Clinical trials: Lumbar Surgery
Lumbar Disc Herniation, Spinal Surgery
Comparison of 5 vs 8 cmH₂O PEEP on Respiratory Mechanics in Prone Lumbar Surgery
This randomized controlled clinical trial aims to compare the effects of two different positive end-expiratory pressure (PEEP) levels (5 cmH₂O and 8 cmH₂O) on respiratory mechanics in patients undergoing lumbar spine surgery in…
- Conditions
- Lumbar Disc Herniation, Spinal Surgery, Prone Position, General Anesthesia
- Trial name
- PROPEEP (NCT07545733)
- Testing
- Mechanical Ventilation (PEEP)
- Volunteers
- 60 people
- Sponsor
- Harran University
Obesity & Overweight, Lumbar Spine Surgery
Sevoflurane vs Propofol Anesthesia in Obese Patients Undergoing Lumbar Surgery
This randomized, single-center, single-masked clinical trial aims to compare the immunomodulatory effects of sevoflurane-based inhalational anesthesia and propofol-based total intravenous anesthesia in obese patients undergoing…
- Trial name
- NCT07611240
- Testing
- Propofol (Astra-Zeneca), Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ataturk University
Spinal Stenosis Lumbar
Effect of Paravertebral Muscle Fat Infiltration on Rocuronium Use in Lumbar Surgery
To investigate the effect of different degrees of fat infiltration on rocuronium use in lumbar surgery was monitored by trapezius muscle relaxation.
- Trial name
- RUILS (NCT05619848)
- Testing
- Rocuronium Bromide
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Zheng Guo
Spondylolisthesis, Lumbar Region, Spinal Trauma With Neurological Deficit
Adult Patient Outcomes After Spine Surgery With Fibergraft BG Putty/Viper Prime
The Viper Prime/Expedium spine systems are intended to provide immobilization and stabilization of spinal segments in skeletally mature patients as an adjunct to fusion in the treatment of acute and chronic instabilities or…
- Conditions
- Spondylolisthesis, Lumbar Region, Spinal Trauma With Neurological Deficit, Degeneration of Lumbar Intervertebral Disc
- Trial name
- NCT06704906
- Testing
- Use of Viper Prime/Expedium system with Fibergraft BG Putty
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Nitin Agarwal
Degeneration, Spinal Stenosis
Vertebropexy - Randomized-controlled Trial
To assess the need for additional fusion surgery versus the risk of a revision surgery in patients with degenerative lumbar spinal disease and to assess efficacy and risk of the ligamentous fixation technique (vertebropexy)
- Conditions
- Degeneration, Spinal Stenosis, Fusion of Spine
- Trial name
- VPRCT (NCT06024785)
- Testing
- Vertebropexy
- Where
- Switzerland
- Volunteers
- 164 people
- Sponsor
- Balgrist University Hospital
Osteoporosis, Fusion of Spine, Lumbar Region
Preoperative Teriparatide Use on Insertional Torque of Pedicle Screws for Lumbar Fusion Surgery
This project aims to investigate any difference of insertional torque strength for osteoporotic patients with preoperative 1-month teriparatide injections versus those without.
- Trial name
- NCT03770338
- Testing
- Teriparatide
- Where
- 3 sites in Hong Kong
- Volunteers
- 192 people
- Sponsor
- The University of Hong Kong
Lumbar Spinal Degeneration
Analysis of Three-Dimensional Navigated Lateral Lumbar Interbody Fusion
This observational study evaluates the clinical outcomes and procedural characteristics of navigation-assisted oblique lumbar interbody fusion (OLIF) in patients with lumbar degenerative disease.
- Trial name
- NCT07437118
- Where
- Taiwan
- Volunteers
- 11 people
- Sponsor
- MengTingWu
Lumbar Radiculopathy
Effects of a Prehabilitation Program in Patients Undergoing Lumbar Radiculopathy Surgery
The purpose of the following study is to analyze the effects of a prehabilitation program based on therapeutic exercise, back care education and pain neuroscience education through the visualization of videos, compared to…
- Trial name
- NCT06145620
- Testing
- Physiotherapy
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Cardenal Herrera University
Lumbar Surgery
Assessment of the Nociception During Lumbar Surgery
The aim of the study is to assess the accuracy of a new paradigm in measuring the level of nociception during lumbar surgery. The paradigm is based the measurement of the baroreflex in response to noxious stimuli in anesthetized…
- Trial name
- CARDEAN-2 (NCT01015651)
- Testing
- remifentanil
- Where
- France
- Volunteers
- 16 people
- Sponsor
- University Hospital, Grenoble
Hip Surgery, Post Operative Pain Control
Post Operative Pain Control After Pediatric Hip Surgery
Hip surgery in children is painful and the optimal modality for managing post-operative pain has not been established. This prospective randomized controlled trail compares lumbar plexus catheter (LPC), lumbar epidural catheter…
- Trial name
- NCT03435692
- Testing
- Lumbar Plexus Catheter, Lumbar Epidural Catheter, Patient Controlled Analgesia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Foraminal Stenosis
Comparative Outcomes of Conventional TLIF With Posterior Decompression Surgery Versus Endoscopic Foraminotomy Surgery
Comparative Outcomes of Conventional Transforaminal Lumbar Interbody Fusion With Posterior Decompression Surgery Versus Endoscopic Foraminotomy Surgery in Stable Lumbar Foraminal Stenosis An Ambi-directional Cohort Study
- Trial name
- TLIF (NCT06685575)
- Testing
- Endoscopic Foraminotomy Surgery
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Degenerative Lumbar Spine Diseases, Lumbar Spinal Instability
Role of Intraoperative Computed Tomography in Assessment of Spine Instability in Lumbar Degenerative Disease
This study examines how well computed tomography (CT) imaging performed during spine surgery - known as intraoperative CT - can detect instability in the lower (lumbar) part of the spine.
