Clinical trials: Lumbar Back Pain
Degenerative Disc Disease
Viable Allograft Supplemented Disc Regeneration in the Treatment of Patients With Low Back Pain
The objective of this study is to evaluate the safety and efficacy of viable allograft transplantation for the treatment of patients with symptomatic disc degeneration and tissue loss.
- Trial name
- VAST (NCT03709901)
- Testing
- Active Allograft
- Where
- 13 sites in United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- VIVEX Biologics, Inc.
Low Back Pian
Strain Counter Strain and Muscle Energy Technique in Non-specific Low Back Pain
Low back pain (LBP) is a condition characterized by fatigue, discomfort in the lumbosacral area, and a most common cause of disability .
- Trial name
- NCT07854028
- Testing
- Group A, Group B
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Riphah International University
Beliefs, Disability Physical
Educational Tools to Improve Beliefs About Pain and Reduce Pain-related Disability
This trial aims at comparing the effectiveness of different didactic tools developed for patients with chronic pain to correct misbeliefs and improve disability in patients with chronic low back pain
- Trial name
- NCT03301428
- Testing
- Retrain pain educational website, Booklet
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- University of Liege
Non-specific Chronic Low Back Pain
Relationships Between Muscle Activity, Soft Tissue Changes, and Movement Strategies in Individuals With Chronic Low Back Pain
This study aims to explore, in patients with chronic non-specific low back pain (cnsLBP), the relationships between lumbar muscle activity, structural and morphological characteristics of the paraspinal muscles, and movement…
- Trial name
- E-LBP (NCT07806253)
- Testing
- Supervised Progressive Walking Test
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Low Back Pain, FALS
Postural Control as a Predictor of Disability, Fall-Related Fear, and Social Participation in Elderly Women With Non-Specific Low Back Pain
Non-specific low back pain (NSLBP) is prevalent among elderly women and is often associated with impaired postural control, increased fear of falling, and reduced community participation.
- Trial name
- NCT07170501
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Chronic Low-back Pain
Music-based Treatments and Pain: Underlying Mechanisms and the Beneficial Effects of Music-Based Treatments
The purpose of this study is to understand the mechanisms that underlie the beneficial effects of music-based treatments in individuals with moderate to severe chronic low back pain
- Trial name
- NCT05578781
- Testing
- Music Therapy, Music Medicine, Control group
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Washington
Chronic Non-specific Low Back Pain
Prolotherapy in Acupoints in Chronic Non-specific Low Back Pain (cLBP)
Chronic non-specific low back pain (CNSLBP) is among the most prevalent causes of disability on the planet, which often proves to be refractory to conventional pharmacological, interventional, and rehabilitation approaches.
- Trial name
- NCT07296653
- Testing
- Dextrose 15% and lidocaine 1% infiltration, Lidocaine 1% infiltration
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- National and Kapodistrian University of Athens
Low Back Pain, Aging
Machine-Based Pilates on Quality of Life and Low Back Pain in Older Adults
Chronic low back pain is one of the most prevalent and debilitating conditions among older adults, often compromising physical function and overall quality of life.
- Conditions
- Low Back Pain, Aging, Quality of Life
- Trial name
- Pilates-LBP (NCT07596602)
- Testing
- Machine-Based Classical Pilates Program
- Where
- Portugal
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Instituto Politécnico de Leiria
Low Back Pain
A Study to Evaluate the Effectiveness and Safety of Tapentadol (CG5503) Extended Release (ER) in Patients With Moderate to Severe Chronic Low Back Pain
The purpose of this trial is to evaluate the effectiveness (level of pain control) and safety of orally administrated tapentadol (CG5503) Extended Release (ER) (base) at doses of 100-250 mg twice daily in patients with moderate…
- Trial name
- NCT00449176
- Testing
- tapentadol (CG5503) ER, oxycodone CR
- Volunteers
- 981 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Pain, Acute, Pain, Chronic
Changes in Affective Pain Processing in Human Volunteers
The experience of pain is more than the conscious perception of nociceptive signals. Emotional and motivational aspects accompany pain, leading to its aversiveness and motivation for avoidance.
- Conditions
- Pain, Acute, Pain, Chronic, Low Back Pain
- Trial name
- NCT04280796
- Testing
- psychophysical tasks, cognitive task
- Where
- Switzerland
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- susanne becker
Low Back Pain, Obesity
Resistance Exercise Effects on Fear Avoidance and Physical Function in Obese Older Adults With Low Back Pain
The purpose of this study is to determine if a 4 month resistance exercise program reduces the severity of low back pain, pain-related fear avoidance and improves mobility compared to standard care.
