Clinical trials: Lower Limb Trauma
Femoral Neck Fracture
Influence of the Spatial Distribution of Hollow Screws on the Blood Supply and Prognosis of Femoral Neck Fractures
Femoral neck fracture is a common type of fracture in the elderly. For those without significant displacement (Garden I, II), more hip-preserving treatment strategies are adopted.
- Trial name
- NCT05171140
- Testing
- Triangular Nail Placement of Femoral Neck
- Where
- China
- Volunteers
- 68 people
- Sponsor
- RenJi Hospital
Motor Disorders, Gait Disorders, Neurologic
Adherence to Long-term Exoskeleton Rehabilitation to Treat Lower Limb Weakness and / or Deficiencies in Adult Population
In 2019, approximately 2.4 billion people worldwide required rehabilitation for various health pathologies, a 63% increase since 1990.
- Conditions
- Motor Disorders, Gait Disorders, Neurologic, Neurodegenerative Diseases, Spinal Cord Injuries
- Trial name
- ALERT (NCT06538974)
- Testing
- Hands-free exoskeleton
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Wandercraft
Ankle Injuries
Neurophysiology of Ankle Instability
Chronic ankle instability (CAI) is a common debilitating orthopedic condition that disrupts physical function and decreases quality of life. Not all CAI is the same.
- Trial name
- NCT06576687
- Testing
- Physical Rehabilitation
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Diabetic Foot Ulcer
Fluorescence Image-Guided Healing Trial
Lower extremity complications such as chronic diabetic foot ulcers (DFUs) are a major risk for Type I/II diabetes patients. Minor injuries that would normally heal without consequence in non-diabetic individuals are at greater…
- Trial name
- FLIGHT (NCT04163055)
- Testing
- Moleculight i:X
- Volunteers
- 294 people
- Sponsor
- University Health Network, Toronto
Hip Fractures
Clinical Outcomes of Analgesia Methods in Patients With Hip Fracture
The goal of this study is to determine of clinical outcomes of analgesia methods. The primary outcomes are opioid consumption, static and dynamic visual analog scale (VAS) scores. Secondary outcomes are occurrence of side effects.
- Trial name
- NCT03670290
- Testing
- Fascia iliaca compartment catheter, epidural catheter, patient controlled analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Mersin University
Anterior Cruciate Ligament Injuries
Prognosis Study of Different Anterior Cruciate Ligament Surgery Methods
From June 1, 2016, to July 1, 2017, a total of 406 patients with ACL rupture were randomly assigned to three different ACL surgeries: anatomical single-bundle, central axial single-bundle and double-bundle.
- Trial name
- ACLRSurgRCT (NCT05400460)
- Testing
- Anatomical single-bundle reconstruction（ASBR method）, Double-bundle reconstruction （DBR method）, Central axial single-bundle reconstruction（CASBR group）
- Volunteers
- 406 people
- Sponsor
- Yu Jiakuo
Stroke, Spinal Cord Injuries (SCI)
ZEPU-AI1 Gait Robot Training Study (ZEPUAI1RCT)
Walking problems caused by stroke, spinal cord injury, or orthopedic surgery are common and can seriously limit a person's independence.
- Conditions
- Stroke, Spinal Cord Injuries (SCI), Gait Disorders, Neurologic
- Trial name
- NCT07735676
- Testing
- ZEPU-AI1 Gait Training and Evaluation System, Standard-of-Care Rehabilitation (Individualized Rehabilitation and Exercise)
- Where
- Bangladesh
- Volunteers
- 51 people
- Sponsor
- Bangladesh Medical University
Compartment Syndrome
Continuous Pressure Monitoring In Lower Leg Fractures
This study has been designed to allow us to learn more about diagnosing Compartment Syndrome, which is a condition that occurs in approximately 5% of tibial (lower leg) fractures.
- Trial name
- NCT00358514
- Testing
- Continuous Compartment Pressure Monitoring
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- University of British Columbia
Venous Leg Ulcer, Social Interaction
The Impact of Frequenting a Social Leg Program on Therapeutic Adherence and Venous Leg Ulcer Wound Healing Outcomes
Background and rationale: Venous leg ulcers (VLU) are slow healing wounds with a recurrence rate up to 70% and a 60% risk of becoming chronic.
- Trial name
- legclub (NCT04370106)
- Testing
- Social leg program
- Where
- 2 sites in Switzerland
- Volunteers
- 268 people
- Sponsor
- School of Health Sciences Geneva
Rupture of Anterior Cruciate Ligament
Multicenter ACL Revision Study (MARS)
The purpose of this study is to determine the effects of modifiable risk factors on patient-reported quality of life, physical activity levels, and risk of early osteoarthritis following revision anterior cruciate ligament (ACL)…
- Trial name
- MARS (NCT00625885)
- Where
- 49 sites in United States, Canada
- Volunteers
- 1,234 people
- Sponsor
- Vanderbilt University Medical Center
Ankle Fracture
Exparel and Ankle Surgery
This study involves a drug called Exparel that has been approved by the US Food and Drug Administration (FDA), for application directly to wound sites. EXPAREL® is a long acting pain reliever.