- Conditions
- Degenerative Lumbar Spine Diseases, Lumbar Spinal Instability, Degenerative Spondylolisthesis, Lumbar Spinal Stenosis
- Trial name
- INSIGHT-CT (NCT07644507)
- Testing
- Intraoperative Computed Tomography (O-arm)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
Back Pain, Fusion of Spine, Lumbar Region
The Comparison of Postoperative Pain After Lumbar Fusion Surgery in Intravenous Patient-controlled Analgesia Between Conventional Mode and Optimizing B.I Mode With 'PAINSTOP' Equipment
The postoperative pain of lumbar fusion surgery is very severe that it is necessary to use additional analgesics as well as a patient controlled analgesia (PCA).
- Conditions
- Back Pain, Fusion of Spine, Lumbar Region, Spinal Stenosis
- Trial name
- NCT03047044
- Testing
- Optimizing basal infusion (B.I), Conventional PCA mode
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Lumbar Spine Disease
Management of Perioperative Pain Using Erector Spinae Plane Block in Open Microscopic Lumbar Surgery
The aim of this study is to compare patients receiving bilateral erector spinae block with ropivacaine vs control group in terms of pain score, total opioid consumption, hemodynamic changes intraoperatively, length of…
- Trial name
- NCT06270654
- Testing
- Erector spinae plane block, Skin infiltration LA
- Where
- Malaysia
- Volunteers
- 40 people
- Sponsor
- University of Malaya
Lumbar Spinal Stenosis
Minimal Invasive Surgery Versus Interlaminar Decompression in Lumbar Canal Stenosis
Conventional open surgery has been shown to be an effective procedure for LCS decompression. Minimally invasive surgery (MIS) through tubular retractors is a recently introduced alternative procedure for decompression of LCS.
- Trial name
- NCT05147064
- Testing
- minimally invasive surgery, conventional open surgery
- Volunteers
- 40 people
- Sponsor
- Assiut University
Investigate the Effect of External Lumbar Cistern Drainage in Preventing Postoperative Hydrocephalus in Patients Who Have Undergone Meningioma Surgery
Impact of External Drainage of the Lumbar Cistern in Patients With Hydrocephalus Following Meningioma Surgery and Its Influence on Patient Satisfaction
This study aims to investigate the effect of external lumbar cistern drainage in preventing postoperative hydrocephalus in patients who have undergone meningioma surgery and its impact on patient satisfaction.
- Trial name
- NCT06383169
- Where
- China
- Volunteers
- 86 people
- Sponsor
- First Hospital of Zhangjiakou City
Lumbar Disc Herniation Surgery
Virtual Reality Operating Room Tour and Preoperative Anxiety in Spinal Surgery Patients Experimental: "VR Operating Room Tour" - Participants Viewed a Five-minute Virtual Reality Video of Preoperative Preparation and the Operating Room the Night Before Surgery, Facilitated by a Nurse.
This randomised controlled trial evaluated whether a nurse-facilitated virtual reality (VR) tour of the operating room reduces preoperative anxiety in adults awaiting lumbar disc herniation surgery.
- Trial name
- VROOM (NCT07778030)
- Testing
- Virtual Reality Operating Room Tour
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Zonguldak Bulent Ecevit University
Lumbar Disc Herniation
THE EFFECT OF RELAXATION EXERCİSE ON COMFORT AND ANXIETY IN HERNIATED LUMBAR DISC SURGERY
This study aimed to investigate the effect of progressive relaxation exercises on the comfort and anxiety levels of patients undergoing lumbar disc herniation surgery in the neurosurgery clinic.
- Trial name
- NCT06688773
- Testing
- Progressive relaxation exercise, Control group: Standart nursing care group
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Bandırma Onyedi Eylül University
Pain and Anxiety in Patients Undergoing Surgery for Lumbar Laminectomy.
Perioperative Melatonin in Lumbar Laminectomy
Patients undergoing lumbar laminectomy surgery will receive either 5 or 10 mg melatonin or placebo once the evening before surgery and again 90 minutes before surgery.
- Trial name
- NCT01126294
- Testing
- 5 mg melatonin, 10 mg melatonin
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University Health Network, Toronto
Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain
Determining the Prognostic Value of Continuous Intrathecal Infusion
The purpose of this study will be to determine the efficacy and the prognostic value of a continuous intrathecal prognostic infusion test in an in-hospital setting for selecting patients who would have better long term outcomes…
- Conditions
- Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain, Vertebral Compression Fracture, Failed Back Surgery Syndrome
- Trial name
- NCT03523000
- Testing
- Continuous intrathecal prognostic infusion test, Bupivacaine, Fentanyl
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University Hospitals Cleveland Medical Center