- Trial name
- NCT01250262
- Testing
- normal medical care and follow up, Isolated Lumbar Resistance Exercise Program, Total Body Resistance Exercise Program
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Florida
Low Back Pain
Clinical Observation on the Treatment of Massage Based on Fascia Chain
The goal of thisclinical trial is to observe and quantify the impact of our massage methods on the human body based on B-mode ultrasound, Vas score, and ODI score, and to compare our massage methods with traditional Chinese…
- Trial name
- NCT05974761
- Testing
- massage, Traditional Chinese massage
- Where
- China
- Volunteers
- 76 people
- Sponsor
- muxing zhu
Low Back Pain
Effect of Interferential l Therapy on Low Back Pain
Background: Chronic non-specific low back pain is defined as unknown mechanical musculoskeletal pain lasting more than 3 months.
- Trial name
- [PTREC] (NCT03961477)
- Testing
- Interferential therapy
- Where
- 2 sites in Egypt
- Volunteers
- 61 people
- Sponsor
- Ahlia University
Non Specific Chronic Low Back Pain
Evaluation of Return to Work One Year After a Rehabilitation Program for Chronic Back Pain
Return to work is one of the essential objectives of functional spinal restoration programs. When the duration of the work stoppage increases, the chances of returning to work become worse.
- Trial name
- NCT03936725
- Testing
- 1 year phone call : data collection
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Mechanical Low Back Pain, Lumbopelvic Pain
Effect of Coordinated Locomotor Training on Lumbopelvic Stability and Pain in Runners With Mechanical Low Back Pain
Mechanical low back pain is a common problem among novice runners, often caused by poor control of the lumbopelvic region and weak core stability.
- Trial name
- CLT-LBP-RUN (NCT07604168)
- Testing
- Coordinated Locomotor Training, Plyometric Training
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- University of Faisalabad
Low Back Pain
Effectiveness of the Pilates Method Versus Aerobic Exercises in Elderly With Low Back Pain
Chronic low back pain is potentially disabling for the elderly, and physical exercises are considered the best treatment for this problem.
- Trial name
- NCT02729779
- Testing
- Pilates Group, Aerobic Group
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Universidade Cidade de Sao Paulo
Postpartum Disorder, Lumbar Pain Syndrome
Effects of Assisted Sit-up Exercise vs Swiss Ball Pikes on Postpartum Low Back Pain.
The aim of this study is to evaluate and compare the effectiveness of assisted sit-up exercise and swiss ball pikes on the treatment of pain and disability of postpartum low back pain.
- Conditions
- Postpartum Disorder, Lumbar Pain Syndrome, Activation, Patient
- Trial name
- NCT05355246
- Testing
- assisted sit-up exercises, swiss ball pikes exercises
- Where
- Pakistan
- Volunteers
- 21 people
- Sponsor
- Riphah International University
Lordosis, Low Back Pain
Comparing the Effects of Muscle Energy Technique Versus Myofascial Mobilization in Managing Sub-acute Low Back Pain
Institute for Clinical Systems Improvement (ICSI) defines sub-acute low back pain as low back pain lasting between 4 and 12 weeks.
- Trial name
- NCT05428280
- Testing
- Physiotherapy, Muscle Energy technique, Myofacial mobilization
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Back Pain Lower Back Chronic
A Comparative Study of Erector Spinae Fascia (ESF) Injection and Dry Needling Combined With Functional Rehabilitation (FR) in Patients With Chronic Low Back Pain Who Have Undergone Spinal Surgery (SPIN-NEED)
Chronic low back pain represents a major public health issue, with an estimated prevalence of up to 23% in the adult population and a significant impact on quality of life and functional capacity.
- Trial name
- SPIN-NEED (NCT07555496)
- Testing
- infiltration of the erector spinae fascia, Dry needling
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Clinique de la Côte d'Emeraude
Chronic Low Back Pain
Effects of Strength Training in Chronic Low Back Pain Patients
Although it is known that chronic low back pain (CLBP) have a multifactorial etiology, the investigations about it are mostly specific to each investigation area, making difficult to understand this complex condition.
- Trial name
- NCT03326362
- Testing
- Resistance training
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo