Clinical trials: Lumbar Pain
Type 2 Diabetes, Neuropathy, Painful
Methylglyoxal Evaluation in Humans
The investigators will test the hypothesis that patients with low back pain associated with lumbar disc aberrancy will have elevated MGO-protein levels circulating in the blood that are comparable to patients with painful…
- Conditions
- Type 2 Diabetes, Neuropathy, Painful, Chronic Low-back Pain, Lumbar Disc Herniation
- Trial name
- MEH (NCT05350553)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Surgery
Assessment of Low Level Laser Therapy for Late Postoperative Pain After Lumbar Fusion Surgery
The primary objective of this study is to assess whether or not low level laser therapy (LLLT) decreases pain in post-operative orthopedic patients following lumbar fusion surgery.
- Trial name
- NCT00422045
- Testing
- Low Level Laser Therapy
- Where
- United States
- Sponsor
- University of Toledo Health Science Campus
Chronic Non-specific Low Back Pain
Isokinetic Profile of Ankle Joint Muscles in Chronic Non Specific Low Back Pain Patients
Chronic non-specific low back pain and its resulting infirmity have become a huge health and socioeconomic burden. Low back pain is reportedly associated with decreased activities of daily living and quality of life.
- Trial name
- NCT07636967
- Testing
- Humac Isokinetic 2015 System 2
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Intervertebral Disc Displacement, Intervertebral Disc Degeneration
Safety and Efficacy With NOVOCART® Disc Plus (ADCT) for the Treatment of Degenerative Disc Disease in Lumbar Spine
NOVOCART® Disc plus is being investigated to explore its clinical applicability, safety and efficacy in the repair of a herniated disc with an indication for an elective sequestrectomy, and of the adjacent degenerated disc, if…
- Trial name
- NDisc (NCT01640457)
- Testing
- NOVOCART® Disc plus, NOVOCART® Disc basic
- Where
- 10 sites in Austria, Germany
- Volunteers
- 120 people
- Sponsor
- Tetec AG
Back Pain
Celebrex vs Tramadol in the Treatment of Chronic Lower Back Pain.
This study investigates if Celebrex is as effective as tramadol hydrochloride (Ultram) for patients with chronic low back pain, when administered over a 6-week period.
- Trial name
- NCT00290901
- Testing
- Tramadol Hydrochloride 50mg, Celebrex 200mg
- Where
- 54 sites in United States, Puerto Rico
- Volunteers
- 754 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
KINESIOTAPING
The Effect of Kinesiotaping in Pregnant Women
The aim of this study is to examine the effect of an exercise program combined with Kinesio Taping (KT) and sham KT on clinical parameters in pregnant women with low back pain.
- Trial name
- NCT06709105
- Testing
- Kinesiotape
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Firat University
Low Back Pain, Disc, Herniated
Motor Control Mechanisms by CNS of Tuina in Patients With Lumbar Disk Herniation
Lumbar disk herniation (LDH)is a prevalent health problem around the world. It can cause symptoms of low back pain, numbness or weakness.The understanding of low back pain in traditional Chinese medicine(TCM) theory"unbalanced…
- Trial name
- NCT03475095
- Testing
- Tuina
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Work-related Injury, Burnout
The Effect of Exercise and Ergonomics Training Program on Musculoskeletal Disorders in Teachers
This randomized controlled trial tested whether adding a 12-week structured exercise program to ergonomics training improves low back and neck disability, burnout, musculoskeletal symptoms, and pain intensity in schoolteachers…
- Conditions
- Work-related Injury, Burnout, Neck Pain, Low Back Pain
- Trial name
- NCT07442383
- Testing
- ergonomics training, Structured exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Uskudar University
Low Back Pain, Mechanical
An Efficacy Study of Exercise Rehabilitation on Pain and Disability for Patients With Non-specific Low Back Pain
The primary objective of this study is to compare the efficacy of two different exercise programs for the reduction of pain and disability in a specific subgroup of NSLBP patients and aims to investigate the additive effect of…
- Trial name
- LBP-RCT (NCT01567566)
- Testing
- exercise rehabilitation program
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Running Injury Clinic
Lower Back Pain, Pelvic Pain
Musculoskeletal and Obstetric Management Study
The investigators propose such a trial to compare a Musculoskeletal and Obstetric Management (MOM) program to standard obstetric care alone for lower back pain/pelvic pain (LBP/PP) during and after pregnancy.
- Conditions
- Lower Back Pain, Pelvic Pain, Musculoskeletal Pain
- Trial name
- MOMS (NCT00905112)
- Testing
- Manual Therapy, Standard OB Care
- Where
- 3 sites in United States
- Volunteers
- 160 people
- Sponsor
- Logan College of Chiropractic
Lower Back Pain, Degenerative Disc Disease (DDD)
Luna Interbody System for Fusion Trial
The purpose of this trial is to evaluate the performance, safety and effectiveness of the Luna system for the treatment of degenerative disc disease.
