Clinical trials: Lower Gastrointestinal Symptoms
Rectal Neoplasms, Sexual Dysfunction
Robotic Versus Laparoscopic Low Anterior Resection for Rectal Cancer
Prospective randomized trial comparing robotic versus laparoscopic Low anterior resection for rectal cancer. Primary endpoint: Compare urinary dysfunction between robotic and laparoscopic approach.
- Conditions
- Rectal Neoplasms, Sexual Dysfunction, Urinary Incontinence, Quality of Life
- Trial name
- RAR (NCT03209076)
- Testing
- Robotic, Laparoscopic
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
GERD, Morbid Obesity
Management of Reflux After Sleeve Using Stretta
Gastroesophageal reflux disease (GERD) is a frequently seen entity after sleeve gastrectomy. Management of GERD after sleeve is difficult given limited treatment modalities.
- Trial name
- MaRSS (NCT02637713)
- Testing
- Stretta, Radiofrequency (RF) Energy to the LES (Stretta Procedure)
- Where
- 13 sites in United States
- Volunteers
- 5 people
- Sponsor
- Montefiore Medical Center
Liver Transplantation, Resistance Training
Study of Resistance Strengthening Versus Ambulation Post-Liver Transplant
Resistance strengthening exercise will increase strength and functional activity greater than ambulation in subjects post-liver transplantation.
- Conditions
- Liver Transplantation, Resistance Training, Activities of Daily Living
- Trial name
- NCT01216722
- Testing
- Resistance Strengthening Exercise Program
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Miami
Diverticulitis, Colonic
Unexpected Diagnosis in Right Lower Quadrant Pain: Right Colon Diverticulitis
BACKGROUND: Acute right lower quadrant pain is a common symptom in emergency departments. The most common etiology is thought to be acute appendicitis. Other etiologies may be overlooked.
- Trial name
- NCT06153030
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Laparoscopic Surgery
Short Title: Standard vs. Lower Pressure Pneumoperitoneum
This study aims to investigate the effect of varying insufflation pressures on post-operative pain and adequacy of surgical field visualization among patients undergoing laparoscopic surgery with a minimally invasive gynecologic…
- Trial name
- NCT06338865
- Testing
- Carbon dioxide, Bupivacaine, Oxycodone
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- Cedars-Sinai Medical Center
Adenomyosis, Uterine Leiomyoma
The Association Between Adenomyosis/Uterine Myoma and Lower Urinary Tract Symptoms
The aim of this study is to assess the relationship between adenomyosis/myoma and lower urinary tract symptoms, sexual function and gastrointestinal symptoms.
- Trial name
- NCT02495311
- Testing
- myomectomy or adenomyomectomy
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Urinary Incontinence, Vitamin D Deficiency
Vitamin D Supplementation in Older Adults With Urinary Incontinence
Urinary incontinence (UI) is a common disorder among older women that greatly affects quality of life. Emerging evidence from observational studies links vitamin D insufficiency with UI.
- Trial name
- NCT01971801
- Testing
- Vitamin D3 50,000 IU
- Where
- United States
- Volunteers
- 243 people
- Sponsor
- University of Alabama at Birmingham
Ovarian Endometrioma
The Association Between Ovarian Endometrioma and Lower Urinary Tract Symptoms
To assess the relationship between ovarian endometrioma and lower urinary tract symptoms, sexual function and gastrointestinal symptoms.
- Trial name
- NCT02623244
- Testing
- Laparoscopic oophorocystectomy or oophorectomy
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Cystic Fibrosis (CF), Cystic Fibrosis in Children
Physical Impairments in Children With Cystic Fibrosis
It is aimed to reveal impairments regarding urinary incontinence, dyspnea, muscle strength, functional capacity or quality of life in children and adolescents with cystic fibrosis compared to healthy children and adolescents.
- Trial name
- NCT06984679
- Testing
- Physical Evaluations in Children with Cystic Fibrosis, Physical Evaluations in Healthy Children
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Izmir Democracy University
Urinary Incontinence, Cystocele
Enhanced Recovery Protocol in Urogynecologic Surgery
Enhanced recovery after surgery (ERAS) has been shown to improve postoperative outcomes in a variety of surgical conditions. However, data regarding its role in urogynecologic surgery is limited.
