Clinical trials: Lower Limb Pain
Arthroplasty, Replacement, Knee, Knee Injuries
ALGRX 4975 After Total Knee Replacement
ALGRX 4975 or placebo will be dripped onto the cut muscles and soft tissues before the end of surgery for total replacement of the knee.
- Trial name
- NCT00132392
- Testing
- ALGRX 4975
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- AlgoRx Pharmaceuticals
Pain, Total Knee Arthroplasty
Duration of Leg Nerve Blocks With Dexamethasone Added to Local Anesthetic
This is a Randomized Double blinded controlled trial on the effect of adding dexamethasone to Ropivacaine on the duration of pain relief for ultrasound guided femoral, obturator and popliteal block after total knee replacement…
- Trial name
- NCT01511211
- Testing
- Dexamethasone, Ropivacaine
- Where
- United States
- Sponsor
- University of New Mexico
Vascular Surgical Procedures
Pain Management of Amputation Wounds With AutoHypnosis
Amputation in vascular surgery mainly concerns the lower limb and is often linked to Obliterative Arterial Disease of the Lower Limbs.
- Trial name
- MODOUPAAH (NCT05779852)
- Testing
- self-hypnosis and dressing, dressing
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Rennes University Hospital
Skin Laceration, Skin Abrasion
Retrospective, Observationnal Study to Investigate Procedural Analgesia Delivered to Patients With Lacerations, Abrasions, Burns and Leg Ulcers.
The main part of the study is a retrospective analysis of 200 reports concerning patients with skin wounds and injuries : 50 consecutive patient reports dealing with skin lacerations 50 consecutive patient reports dealing with…
- Conditions
- Skin Laceration, Skin Abrasion, Skin Burn, Leg Ulcer
- Trial name
- APPABU (NCT07350811)
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Versailles Hospital
Orthopedic Procedures, Pain, Postoperative
Risk Model for Severe Rebound Pain After Lower Limb Orthopedic Surgery Involving Single-Shot Sciatic Nerve Blocks
Rebound pain is a well-recognized phenomenon after the effects of a nerve block wear off. Severe rebound pain can happen after outpatient surgery, with patients often needing to come back to the hospital or use other health care…
- Conditions
- Orthopedic Procedures, Pain, Postoperative, Surgery, Nerve Block
- Trial name
- NCT05018104
- Testing
- This is not an interventional study
- Where
- Canada
- Volunteers
- 1,270 people
- Sponsor
- University of British Columbia
Anterior Cruciate Ligament Rupture, Acute Pain
Femoral Triangle + IPACK Blocks for ACL Reconstruction Analgesia
An adequate balance between analgesia and motor function is an essential requirement to facilitate functional recovery and early discharge after anterior cruciate ligament (ACL) reconstruction surgery. Proximal nerve blocks (i.e.
- Conditions
- Anterior Cruciate Ligament Rupture, Acute Pain, Pain, Postoperative, Knee Injuries
- Trial name
- NCT05068063
- Testing
- Bupivacaine Injection, normal Saline
- Where
- 2 sites in Chile
- Volunteers
- 48 people
- Sponsor
- University of Chile
Arthralgia, Trouble Balancing
Even-Up to Minimize Secondary Site Pain For Ankle Fracture
Evaluating impact of use of Even-Up shoe wear device for patients treated in CAM boot walker for an ankle fracture. Randomized controlled trial, randomizing patients into control group with boot treatment only versus boot…
- Trial name
- NCT04164563
- Testing
- Even-Up
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Knee Injuries
Knee Nerve Cryoneurolysis and Impact on Pain After Prosthetic Surgery
Interventional, comparative, randomized, controlled study versus standard treatment, in 3 parallel groups, monocentric, aiming to demonstrate the superiority of preoperative cryoneurolysis versus no procedure, in patients…
- Trial name
- Cryogenou (NCT05059535)
- Testing
- standard pain relievers
- Where
- France
- Volunteers
- 52 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Lower Extremity, Nerve Block
Bupivacaine-Lidocaine vs Bupivacaine for Ultrasound-Guided Popliteal Sciatic Nerve Block
This prospective, randomized, double-blind clinical trial aims to compare the efficacy of two local anesthetic regimens for ultrasound-guided popliteal sciatic nerve block in adult patients undergoing elective distal lower…
- Conditions
- Lower Extremity, Nerve Block, Pain, Postoperative, Pain, Nerve
- Trial name
- PSSNB-BL (NCT07550348)
- Testing
- Bupivacaine-Lidocaine Combination, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Leg Ulcer, Pain
Pain in Chronic Leg- and Foot Ulcers
Leg ulcers are a significant cause of impaired functional ability and quality of life for approximately 1-2 percent of the population in western countries.
