Clinical trials: Lower Urinary Track Symptoms
Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms
Effectiveness of onaBoNT-A vs Oral Tamsulosin in Men With BPH and LUTS
Benign prostatic hyperplasia (BPH) and its related symptoms are a common condition that affects nearly half of men over age 50 and 90% of men over 80.
- Trial name
- NCT01589263
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- VA Office of Research and Development
Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms
Long Term Follow up of Water Vapor Thermal Therapy (Rezum) for Benign Prostatic Hyperplasia (BPH)
This study aims to assess the effectiveness and morbidity of water vapor thermal therapy (Rezūm therapy) for benign prostatic hyperplasia (BPH).
- Trial name
- NCT05982444
- Testing
- water vapor thermal therapy (Rezum) for prostate
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Helwan University
Benign Prostatic Hyperplasia
A Clinical Trial Comparing Laser TURP With and Without Dutasteride.
The purpose of this research study is to determine if the study drug Dutasteride taken before and after Laser TURP(Transurethral Resection of the Prostate), can provide effective and safe, long term improvement of lower urinary…
- Trial name
- NCT00431626
- Testing
- Dutasteride (Avodart)
- Volunteers
- 4 people
- Sponsor
- Northwestern University
Lower Urinary Track Symptoms
Urinary CA19-9 Level in the Differential Diagnosis of Neurogenic and Non-Neurogenic Lower Urinary Tract Dysfunction in Children
It has been shown in the literature that urinary CA19-9 levels are associated with the degree of hydronephrosis and the anteroposterior diameter of the renal pelvis.
- Trial name
- NCT06785545
- Testing
- CA19-9
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lower Urinary Track Symptoms, Urodynamic Exam
e-Sense® Normal Values of Urodynamic Pressures Using e-Sense® Catheters
In this post-market observational study, subjects referred to urodynamic testing will be approached to enroll in a clinical study to define the normal range of pressure values utilizing e-Sense® catheters.
- Trial name
- ESNS-01 (NCT06905808)
- Testing
- eSense 7Fr Single Sensor Bladder Catheter
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Laborie Medical Technologies Inc.
SGLT2 Inhibitors, Lower Urinary Track Symptoms
SGLT-2 Inhibitors and Lower Urinary Tract Symptoms
This prospective observational study aims to evaluate the effects of sodium-glucose cotransporter 2 (SGLT-2) inhibitors on lower urinary tract symptoms (LUTS) in patients with type 2 diabetes mellitus.
- Conditions
- SGLT2 Inhibitors, Lower Urinary Track Symptoms, Overactive Bladder
- Trial name
- NCT07716774
- Testing
- No Intervention: Observational Cohort
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lower Urinary Track Symptoms, Benign Prostate Obstruction (BPO)
Outcome and Patient Experiences After Transurethral Resection and Bipolar Enucleation of the Prostate - a Multi-center, Randomized Controlled Trial.
In this randomized controlled trial, we will evaluate if bipolar enucleation of the prostate (BEEP) is associated with better urinary voiding outcome than transurethral resection (TURP) in men with enlarged prostate referred to…
- Trial name
- NCT07562386
- Testing
- Transurethral resection of the prostate., Bipolar enucleation of the prostate
- Where
- 2 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Sykehuset Innlandet HF
Lower Urinary Track Symptoms, Multiple Sclerosis
Turkish Validity and Reliability of the Core Lower Urinary Tract Symptoms Questionnaire in Individuals With Multiple Sclerosis
The aim of this study is to study the validity and reliability of Core Lower Urinary Tract Symptoms Score in patients with multiple sclerosis.
- Trial name
- NCT06599866
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people
- Sponsor
- Kutahya Health Sciences University
Duchenne Muscular Dystrophy (DMD), Lower Urinary Track Symptoms
Effects of Lumbopelvic Stabilization-based Physiotherapy and Rehabilitation Training in Duchenne Muscular Dystrophy
This study aims to examine the effectiveness of supervised lumbopelvic stabilization in relation to factors associated with lower urinary tract symptoms in children diagnosed with Duchenne Muscular Dystrophy (DMD) who have lower…
- Trial name
- NCT06643923
- Testing
- Exercise, Urotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Lokman Hekim University
Urinary Incontinence
Effects of a Multimodal and Multidimensional Intervention on Urinary Incontinence in Young Nulliparous Female Athletes.
A prevalence of urinary incontinence ranging from 5.7% to 80% has been observed in young nulliparous athletes during their activity. The usual recommendations for managing adult women do not seem to be transferable.
- Trial name
- PELVICATHLE (NCT07644273)
- Testing
- Combined pelvic health education and lumbar-pelvic-abdominal stability strengthening programme., Usual activities
- Where
- France
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms
Ejaculation-Preserving Versus Conventional Dual Wavelength Diode Laser Vaporization of the Prostate
Surgery to relieve urinary blockage caused by an enlarged prostate works well, but most men lose antegrade ejaculation afterwards, because semen passes backwards into the bladder instead of forwards.
