Clinical trials: Lumbar Osteoarthritis
Hip Osteoarthritis, Pain, Acute
Lumbar Plexus and Suprainguinal Fascia Iliaca Blocks For Total Hip Replacement
The nerves from lumbar plexus (LP) are the current target to achieve analgesia after a total hip arthroplasty (THA). Lumbar plexus block (LPB) is an alternative that provides optimal postoperative analgesia.
- Conditions
- Hip Osteoarthritis, Pain, Acute, Pain, Postoperative, Opioid Use
- Trial name
- NCT03744065
- Testing
- lumbar plexus block, suprainguinal fascia iliaca block
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- University of Chile
Facet Joint Arthrosis, Low Back Pain
Effectiveness of Pain and Exercise Training With Telerehabilitation on Lumbar Facet Joint Arthrosis
The study investigates the effects of pain and exercise training via telerehabilitation method on pain, pain beliefs, trunk mobility, functionality, and quality of life in individuals with low back pain caused by facet joint…
- Trial name
- NCT04981132
- Testing
- Pain Neuroscience education + Progressive therapeutic exercise training, Progressive therapeutic exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Okan University
Joint Pain
Synvisc Injections for Lumbar Facet Joint Pain
The objective of this investigation is to evaluate the safety and efficacy of viscosupplementation in treating symptomatic lumbar facet joint arthropathy.
- Trial name
- NCT00325845
- Testing
- Synvisc viscosupplementation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Sheltering Arms Physical Rehabilitation Hospitals
Lumbar Spine Degeneration, Arthrosis; Spine
Postoperative Bracing Patterns After Lumbar Surgery
A variety of postoperative bracing are routinely applied after spinal procedures but there are limited data regarding their efficacy, especially with the increasing use of internal fixation.Currently, no data are available…
- Conditions
- Lumbar Spine Degeneration, Arthrosis; Spine, Surgery
- Trial name
- NCT03427281
- Testing
- questionnaire
- Where
- Belgium
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Delirium, Lumbar Radiculopathy
Shaping Anesthetic Techniques to Reduce Post-operative Delirium
The purpose of this study is to determine if light sedation with spinal anesthesia reduces the incidence of delirium compared to receiving general anesthesia during spinal surgery in older adults.
- Conditions
- Delirium, Lumbar Radiculopathy, Lumbar Osteoarthritis, Lumbar Spine Disc Degeneration
- Trial name
- SHARP (NCT03133845)
- Testing
- Light sedation with propofol, Induction with propofol, Maintenance anesthetic using a volatile anesthetic
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- Johns Hopkins University
Osteoarthritis, Total Hip Arthroplasty
Lumbar Plexus Block Versus Quadratus Lumborum Block for Primary Anterior Total Hip Arthroplasty
Total hip arthroplasty (THA) is one of the most successful orthopedic procedures to effectively relieve pain and restore function in patients with end stage osteoarthritis.
- Trial name
- NCT03409900
- Testing
- LPB, QLB
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Wake Forest University Health Sciences
Low Back Pain, Osteoarthritis
Platelet-rich Plasma Infiltration Versus Corticosteroid Infiltration (Prednisolone) in Treatment of Lumbar Facet Joint Syndrome
The prevalence of low back pain is estimated at 90% . Recent studies have shown that 15% to 52% of back pain is attributable to facet joint syndrome .
- Trial name
- IAPRP (NCT05105256)
- Testing
- Prednisolone, Platelet-rich plasma
- Where
- France
- Volunteers
- 76 people
- Sponsor
- CHU de Reims
Osteoarthritis Hand, Lumbago
Cardiovascular Risk in Digital Osteoarthritis
The goal of this cross-sectional case control study is to investigate the cardiovascular risk in digital osteoarthritis. This study aims to compare the cardiovascular risk between group of patients with digital osteoarthritis and…
- Conditions
- Osteoarthritis Hand, Lumbago, Osteoporosis, Radiculopathy Lumbar
- Trial name
- RICARDI (NCT05923736)
- Testing
- Intima media thickness ultrasound, hand ultrasound, EndoPAT™ 2000 system
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Spondylosis, Osteoarthritis
Medial Branch Radiofrequency Ablation and Lumbar Multifidi
The purpose of this study is to evaluate the effects of lumbar medial branch radiofrequency ablation (RFA) on lumbar multifidi muscle size and clinical spinal stability.
- Trial name
- NCT03744260
- Testing
- Patients undergo ultrasound and lumbar MRI
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Columbia University
Osteoarthritis, Rheumatoid Arthritis
Injections of FloGraft Therapy, Autologous Stem Cells, or Platelet Rich Plasma for the Treatment of Degenerative Joint Pain
This study will assess the outcomes of three currently available regenerative treatments (FloGraft, autologous stem cell therapy, platelet rich plasma therapy) for painful degenerative conditions of the joints.
