Clinical trials: Lumbar Decompression
Syndrome, Manganese Neurotoxicity
Effects of Thoracolumbar Stabilization Versus Spinal Decompression Exercises on Maigne's Syndrome
The study was conducted to compare the effect of thoracolumbar stabilization exercises versus spinal decompression exercises on pain, range of motion, disability and posture in patients with maigne's syndrome.
- Trial name
- NCT07426900
- Testing
- Lumbothoracic stabilization exercises, Spinal decompression exercises, Standardized physical therapy treatment
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Lumbar Disc Herniation
Efficacy of Navigable Percutaneous Plasma Disc Decompression Device (L'DISQ) in Patients With Severe Lumbar Disc Herniation
This study aims to assess the clinical outcome of percutaneous disc decompression using the L'DISQ in patients with severe lumbar disc herniation (LDH).
- Trial name
- L'DISQ (NCT05231759)
- Testing
- L'DISQ
- Volunteers
- 30 people
- Sponsor
- Korea University Anam Hospital
Spinal Stenosis, Spondylolisthesis
Decompression vs. Fusion for Stable Degenerative Spondylolisthesis
The purpose of this study is to assess the feasibility of a full-scale multicenter randomized, controlled trial comparing the effectiveness of two surgical treatments for a condition associated with lumbar spinal stenosis called…
- Trial name
- NCT02348645
- Testing
- Spinal fusion, Spinal decompression
- Where
- 8 sites in Canada
- Volunteers
- 70 people
- Sponsor
- University Health Network, Toronto
Pain, Postoperative, Spine Surgery
Randomized Trial of Intraoperative IV Versus Preoperative Oral Acetaminophen During Ambulatory Lumbar Discectomy
Effective non-opioid analgesics are of particular interest in ambulatory surgery, as providers may be able to reduce pain while avoiding perioperative opioids that can delay same day discharge.
- Trial name
- NCT04574778
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Rothman Institute Orthopaedics
Cervical Foraminal Stenosis, Cervical Disc Herniation
Safety and Efficacy of Electromagnetic Navigation System Assisted Percutaneous Endoscopic Lumbar Decompression
There is a shallow learning curve with TELD (transforaminal endoscopic lumbar discectomy). The aim of this study is to assess the safety and efficacy of TELD assisted by electromagnetic navigation for treating lumbar disc…
- Trial name
- NCT05270486
- Testing
- Electromagnetic navigation system
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Régional de la Citadelle
Spinal Stenosis, Spinal Stenosis Lumbar
Decompression vs Physical Training for the Treatment of Lumbar Spinal Stenosis
Lumbar spinal stenosis (LSS) is characterized by low back and leg pain, walking disturbances and sometimes instability, impaired balance and numbness of the lower limbs.
- Conditions
- Spinal Stenosis, Spinal Stenosis Lumbar, Degeneration Lumbar Spine, Degeneration Spine
- Trial name
- UppSten (NCT03495661)
- Testing
- Decompression
- Where
- Sweden
- Volunteers
- 156 people
- Sponsor
- Uppsala University
Spinal Instability
CLUBE (UBE Stability / Dynamic Radio)
Degenerative pathologies of the spine affect a large proportion of the increasingly ageing population, and are a major public health issue.
- Trial name
- NCT06904326
- Testing
- Postoperative dynamic radiography
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Clinique Saint Jean, France
Degenerative Lumbar Spondylolisthesis
Long-term Reoperations After Lumbar Spinal Stenosis Surgery
Severe and persisting pain and disability due to a degenerative narrowing of the spinal canal, lumbar spinal stenosis, can be operated with a simple surgical decompression.
- Trial name
- NCT06407063
- Testing
- Micro-decompression alone, Decompression and instrumented fusion
- Where
- Norway
- Volunteers
- 794 people
- Sponsor
- University Hospital of North Norway
Lumbar Spinal Stenosis, Lumbar Radiculopathy
Continuous Erector Spinae Block for Analgesia Following Lumbar Decompression
Lumbar spinal surgery is common, and the incidence of spinal fusion has increased dramatically over the past three decades. Patients requiring spinal surgery are typically prescribed several analgesics, (including opioids) while…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Radiculopathy, Persistent Postsurgical Pain
- Trial name
- Lumbar-ESP (NCT06987409)
- Testing
- Continuous erector spinae plane block
- Volunteers
- 100 people
- Sponsor
- Nova Scotia Health Authority
Low Back Pain
Post-operative Epidural Analgesia After Minimally Invasive Lumbar Decompression and Fusion
Minimally invasive (MIS) lumbar decompression and fusion is a new procedure that aims to reduce post-operative pain, opioid consumption and related side effects, and length of hospital stay.
- Trial name
- NCT00644111
- Testing
- Bupivicaine, Hydromorphone
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University Health Network, Toronto
Lumbar Spinal Stenosis
The iO-Flex® Study: Evaluation of the Baxano iO-Flex® System for Decompressive Lumbar Surgery
The purpose of this study is to evaluate the clinical performance of the iO-Flex® System in reducing pain and symptom severity in patients with one or two level lumbar spinal stenosis that requires surgery.
