-19
Anesthesia Technique in COVID-19 Positive Hip Fracture Patients
Patients with COVID undergoing hip fracture repair have high mortality rates. If spinal anesthesia is associated with decreased rates of mortality, this study could provide hypothesis generating data for prospective studies.
- Conditions
- Hip Fractures, COVID-19, General Anesthesia, Spinal Anesthesia
- Trial name
- NCT05133648
- Testing
- Hip Fracture Surgery, COVID-19 infection
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Opioid Use, Pain, Postoperative
Comparison of Pain Relief After Hip Fracture Surgery: Hip and Groin Nerve Block
This observational prospective double-blind study aims to compare the analgesic effectiveness of the pericapsular nerve group block (PENG) group and the suprainguinal fascia iliaca compartment block(SFICB) group to be applied to…
- Conditions
- Opioid Use, Pain, Postoperative, Hip Fractures
- Trial name
- NCT06443892
- Testing
- Pericapsular Nerve Block (PENG), Suprainguinal Fascia Iliaca Compartment Block (SFICB)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Diabetes Mellitus, Diabetic Neuropathy
Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients
This prospective observational study aims to evaluate the effects of ultrasound-guided ankle block on sensory and motor block characteristics and postoperative analgesic outcomes in patients undergoing lower extremity surgery.
- Conditions
- Diabetes Mellitus, Diabetic Neuropathy, Postoperative Pain Management
- Trial name
- ANKLE-DM (NCT07404124)
- Testing
- Ultrasound-Guided Ankle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Wound of Skin, Non-melanoma Skin Cancer
Efficacy and Safety of a Nanofat-seeded Biological Scaffold in Healing Lower Limb Surgical Defects
Large full-thickness skin defects, such as those resulting from trauma, large and giant congenital nevi, disfiguring scars, or tumor resection remain major clinical problems to patients and physicians.
- Conditions
- Wound of Skin, Non-melanoma Skin Cancer, Skin Graft Complications, Wound of Lower Leg
- Trial name
- NCT03548610
- Testing
- Nanofat-seeded biological scaffold on surgical defect
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Anterior Cruciate Ligament Rupture
BFRT in Adolescents After ACL Reconstruction
This is an interventional study that will examine effects of blood flow restriction training (BFRT) in adolescents aged 12-18 after anterior cruciate ligament reconstruction surgery (ACLR).
- Trial name
- NCT04390035
- Testing
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Proximal Femoral Fracture, Dinamic Hip Surgery
Motion Graphic Training for Scrub Nurses in Hip Surgery
This pilot randomized controlled trial evaluates the effect of motion graphic video-based training on the performance of scrub nurse students during dynamic hip screw (DHS) surgery.
- Trial name
- NCT07701564
- Testing
- Motion Graphic Video Training, Routine Clinical Training
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Arak University of Medical Sciences
Intraoperative Complications
Liberal Versus Restrictive Fluid Protocols in Adults
The term acute kidney injury (AKI) is used to describe a rapid deterioration (hours to days) of renal function. This rapid deterioration leads to accumulation of plasma waste products, such as urea and creatinine.
- Trial name
- NCT03697330
- Testing
- Ringer lactate
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Anesthesia, ERAS
Goal-Directed Fluid Therapy in Patients Undergoing Lower Limb Surgeries
Controlling the amount of fluids given to patients in perioperative setting can significantly influence their outcomes.
- Conditions
- Anesthesia, ERAS, Fluid Overload, Hypovolemia; Surgical Shock
- Trial name
- NCT06133257
- Testing
- Goal-Directed Fluid Therapy guided by Inferior Vena Cava Collapsibility Index, standard fluid management
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Anesthesia, Spinal
Caval-aorta Index and Perfusion Index on Predict Hypotension After Spinal Anaesthesia in Elderly
The aim of our study was to predict hypotension by using caval aorta index and perfusion index in elderly patients who may develop hypotension after spinal anesthesia.
- Trial name
- NCT06479512
- Testing
- ultrasonography to measure the index of the caval aorta and non-invasive pulse oximetry for perfusion index
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Learning Curves and Outcomes of Simulation-based Training
Is Two-on-one Instruction in Virtual Reality Simulation-based Training of Operating Fractures of the Hip for Medical Students as Effective as One-on-one Instruction
The training of orthopedic surgeons has historically relied heavily on an apprenticeship model as the primary way of teaching the various procedures an aspiring surgeon needs to master.
- Trial name
- NCT06612619
- Testing
- Dyad instruction
- Where
- Denmark
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Lumbar Radiculopathy, Lumbar Herniated Disk
Does Intraoperative Application of Steroids Affect Early Outcomes in Patients Undergoing Endoscopic Lumbar Discectomy?
Prospective randomised trial assessing whether intraoperative application of steroids leads to better clinical outcomes in patients submitted to lumbar discectomy
- Trial name
- NCT07411326
- Testing
- Intervention Group, Control group (Normal Saline) (C)
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar De São João, E.P.E.
Degenerative Joint Disease, Osteoarthritis
Comparison of Clinical Outcomes and Performance of Total Knee Replacement Patients Before and After Surgery
This study is to determine the relevancy of clinical scales for outcome measures as compared to flexion angle and other gait measures.
- Conditions
- Degenerative Joint Disease, Osteoarthritis, Knee Injury, Trauma, Connective Tissue Disorder
- Trial name
- TKR (NCT01379118)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loma Linda University