Clinical trials: Lower Limb Injury
ACL, Anterior Cruciate Ligament Injury
Decreasing Knee Injury Risk Factors With Neuromuscular Training
Anterior cruciate ligament (ACL) tears are disabling injuries that place a significant burden on the athlete. Roughly 80% of these injuries are linked to a noncontact mechanism, with more than 70% of them occurring while landing…
- Trial name
- NCT01433718
- Testing
- Neuromuscular and Resistance Training
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio University
Femoral Neck Fractures
Topical (Intra-Articular) Tranexamic Acid and Transfusion Rates Following Hip Hemiarthroplasty
This study is a double-blinded placebo-controlled clinical trial evaluating the efficacy of 1 gram of topically applied tranexamic acid vs. saline placebo for the reduction of transfusion following hip hemiarthroplasty surgery.
- Trial name
- NCT02664909
- Testing
- Tranexamic Acid
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- UConn Health
Hip Fractures, Gait, Unsteady
Comparison of Sliding Hip Screw to Intra Medullary Nailing in the Treatment of Intertrochanteric Hip Fracture
Shortening of the abductor lever arm is a particular concern with the SHS, and the resultant biomechanical alterations may impair gait, including decreased cadence, gait speed and increased double support time on the injured…
- Conditions
- Hip Fractures, Gait, Unsteady, Function
- Trial name
- NCT03906032
- Testing
- TFNA IM Nail, Sliding hip screw
- Where
- Ireland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Waterford
Anterior Cruciate Ligament Rupture, Knee Instability
Single and Double Bundle ACL Reconstructions, in Term of Cartilage Damage Due to Remaining Instability After Surgery.
The prevalence of ACL (Anterior Cruciate Ligament) ruptures is relatively high, primarily due to sports and military training injuries.
- Conditions
- Anterior Cruciate Ligament Rupture, Knee Instability, Cartilage Damage
- Trial name
- ACL (NCT04626999)
- Testing
- Single Bundle ACL Reconstruction, Double Bundle ACL Reconstruction
- Where
- Indonesia
- Volunteers
- 52 people
- Sponsor
- Universitas Indonesia
Femoral Neck Fractures, Internal Fixation
Three Cancellous Screws Versus Four Cancellous Screws for Femoral Neck Fixation
This study is a prospective randomized controlled clinical study. Patients with femoral neck fracture (AO classification 31-B) will be randomly divided into three-screw fixation group and four-screw fixation group.
- Trial name
- NCT04869332
- Testing
- three cancellous screws, four cancellous screws
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Peking University Third Hospital
Ankle Fractures
RCT Comparing Non-operative vs Operative Treatment of Suprasyndesmotic Ankle Fractures.
Weight-bearing radiographs will be used to evaluate the stability of suprasyndesmotic ankle fractures. Patients with stable fractures will be randomised to operative or non-operative treatment.
- Trial name
- NCT04615650
- Testing
- Surgical treatment, Ankle orthosis
- Where
- 4 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Sykehuset Innlandet HF
Shin Splint, Fascial Manipulation
Observing the Effect of Fascial Manipulation in Athletes With Shin Splits.Tibial Stress Syndrome.
Aims \& objectives: 1. The aim of the study is to find out the influence of fascial manipulation on running kinematics among athletes with medial tibial stress syndrome (MTSS). 2. The objectives of our study are i.
- Conditions
- Shin Splint, Fascial Manipulation, Running Kinematics
- Trial name
- MTSS (NCT03198260)
- Testing
- Fascial manipulation
- Where
- India
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Manipal University
Ankle Injuries
MRI Appearance of Injured Ligament and Tendon of the Ankle in Different Postures
To compare the results of multi-position MRI scans for ankle ligaments and tendons to clarify how to obtain imaging data of different ankle ligaments and define severity of injuries to calculate the rate of correct diagnosis…
- Trial name
- NCT03049423
- Testing
- MRI scans, MRI scans and general physical examination
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Hebei Medical University
Osteoporosis Risk, Fracture of Femur
Prediction Model of Hip Fragility Fracture Realistic Data From a Traumatology Department and Orthogeriatric Ward.
The aim of the project is to build a prediction model of hip fragility fracture using hospital data routinely collected in the traumatology department from the last 12 years and up to date Explainable Artificial Intelligence…
- Conditions
- Osteoporosis Risk, Fracture of Femur, Fragility
- Trial name
- NCT06545487
- Testing
- BLOOD SAMPLE
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Knee Injuries
New MRI Measurement of Patellar Height in Knee Extension - IES-EV Control Study
The measurement of the patellar height is essential to decide and quantify the surgical correction to be made. The classic index is that of Cato and Deschamps.
