Clinical trials: Lower Extremity Ulcer
Diabetic Foot Infection, Osteomyelitis
A Clinical Trial Testing the Efficacy of PDT in Preventing Amputation in Diabetic Patients
The feet of diabetic patients continue to be an important problem in medicine. In general, patients with diabetic foot have some sort of amputation, especially in underserved populations.
- Conditions
- Diabetic Foot Infection, Osteomyelitis, Photo Antimicrobial Chemotherapy
- Trial name
- NCT03380403
- Testing
- PDT, Ciprofloxacin
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Faculdade de Medicina do ABC
Diabetic Foot, Type 2 Diabetes Mellitus With Established Diabetic Nephropathy
The Effectiveness of Improving Self-care After Counseling for the Diabetics Mellitus Foots Around Chiayi Region
Objectives: Preventing diabetic foot problems (DFP) and associated consequences, such as amputation, is a critical in rural regions.
- Trial name
- NCT01299246
- Testing
- Michigan Neuropathy Screening Instrument
- Where
- Taiwan
- Volunteers
- 386 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Diabetes
Investigating Ultrasound Debridement in Wound Care
The initial step of wound management, debridement, is thought to be critical in promoting wound healing. Of the numerous debridement modalities, ultrasound seems to hold promising results in accelerate healing in our own clinical…
- Trial name
- NCT03516422
- Testing
- ULTRASOUND DEBRIDEMENT, STANDARD CARE GROUP
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Diabetic Complications, Foot Care
Evaluation of Materials for the Distribution of Pressure in the Treatment of Neuroischemic Ulcers
The hypothesis of this study is based on the premise that pressure-distributing materials with superior biomechanical and tissue response properties will be capable of improving the healing rate of neuropathic ulcers.
- Trial name
- NCT07620379
- Testing
- felt padding
- Where
- Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Venous Stasis, Deep Venous Thrombosis
Effects of External Leg Compression Devices on Healing and Blood Clotting
This study aims to compare two different external calf compression devices applied in healthy individuals. These devices are commonly used in medical care in order to prevent the formation of blood clots, for example during…
- Conditions
- Venous Stasis, Deep Venous Thrombosis, Healing Wound
- Trial name
- NCT03050671
- Testing
- Intermittent Pneumatic Compression, Rapid, Intermittent Pneumatic Compression, Slow
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Diabetic Neuropathies, Distal Peripheral Sensory Neuropathy
Diabetic Neuropathy Screening Study 1.1 + Substudy 1.2-1.3-1.4
The overall objective of this project is to describe the prevalence of and risk factors to diabetic neuropathy in a representative cohort of diabetes patients and to investigate pathophysiological conditions in those patients…
- Conditions
- Diabetic Neuropathies, Distal Peripheral Sensory Neuropathy, Diabetic Foot, Foot Deformities
- Trial name
- DANES (NCT05043636)
- Testing
- Vagus, HeartsTrends, Sudoscan
- Where
- Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
Diabetic Foot, Diabetes Mellitus, Type 2
Foot-Ankle Exercise and Walking Exercise on Diabetes Mellitus Patients
The primary purpose of this study is to determine the effectiveness of foot-ankle exercise and walking exercise on foot neuropathy, stress, and quality of life (QoL) among people with diabetes mellitus (PWDM).
- Conditions
- Diabetic Foot, Diabetes Mellitus, Type 2, Diabetic Neuropathies, Diabetes Type 2
- Trial name
- NCT06518486
- Testing
- Foot-ankle exercise, Walking exercise, Usual care and health education
- Where
- 5 sites in Indonesia
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Non-healing Wounds
Effect of Natrox Oxygen Wound Therapy on Non-healing Wounds and Implication of Remote Monitoring and Telehealth for Management in the Home.
Single center pilot study examining the effect of Natrox topical oxygen therapy on chronic wounds along with the introduction of remote monitoring and telehealth for home care management.
- Trial name
- NCT04746573
- Testing
- Natrox Topical Oxygen Therapy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Inotec AMD Limited
Lower Limb Ulcers
VergenixTM Flowable Gel in Patients With Lower Limb Ulcers
Vergenix Flowable Gel is indicated for the management of acute and chronic wounds
- Trial name
- CP-FG-001 (NCT02598180)
- Testing
- VergenixTM Flowable Gel
- Where
- 4 sites in Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Collplant
Diabetic Polyneuropathy, Diabetic Foot
The Effect of Mini Trampoline Exercise Program on Diabetic Foot Care Behavior and Polyneuropathy
This study was planned to examine the effect of home-based mini trampoline exercise program on diabetic foot care behavior and diabetic polyneuropathy in Type 2 diabetes patients.