- Trial name
- NCT02072135
- Testing
- Exparel
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Rutgers, The State University of New Jersey
Hip Fracture, Geriatrics
Clinical Efficacy of Exoskeleton Robot-Assisted Rehabilitation on Lower Limb Functional Recovery in Elderly Patients With Hip Fracture
With the intensification of population aging, hip fracture, as a common bone disease, is seeing an increasing incidence rate among the elderly population.
- Conditions
- Hip Fracture, Geriatrics, Lower Extremity Dysfunction, Postoperative Rehabilitation
- Trial name
- NCT07323147
- Testing
- Exoskeleton, Conventional rehabilitation program
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Hai bao
Hip Fractures (ICD-10 72.01-72.2)
Risk Early Warning Management for Postoperative Hip Fracture Rehabilitation and Delirium Prevention in Elderly Patients
This clinical study aims to evaluate the effectiveness of a perioperative risk early warning management strategy in patients undergoing surgical treatment for hip fractures.
- Trial name
- NCT06966947
- Testing
- Risk Early Warning Management, Standard Perioperative Care
- Where
- China
- Volunteers
- 284 people
- Sponsor
- People's Hospital Affiliated to Hubei University of Medicine
Ankle Injuries, Syndesmotic Injuries
Grappler Interference Screw Post-Market Collection of Patient Reported Outcome Measures
Ambispective, multi-surgeon, single site, consecutive case series to determine the safety, performance, and benefits of the Grappler(R) Interference Screw.
- Conditions
- Ankle Injuries, Syndesmotic Injuries, Ankle Inversion Sprain, Deltoid Ankle Sprain
- Trial name
- NCT05190874
- Testing
- Grappler Interference Screw System
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Paragon 28
Hallux Limitus, Movement, Abnormal
Foot Posture Index, Hallux Limitus in Patients With Chronic Low Back Pain. Gait With Optogait Sensor
Foot disorders have been recognized as being linked to chronic low back pain
- Conditions
- Hallux Limitus, Movement, Abnormal, Back Pain Lower Back Chronic
- Trial name
- NCT04607863
- Testing
- Case control
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Seville
Hip Fractures
Effect of Pericapsular Nerve Group (PENG) Block for Perioperative Analgesia in Geriatric Patients With Hip Fractures
the goal of this clinical trial is to evaluate the analgesic effect of pericapsular nerve group (PENG) block in elderly patients with hip fractures undergoing hip surgery .
- Trial name
- NCT05941221
- Testing
- pericapsular nerve group (PENG) block
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Ain Shams University
Iliotibial Band Syndrome, Pain
Effects of Functional Motor Control on Pain, Flexibility, Lower Extremity Function With ITBS
The study is randomized and single-blinded. Ethical approval is taken from ethical committee of Riphah International University, Lahore.
- Conditions
- Iliotibial Band Syndrome, Pain, Flexibility
- Trial name
- NCT06131658
- Testing
- Functional motor control excercise, convectional excercise
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Ankle Fracture, Trimalleolar, Ankle Fracture - Lateral Malleolus
Operative Treatment of Ankle Fractures
Patients who underwent operative treatment of an ankle fracture with or without following removal of the osteosynthetic material are examined by a specific ankle provocation test, a questionnaire and X-Rays to evaluate the…
- Conditions
- Ankle Fracture, Trimalleolar, Ankle Fracture - Lateral Malleolus, Ankle Fracture, Bimalleolar
- Trial name
- NCT04437355
- Testing
- Specific provocation test
- Where
- Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Spital Limmattal Schlieren
Ankle Fractures, Trauma Injury
Effect of Toradol on Post-operative Foot and Ankle Healing
The use of Toradol for pain control in surgical orthopedic cases is currently a topic of interest within the field. The proposed study is a prospective randomized study evaluating postoperative pain, opioid requirement…
- Trial name
- NCT03727048
- Testing
- Ketorolac, No ketorolac
- Volunteers
- 128 people
- Sponsor
- Rothman Institute Orthopaedics
Ankle Fracture, Ankle Arthrodesis
Compression Therapy for Swelling Management Following Ankle Injury
After an injury or undergoing foot/ankle surgery, patients often experience swelling in the injured area. Under current standard of care, plaster casts are removed at six weeks and patients are put in a walking boot.
- Trial name
- NCT06772649
- Testing
- Compression sleeve
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority