Clinical trials: Lumbar Pain
Low Back Pain, Recurrent
Evaluation of Performances and Safety of the Medical Device Blueback® Physio for Patients With Chronic Low Back Pain
The main objective of this clinical investigation is to show the superiority of a rehabilitation based on the use of Blueback® Physio compared to a rehabilitation without the use of Blueback® Physio in terms of reducing the time…
- Trial name
- ABC-TRACC (NCT04592094)
- Testing
- Blueback® Physio
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Blueback
Low Back Pain, Mechanical, Low Back Pain
Efficacy and Safety of S (+) - Ibuprofen in the Treatment of Mechanical Low Back Pain
The purpose of this study is to evaluate the efficacy of S (+) - ibuprofen compared to an active treatment for pain control in individuals with at least moderate acute mechanical low back pain.
- Conditions
- Low Back Pain, Mechanical, Low Back Pain, Acute Low Back Pain
- Trial name
- APS002/2020 (NCT04772781)
- Testing
- S (+) - Ibuprofen, Ibuflex®
- Where
- Brazil
- Volunteers
- 177 people
- Sponsor
- Apsen Farmaceutica S.A.
Low Back Pain
SMART Clinical Study: Surgical Multi-center Assessment of RF Ablation for the Treatment of Vertebrogenic Back Pain
To evaluate the safety and efficacy of RF ablation using the Intracept Intraosseous Nerve Ablation System to ablate intraosseous nerves for the relief of chronic axial low back pain.
- Trial name
- SMART (NCT01446419)
- Testing
- Intracept Treatment
- Where
- 13 sites in United States
- Volunteers
- 225 people
- Sponsor
- Relievant Medsystems, Inc.
Low Back Pain
Safety And Efficacy Of Celecoxib Versus Sodium Diclofenac In The Treatment Of Acute Low Back Pain
To evaluate the safety and efficacy of celecoxib versus sodium diclofenac in subjects with acute low back pain
- Trial name
- NCT00640432
- Testing
- Diclofenac, Celecoxib
- Where
- 9 sites in Brazil
- Volunteers
- 244 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Recurrent Low Back Pain
Effect of Etoricoxib to Treat Chronic Low Back Pain (0663-042)
Study the effect of etoricoxib 60 mg and 90 mg compared to placebo to treat chronic low back pain.
- Trial name
- NCT00393211
- Testing
- MK0663, Etoricoxib / Duration of Treatment : 12 Weeks
- Volunteers
- 319 people
- Sponsor
- Organon and Co
Back Pain Without Radiation
Duloxetine Versus Placebo in Chronic Low Back Pain
The primary purpose of your participation in this study is to help answer the following research question, and not to provide you treatment for your condition.
- Trial name
- NCT00424593
- Testing
- Duloxetine
- Where
- 17 sites in Brazil, France and 3 more
- Volunteers
- 236 people
- Sponsor
- Eli Lilly and Company
Chronic Pain
A Single Arm, Open-label First In Human Study for Assessing the Safety and Performance of the EpiFinder in Subjects With Clinical Indication for Lumbar Epidural Steroids Injection (ESI)
The EpiFinder device, which is the investigational device in this study, is intended for use in epidural procedures, between a luer syringe and an epidural needle, to give the treating physician a clear indication that the needle…
- Trial name
- NCT04047927
- Testing
- EpiFinder
- Where
- 2 sites in Israel
- Volunteers
- 15 people
- Sponsor
- Omeq Medical
Low Back Pain, Low Back Pain, Recurrent
A Dose-ranging Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Low Back Pain
The purpose of this study is to compare the safety and effectiveness of different doses of JNJ-42160443 with placebo in the treatment of chronic, moderate to severe low back pain patients with a diagnosis of chronic low back pain.
- Trial name
- NCT00973024
- Testing
- JNJ-42160443 3 mg, JNJ-42160443 1 mg, JNJ-42160443 6 mg/3mg
- Where
- 60 sites in United States, Belgium and 2 more
- Volunteers
- 389 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Low Back Pain
Pilot Study to Evaluate The Effectiveness And Safety Of Axiom Worldwide Drx9000™ Spinal Decompression System
This pilot study will evaluate the effectiveness and safety of the Axiom Worldwide DRX9000 for active treatment of chronic low back pain.
- Trial name
- NCT00414596
- Testing
- DRX9000™
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- NEMA Research, Inc.
