Clinical trials: Lumbar Spondylolisthesis
Enhanced Recovery After Surgery, Spinal Fusion
Enhanced Recovery After Surgery in Oblique Lumbar Interbody Fusion
This study is a randomized controlled non-inferiority trial designed to evaluate the impact of implementing the 'Early Recovery After Surgery Clinical Pathway (ERAS CP)' on patient-reported pain levels at the time of discharge…
- Conditions
- Enhanced Recovery After Surgery, Spinal Fusion, Lumbar Spinal Stenosis, Lumbar Spondylolisthesis
- Trial name
- NCT05959343
- Testing
- Enhanced Recovery After Surgery program for Oblique Lumbar Interbody Fusion
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Seoul National University Hospital
Lumbar Spinal Stenosis, Spondylolisthesis
Post-market Study of the TOPS™ System
This Single-Arm Post-Marketing Evaluation will gauge the improvement in function and pain for lumbar spinal stenosis and spondylolisthesis patients with the TOPS System.
- Trial name
- NCT02234154
- Testing
- TOPS System
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Premia Spine
Degenerative Lumbar Spondylolisthesis
A Prospective Pilot Study of the OP-1 Putty in Uninstrumented Posterolateral Fusions
This study will explore the use of OP-1 Putty in conjunction with surgical treatment for the treatment of spinal decompression and lumbar spinal fusion.
- Trial name
- NCT00679107
- Testing
- Use of OP-1 Putty in Uninstrumented posterolateral fusion
- Where
- 5 sites in United States
- Volunteers
- 48 people
- Sponsor
- Olympus Biotech Corporation
Lumbar Spondylosis, Lumbar Spondylolisthesis
Use of Forteo (Teriparatide) in Posterolateral Lumbar Spine Fusion
The purpose of this study is to determine the effects of 12 weeks of daily treatment with teriparatide on spine fusion in adult patients who are undergoing multi-level posterolateral spine fusion surgery for degenerative…
- Conditions
- Lumbar Spondylosis, Lumbar Spondylolisthesis, Adult Degenerative Lumbar Scoliosis
- Trial name
- NCT01292252
- Testing
- teriparatide
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Shane Burch
Degenerative Spondylolisthesis, Lumbar Spinal Stenosis
Degenerative Spondylolisthesis Accompanying LSS: Do We Need Fusion?
This study aimed to compare clinical results of decompression alone using minimal invasive unilateral laminotomy for bilateral decompression versus classical decompression and instrumentation and fusion.
- Conditions
- Degenerative Spondylolisthesis, Lumbar Spinal Stenosis, Fusion
- Trial name
- NCT07410871
- Testing
- Unilateral laminotomy decompression, Decompression and fusion
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Kafrelsheikh University
Lumbar Spondylolisthesis, Grade 1 Spondylolisthesis
SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion
The purpose of the project is to perform an RCT comparing patient satisfaction and outcome with or without the use of an expert panel.
- Conditions
- Lumbar Spondylolisthesis, Grade 1 Spondylolisthesis, Lumbar Spinal Stenosis, Degenerative Spondylolisthesis
- Trial name
- SLIPII (NCT03570801)
- Testing
- Expert Panel Review
- Where
- 17 sites in United States, Canada
- Volunteers
- 662 people
- Sponsor
- Lahey Clinic
Degenerative Spondylolisthesis
SPONGIT: Comparison of Two Surgical Approaches in the Treatment of Degenerative Spondylolysthesis
This trial, conducted in adult patients with degenerative spondylolisthesis needing surgical treatment at one level, aimed at comparing two approaches of spinal fusion.
- Trial name
- SPONGIT (NCT00869882)
- Testing
- Circumferential arthrodesis, Posterolateral fusion with instrumentation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Bordeaux
Low Back Pain, Spondylolisthesis
Evaluation of Aspen Spinous Process Fixation System and PLIF Technique for the Treatment of Low Back Pain
Lumbar spinal fusion was introduced approximately 70 years ago and has evolved as a treatment option for symptomatic spinal instability, spinal stenosis, spondylolisthesis, and degenerative scoliosis.
- Conditions
- Low Back Pain, Spondylolisthesis, Spondylosis, Spinal Instability
- Trial name
- NCT01918943
- Testing
- PLIF and Aspen (spinous process fixation device)
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- American British Cowdray Medical Center
Spinal Instability
The Rehabilitation Outcome of Patients With Lumbar Spondylolisthesis. A Prospective Randomized Study
Patients with degenerative lumbar spondylolisthesis usually are present with low back pain, muscle spasm and weakness, radicular symptoms, intermittent claudication, insomnia, even urine or stool incontinence.
- Trial name
- NCT02435485
- Testing
- Biodex balance training, Rehabilitation including core spinal stabilization exercise
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Chang Gung Memorial Hospital
Intervertebral Disc Degeneration
5-Year Global Study on MAST™ Minimally Invasive Fusion Procedures to Treat Degenerative Lumbar Spine (MASTERS-D2)
The purpose of this study is to evaluate the effectiveness of MAST techniques for anterior/lateral and posterior approaches in Degenerative Disc Disease (DDD) patients with spondylolisthesis (≥ grade I).
- Trial name
- MASTERS-D2 (NCT02617563)
- Testing
- Minimally invasive lumbar fusion
- Where
- 27 sites in Argentina, Austria and 15 more
- Volunteers
- 361 people
- Sponsor
- Medtronic Spinal and Biologics
Lumbar Spinal Stenosis, Lumbar Spondylolisthesis
Effectiveness and Safety of Korean Medicine for Low Back Pain or Sciatica Due to Lumbar Stenosis/Spondylolisthesis
A prospective observational study investigating the effectiveness and safety of integrative Korean medicine treatment in lumbar stenosis or spondylolisthesis patients with low back pain or sciatica at 3 locations of Jaseng…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Low Back Pain, Sciatica
- Trial name
- NCT03879447
- Testing
- Herbal medicine, Chuna manual medicine, Bee venom pharmacopuncture
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Jaseng Medical Foundation
Distal Radius Fractures, Degenerative Lumbar Spondylolisthesis
Long-term Safety Trial with NVDX3
An study evaluating the long-term safety of all patients previously treated with NVDX3.
- Trial name
- X3LTFU (NCT06532253)
- Testing
- NVDX3
- Where
- Luxembourg
- Volunteers
- 15 people
- Sponsor
- Novadip Biosciences
Lumbar Degenerative Spondylolisthesis
Clinical Study on the Therapeutic Efficacy of Biportal Endoscopic Decompression Spine Surgery and Lumbar Decompression Fusion Surgery in the Treatment of Degenerative Lumbar Spondylolisthesis
This study aims to systematically evaluate the therapeutic efficacy of dual-channel endoscopic spinal decompression versus lumbar decompression with fusion for degenerative lumbar spondylolisthesis.
- Trial name
- NCT07289737
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Degenerative Lumbar Spine Diseases, Lumbar Spinal Instability
Role of Intraoperative Computed Tomography in Assessment of Spine Instability in Lumbar Degenerative Disease
This study examines how well computed tomography (CT) imaging performed during spine surgery - known as intraoperative CT - can detect instability in the lower (lumbar) part of the spine.
- Conditions
- Degenerative Lumbar Spine Diseases, Lumbar Spinal Instability, Degenerative Spondylolisthesis, Lumbar Spinal Stenosis
- Trial name
- INSIGHT-CT (NCT07644507)
- Testing
- Intraoperative Computed Tomography (O-arm)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
Degenerative Instability, Spondylolisthesis
PMCF Study on the Safety and Performance of PROSPACE 3D / PROSPACE 3D OBLIQUE / TSPACE 3D
Prospective, pure data collection of all PROSPACE 3D, PROSPACE 3D Oblique, TSPACE 3D patients in selected centers (not interventional, multicenter
- Conditions
- Degenerative Instability, Spondylolisthesis, Post-discectomy Syndrome, Post-traumatic Instabilities
- Trial name
- PROTONTO (NCT04542577)
- Where
- 2 sites in Germany
- Volunteers
- 208 people
- Sponsor
- Aesculap AG
Spine Degeneration
Risk Factors of Paraspinal Muscles in Degenerative Lumbar Spondylolisthesis
This is a retrospectively observational study. The goal of this observational study is to analyze the risk factors of paraspinal muscles associated with the occurrence of spondylolisthesis in patients with degenerative lumbar…
- Trial name
- RFPMDLS (NCT06797700)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- The First People's Hospital of Yunnan
Degenerative Disc Disease, Spondylolisthesis
Prospective, Multi-center Study to Assess Posterolateral Fusion Using FIBERGRAFT
This is a prospective, non-randomized (single arm), multi-center, post-market clinical study designed to evaluate FIBERGRAFT® BG Matrix mixed with autograft and bone marrow aspirate in up to 150 subjects with degenerative disc…
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Spinal Stenosis Lumbar
- Trial name
- NCT03884283
- Testing
- FIBERGRAFT BG Matrix
- Where
- 9 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Prosidyan, Inc.
Degenerative Lumbar Spondylolisthesis
Degenerative Spondylolisthesis; Micro-decompression vs Decompression + Instrumented Fusion; Long Term Follow up
In many countries a majority of patients with degenerative spondylolisthesis are operated on with decompression plus instrumented fusion, but the scientific evidence for adding fusion is controversial.
- Trial name
- DS-registry (NCT03469791)
- Testing
- Surgical treatment of Degenerative Spondylolisthesis
- Where
- Norway
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Spondylolisthesis
Validation of Appropriateness Criteria for the Surgical Treatment of Lumbar Degenerative Spondylolisthesis
The main objective of this study is the external validation of the appropriateness criteria for the surgical treatment of Lumbar Degenerative Spondylolisthesis.
- Trial name
- NCT02966639
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Degenerative Spondylolisthesis, Lumbar Spinal Stenosis
LimiFlex Clinical Trial for the Treatment of Degenerative Spondylolisthesis With Spinal Stenosis
The LimiFlex™ Clinical Trial is a prospective, concurrently controlled, multi-center study to evaluate the safety and effectiveness of decompression and stabilization with the Empirical Spine LimiFlex™ Paraspinous Tension Band…
- Trial name
- NCT03115983
- Testing
- LimiFlex, Fusion Instrumentation, Decompression
- Where
- 28 sites in United States
- Volunteers
- 299 people
- Sponsor
- Empirical Spine, Inc.