- Trial name
- NCT01978639
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Arizona Pain Specialists
Degenerative Osteoarthritis, Degenerative Lumbar Vertebra
Efficacy and Safety Study of Lumbar Interbody Fusion With MatriTMBONE Associated With Autologous Bone Marrow
The main objective of this clinical study is the estimation of the rate of intersomatic fusion observed 12 months after lumbar interbody fusion by posterior approach with PEEK interbody cage of fusion in PEEK performed with…
- Trial name
- MatriBone (NCT01335243)
- Testing
- The Transforaminal Lumbar Interbody Fusion (TLIF) surgery
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Bordeaux
Degenerative Arthropathy of Lumbar Spinal Facet Joint
Prognostic Factors in Zygapophyseal Osteoarthritis Infiltration: a Prospective Cohort Study
Magnet Resonance Image findings of facet osteoarthritis and patient characteristics are prognostic factors for improving or worsening the clinical outcome after treatment with facet infiltration.
- Trial name
- NCT03304730
- Where
- Brazil
- Volunteers
- 147 people
- Sponsor
- Hospital Israelita Albert Einstein
Back Pain Lower Back, Neck Pain
Success Rates and Safety of Steroid Injections in Managing Spinal and Sacro-Iliac Pain (CORTisone Injection Spine Study)
This study aims to analyze the efficacy and safety of different kinds of steroid injections for back pain, comparing different steroids, dosages, locations (epidural, facet joints, nerve blocks), and also the difference between…
- Conditions
- Back Pain Lower Back, Neck Pain, Radiculopathy Multiple Sites, Spinal Stenosis Cervicothoracic Region
- Trial name
- CORTISS (NCT07762170)
- Testing
- triamcinolone acetonide (Kenalog), Celestone Soluspan 6Mg/Ml Suspension for Injection, Depo-Medrol 40Mg/Ml Suspension for Injection
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Igor Wilderman. MD
Osteosynthesis, Mazor Robot
Study Comparing Arthrodesis Technique of Thoracic and/or Lumbar Spine by Posterior Approach Performed by Robot-assisted Surgery (Robot Mazor X Stealth ™) Versus Conventional Surgery
Osteosynthesis by pedicle screwing is the reference technique since the 1980s, due to the quality of the mechanical grip of the screw in the pedicle, despite difficulties of placing the implant in this narrow tunnel.
- Conditions
- Osteosynthesis, Mazor Robot, Spinal Surgery, Arthrosis; Spine
- Trial name
- ROBARTHRODESE (NCT05553028)
- Testing
- Computerised tomography
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Elsan
Platelet-Rich Plasma
Platelet-Rich Plasma (PRP) for Treatment of Symptomatic Lumbar Facet Syndrome of the Spine
The purpose of this study is to investigate the feasibility of standardized autologous platelet rich plasma injections into osteoarthritic lumbar facet joints to treat back pain and improve patient function.
- Trial name
- NCT04522674
- Testing
- Autologous platelet rich plasma
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Colorado, Denver
Hip Osteoarthritis
Lumbar Plexus vs Quadratus Lumborum Block in Post-operative Pain Following Total Hip Replacement
The Lumbar Plexus (LP) block is currently used as the standard-of-care regional anesthesia technique to provide postoperative pain management after primary hip replacement surgery at UPMC Shadyside Hospital.
- Trial name
- NCT03801265
- Testing
- Lumbar plexus block, Quadratus lumborum type 3 block, Ropivacaine injection
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Sharad Khetarpal
Chronic Pain, PERIPHERAL NEUROPATHY
Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain
To prospectively describe patient-centered and health utilization outcomes through 12 months after cryoneurolysis performed as routine clinical care for chronic pain at Yale.
- Conditions
- Chronic Pain, PERIPHERAL NEUROPATHY, Occipital Neuralgia, Chronic Hip Pain
- Trial name
- NCT07639060
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Yale University
Osteoarthritis, Hip
Systemic Steroids for Peripheral Nerve Blocks
This study will investigate the ability of systemic dexamethasone to prolong the sensory block duration for lumbar plexus nerve blockade.
- Trial name
- NCT02464176
- Testing
- Dexamethasone, Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Osteoarthritis, Pain
Norspan® Patches Versus Tramadol in Subjects With Chronic, Moderate to Severe Osteoarthritis Pain in the Hip Knee and/or Lumbar Spine
The primary objective of this equivalence study is to evaluate the efficacy of Norspan® patches versus Tramadol in subjects with chronic, moderate to severe osteoarthritis pain of the hip, knee and/or lumbar spine.
- Trial name
- NCT00426647
- Testing
- Buprenorphine, Tramadol
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Norpharma A/S
Knee Osteoarthritis
Effect of Lumbar Stabilization on Knee OA
This study will be conducted to investigate the role of lumbar core strengthening in reducing knee pain and disability, and improving knee proprioception and Quadriceps strength in patients with knee OA.
- Trial name
- NCT04458753
- Testing
- Lumbar focused exercises, Knee focused exercises
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University