Chronic Low Back Pain, Osteoarthritis
Evaluate the Efficacy and Safety of Fasinumab in Patients With Moderate-to-Severe Chronic Low Back Pain and Osteoarthritis of the Hip or Knee
The primary objective of the study is to evaluate the efficacy of fasinumab in relieving Chronic low back pain (CLBP) as compared to placebo in participants with a clinical diagnosis of moderate-to-severe non-radicular CLBP and…
- Trial name
- FACT CLBP 1 (NCT03285646)
- Testing
- Fasinumab
- Where
- 56 sites in United States
- Volunteers
- 63 people
- Sponsor
- Regeneron Pharmaceuticals
Degenerative Disc Disease, Spine Fusion
MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion
This is a phase IV post-marketing study for MagnetOs Flex Matrix. MagnetOs Flex Matrix is a synthetic bone graft extender product that is routinely used by surgeons as a treatment for patients with degenerative disc disease and…
- Conditions
- Degenerative Disc Disease, Spine Fusion, Leg Pain and/or Back Pain
- Trial name
- PRECISE (NCT05037968)
- Testing
- MagnetOs Flex Matrix, Trinity Elite
- Where
- 9 sites in United States
- Volunteers
- 100 people
- Sponsor
- Kuros Biosurgery AG
Chronic Pain, Osteoarthritis
A Confirmatory Study of Fentanyl in Participants With Osteoarthritis or Low Back Pain
The purpose of this study is to evaluate efficacy and safety of fentanyl in opioid-naive participants with osteoarthritis (disorder, which is seen mostly in older persons, in which the joints become painful and stuff) or low back…
- Conditions
- Chronic Pain, Osteoarthritis, Low Back Pain
- Trial name
- NCT01008618
- Testing
- Fentanyl
- Where
- 59 sites in Japan
- Volunteers
- 218 people
- Sponsor
- Janssen Pharmaceutical K.K.
Chronic Low Back Pain
Pilot Study of the Efficacy and Safety of Lidoderm Patch in the Treatment of Low Back Pain
Patients with moderate to severe chronic Low Back Pain (LBP) despite current analgesic treatment participated in a Phase IV clinical trial to evaluate the analgesic efficacy of the lidocaine patch 5% compared to placebo in…
- Trial name
- NCT00904475
- Testing
- Lidoderm®
- Where
- 6 sites in United States
- Volunteers
- 102 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Low Back Pain
Evaluation of the Japet.W+ Medical Device for Low Back Pain Management
The JAPET.W+ medical device is a new dynamic distraction support system. It could be considered as a new solution in the therapeutic arsenal for managing common low back pain.
- Trial name
- EXODOMICILE (NCT07195422)
- Testing
- Japet.W+, Control (Standard treatment)
- Where
- 2 sites in France
- Volunteers
- 102 people
- Sponsor
- Japet Medical Devices
Acute Low Back Pain
A Two-Arm Study Comparing the Analgesic Efficacy and Safety of Acetaminophen and Tramadol Combination BID Versus Placebo for the Treatment of Acute Low Back Pain
A multi-center placebo controlled, double-blind, trial comparing the analgesic efficacy and safety of Acetram Contramid® BID versus placebo for the treatment of acute low back pain in patients between 18 and 80 yrs of age.
- Trial name
- NCT00643383
- Testing
- Combination drug (Acetaminophen + Tramadol)
- Where
- 38 sites in United States, Canada
- Volunteers
- 277 people
- Sponsor
- Labopharm Inc.
Low Back Pain
Study Evaluating Dexketoprofen Trometamol/Tramadol Hydrochloride Analgesic Efficacy in Acute Low Back Pain
A randomized, double-blind, study to evaluate the analgesic efficacy and safety of Dexketoprofen trometamol and Tramadol hydrochloride combination versus placebo on moderate to severe acute pain in patients with acute low back…
- Trial name
- Dante (NCT05170841)
- Testing
- Dexketoprofen Trometamol 25 mg/Tramadol Hydrochloride 75 mg, Tramadol Hydrochloride 100 mg
- Where
- Italy
- Volunteers
- 538 people
- Sponsor
- Menarini International Operations Luxembourg SA
Degenerative Disc Disease, Chronic Low-back Pain
Discure Technologies Feasibility Study for DDD
The objective of this study is to evaluate the safety and performance of the Discure System therapy in subjects with early to moderate degeneration of the disc (DDD).
- Conditions
- Degenerative Disc Disease, Chronic Low-back Pain, Discogenic Pain
- Trial name
- NCT06127745
- Testing
- Discure System
- Volunteers
- 20 people
- Sponsor
- Discure Technologies Ltd.
Disc Degenerative Disease, Back Pain
Intradiscal rhGDF-6 for the Treatment of Lumbar Disc Degeneration
The goal of this clinical trial is to find out if a new medicine can help people who have long-lasting back pain caused by damaged spinal discs. The study will also check if the medicine is safe to use.
- Trial name
- CBT005 (NCT07668466)
- Testing
- High Dose, Low Dose
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- Cartago Biotech Pty Ltd
Low Back Pain
Limiting Trunk Flexion as a Self-treatment for Low Back Pain
The purpose of the proposed study is to test the effect of an intervention technique that reduces trunk flexion upon rising, on the outcome measures of self-reported back pain and functional impairment in individuals with chronic…
- Trial name
- RST (NCT01830751)
- Testing
- Restrained Sitting Treatment
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Liberty Mutual Research Institute for Safety
Chronic Pain, Lower Back Pain Chronic
Lumbar Injectrode Feasibility Evaluation
The goal of this non-significant risk study is to determine whether stimulation with transcutaneous waveforms applied on the outside of the body and subcutaneously conducted to the lumbar medial branch nerve elicits visible (via…
- Trial name
- LIFE (NCT06206356)
- Testing
- PNS Injectrode F1
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Neuronoff, Inc