Clinical trials: Lumbar Back Pain
Low Back Pain
AlloGen-LI Treatment of Spinal Stenosis
In this pilot study, investigators will test the efficacy of AlloGen-LI, an allograft derived from amniotic fluid, injected into the epidural space at the level of spinal stenosis as an anti-inflammatory treatment to relieve back…
- Trial name
- NCT02932020
- Testing
- AlloGen-LI, depomedrol, MRI
- Where
- United States
- Sponsor
- University of Southern California
Low Back Pain
Effects of Manipulative Therapy and Pain Education in Individuals With CLBP
The burden of low back pain more than doubled in the last 20 years, probably caused by biopsychosocial factors. Some noninvasive treatments have been applied in individuals with chronic nonspecific low back pain as spinal…
- Trial name
- NCT02982382
- Testing
- Manipulative Therapy, Pain Education
- Where
- Brazil
- Volunteers
- 128 people
- Sponsor
- Santa Catarina Federal University
Superior Cluneal Nerve Entrapment, Chronic Low Back Pain
Ultrasound-Guided Proximal Superior Cluneal Nerve Block for Superior Cluneal Nerve Entrapment
Superior cluneal nerve entrapment (SCNE) is an underrecognized cause of chronic low back pain and gluteal pain that may mimic lumbar spine disorders.
- Trial name
- PRO-SCN (NCT07712406)
- Testing
- Ultrasound-Guided Proximal Superior Cluneal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Chronic Low Back Pain
Effects of Motivational Interviewing on Self-Efficacy and Standardized Low Back Pain Outcomes in Patients With Chronic Back Pain"
The majority of the study consists of standard of care treatment for people with low back pain that has lasted more than three months.
- Trial name
- NCT00170118
- Testing
- motivational interviewing
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Low Back Pain
Reliabılıty,Validity Of The Turkish Version Of The Back Pain Function Scale
This study, we performed the Turkish version validity and reliability of the Back Pain Function Scale.
- Trial name
- NCT03175510
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Gazi University
Low Back Pain
The Effectiveness of Aquatherapy on Physical Performance and Fear of Falling in Geriatric Individuals With Low Back Pain
This randomized controlled trial is designed to evaluate the effects of aquatherapy on physical performance, balance, and fear of falling in older adults with chronic low back pain.
- Trial name
- NCT07531017
- Testing
- Aquatherapy, Conservative Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Low Back Pain
Dry Needling Effects on Cortical Excitability
The investigators plan to use a pre-test post-test research design to investigate whether dry needling (DN) has an effect on cortical excitability in patients with chronic low back pain (CLBP), specifically in patients who have…
- Trial name
- NCT05111691
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Texas Woman's University
Low Back Pain, Obesity
The Effect of Traction Forces in People With Obesity Suffering From Chronic Low Back Pain
The purpose of the research study is to assess the impact of traction forces on changes in systemic markers concentrations of spinal structure damage in people with obesity.
- Trial name
- NCT04507074
- Testing
- lumbar traction therapy
- Where
- Poland
- Volunteers
- 49 people
- Sponsor
- Poznan University of Physical Education
Internet-Based Cognitive Behavioral Therapy
Efficacy of Internet-Based Cognitive Behavioral Therapy for Back Muscle Strength Loss, Chronic Pain, and Poor Patient Recovery Perceptions After Lumbar Fusion
This study aims to develop an Internet-based Cognitive Behavioral Therapy protocol for core muscle training, based on an understanding of factors impeding postoperative core muscle training in lumbar surgery patients.
