Clinical trials: Lower Limb Pain
Varicose Veins of Lower Limb, Chronic Venous Insufficiency, CVI
Knee Pain Relief After Endovenous Treatment for Lower Limb Varicose Veins: A Prospective Observational Study
This study will observe patients with lower limb varicose veins who also have knee pain. Many patients with varicose veins experience swelling, heaviness, or aching in the legs, and some also report pain in or around the knee.
- Conditions
- Varicose Veins of Lower Limb, Chronic Venous Insufficiency, CVI, Knee Pain Chronic, Knee Osteoarthritis
- Trial name
- VV-KNEE (NCT07163312)
- Testing
- Endovenous Ablation for Varicose Veins
- Volunteers
- 50 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Phantom Pain Following Amputation of Lower Limb, Amputation
Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain.Home-Based Treatment
After amputation of an arm or leg, up to 90% of subjects experience a "phantom limb", a phenomenon characterized by persistent feelings of the missing limb.
- Trial name
- PLP Home-Based (NCT07044323)
- Testing
- Active Virtual Reality Treatment
- Where
- 3 sites in United States
- Volunteers
- 44 people
- Sponsor
- Albert Einstein Healthcare Network
Lymphedema, Lower Limb
Correlation Between Volume and Pain in Lower Limbs Lymphoedema
The vascular physiotherapy department of the UCL University Clinics of Mont-Godinne specializes in the physiotherapeutic management of lymphoedema.
- Trial name
- NCT06145204
- Testing
- questionnaire
- Where
- Belgium
- Volunteers
- 79 people
- Sponsor
- University Hospital of Mont-Godinne
Lower Limb Deformity, Anterior Knee Pain Syndrome
Is Gait Analysis for Proposed Rotational Deformities a Useful Resource
Rotational deformities, such as femoral (thigh bone) and tibial (leg bone) torsion, are established causes of patellofemoral (kneecap joint) pain and instability.
- Conditions
- Lower Limb Deformity, Anterior Knee Pain Syndrome, Patellofemoral Pain, Rotation; Deformity
- Trial name
- NCT05576064
- Testing
- Gait analysis
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Greater Trochanteric Pain Syndrome of Both Lower Limbs, Gluteal Tendinitis
Reliability, Validity, and Cross-cultural Adaptation of the Turkish Version of the Victorian Institute of Sports Assessment for Gluteal Tendinopathy (VISA-G) Questionnaire
The purpose of this study was to investigate adaptation, validity, and reliability of the Turkish version of the Victorian Institute of Sports Assessment for Gluteal Tendinopathy (VISA-G) Questionnaire.
- Trial name
- NCT04707274
- Testing
- Survey study
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Gazi University
Phantom Limb Pain, Phantom Pain
VR to Evaluate Phantom Limb Pain
The objective of this study is to develop a virtual rehabilitation system that can be used to effectively treat Phantom Limb Pain (PLP) within the research setting and for at-home use by individuals with upper and lower extremity…
- Conditions
- Phantom Limb Pain, Phantom Pain, Phantom Sensation, Phantom Limb Syndrome With Pain
- Trial name
- NCT05915065
- Testing
- Coapt Phantom Limb Pain Management System
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Shirley Ryan AbilityLab
Pelvic Varices, Varicose Veins of Lower Limb
Study of Venous Outflow From the Lower Limbs in Patients With Pelvic Varicosities
Compression therapy is basic treatment for chronic venous disease (CVD) of the lower limbs. Numerous studies have demonstrated the efficacy and safety of compression therapy in relieving symptoms such as pain, venous edema, leg…
- Conditions
- Pelvic Varices, Varicose Veins of Lower Limb, Pelvic Pain Syndrome, Pelvic Congestive Syndrome
- Trial name
- NCT06124664
- Testing
- Radionuclide venography, single-photon emission computed tomography
- Where
- Russia
- Volunteers
- 90 people
- Sponsor
- Pirogov Russian National Research Medical University
Foot Deformities, Pes Planus
The Relationship of the Medial Longitudinal Arch Height With Clinical Features of Knee Osteoarthritis
The goal of this observational study is to investigate the relationships between the medial longitudinal arch (MLA) height of the foot and clinical and radiological characteristics of knee osteoarthritis in adult patients 50 aged…
- Conditions
- Foot Deformities, Pes Planus, Pes Cavus, Knee Osteoarthritis
- Trial name
- NCT05656014
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Gazi University
Chronic Lower Limb Pain
Basic Assessment of Safety and Minimally Invasive Stimulation Via Injectrode
The objectives of this non-significant risk (NSR) study are to evaluate the safety of the short term placement of the Basmati Injectrode for up to 28 days and the efficacy of conducting electrical current to stimulate…
- Trial name
- BASMATI (NCT04672096)
- Testing
- Neuronoff BASMATI Injectrode
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Neuronoff, Inc
Epidural, Oxycodone
Epidural Oxycodone for Pain Management for Lower Limb Amputation
The aim of this study is to evaluate the effect of epidural oxycodone for pain management after lower limb amputation.
- Conditions
- Epidural, Oxycodone, Pain, Lower Limb Amputation
- Trial name
- NCT06276179
- Testing
- Oxycodone, Bupivacaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kafrelsheikh University
Phantom Pain Following Amputation of Lower Limb
the Influence of Virtual Reality Approach on Phantom Pain in Trans Tibial Amputation
1. To investigate the effect of Virtual reality (VR) on phantom limb pain in trans tibial amputation. 2. To investigate the effect of Virtual reality (VR) on lower limb Function in trans tibial amputation.