- Trial name
- NCT01067014
- Testing
- Baxano iO-Flex® System
- Where
- 18 sites in United States
- Volunteers
- 75 people
- Sponsor
- Baxano Surgical, Inc.
Low Back Pain, Lumbar Disc Disease
Efficacy of Mechanical Traction and Spinal Decompression Treatments in Patients With Low Back Pain
Motorized traction and non-surgical spinal decompression treatments are relatively new treatments for which there is insufficient evidence in the literature.
- Conditions
- Low Back Pain, Lumbar Disc Disease, Lumbar Disc Herniation, Lumbar Radiculopathy
- Trial name
- NCT05617924
- Testing
- Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Afyonkarahisar Health Sciences University
Degenerative Spondylolisthesis, Spinal Stenosis
First-In-Human Study of AK1320 Encapsulated Microspheres (AK1320 MS)
The safety and efficacy of AK1320 MS will be evaluated in patients with degenerative spondylolisthesis and concomitant symptomatic spinal stenosis who are undergoing decompression and single level instrumented posterolateral…
- Trial name
- ENHANCE (NCT04483297)
- Testing
- AK1320 MS, Control
- Where
- 7 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Asahi Kasei Therapeutics Corporation
Stenoses, Spinal
Cost-effectiveness of Small Size Interarcuair Decompression Versus Extended Decompression in Patients With Intermittent Neurogenic Claudication
Rationale: Minimally invasive techniques have gained popularity to decompress lumbar spinal stenosis in the elderly. However, high quality evidence based on randomised controlled trials are not available.
- Trial name
- Size (NCT03480893)
- Testing
- small size interarcuair decompression, Laminectomy
- Where
- Netherlands
- Volunteers
- 174 people
- Sponsor
- Erasmus Medical Center
Lumbar Spinal Stenosis
Vertos Mild - Post Market Patient Outcomes
This is a single-center study evaluating the outcomes of patients with painful lumbar spinal stenosis who were treated with the mild procedure (minimally invasive lumbar decompression.
- Trial name
- NCT01076244
- Testing
- Minimally Invasive Lumbar Decompression
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The Center for Pain Relief, Inc.
Lumbar Spinal Stenosis, Spondylolisthesis, Grade 1
Pedicle Osteotomy for Stenosis Trial
This is a pivotal Randomized Clinical trial to compare the safety and effectiveness of the Pedicle Lengthening Osteotomy Procedure with implantation of the Altum® Device to open surgical decompression and Transforaminal Lumbar…
- Conditions
- Lumbar Spinal Stenosis, Spondylolisthesis, Grade 1, Neurogenic Claudication
- Trial name
- POST (NCT03381677)
- Testing
- Pedicle Lengthening Osteotomy with Altum® Device, Control
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- Innovative Surgical Designs
Patients With Spinal Stenosis Indicated for LLIF
Indirect vs. Direct Decompression for Treatment of Central Stenosis: RCT
This is a prospective, randomized clinical trial of patients undergoing 1-level lateral lumbar spinal fusion. This study seeks to randomize patients indicated for Lateral Lumbar Interbody Fusion (LLIF) into one of two groups…
- Trial name
- IDVD (NCT04708977)
- Testing
- One-level lateral lumbar interbody fusion with Indirect Decompression, One-level lateral lumbar interbody fusion with Direct Decompression
- Where
- United States
- Sponsor
- Hospital for Special Surgery, New York
Lumbar Decompression
MRI Outcomes of VersaWrap Nerve Protector Following Surgery
The purpose of this study is to evaluate enhancement patterns in magnetic resonance imaging (MRI) evidence following the use of VersaWrap in bilateral lumbar decompression surgeries.
- Trial name
- NCT06942819
- Testing
- VersaWrap Nerve Protector
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Research Source
Foraminal Stenosis
Comparative Outcomes of Conventional TLIF With Posterior Decompression Surgery Versus Endoscopic Foraminotomy Surgery
Comparative Outcomes of Conventional Transforaminal Lumbar Interbody Fusion With Posterior Decompression Surgery Versus Endoscopic Foraminotomy Surgery in Stable Lumbar Foraminal Stenosis An Ambi-directional Cohort Study
- Trial name
- TLIF (NCT06685575)
- Testing
- Endoscopic Foraminotomy Surgery
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Lumbar Disc Herniation, Lumbar Radiculopathy
PLDD With or Without Transforaminal Epidural Steroid Injection in Lumbar Disc Herniation
This prospective observational study aims to evaluate the clinical outcomes of patients with single-level lumbar disc herniation who undergo routine percutaneous laser disc decompression (PLDD).
- Trial name
- PLDD-TFESI (NCT07400068)
- Testing
- Percutaneous Laser Disc Decompression (PLDD), Transforaminal Anterior Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Mersin University