Clinical trials: Lumbar Back Pain
Chronic Pain
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time
The primary objective of this study is to evaluate efficacy of hydrocodone extended-release (ER) tablets compared with placebo in alleviating moderate to severe pain in patients with osteoarthritis or low back pain as assessed by…
- Trial name
- NCT01240863
- Testing
- Hydrocodone ER
- Where
- 73 sites in United States
- Volunteers
- 391 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Degenerative Disc Disease, Intervertebral Disc Disease
Treatment of Degenerative Disc Disease With Allogenic Mesenchymal Stem Cells (MSV)
In this study we want to evaluate the clinical use of allogenic mesenchymal stem cells (MSC), obtained from bone marrow of healthy donors, for treatment of Degenerative Disc Disease (DDD).
- Conditions
- Degenerative Disc Disease, Intervertebral Disc Disease, Low Back Pain
- Trial name
- Disc_allo (NCT01860417)
- Testing
- Allogenic Mesenchymal Stromal Cells, Mepivacaine
- Where
- 2 sites in Spain
- Volunteers
- 24 people
- Sponsor
- Red de Terapia Celular
Low Back Pain
COMPARISON OF THE LUMBAR EXTANSOR MUSCLES' ACTIVATIONS
Low back pain is a public health problem faced by 65-80% of the world's population at some point in their lives. Although the prognosis for low back pain is considered good, 80% of patients with acute low back pain recover within…
- Trial name
- NCT05748509
- Testing
- Surface EMG activations
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ankara Yildirim Beyazıt University
Low Back Pain
Disease Perception and Recovery From Low Back Pain
The main purpose of the study is to investigate the importance of patients' beliefs regarding staying active despite low back pain, among patients referred from general practice to secondary care treatment in Denmark.
- Trial name
- NCT03058315
- Where
- Denmark
- Volunteers
- 828 people
- Sponsor
- Central Jutland Regional Hospital
Chronic Low Back Pain
A Novel Non Invasive Brain Stimulation Based Treatment for Chronic Low Back Pain (CLBP)
Neuropathic pain results from damage to or dysfunction of the peripheral or central nervous system, rather than stimulation of pain receptors.
- Trial name
- NCT02393391
- Testing
- Neuroelectrics STARSTIM
- Volunteers
- 80 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Low Back Pain
Analysis of Orthopedic Patients Response to New Pain Modulating Substances and Drugs
Data of patient reported outcomes (PRO) are collected during treatment with various pain alleviation methods (drugs or substances)
- Trial name
- NCT03138460
- Testing
- standard medications crossed over to cannabis
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rabin Medical Center
Low Back Pain
Ultrasound-CT Fusion Image-guided Minimally Invasive Interventional Treatment of Lumbosacral Nerve Roots
The study is aimed at patients with low back and leg pain. The patients in the experimental group were guided by ultrasound-CT fusion imaging to insert the lumbar nerve root puncture needle.
- Trial name
- NCT04953520
- Testing
- ultrasound-CT fusion imaging, pure ultrasound guidance
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University Third Hospital
Vitamin D
Association of Vitamin D Intake, and Associated Factors with Low Back Pain: a Retrospective Cohort Study
While there have been studies indicating a connection between insufficient levels of vitamin D and persistent low back pain (LBP), there is still a lack of definitive evidence.
- Trial name
- NCT06765382
- Where
- Jordan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mutah University
Back Pain
Effect of Global Postural Reeducation (GPR) Program With Hamstring Stretch for Patients With Low Back Pain
The purpose of this study is to find out the additional effect of global re-education program with hamstring stretching in patients with low back pain.
- Trial name
- GPR (NCT04555668)
- Testing
- Global Postural Reeducation Program, Hamstring Stretch Program
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Riphah International University
Gastric Ulcer, Duodenal Ulcer
Comparative Efficacy & Safety Study of Esomeprazole Versus Placebo for the Prevention of Gastric and Duodenal Ulcers With NSAID
The purpose of this study is to assess the efficacy of esomeprazole (D961H) 20 mg versus placebo once daily for up to 24 weeks of treatment involving patients with a history of gastric and/or duodenal ulcers receiving daily…
- Conditions
- Gastric Ulcer, Duodenal Ulcer, Rheumatoid Arthritis, Osteoarthritis
- Trial name
- NCT00542789
- Testing
- Esomeprazole
- Where
- 39 sites in Japan
- Volunteers
- 343 people
- Sponsor
- AstraZeneca
Lumbar Disc Herniation, Lumbar Radiculopathy
The Role of Temporal Changes in Pain Response After Transforaminal Epidural Steroid Injection on Treatment Success
Transforaminal epidural steroid injection (TFESI) is a commonly used minimally invasive procedure for the treatment of lumbar radicular pain secondary to disc herniation.