- Trial name
- NCT06262503
- Testing
- Virtual Reality, Transcutaneous Electrical Nerve Stimulation (TENS), Mirroring Therapy
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Greater Trochanteric Pain Syndrome of Both Lower Limbs
Shock Wave Therapy Plus Exercise in GTPS
The aim of this randomized controlled study is to investigate if the sequential administration of focused shock wave therapy and of a rehabilitation program based on the strengthening of gluteal muscles is more effective than a…
- Trial name
- GTPSSWEX (NCT06248905)
- Testing
- Rehabilitation program based on the strengthening of gluteal muscles, Extracorporeal shock wave therapy
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Phantom Limb Pain, Phantom Pain
Study of Lower-limb Phantom Pain Syndrome Using Peripheral Nerve and Spinal Cord Stimulation
Brief Summary: The purpose of this study is to evaluate the effectiveness of neuromodulation for relief of phantom limb pain (PLP) using peripheral nerve (PNS) and spinal cord (SCS) stimulation with implantable electrodes.
- Conditions
- Phantom Limb Pain, Phantom Pain, Amputation, Lower Limb Amputation
- Trial name
- NCT05807607
- Testing
- Implantation of PNS electrodes during surgery, mapping to select sites with the best effect and daily modulation., SCS electrode implantation at surgery, mapping to select sites with the best effect and pain modulation, Change according to the scale of the PainDetect questionnaire
- Where
- Russia
- Volunteers
- 10 people
- Sponsor
- Artur Biktimirov
Chronic Pain, Low Back Pain
A Prospective, Multi-site, Randomized, Sham-Controlled, Double-Blind Trial With One-Way Crossover Designed to Assess the Effectiveness and Safety of the Gimer NeuroBlock SCS Trialing System for the Treatment of Chronic Back Pain and/or Lower Limb Pain
This study is a prospective, multi-site, randomized, shamcontrolled, double-blind trial with one-way crossover designed to assess the effectiveness and safety of the Gimer NeuroBlock SCS Trialing System for the treatment of…
- Conditions
- Chronic Pain, Low Back Pain, Lower Limb Pain
- Trial name
- NCT04693650
- Testing
- NeuroBlock UHF stimulation
- Where
- 4 sites in Taiwan
- Volunteers
- 22 people
- Sponsor
- GiMer Medical
Postoperative Pain, Lower Limb Injury
Block Duration After Spinal Block and iv Dexamethasone.
It has been largely demonstrated that iv dexamethasone prolongs the duration of analgesia after peripheral nerve block. However, data are missing regarding the duration of analgesia after spinal block.
- Trial name
- NCT03527576
- Testing
- Dexamethasone, NaCl 0.0308 MEQ/ML Injectable Solution
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Eric Albrecht
Muscle Injury, Lower Limb Injury
Effects of ART® on Lower Limb Myofascial Pain and Function
This is a feasibility study to determine if the investigators can conduct a clinical trial with a sham and control soft tissue treatment.
- Trial name
- NCT04535635
- Testing
- Active Release Techniques®
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Canadian Memorial Chiropractic College
Postoperative Pain, Peripheral Neuropathy
Duration of Blockade of Peripheral Nerves With Bupivacaine Depending of the Adjuvants
The main aim of the investigator's study is to propose combination of local anesthetics and adjuvants that provides both adequate anesthesia during surgery and prolonged post-operative analgesia.
- Conditions
- Postoperative Pain, Peripheral Neuropathy, Fractures of the Upper Limb, Fracture of the Lower Limb (Except Hip), Initial Encounter
- Trial name
- DBBA (NCT04498923)
- Testing
- Bupivacaine, dexamethasone, epinephrine
- Where
- Ukraine
- Volunteers
- 68 people
- Sponsor
- Lviv National Medical University
Traumatic Amputation of Lower Extremity, Phantom Limb Pain
Spinal Root and Spinal Cord Stimulation for Restoration of Function in Lower-Limb Amputees
The goals of this study are to provide sensory information to amputees and reduce phantom limb pain via electrical stimulation of the lumbar spinal cord and spinal nerves.
- Trial name
- SCS-LL (NCT03027947)
- Testing
- Spinal cord stimulator
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Pittsburgh
Chronic, Intractable Pain of the Trunk and/or Lower Limbs
Evaluating Anatomic Versus Targeted Lead Placement for Burst Stimulation Therapy During the Trial
Prospective, multi-center, randomized, single blind study
- Trial name
- DELIVERY (NCT03277378)
- Testing
- lead placement followed by BurstDR stimulation
- Where
- 25 sites in United States, Australia and 5 more
- Volunteers
- 270 people
- Sponsor
- Abbott Medical Devices
Chronic Lower Limb Pain
A Safety and Effectiveness Trial of Spinal Cord Stimulation of the Dorsal Root Ganglion for Chronic Lower Limb Pain
The purpose of this study is to evaluate the safety and effectiveness of the AXIUM Neurostimulator System for the treatment of chronic lower limb pain in persons diagnosed with Complex Regional Pain Syndrome (CRPS) or Peripheral…
- Trial name
- ACCURATE (NCT01923285)
- Testing
- AXIUM Neurostimulator System, Control Spinal Cord Stimulation Device
- Where
- 22 sites in United States
- Volunteers
- 152 people
- Sponsor
- Abbott Medical Devices