Clinical trials: Lumbar Spine Fusion Surgery
Lumbar Surgery
Enhanced Recovery After Surgery in Orthopaedic Spine Surgery
This study aims to determine the impact and effect of enhanced recovery after surgery (ERAS) principles in the recovery and rehabilitation of patients following elective orthopaedic spine surgery with a specific emphasis on oral…
- Trial name
- ERAS (NCT04562610)
- Testing
- Intravenous Infusion group, All oral administration group
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of California, Davis
Degenerative Disc Disease
Study of an Expandable Interbody Device for the Lumbar Spine
The primary objective of this study is to evaluate the safety and efficacy of CALIBER expandable spacer for the treatment of degenerative disc disease.
- Trial name
- CALIBER (NCT02075554)
- Testing
- CALIBER
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Globus Medical Inc
Osteoporosis, Fusion of Spine, Lumbar Region
Preoperative Teriparatide Use on Insertional Torque of Pedicle Screws for Lumbar Fusion Surgery
This project aims to investigate any difference of insertional torque strength for osteoporotic patients with preoperative 1-month teriparatide injections versus those without.
- Trial name
- NCT03770338
- Testing
- Teriparatide
- Where
- 3 sites in Hong Kong
- Volunteers
- 192 people
- Sponsor
- The University of Hong Kong
Spondylolisthesis, Erosive Osteochondrosis in L2-S1
Comparison of Standard Fusion With "Topping Off"-System in Lumbar Spine
Does a new "topping-off" device lead to a better clinical outcome compared to standard fusion? Does this device prevent the development of adjacent instability? Does radiological adjacent instability correlate with clinical…
- Trial name
- Topping-off (NCT01224379)
- Testing
- Topping off system, monosegmental PLIF
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Cologne
Transforaminal Lumbar Interbody Fusion Surgery
A Post-marketing Study to Evaluate a Novel Surgical Monitoring Technique Using the EARP Nerve Cuff in TLIF Surgery.
The purpose of this study is to evaluate the differences (the effectiveness and the safety) between two different nerve and muscle monitoring devices currently available during a TLIF surgery.
- Trial name
- NCT06204900
- Testing
- Nerve Cuff and Retractor System
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Retropsoas Technologies, LLC
Spinal Fusion, Spinal Stenosis
Vancomycin Powder Combined With Autogenous Bone Graft as a Prevention for Post-operative Infection for Spine Surgery
Deep surgical site infection (DSSI) is one of the most challenging complications for spinal surgeons and can lead to a poor clinical outcome.
- Conditions
- Spinal Fusion, Spinal Stenosis, Spondylolisthesis
- Trial name
- NCT03883022
- Testing
- with U-VANCO (vancomycin hydrochloride), without U-VANCO (vancomycin hydrochloride)
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Spinal Fusion
Minimally Invasive Versus Open Transforaminal Lumbar Interbody Fusion
A study that compares between Open TLIF and Minimally invasive TLIF regarding patients' functional status(Oswestry Disability index)as a primary outcome measure.
- Trial name
- NCT03692845
- Testing
- Transforaminal Lumbar Interbody Fusion either open or minimally invasive
- Volunteers
- 60 people
- Sponsor
- Assiut University
Spinal Stenosis, Spondylolisthesis
Decompression vs. Fusion for Stable Degenerative Spondylolisthesis
The purpose of this study is to assess the feasibility of a full-scale multicenter randomized, controlled trial comparing the effectiveness of two surgical treatments for a condition associated with lumbar spinal stenosis called…
- Trial name
- NCT02348645
- Testing
- Spinal fusion, Spinal decompression
- Where
- 8 sites in Canada
- Volunteers
- 70 people
- Sponsor
- University Health Network, Toronto
Enhanced Recovery After Surgery, Spine Surgery
Enhanced Recovery After Spine Surgery
Enhanced recovery pathways (ERP) after surgery have been shown to decrease length of stay and perioperative complications in a range of surgical specialties.
- Trial name
- NCT02949518
- Testing
- Enhanced Recovery Pathway (ERP) for Spine
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Spondylolisthesis, Degenerative Lumbar Disc Disease
Spine Research With Roentgen Stereophotogrammetric Analysis
The purpose of this study is to gather information on the effectiveness of a new spine implant for patients who require spinal fusion surgery.
- Conditions
- Spondylolisthesis, Degenerative Lumbar Disc Disease, Spinal Stenosis
- Trial name
- SpineRSA (NCT00493558)
- Testing
- Trabecular Metal Intervertebral Cage with RSA beads
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- Nova Scotia Health Authority
Low Back Pain, Lumbar Spinal Fusion
Back to Life - Early Rehabilitation Therapy for Patients Undergoing Lumbar Spinal Fusion
Aim This study aims to assess the effectiveness of an early intervention comprising individually tailored physiotherapy, including dialogue, education, and graded activity, following lumbar spinal fusion surgery.
- Trial name
- Back to Life (NCT07378735)
- Testing
- SOGA - Socratic dialogue and Graded Activity, SOGA - SOcratic dialougue and Graded-Activity, SOGA - SOcratic dialogue and Graded-Activity
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hyperalgesia
Local Anesthetic Infiltration to Prevent Postoperative Pain After Lumbar Surgery
Posterior lumbar arthrodesis causes severe postoperative pain, hampering patients's postoperative reconvalescence especially functional rehabilitation.
- Trial name
- ICALP (NCT00825422)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Scoliosis, Scoliosis; Adolescence
Study Comparing the PathKeeper System for Pedicle Screw Positioning in Spine Surgery With Traditional Care
The goal of this is to evaluate performance of the Pathkeeper Surgical System. The main question[s]it aims to answer are: 1) evaluate pedicle screw position Participants will in compare Experimental arm: PathKeeper System (PKS)…
- Conditions
- Scoliosis, Scoliosis; Adolescence, Scoliosis Kyphosis, Scoliosis Lumbar Region
- Trial name
- PKSforPSP (NCT06554093)
- Testing
- Medical Device - PKS
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Deep Health Ltd.
Lumbar Spine Degeneration
Study Using the SpinalStim Device Following Lumbar Fusion Surgery
This study examines the effect of adjunctive use of the SpinalStim bone growth stimulator on lumbar fusion rate in high risk subjects who have had lumbar fusion surgery.
- Trial name
- NCT03176303
- Testing
- SpinalStim
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- Orthofix Inc.