- Conditions
- Urinary Incontinence, Cystocele, Rectocele, Pelvic Organ Prolapse
- Trial name
- NCT04175782
- Testing
- Enhanced recovery after surgery (ERAS) protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Overactive Bladder, Urinary Incontinence
Percutaneous Nerve Evaluation With Fluoroscopy Versus Without
The investigators propose a randomized control trial comparing the rate of implantation of the InterStim device following Percutaneous Nerve Evaluation (PNE) performed with or without fluoroscopic guidance.
- Conditions
- Overactive Bladder, Urinary Incontinence, Fecal Incontinence
- Trial name
- NCT02677753
- Testing
- Fluoroscopy
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Urinary Incontinence, Urinary Incontinence, Urge
Safety and Performance of UCon Bar Electrode for the Treatment of Overactive Bladder (OAB) and Bowel Dysfunction (BD)
UCon is a medical device for treatment of the symptoms of overactive bladder (OAB) and bowel dysfunction (BD). It electrically stimulates the DGN through the skin to obtain modulated behaviour of the bladder/bowel musculature…
- Conditions
- Urinary Incontinence, Urinary Incontinence, Urge, Fecal Incontinence, Fecal Incontinence With Fecal Urgency
- Trial name
- NCT06091566
- Testing
- UCon-Bar
- Where
- 3 sites in Denmark
- Volunteers
- 20 people
- Sponsor
- InnoCon Medical
Urinary Incontinence, Fecal Incontinence
Incontinence Management System ICU Field Evaluation
The objective of this Field Evaluation is to assess usage and satisfaction associated with the Hill-Rom Incontinence Management System.
- Trial name
- NCT03628833
- Testing
- Incontinence Management System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Hill-Rom
Pelvic Organ Prolapse, Urinary Incontinence
Validation of a French Version of the PISQ-R
The main objective of this study is to perform the linguistic validation of the french version of the PISQ-R questionnaire in a population of sexually active (or not) patients who have undergone surgery (or not) for stress…
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Fecal Incontinence
- Trial name
- NCT01548976
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Advanced Heart Failure, Left Ventricular Assist Devices
Trial of Low-intensity Anticoagulation to Reduce GI or Other Bleeding Complications With Equivalent Therapeutic Efficacy in HeartMate 3 LVAD Patients
The TARGET trial is a prospective, single-center, randomized, open-label, active-controlled inequality clinical trial designed to evaluate the safety and efficacy of low-intensity anticoagulation therapy (target INR 1.5-2.0)…
- Conditions
- Advanced Heart Failure, Left Ventricular Assist Devices, Anticoagulation Treatment, Bleeding Complications
- Trial name
- TARGET (NCT07081035)
- Testing
- Warfarin (low-intensity anticoagulation), Warfarin (standard anticoagulation)
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Asan Medical Center
Crohn's Disease
Cimzia Versus Mesalamine for Crohn's Recurrence
Hypothesis: Cimzia provides superior reduction in endoscopic and clinical recurrence rates compared to mesalamine in the treatment of Crohn's disease one-year following ileocolectomy for Crohn's disease. 1.
- Trial name
- NCT01696942
- Testing
- Cimzia, Mesalamine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Milton S. Hershey Medical Center
Prolapse, Urinary Incontinence
What is the Prevalence of Female Pelvic Floor Disorders in Minnesota?
To determine the prevalence of pelvic organ prolapse and urinary incontinence among women in Minnesota using a short web-based self-administered questionnaire.
- Conditions
- Prolapse, Urinary Incontinence, Fecal Incontinence, Bladder Pain Syndrome
- Trial name
- NCT03536221
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Urinary Incontinence, Cystic Fibrosis
Cystic Fibrosis and Urinary Incontinence
Evaluate the feasibility of a randomized controlled trial of non-surgical urinary incontinence (UI) management options for women with CF.
- Trial name
- NCT04922255
- Testing
- Reusable Underwear, Disposable urethral support, Pelvic floor physical therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Megan Bradley
Spinal Tumor
A Prospective Study Using Implanted Fiducial Markers to Assess Treatment Accuracy and Esophageal Toxicity in Spinal Stereotactic Body Radiation Therapy
The goal of the first part of this clinical research study is to learn how to deliver more accurate radiation treatment of tumors in the spine.
- Trial name
- NCT01624220
- Testing
- Spinal SBRT (Standard Dose), Spinal SBRT (Higher Dose), Gold Seed Implantation
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- M.D. Anderson Cancer Center