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms, Bladder Outlet Obstruction
- Trial name
- EP-TUVP (NCT07777068)
- Testing
- Conventional dual-wavelength diode laser vaporization of the prostate, Ejaculation-preserving dual wavelength diode laser vaporization of the prostate
- Where
- Iraq
- Volunteers
- 119 people
- Sponsor
- ALI KAMAL M. SAMI
Multiple Sclerosis, Lower Urinary Tract Symptoms
Effectiveness of TTNS in MS Patients With Lower Urinary Track Symptoms
Multiple sclerosis (MS) is the most common inflammatory disease of the central nervous system. It is characterized with demyelinated plaques affecting subcortical, brain stem, and spinal cord nerve fibers.
- Trial name
- NCT06263556
- Testing
- Pelvic floor exercises, Transcutaneous posterior tibial nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Bladder, Lower Urinary Track Symptoms
Low-Energy Shock Wave Therapy for Overactive Bladder in Women With Metabolic Syndrome
Overactive bladder (OAB) is a common condition that causes urinary urgency, frequent urination, and nocturia, which can significantly affect quality of life.
- Conditions
- Bladder, Lower Urinary Track Symptoms, Metabolic Syndrome, Urgency-Frequency
- Trial name
- NCT07563764
- Testing
- Low-Energy Extracorporeal Shock Wave Therapy (LiESWT)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- KMUHIRB-F(I)-20230051
Localized Prostate Carcinoma, Prostate Cancer (Adenocarcinoma)
Online Adaptive Stereotactic Body Radiotherapy for Localized Prostate Cancer
The aim of this phase II international multicenter study is to evaluate the safety, feasibility, and efficacy of CT or MRI-adaptive SBRT, delivered in five weekly fractions, in patients with newly diagnosed localized prostate…
- Conditions
- Localized Prostate Carcinoma, Prostate Cancer (Adenocarcinoma), Prostate Hyperplasia, Lower Urinary Track Symptoms
- Trial name
- X-SMILE (NCT06834152)
- Testing
- radiotherapy
- Where
- 3 sites in Germany, Switzerland
- Volunteers
- 75 people
- Sponsor
- University of Zurich
Neurogenic Bladder Disorder, Spinal Cord Injury
Turkish Version of the Neurogenic Bladder Symptom Score Short Form
This observational study aims to evaluate the cross-cultural adaptation and psychometric properties of the Turkish version of the Neurogenic Bladder Symptom Score Short Form (NBSS-SF) in adults with spinal cord injury or multiple…
- Conditions
- Neurogenic Bladder Disorder, Spinal Cord Injury, Multiple Sclerosis, Lower Urinary Track Symptoms
- Trial name
- NCT07507331
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Gaziantep Islam Science and Technology University
BPH (Benign Prostatic Hyperplasia), Lower Urinary Track Symptoms
New Treatment Strategies and Epigenetic Biomarker for Management of Benign Prostatic Hyperplasia
SRD5A2 is a critical enzyme for prostatic development and growth, and the SRD5A2 inhibitor, finasteride, is used to treat benign prostatic hyperplasia (BPH).
- Trial name
- NCT06944145
- Testing
- raloxifene, Finasteride
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Beth Israel Deaconess Medical Center
Benign Prostatic Hypertrophy (BPH), Lower Urinary Track Symptoms
Intradetrusor Onabotulinumtoxin A (Botox) at the Time of Transurethral Resection of the Prostate or Transurethral Waterjet Ablation of the Prostate for Mixed Lower Urinary Tract Symptoms
Patients with longstanding obstructive lower urinary tract symptoms (LUTS) due to benign prostatic hypertrophy (BPH) can also develop symptoms of overactive bladder syndrome (OAB).
- Trial name
- NCT07377929
- Testing
- Survey using a questionnaire.
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Benaroya Research Institute
Benign Prostatic Hyperplasia (BPH), Lower Urinary Track Symptoms
Evaluation of the Optilume BPH Catheter System and the Rezum Water Vapor Therapy in Treating Benign Prostatic Hyperplasia
Lower urinary symptoms (LUTS) affect older men and their frequency and severity increase with age. According to Berry et al., the histological diagnosis of benign prostatic hyperplasia (BPH) increases from 25% in the group age…
- Trial name
- OptiZum (NCT06769997)
- Testing
- Optilume® BPH Catheter System, Rezum Water Vapor Therapy
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Multiple Sclerosis, Lower Urinary Track Symptoms
Silodosin for Urinary Symptoms in Female Patients With Multiple Sclerosis
The goal of this clinical trial is to learn if silodosin works to treat lower urinary tract symptoms (LUTS) in female patients with multiple sclerosis (MS). It will also learn about the effect of the drug on voiding parameters.
- Trial name
- NCT07614321
- Testing
- Silodosin 8 mg
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Atlantic Health System
Benign Prostate Hypertrophy(BPH), Lower Urinary Track Symptoms
Comparison of Holmium Laser Enucleation of the Prostate and Robotic Water Jet Ablation for Benign Prostatic Hyperplasia
This study compares two FDA-approved surgical treatments for benign prostatic hyperplasia (BPH): Holmium Laser Enucleation of the Prostate (HoLEP) with MOSES 2.0 technology and Robotic Water Jet Ablation (RWJA) using the Hydros…
- Trial name
- NCT07772232
- Testing
- Device - HoLEP with MOSES 2.0, RWJA with Hydros Robotic System
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Methodist Hospital Research Institute