- Conditions
- Diabetic Polyneuropathy, Diabetic Foot, Type 2 Diabetes
- Trial name
- NCT05668325
- Testing
- Mini trampoline exercise group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Diabetic Foot Ulcers
A Pilot Study of the Provant Therapy System in Subjects With Diabetic Foot Ulcers
The objective of this study is to compare the reduction in wound surface areas between patients with diabetic ulcers utilizing Provant's pulsed radio frequency energy therapy (PRFE) as an adjunct to standardized basic wound care…
- Trial name
- NCT00761176
- Testing
- The Provant Therapy System
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Regenesis Biomedical, Inc.
Diabetic Foot Ulcer
Motivational Interview Based Discharge Planning for Patients With Diabetic Foot Ulcers
To evaluate the effectiveness of a discharge planning using the strategy of motivational interviewing among patients with diabetic foot ulcers
- Trial name
- NCT04467606
- Testing
- a discharge planning using the strategy of motivational interviewing
- Where
- Taiwan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Type2diabetes, Diabetic Foot
THE EFFECT OF ONLINE TRAINING ON FOOT CARE
The aim of this study is to determine the effect of online trainings on diabetic foot care on foot care behavior and self-efficacy attitudes of individuals with type II diabetes.
- Trial name
- NCT05473494
- Testing
- training group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Venous Ulcer, Low-Level Light Therapy
Low-level Light Therapy on Treatment of Venous Ulcers Assesed by Nursing Outcome Classification (NOC)
This study compares the effect of adjuvant treatment of Low-level Light Therapy with conventional treatment in the tissue repair of venous ulcers in patients undergoing outpatient nursing consultation.
- Trial name
- LASERUVe (NCT03229330)
- Testing
- Low-level Light Therapy, Conventional treatment
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Venous Leg Ulcer, Venous Stasis
SkinTE® in the Treatment of Venous Leg Wounds
This study is a prospective, multi-center, randomized controlled trial designed to collect patient outcome data on a commercially available human autologous homologous skin construct with SOC dressing compared to SOC dressings…
- Conditions
- Venous Leg Ulcer, Venous Stasis, Venous Stasis Ulcer
- Trial name
- NCT03881267
- Testing
- Human Autologous Homologous Skin Construct, Additional Outer Dressing Application, Fibracol Wound Dressing
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- PolarityTE
Foot, Foot Orthoses
Custom Foot Orthoses & Venous Status
The purpose of the research is to compare the influence of customized foot orthoses use on the venous status among healthy female and male subjects. This is a quasi-experimental study which included 20 healthy subjects.
- Conditions
- Foot, Foot Orthoses, Photoplethysmography, Venous Stasis
- Trial name
- NCT03329430
- Testing
- Foot orthoses
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad de León
Treatment of Leg Ulcer, Sharp Debridement
Treatment of Chronic Leg Ulcer in Outpatient's Department and i Primary Care - Wound Size and Inflammation
The purpose of this study is to investigate the rate of wound healing using sharp debridement using curette and to compare between such intensive treatment at hospital and treatment in primary care.
- Conditions
- Treatment of Leg Ulcer, Sharp Debridement, Proinflammatory Cytokines
- Trial name
- NCT01249495
- Testing
- Sharp debridement
- Where
- Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Chronic Wounds With Different Etiologies
Swab Sample Collection for the Detection of Bacterial Proteases in Wounds Assay
The objective of this study is to collect wound exudate (fluid) swab samples from Subjects who have wounds that show clinical signs of infection, as well as from Subjects who have wounds that do not show clinical signs of…
- Trial name
- NCT01750203
- Testing
- Swabs
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Systagenix Wound Management
Venous Ulcers
Clinical Implications of Genetic Variations of Venous Stasis Ulceration
Currently, there is no standard approach for the treatment of patients with venous stasis ulcers, and no means of accounting for the genetic factors that may contribute to a patient's response to different therapeutic…
- Trial name
- NCT02034396
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 377 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Diabetic Foot Ulcer
Plantar Pressure Distribution in Diabetic Foot Ulcer
The goal of this clinical trial is to find out the changes in peak pressure and pressure-time integral after twelve weeks from the initial utility of foot insoles and eight weeks later as a follow-up in diabetic foot ulcers.
- Trial name
- PPDDFU (NCT05888259)
- Testing
- foot insole
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University