- Trial name
- NCT07030582
- Testing
- Internet-delivered cognitive behavioral therapy, Basic Postoperative Care, Conventional Postoperative Care
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jiawei Jiang
Chronic Low Back Pain (CLBP)
Comparison Between Lumbar Stabilization Exercises and Lumbar Manipulation on Multifidus Muscle in Chronic Low Back Pain This Study Will Investigate and Compare the Effect of Lumbar Stabilization Exercises and Manipulation on Multifidus Muscle in Chronic Low Back Pain
Histological and morphological changes of multifidus muscle have been reported in lumbar disc herniation (LDH), but there is scarce research comparing the efficacy of different treatment programs that can correct multifidus…
- Trial name
- NCT06796023
- Testing
- Stretching and strengthening exercises for back muscles, Lumbar stabilization Exercises, Lumbar Manipulation
- Volunteers
- 60 people
- Sponsor
- Cairo University
Facet Joint Arthrosis, Low Back Pain
Effectiveness of Pain and Exercise Training With Telerehabilitation on Lumbar Facet Joint Arthrosis
The study investigates the effects of pain and exercise training via telerehabilitation method on pain, pain beliefs, trunk mobility, functionality, and quality of life in individuals with low back pain caused by facet joint…
- Trial name
- NCT04981132
- Testing
- Pain Neuroscience education + Progressive therapeutic exercise training, Progressive therapeutic exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Okan University
Musculoskeletal Diseases, Low Back Pain
Front Line Agreement in Diagnosis and Treatment for Musculoskeletal Dysfunctions
Background: This randomized study, conducted from October to December 2023 in the emergency department of Bethesda Hospital Basel, Switzerland, investigated a new model of care for patients presenting with non-urgent…
- Conditions
- Musculoskeletal Diseases, Low Back Pain, Emergency Service, Hospital, Physical Therapy Modalities
- Trial name
- DirectPhysio (NCT07443098)
- Testing
- Intervention: ED - physiotherapist group, Control: resident physician group
- Where
- Switzerland
- Volunteers
- 102 people
- Sponsor
- Bern University of Applied Sciences
Non-specific Low Back Pain, Lumbar Traction
Effects of Different Positions on Mechanical Traction Outcome
Our primary purpose for this study is to investigate the effect of different positions during traction on pain, function, and range of motion in adults with non-specific low back pain.
- Trial name
- NCT06812338
- Testing
- mechanical traction
- Volunteers
- 30 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Chronic Low Back Pain
Sensory Stimulation Belt for Chronic Low Back Pain in Office Workers
This randomized, double-blind, sham-controlled trial will evaluate the effectiveness of a sensory stimulation belt in office workers with chronic nonspecific low back pain.
- Trial name
- LSS-BELT (NCT07801755)
- Testing
- Active Sensory Stimulation Belt
- Where
- Thailand
- Volunteers
- 72 people
- Sponsor
- Mahidol University
Low Back Pain, Thoracic
Investigation of Regional Interdependence of the Hip and Spine in Baseball Players With Low Back Pain
Low back pain (LBP) is a common musculoskeletal symptom in athletes. More than 40% percent of high school baseball players reported incidents of LBP during the previous year.
- Trial name
- NCT06252740
- Testing
- No intervention
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Idiopathic Scoliosis, Pain
Evaluation of Thoracolumbar Fascia and Relationship With Low Back Pain in Individuals With Idiopathic Scoliosis
This observational study seeks to explore the potential association between thoracolumbar fascia characteristics and low back pain in individuals diagnosed with idiopathic scoliosis.
- Trial name
- NCT06055140
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Low Back Pain
Basivertebral Nerve Ablation With the Intracept Procedure
This is an independent prospective, noninterventional, single arm post market data collection of the patient-reported effectiveness, ongoing safety, and satisfaction outcomes for patients treated with intraosseous basivertebral…
- Trial name
- NCT05692440
- Testing
- Intracept Procedure
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Neuro Spine and Pain Center of Key West
Chronic Non-specific Low Back Pain
Comparison of VER-01 to Opioids in Patients With Chronic Non-specific Low Back Pain
Randomized, open-label, parallel-group phase III trial to prove an additional benefit of the full-spectrum cannabis extract VER-01 over opioids in patients with chronic non-specific low back pain for whom drug treatment is…
- Trial name
- ELEVATE (NCT05610813)
- Testing
- VER-01, Opioid therapy
- Where
- 2 sites in Germany
- Volunteers
- 384 people
- Sponsor
- Vertanical GmbH
Low Back Pain, Pain
The Use of Manual Therapy to Treat Low-Back and Hip Pain
Low back pain (LBP) is a common problem in the adult population with many approaches to treatment, but no clear answer. One of the causes of LBP, musculoskeletal pain, can be triggered by spasm of the deep muscles of the back and…
- Trial name
- NCT00410397
- Testing
- Osteopathic Manipulative Medicine
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Oklahoma State University Center for Health Sciences
Low Back Pain
Ibuprofen Plus Metaxolone, Tizanidine, or Baclofen for Low Back Pain
This is a randomized study, based in emergency departments, in which the investigators determine the utility of adding various skeletal muscle relaxants to standard therapy, which consists of ibuprofen and an educational session.
- Trial name
- NCT03068897
- Testing
- Metaxalone, Tizanidine, Baclofen
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- Montefiore Medical Center