- Trial name
- NCT03086577
- Where
- Norway
- Volunteers
- 360 people
- Sponsor
- University College of Southeast Norway
Patellofemoral Pain Syndrome
Effects of Agility Training With and Without Foot Mobilization In Patellofemoral Pain Syndrome.
Patellofemoral pain syndrome (PFPS) is referred to as peripatellar or retro-patellar pain, which is characterized by alterations in the physical and biomechanical features of the patellofemoral joint.
- Trial name
- NCT06674707
- Testing
- Agility Training with Foot mobilization., Agility Training without Foot mobilization
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Low Back Pain, Type of Leg Pain (Radicular, Non-radicular)
The Course of Low Back Pain
This study aims to research the possible associations of education level, sedentary lifestyle, and type of low back pain (radicular vs non-radicular) with the course of low back pain and recovery rate.
- Conditions
- Low Back Pain, Type of Leg Pain (Radicular, Non-radicular), Lifestyle (Sedentary Behavior and Physical Activity), Start Back Screening Tool
- Trial name
- NCT04419675
- Testing
- Observational Cohort, usual care = physical therapy
- Where
- 6 sites in Netherlands
- Volunteers
- 347 people
- Sponsor
- Radboud University Medical Center
Sedentary Lifestyle, Knee Osteoarthritis
NEAT!2 Sedentary Behavior Reduction for Individuals With Past or Present Knee Symptoms, Injuries, or Surgeries
This study will evaluate the effectiveness of an mHealth sedentary reduction program over a 6-month period of time in adults with past or present knee symptoms, injuries, or surgeries.
- Conditions
- Sedentary Lifestyle, Knee Osteoarthritis, Knee Injuries, Knee Pain Chronic
- Trial name
- NCT03987932
- Testing
- NEAT!2, NEAT!2+Calls, Delayed NEAT!2
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Pain, Infant ALL
Effect of Leg and Heel Massage on Pain During Heel Blood Collection Newborns
This study was planned to evaluate the effect of leg and heel massage on newborns, the pain experienced during heel blood collection, and the effects on physiological parameters.
- Trial name
- NCT06567093
- Testing
- Baby Foot and Leg Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Perfusion; Complications, Wound; Foot
Avazzia-University of Texas Southwestern Medical Center-Tennant Biomodulator® PRO Perfusion Study
This study is an open label trial designed to test the effectiveness of the Tennant Biomodulator® PRO electrical stimulation device (Avazzia), which uses BEST™ (Bio-Electric Stimulation Technology), on hospital in-patients to…
- Trial name
- NCT03843307
- Testing
- Avazzia Tennant Biomodulator® PRO
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Avazzia, Inc
Diabetes Mellitus, Diabetic Neuropathy
Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients
This prospective observational study aims to evaluate the effects of ultrasound-guided ankle block on sensory and motor block characteristics and postoperative analgesic outcomes in patients undergoing lower extremity surgery.
- Conditions
- Diabetes Mellitus, Diabetic Neuropathy, Postoperative Pain Management
- Trial name
- ANKLE-DM (NCT07404124)
- Testing
- Ultrasound-Guided Ankle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
CRPS (Complex Regional Pain Syndrome) Type I
Physiological Parameters in CRPS Patients Treated With Dorsal Root Ganglion Stimulation
1. Objective and Rationale: The study seeks to evaluate how Dorsal Root Ganglion Stimulation (DRGS) influences autonomic functions in patients suffering from Complex Regional Pain Syndrome type I (CRPS I), offering new metrics…
- Trial name
- EPIC-DRG (NCT07147140)
- Testing
- dorsal root ganglion stimulation cessation
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- AZ Delta
Iliotibial Band Syndrome
Home-based Treatment Using the Sidekick Tool for Pain Relief in Patients With Iliotibial Band Syndrome
The aim of the study is to test how well the Sidekick Tool works as a home-based pain relief for iliotibial band syndrome using instrument assisted soft tissue mobilization tool in healthy participants aged 18-65 years old.
- Trial name
- NCT06089005
- Testing
- Instrument Assisted Soft Tissue Mobilization device
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hannah Antony
Knee Osteoarthritis
Effectiveness of DN With or Without Mulligan Two Leg Rotation Technique on Pain ROM and Joint Dysfunction in KO
The objective of study is to determine the effectiveness of dry needling with or without mulligan two leg rotation technique on pain, range of motion and joint dysfunction in knee osteoarthritis.
- Trial name
- NCT06739954
- Testing
- Mulligan's Two Leg Rotation technique, Dry Needling
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Superior University
Spinal Cord Stimulation
New Markers to Assess the Efficacity of Spinal Cord Stimulation for the Treatment of Chronic Lower Limb Pain (MOTIVE)
By combining the usual care of patients eligible for spinal cord stimulation (SME) with measurements of the HRV index (Heart Rate Variability), objective measurements of activity (number of steps, quality of sleep) and…
- Trial name
- NCT04785001
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild