Clinical trials: Lumbar
Lumbar Spine Surgery
Lumoptik BRIGHTPOINT Reflectometer Device for Lumbar Epidural Placement
The goal of this clinical trial is to test the BrightPoint Epidural device as the first system to use multispectral reflectometry to find the epidural space in lumbar neuraxial procedures requiring epidural needle.
- Trial name
- NCT06020508
- Testing
- Group 1 - Lumoptik BrightPoint Epidural Device
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Dexmedetomidine VS Fentanyl as Adjuvants to Epidural Bupivacaine in Patients Undergoing Lumbar Spine Surgeries
Evaluation of the Analgesic Effect of Dexmedetomidine Versus Fentanyl as Adjuvants to Epidural Bupivacaine in Patients Undergoing Lumbar Spine Surgeries
To determine if the epidural route provide an acceptable analgesia in spine surgeries and avoided the need for excessive IV analgesics.
- Trial name
- NCT03463083
- Testing
- Dexmedetomidine, Bupivacaine, Fentanyl
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Low Back Pain, Healthy
Analysis of Crepitus in Human Subjects
Chiropractic adjustment has been shown to gap certain joints in the spine, thereby improving mobility in individuals with decreased movement capabilities.
- Trial name
- CrUS (NCT05425017)
- Testing
- Range of motion with spinal adjustment
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National University of Health Sciences
Intraoperative Bleeding
Comparison Between Atenolol,Propnalol and Ivabradine
The aim of this work is to compare atenolol, propranolol, and ivabradine as a premedication to achieve bloodless field anesthesia primarily controlling heart rate in lumbar spine surgery.
- Trial name
- NCT06670690
- Testing
- Atenolol 50 MG, Propranolol Pill, Ivabradine
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Obesity, Morbid, Labor Pain
LOTUS Trial: Lumbar Ultrasound in Obstetric Patients With BMI > 40
The goal of this clinical trial is to compare traditional palpation to pre-procedural lumbar ultrasound prior to epidural placement in obese (BMI >40) obstetric patient population.
- Trial name
- LOTUS (NCT06305260)
- Testing
- Lumbar Ultrasound
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Lumbar Disc Disease
NOCISCAN-Lumbar Spine (LS) Clinical Evaluation Study
A prospective, double blinded, multi-center study to assess the validity and clinical utility of the pre-operative NOCISCAN-LS software in the identification of painful lumbar discs, and the correlation with improved surgical…
- Trial name
- NCT04015791
- Testing
- NOCISCAN-LS Disc MR Spectroscopy
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Nocimed, LLC
Low Back Pain
Comparison of the Stiffness of the Lumbar Back Muscles Between Low Back Pain and Healthy Controls
Chronic low back pain remains a major public health issue. Low back pain is frequently associated with stiffness changes of the lumbar back muscles.
- Trial name
- PARA-ELASTO (NCT03750474)
- Testing
- magnetic resonance elastography and shear wave elastography
- Where
- France
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hamstring Tightness
Effects of Lumbosacral Mobility Program on Tight Hamstrings
The study will be randomized controlled trial to determine the effects of lumbosacral mobility program on muscle length in sedentary young adults with tight hamstrings.
- Trial name
- NCT05393960
- Testing
- Lumbosacral manual therapy mobilization, lumber mobility exercises and home based self strechings program., home based self strechings program only.
- Where
- Pakistan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pain
Video/Audio Distraction Analgesia for Simulated Oncology Procedure Pain
The purpose of this study is to compare the analgesic efficacy of three different types of video/audio distraction in normal volunteers subjected to carefully controlled and non-injurious thermal pain delivered to the skin of the…
- Trial name
- NCT00701571
- Testing
- Virtual Reality distraction
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Washington
Degenerative Lumbar Spondylolisthesis
Degenerative Spondylolisthesis; Micro-decompression vs Decompression + Instrumented Fusion; Long Term Follow up
In many countries a majority of patients with degenerative spondylolisthesis are operated on with decompression plus instrumented fusion, but the scientific evidence for adding fusion is controversial.