- Trial name
- LIFT (NCT01551901)
- Testing
- Spinal fusion
- Where
- 5 sites in Belgium, Germany
- Volunteers
- 100 people
- Sponsor
- Benvenue Medical, Inc.
Postoperative Pain
Effects of Nerve Block on Knee Function After Knee Replacement
Early physical therapy after knee surgery is very painful on top of pain from surgery. Pain following surgery can limit recovery. One way to treat pain is by giving intravenous (IV) pain medication with morphine.
- Trial name
- NCT00358241
- Testing
- Nerve block
- Where
- United States
- Sponsor
- Johns Hopkins University
Low Back Pain
Effects of Functional Taping on Static Postural Control in Patients With Non-specific Chronic Low Back Pain
Background: Low back pain is a major public health problem that affects most people at some point in life, and results in major psychosocial, economic, functional and physical consequences that can last for days and months.
- Trial name
- NCT02546466
- Testing
- Functional Star-shape taping (SFT), Minimal Intervention Strategy (MIS)
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo
Low Back Pain
Dare to Move: Treatment of Movement Phobia in Patient With Low Back Pain
Unspecific low back pain (LBP) is a major world wide health problem. The purpose of this study is to improve the care of LBP. Our hypothesis is that Cognitive Behavioural Therapy (CBT) with physical intervention during group…
- Trial name
- Ryggbra (NCT01158339)
- Testing
- Arm 2: CBGT-ISE, Arm 1: CBGT
- Where
- Norway
- Volunteers
- 90 people
- Sponsor
- Norwegian University of Science and Technology
Chronic Low Back Pain, Spinal Cord Injury
SERENITY Study of Chronic Pain Interference in Adults
SERENITY is a remote observational study designed to characterize inter-individual differences in chronic pain among adults with chronic low back pain and adults with spinal cord injury-related neuropathic pain.
- Conditions
- Chronic Low Back Pain, Spinal Cord Injury, Neuropathic Pain, Chronic Pain
- Trial name
- SERENITY (NCT07820475)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Minnesota
Chronic Low Back Pain (CLBP), Chronic Insomnia
Studying the Neurobiological Mechanisms of Non-specific Chronic Low Back Pain and Chronic Insomnia: a Four-group Cross-sectional Study
This study is a part of a larger project aiming to evaluate the neurobiological mechanisms underlying the relationship between sleep and pain in people with non-specific chronic low back pain.
- Conditions
- Chronic Low Back Pain (CLBP), Chronic Insomnia, Neuroinflammation
- Trial name
- SY-NAPS-CS (NCT06973837)
- Testing
- Real-life monitoring, experimental pain testing, brain imaging, blood and stool sampling.
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Back Pain Lower Back Chronic
A Study of Duloxetine (LY248686) in Participants With Chronic Low Back Pain
The purpose of the study is to assess the efficacy and safety of duloxetine in participants with Chronic Low Back Pain (CLBP).
- Trial name
- NCT01855919
- Testing
- Duloxetine
- Where
- Japan
- Volunteers
- 458 people
- Sponsor
- Eli Lilly and Company
Low Back Pain, Mechanical, Spinal Stenosis
Investigation of Hypermobility, Biomarkers, and Pain Generators in Chronic Pain Patients
Observational study of axial spine pain and hyperflexibility. Patients will receive physical exam maneuvers (traditional straight leg raise, FABER, facet loading as well as Beighton's hypermobility score) and blood / urine /…
- Conditions
- Low Back Pain, Mechanical, Spinal Stenosis, Nerve Root Disorder, Radiculopathy, Cervical
- Trial name
- Hypermoble (NCT02761928)
- Testing
- Beighton score for hypermobility
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- The University of Texas Health Science Center, Houston
Low Back Pain
Active Break Intervention on Low Back Pain and Musculoskeletal Discomfort During Prolonged Sitting Among Young People
The most recent evidence showed that the COVID-19 (coronavirus disease 2019, National Institutes of Health) pandemic caused an increase in low back pain (LBP) prevalence and intensity among young people.
- Trial name
- NCT05810519
- Testing
- Active break with the proposed lumbar and hip extension exercises, Self-care recommendations
- Where
- Poland
- Volunteers
- 25 people
- Sponsor
- Józef Piłsudski University of Physical Education
Metabolic Syndrome, Physical Activity
The Effectiveness of Dry Needling and Classic Physiotherapy Programs in The Patients Suffering From Chronic Low Back Pain Caused by Lumbar Disc Hernia
Aim: This study was planned for comparing physical activity levels, nutrition quality and quality of life of the individuals that are diagnosed with and without metabolic syndrome (MetS) and that live in the Turkish Republic of…
- Conditions
- Metabolic Syndrome, Physical Activity, Quality of Life
- Trial name
- NCT02865200
- Testing
- Dry Needling Application, Classic Physiotherapy Program
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
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