- Trial name
- NCT05659316
- Testing
- MRI imaging
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Pain, Acute, Pain, Chronic
Evaluation of the Effect of the AI500™ SINGLE-DOSE GEL Medical Device in Patients With Reduced Knee Function
Evaluation of the effect of the AI500™ SINGLE-DOSE GEL medical device in patients with reduced knee function
- Conditions
- Pain, Acute, Pain, Chronic, Knee Injuries, Knee Osteoarthritis
- Trial name
- NCT05886608
- Testing
- AI 500™ SINGLE-DOSE GEL
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Contrad Swiss SA
Muscle Injury, Lower Limb Injury
Effects of ART® on Lower Limb Myofascial Pain and Function
This is a feasibility study to determine if the investigators can conduct a clinical trial with a sham and control soft tissue treatment.
- Trial name
- NCT04535635
- Testing
- Active Release Techniques®
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Canadian Memorial Chiropractic College
Hip Fracture of Intertrochanteric Type, Thromboembolic Event
Diffrence in Thromboprofilaksis in Elderly Ostoepenic Hip Fractures According to Mobility Status by Genetic Analysis
Hip fracture is a common and severe disease in elderly patients. The question of the study is whether elderly patients with severe osteopenia have significantly lower levels of the collagen-binding protein Hsp47 than relatively…
- Conditions
- Hip Fracture of Intertrochanteric Type, Thromboembolic Event, Osteopenia, Thrombosis Embolism
- Trial name
- HSP 47 (NCT06959017)
- Testing
- Gene Expression Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Femoral Neck Fractures, Breathing Exercises
Effect of Liuzijue and Box Breathing on Inspiratory Capacity and Blood Pressure After Femoral Neck Fracture Immobilization
The purpose of this study is to understand how two simple breathing exercise techniques (Liuzijue and box breathing) affect inspiratory capacity and blood pressure in people who were immobilized after a femoral neck fracture.
- Conditions
- Femoral Neck Fractures, Breathing Exercises, Inspiratory Capacity, Blood Pressure
- Trial name
- NCT07389291
- Testing
- Liuzijue Qi Gong Exercise, Box Breathing Technique
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Saveetha University
Shin Splint
Release Versus Post Isometric Relaxation Among Futsal Players With Shin Splints
The aim of the study is to determine the effects of myofascial release versus post isometric relaxation among futsal players with shin splints
- Trial name
- NCT05931510
- Testing
- Myofscual release, Post isometric relaxation.
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Spinal Cord Injuries
Functional Electrical Stimulation During Cycling in People With Spinal Cord Injury
Neuroscience research that has identified potential for recovery (neuroplasticity) following incomplete SCI has changed clinical practice away from compensation strategies towards optimizing recovery.
- Trial name
- iCycle (NCT03834324)
- Testing
- FES
- Volunteers
- 11 people
- Sponsor
- University of Southampton
Accidental Fall, Fall
Remote Monitoring and Analysis of Gait and Falls Within an Elderly Population
The investigators aim to do this initial pilot study as an observational prospective cohort study, evaluating elderly patients who have capacity in National Health Service (NHS) rehabilitation and community hospitals.
- Conditions
- Accidental Fall, Fall, Fall Injury, Hip Fractures
- Trial name
- 4279 (NCT03680014)
- Testing
- CUSH
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CUSH Health Ltd.
Distal Humerus Fracture, Distal Femur Fracture
3D-printed Bone Models in Addition to CT Imaging for Intra-articular Fracture Repair
The purpose of this study is to compare the effectiveness of 3D-printed bone models in addition to CT imaging versus CT imaging alone on surgical quality and operation time for patients undergoing surgical repair of…
- Conditions
- Distal Humerus Fracture, Distal Femur Fracture, Distal Tibia Fracture, Proximal Humeral Fracture
- Trial name
- SPRINT (NCT04748016)
- Testing
- 3D printed (3DP) bone models + CT imaging, CT imaging
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Hip Fractures, Hip Injuries
Retrospective Evaluation of Efficacy of Meta-PENG Block
The components of the lumbar plexus and capture the articular branches of hip capsule may be effectively blocked by administering a relatively high volume of local anesthetic deep to the iliacus muscle at the level of the…
- Trial name
- NCT06721052
- Testing
- meta-Peng block, Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 7 people
- Sponsor
- Medipol University
Anterior Cruciate Ligament Rupture, Ligament Knee Injury
Combined Intra- and Extra-articular ACL Reconstruction Versus Isolated Intra-articular ACL Reconstruction
Abstract Introduction: Autologous hamstring tendons are the most commonly used grafts in ACL reconstruction worldwide. There are several ways to prepare the graft using these tendons.
- Trial name
- NCT06505525
- Testing
- Extra-articular reconstruction with the Anterolateral Ligament
- Where
- 2 sites in Brazil
- Volunteers
- 146 people
- Sponsor
- Federal University of São Paulo