- Conditions
- Lumbar Disc Herniation, Lumbar Radiculopathy, Radicular Low Back Pain, Sciatica
- Trial name
- NCT07367191
- Testing
- Transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Chronic Low-back Pain (cLBP)
Pain Assessment Through Integrated Neurophysiology and Multidimensional Profiling
This observational case-control study aims to investigate the central neurophysiological mechanisms underlying non-specific chronic low back pain (CLBP) with neural mechanosensitivity, with wearable Optically Pumped Magnetometers…
- Trial name
- PAIN-MAP (NCT07846163)
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Low Back Pain
Effectiveness of Mechanical Decompression for Low Back Pain Relief
Objective To demonstrate the effectiveness of a conservative treatment approach for chronic low back pain that addresses the underlying problem of intervertebral disc lesions and degenerative disc disease, namely vertebral…
- Trial name
- SpiDERS (NCT00704210)
- Testing
- SpineMed Table, Cert HealthSciences LLC
- Where
- United States
- Sponsor
- State University of New York - Upstate Medical University
Low Back Pain
The Back Exercises to Neutralize Disability Study
A pilot randomized control trial (RCT) to generate effect sizes on the effects of blood flow restricted exercise on trunk extensor cross-sectional area (primary outcome), strength and endurance, whole body and regional lean mass…
- Trial name
- BEND (NCT02308189)
- Testing
- Exercise with blood flow restriction, Exercise
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Ohio University
Postoperative Pain
The Effect of Intravenous Lidocaine on Pain After Lumbar Spinal Fusion
This prospective randomized study aims to evaluate the effectiveness of intravenous lidocaine injection on the relief of pain in patients undergoing 1-level posterior lumbar fusion.
- Trial name
- NCT01319682
- Testing
- Intravenous lidocaine injection, Intravenous normal saline injection
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Chung-Ang University Hospital
Spondylolysis, Spondylolisthesis
Rest Before Physical Therapy in Adolescents With Active Spondylolysis and Spondylolisthesis
This is a retrospective chart review with a short follow-up phone questionnaire for our patients who have been treated by Nationwide Children's Hospital physical therapy and sports medicine for a spondylolysis or…
- Conditions
- Spondylolysis, Spondylolisthesis, Low Back Pain
- Trial name
- NCT02332200
- Testing
- Physical Therapy
- Where
- 4 sites in United States
- Volunteers
- 196 people
- Sponsor
- Nationwide Children's Hospital
Chronic Low Back Pain
Intra-operative Ketamine Infusions in Opioid-dependent Patients With Chronic Lower Back Pain
Noxious stimuli occurring intraoperatively and postoperatively generate central sensitization, decreasing pain thresholds and ultimately increasing analgesic requirements.
- Trial name
- NCT00899600
- Testing
- Ketamine, Normal saline
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Low Back Pain
A Multilevel Intervention for Low Back Pain Management in Primary Care
Low back pain is the leading cause of disability worldwide and one of the main reasons for consulting in primary care. This project aims to improve the management of people with low back pain in primary care through an innovative…
- Trial name
- PRIME Back (NCT07137065)
- Testing
- PRImary care MultilEvel intervention for low back pain (PRIME), Usual Care
- Where
- 2 sites in Switzerland
- Volunteers
- 500 people
- Sponsor
- Guillaume Christe
Lumbar Disc Herniation, Sciatica
Bilateral Sacroiliac Joint (SIJ) Injection in Lumbar Disc Prolapse
Bilateral sacroiliac joint injection in symptomatic lumbar disc prolapse under ultrasound guidance and studying the effect of this technique on pain, spine mobility and activity of daily living.
- Conditions
- Lumbar Disc Herniation, Sciatica, Low Back Pain, Mechanical, Spine Stiffness
- Trial name
- NCT04326699
- Testing
- Bilateral SIJ injection
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Sohag University
Acute Low Back Pain
Efficacy and Safety of NVP-1203 in Patients With Acute Low Back Pain
The purpose of this study is to evaluate the efficacy and safety NVP-1203 in patients with Acute low back pain
- Trial name
- NCT03341832
- Testing
- NVP-1203, NVP-1203-R
- Where
- South Korea
- Volunteers
- 91 people
- Sponsor
- NVP Healthcare
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