Clinical trials: Lumbar Surgery
Lumbar Spinal Stenosis
Effect of the Posterior Ligamentous Complex on the Adjacent Segments Degeneration After Lumbar Surgery
To investigate whether destroying the adjacent posterior ligamentous complex (PLC) has an effect on adjacent segment degeneration (ASD) after L5/S1 posterior lumbar interbody fusion (PLIF)
- Trial name
- NCT04946487
- Testing
- total laminectomy
- Volunteers
- 80 people
- Sponsor
- Peking University Third Hospital
Lumbar Disc Herniation
An mTLIP Block for Analgesia Management After Lumbar Spinal Surgery.
Pain management is an important issue following lumbar spinal surgery. Wound infiltration is a technique that a local anesthetic solution is infiltrated into the tissues around the surgical area.
- Trial name
- NCT03967314
- Testing
- TLIP block group (group T), Wound infiltration group (group W)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Spondylolisthesis, Analgesia, Postoperative
Ultrasound-Guided Erector Spinae Plane Block for Postoperative Pain Control in Lumbar Spondylolisthesis Surgery
This clinical trial aims to evaluate the effectiveness of ultrasound-guided erector spinae plane (ESP) block as an adjunct to general anesthesia for managing postoperative pain in patients undergoing lumbar spondylolisthesis…
- Conditions
- Spondylolisthesis, Analgesia, Postoperative, ESPB
- Trial name
- NCT07514806
- Testing
- Control Group: General Anesthesia Without Erector Spinae Plane Block, Intervention Group: General Anesthesia With Ultrasound-Guided Erector Spinae Plane Block
- Where
- Bangladesh
- Volunteers
- 50 people
- Sponsor
- Bangladesh Medical University
Intervertebral Disc Degeneration
Prospective Study of Safety and Efficacy of InQu® Bone Graft Extender in Lumbar Interbody Fusion Surgery
The purpose of this study is to collect on-label safety and efficacy data where InQu Bone Graft Extender is applied to transforaminal lumbar interbody fusion (TLIF) and posterior lumbar interbody fusion (PLIF).
- Trial name
- Intebody (NCT02400762)
- Where
- 2 sites in United States
- Volunteers
- 130 people
- Sponsor
- ISTO Technologies, Inc.
Intervertebral Disc Prolapse
Pregabalin Compared to Gabapentin for Pain Control in Lumbar Disc Surgery
Pregabalin is claimed to have superior analgesic effect at lower doses and better pharmacological profile as compared to gabapentin esp. in perioperative pain control after major surgeries like intervertebral disc surgery.
- Trial name
- NCT02120703
- Testing
- Pregabalin, Gabapentin
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Aga Khan University
Sciatica, Intervertebral Disk Displacement
Manipulation or Microdiscectomy For Sciatica? A Prospective Randomized Controlled Trial.
The purpose of this study was to compare standardized chiropractic treatment (spinal manipulation) to back surgery (microdiscectomy) for patients with sciatica secondary to lumbar herniated disc refractory to medical management.
- Trial name
- NCT00415220
- Testing
- Spinal Manipulation, Microdiscectomy
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- McMorland, Gordon, D.C.
To Compare Efficacy of Dexmedetomidine in Bilateral Quadratus Lumborum vs Lumbar Epidural Blocks on Analgesia After Major Lower Abdominal Surgery
Clinical Efficacy and Safety of Dexmedetomidine as an Adjuvant in Quadratus Lumborum Versus Epidural Block in Postoperative Lower Abdominal Cancer Surgeries
Clinical efficacy and safety of dexmedetomidine as an adjuvant in quadratus lumborum versus epidural block in postoperative patients
- Trial name
- NCT06130670
- Testing
- nerve block
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Assiut University
Analgesia
Peroperative Effect of Regional Anesthesia in Hip Surgery
A total of 120 patients scheduled for surgical operation due to hip fracture were divided into two randomized groups. The first group received pericapsular nerve group (PENG) block, while the second group received lumbar erector…
- Trial name
- NCT05960253
- Testing
- Pericapsular Nerve Group Block, Lumber Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Isthmic Spondylolisthesis
Anterior vs Posterior Surgery for Lumbar Isthmic Spondylolisthesis
Currently there is no consensus on the best surgical treatment of patients with symptomatic isthmic spondylolisthesis (IS). Clinical equipoise exists amongst experienced clinicians on the various surgical techniques available.