- Trial name
- DS-registry (NCT03469791)
- Testing
- Surgical treatment of Degenerative Spondylolisthesis
- Where
- Norway
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Isthmic Spondylolisthesis
Relationship Between Spinopelvic Parameters and Clinical Symptoms of Low-grade Lumbar Isthmic Spondylolisthesis
This was a retrospective study.PI and LL greatly influence IS and its progression. However, relationships between the spinopelvic parameters and clinical symptoms of patients with IS were not fully investigated in previous…
- Trial name
- NCT04968626
- Testing
- PI-LL
- Where
- China
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Erector Spina Plan Block
The Effect of bılateral Erector spına Plan Block on postoperatıve paın ın spınal Surgery
Patients undergoing lumbar spinal stabilization surgery may experience severe postoperative pain lasting at least three days. Analgesia after lumbar stabilization surgery is beneficial for early recovery and is therefore…
- Trial name
- ESPB (NCT07537647)
- Testing
- UNDER ULTRASOUND GUİDANCE ESPB BLOCK, PROCEDURE/SURGERY: ERECTOR SPİNAE (ESP) BLOCK WİTH BUPİVACAİNE
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
The Lumbar Spine Surgical Intervention, Arthrodesis
Evaluation of the Effect of Reiki on Pain After Lumbar Surgery
The goal of this clinical trial (prospective, comparative, and randomized double-blind study) is to learn if Reiki (a non-pharmacological intervention), when used alongside standard care, can treat and reduce postoperative pain…
- Conditions
- The Lumbar Spine Surgical Intervention, Arthrodesis, Severe Herniated Disc, Scoliosis
- Trial name
- REDAL (NCT07722117)
- Testing
- Reiki treatment and chirurgy
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinique Bizet
Spondylolisthesis, Lumbar Region
Midline Versus Paramedian Approaches in Treating Degenerative Lumbar Spondylolisthesis
For the increasing numbers of patients undergoing fusion procedures for the degenerative lumbar spine, infection and re-operation can negatively impact outcomes.
- Trial name
- NCT03344484
- Testing
- Surgical approach
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Abdominal Muscle, Posture
The Effect Thoracolumbar Fascia on the Abdominal Muscle
The aim of this study was to evaluate the changes in the thickness of abdominal muscles during activation of thoracolumbar fascia through contracting the gluteus maximus and latissimus dorsi muscles.
- Conditions
- Abdominal Muscle, Posture, Muscle Strength
- Trial name
- NCT04113642
- Testing
- ultrasonographic measurement of abdominal muscle thickness at four positions
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Koç University
Spinal Manipulation, Chiropractic
Comparison of the Effectiveness of Chiropractic Manipulation Applied to the Lumbar Sacroiliac Region in Patients With Lumbar Disc Herniation
This study aims to compare the effectiveness of chiropractic manipulation applied to the lumbar and sacroiliac regions in patients with lumbar disc herniation.
- Conditions
- Spinal Manipulation, Chiropractic, Lumbal Disc Herniation
- Trial name
- CLuSH (NCT07037641)
- Testing
- Lumbar Spine Manipulation, Sacroiliac Joint Manipulation, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK
Low Back Pain, Chronic Low Back Pain
From Structural to Functional Characteristics of the Lumbar Multifidus in Low Back Pain
To delineate the underlying mechanisms that contribute to chronic low back pain, by extending our knowledge on structural characteristics of the lumbar multifidus muscle using ultrasound muscle imaging, and by examining the…
- Trial name
- NCT03612089
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Spine Health, Spine Injuries and Disorders
Occupational Exposure to Whole Body Vibration Among U.S. Military Veterans: Acute and Chronic Contributions to Musculoskeletal Disorders and Spine-Area Pain
Significance to VA: There is a lack of prospective longitudinal studies investigating the relationship between risk factors to Veterans and development and progression of musculoskeletal (MSK) spine injury and pain.
- Conditions
- Spine Health, Spine Injuries and Disorders, Spine Degeneration, Whole Body Vibration
- Trial name
- NCT07367139
- Testing
- Water
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Milwaukee VA Medical Center
Surgical Wound, Herniation
Efficacy of a Full-Thickness Placental Allograft in Lumbar Microdiscectomy
To evaluate the efficacy of full thickness placental allograft use in Microdiscectomy application. To evaluate post-microdiscectomy reherniation rate in patients treated with full-thickness placental allografts.
- Trial name
- NCT03536013
- Testing
- Other: Full-thickness placental allograft
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- StimLabs
Osteoarthritis, Hip
Systemic Steroids for Peripheral Nerve Blocks
This study will investigate the ability of systemic dexamethasone to prolong the sensory block duration for lumbar plexus nerve blockade.
- Trial name
- NCT02464176
- Testing
- Dexamethasone, Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences