Clinical trials: Lumbar Surgery
Lumbar Spine Injury
The Use of Dantrolene to Improve Analgesia in Posterior Lumbar Surgery
The purpose of this study is to determine whether administration of a non-centrally acting muscle relaxants will improve the Overall Benefit of Analgesia Score (OBAS), and Richmond Agitation Sedation Scale (RASS) scores in…
- Trial name
- NCT03762109
- Testing
- Dantrolene
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Beth Israel Deaconess Medical Center
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Effect of Irrigation Pressure on Postoperative Complications and Surgical Field Clarity in Unilateral Biportal Endoscopic Surgery
This study is being done to find out if the height of the fluid bag and the direction of the surgical cut affect the pressure of the fluid used during unilateral biportal endoscopic (UBE) spine surgery.
- Conditions
- Lumbar Disc Herniation, Lumbar Spinal Stenosis, Lumbar Degenerative Disease
- Trial name
- NCT07837427
- Testing
- Unilateral Biportal Endoscopic Surgery
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Fan Zhang
Back Pain
Spinal Cord Stimulation for Chronic and Intractable Back Pain
The purpose of this study is to evaluate the efficacy of spinal cord stimulation (SCS) using the Precision implantable neurostimulation device for chronic and intractable back pain in subjects who are not candidates for surgery…
- Trial name
- NCT00370695
- Testing
- Precision Spinal Cord Stimulation System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Boston Scientific Corporation
Lumbar Degenerative Disease
CONDUIT™ Anterior Lumbar Interbody Fusion (ALIF) Cage System in Lumbar Degenerative Disease
This will be a prospective, multi-centre study at a National Tertiary Referral Centre for spinal trauma and spinal cord injuries, serving a catchment area of 5 million people.
- Trial name
- NCT06940453
- Testing
- CONDUIT
- Where
- Ireland
- Volunteers
- 35 people
- Sponsor
- University College Dublin
Lumbar Spinal Stenosis, Spondylolisthesis
Minuteman Spinal Fusion Implant Versus Surgical Decompression for Lumbar Spinal Stenosis
Lumbar spinal stenosis (LSS), is a common disorder of narrowing of the spinal canal in the lower part of the back. This causes discomfort in the legs when standing or walking because of pressure on the spinal nerves.There are…
- Conditions
- Lumbar Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease
- Trial name
- NCT01455805
- Testing
- Minuteman Fusion Implant, surgical decompression
- Where
- 4 sites in United Kingdom
- Volunteers
- 48 people
- Sponsor
- Spinal Simplicity LLC
Single Level Lumbar Decompression and Fusion Spine Surgery
Multimodal Analgesia vs. Routine Care Pain Management for Lumbar Spine Fusion Surgery: A Prospective Randomized Study
The purpose of this study is to determine if post-operative pain and rate of recovery are improved in patients undergoing spine surgery using MMA (multimodal analgesia) compared to usual analgsic care.
- Trial name
- NCT02202369
- Testing
- Multimodal Analgesia Treatment, Standard of Care Pain Management Protocol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Lumbar Decompression
MRI Outcomes of VersaWrap Nerve Protector Following Surgery
The purpose of this study is to evaluate enhancement patterns in magnetic resonance imaging (MRI) evidence following the use of VersaWrap in bilateral lumbar decompression surgeries.
- Trial name
- NCT06942819
- Testing
- VersaWrap Nerve Protector
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Research Source
Knee Arthroscopy Surgery
Ultrasound Plus Nerve Stimulator Versus Nerve Stimulator Guided Lumbar Plexus Block
Ultrasound imaging, an effective tool to localize peripheral nerves, may facilitate block performance. It allows direct visualization of nerve structures, needle guidance in real-time to the target, and observation of local…
- Trial name
- NCT02020096
- Testing
- Ultrasound and nerve stimulator guided lumbar plexus block, Nerve stimulator guided lumbar plexus block
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Huazhong University of Science and Technology
Pain, Postoperative, Pain, Acute
Opioid Sparing Anesthesia in Lumbar Spine Surgery
The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus remifentanil analgesia in lumbar…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Nociceptive
- Trial name
- NCT05594407
- Testing
- dexmedetomidine-ketamine-lidocaine, Remifentanil
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aretaieion University Hospital
Paraspinal Muscles, Degenerative Lumbar Diseases
The Impact of Paraspinal Muscle Atrophy in Spine Surgeries
The goal of this observational study is to learn about the role of pre-operative paraspinal muscle atrophy in outcomes of lumbar spine fusion surgeries in patients with degenerative lumbar spine diseases.
- Trial name
- NCT07002918
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Assiut University
Failed Back Surgery Syndrome (FBSS)
Caudal Epidural With or Without Lumbar Sympathetic Block for Redo Lumbar Surgery
Comparing the analgesic effect of caudal epidural versus combined lumbar sympathetic block with caudal epidural in patients undergoing redo spinal surgery.
- Trial name
- CLEARS (NCT07199816)
- Testing
- Fluoroscopy-Guided Caudal Epidural Block, Combined Lumbar Sympathetic Ganglion Block and Caudal Epidural Block
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Hebatullah Mohammed Abdelmageed
Hip Surgery, Femoral Neck Fractures
Comparison of Lumbar Erector Spinae Plane Block and Spinal Anesthesia in Hip and Proximal Femur Surgery
Hip and proximal femur surgeries are commonly performed in elderly patients and require anesthetic techniques that provide adequate surgical anesthesia while minimizing the need for additional opioid administration.
- Trial name
- L-ESP-HIP Stud (NCT07427082)
- Testing
- Ultrasound-Guided Lumbar Erector Spinae Plane Block (L4), Spinal Anesthesia (L4-L5)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Gaziantep City Hospital
Lumbar Spinal Stenosis
Study Comparing 3 Different Treatments for Arthritis of the Lower Back (Lumbar Spinal Stenosis)
BACKGROUND: Lumbar spinal stenosis - known by patients as "arthritis of the spine" - is a condition that is very common; found in about 30% of older adults.
- Trial name
- NCT01943435
- Testing
- NSAIDs; adjunctive analgesics; adjunctive anti-depressants, Lumbar epidural injection, Joint Mobilizations (spine, sacroiliac, hip)
- Where
- United States
- Volunteers
- 259 people
- Sponsor
- Michael Schneider, DC, PhD
Lumbar Disc Herniation
Telerehabilitation After Lumbar Disc Herniation Surgery
This randomized controlled trial evaluated the effectiveness of a telerehabilitation-based exercise program in individuals who had undergone surgery for lumbar disc herniation.
- Trial name
- NCT07889817
- Testing
- Home Exercise Program, Telerehabilitation-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Hasan Kalyoncu University
Pain, Postoperative, Anesthesia, Regional
Comparison of the Efficiency of PENG Block and ESP Block Used for Postoperative Analgesia in Elective Hip Surgery
The aim of the study is to determine whether the traditional intravenous analgesia technique or the ultrasound-guided pericapsular nerve group block or the unilateral erector spina plane block technique is superior in…
- Conditions
- Pain, Postoperative, Anesthesia, Regional, Hip Surgery, Ultrasound-Guided
- Trial name
- NCT05802589
- Testing
- Lumbar Erector Spinae Plane Block, Pericapsular Nerve Group Block, no peripheral block
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Trakya University
Lumbar Disc Herniation, Postoperative Pain
Comparison of the Effects of Quadratus Lumborum Block and Retrolaminar Block on Postoperative Pain in Lumbar Disc Herniation Surgery
This study aims to compare the analgesic efficacy of quadratus lumborum block (QLB) and retrolaminar block (RLB) in patients undergoing lumbar disc herniation surgery.
- Trial name
- NCT07166250
- Testing
- Quadratus Lumborum Block, Retrolaminar Block
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Kocaeli University
Hip Surgery
Comparison Between 2 Techniques for Lumbar-ESPB
Diffusion of local anesthetics after a lumbar ESPB within fascial planes towards nerve structures is a matter of debate. The main objective of the study is to compare the incidence of sensory block between two techniques of…
- Trial name
- ESPTA (NCT07104097)
- Testing
- spinal anesthesia, superficial erector spinal plane block (ESPB), deep (inter laminar) erector spinal plane block (ESPB)
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Papa Giovanni XXIII Hospital
Lumbar Spinal Stenosis
Targeted Nutritional Supplement After Lumbar Spine Surgery: A Randomized, Placebo-Controlled, Double-Blind Trial
The goal of this clinical trial is to prospectively evaluate the effects of essential amino acid (EAA) supplementation on the volume and structure of the muscles surrounding the spine (paraspinal musculature).
- Trial name
- NCT06579391
- Testing
- Essential amino acids, Alanine
- Where
- United States
- Sponsor
- University of California, Irvine
Cervical Spondylosis, Lumbar Spondylosis
Safety and Efficacy of Pre-incisional Intravenous Ibuprofen to Reduce Postoperative Pain and Opioid Dependence After Posterior Cervical or Lumbar Instrumented Spine Surgery
A prospective, randomized, placebo controlled, double-blinded study at a single institution.
- Trial name
- NCT02276911
- Testing
- Ibuprofen, normal saline
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Lumbar Herniated Intervertebral Disc
Biportal Endoscopic Discectomy Versus Microdiscectomy: RCT, Non-inferiority Trial
This study is to compare the clinical outcome between the biportal endoscopic discectomy and microdiscectomy in herniated intervertebral disc of lumbar spine
- Trial name
- BESS (NCT03924700)
- Testing
- Biportal endoscopy, Microdiscectomy
- Where
- 2 sites in South Korea
- Volunteers
- 64 people
- Sponsor
- Seoul National University Hospital