- Trial name
- NCT05701046
- Testing
- Interbody fusion surgery
- Where
- Canada
- Volunteers
- 489 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Lumbar Spinal Stenosis
Long-term Evolution of Patients Suffering From Lumbar Canal Stenosis and Supported by Minimally Invasive Surgery: SUIVISTENO
describe the functional evolution of patients at more than 10 years post intervention. describe the evolution of pain, satisfaction, quality of life of patients to more than 5 years pot intervention.
- Trial name
- SUIVISTENO (NCT04124146)
- Testing
- MRI for some patients according functionnal tests results
- Volunteers
- 100 people
- Sponsor
- Centre Medico-Chirurgicale et Obstetrique Cote d'Opale
Surgical Wound, Herniation
Efficacy of a Full-Thickness Placental Allograft in Lumbar Microdiscectomy
To evaluate the efficacy of full thickness placental allograft use in Microdiscectomy application. To evaluate post-microdiscectomy reherniation rate in patients treated with full-thickness placental allografts.
- Trial name
- NCT03536013
- Testing
- Other: Full-thickness placental allograft
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- StimLabs
Fusion of Spine, Lumbar Region, Anesthesia, Local
Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery
The purpose of this study is to determine if the method for injecting local anesthesia affects patients' pain and opioid usage after surgery.
- Conditions
- Fusion of Spine, Lumbar Region, Anesthesia, Local, Pain, Postoperative, Opioid Use
- Trial name
- NCT06528288
- Testing
- Erector Spinae Plane Block, Subcutaneous Anesthesia
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Massachusetts, Worcester
Lumbar Fusion Surgery, Fusion of Joint
Evaluation of the Efficacy and Safety of Absorbable vs Traditional Bone Wax for Facet Fusion After Lumbar Fusion Surgery
Hemorrhage on the surface of cancellous bone presents a significant challenge in orthopedic surgery. Traditional bone wax, commonly utilized for hemostasis in bone wounds, is non-absorbable and associated with various…
- Trial name
- NCT07040293
- Testing
- Absorbable bone wax for hemostasis in the osteotomy surface of the facet joint, Traditional bone wax for hemostasis in the osteotomy surface of the facet joint
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Shanghai Changzheng Hospital
Lumbar Disc Herniation
Trial to Show Non-inferiority / Superiority of an Endoscopic Transforaminal Discectomy to Standard Microdiscectomy
This study compares an endoscopic transforaminal surgical technique for the treatment of a herniated disc to the standard microsurgical procedure. Clinical parameters as well as health economy will be assessed.
- Trial name
- TESCORT (NCT01622413)
- Testing
- joimax TESSYS, Microdiscectomy
- Where
- 3 sites in Austria, Germany
- Sponsor
- Joimax GmbH
Percutaneous Pedicular Screw (PPS) Fixation, Minimally Invasive Transforaminal Lumbar Interbody Fusion (MIS TLIF) Surgeries
Comparison of Thoracolumbar Interfascial Plane Block (TLIP-block) and Local Anesthetic (LA) Infiltration in Minimally Invasive Spine Surgery: A Randomized Controlled Trial
The goal of this clinical trial is to compare the effectiveness of the thoracolumbar interfascial plane block (TLIP block) versus local anesthetic (LA) infiltration in managing postoperative pain in minimally invasive surgery…
- Trial name
- NCT06761079
- Testing
- Thoracolumbar interfascial plane block, Local anesthetic infiltration
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Physical Capability Outcomes
Physical Capability Outcomes After Single-Level PD-L vs Single-Level ALIF: a Multi-Center Clinical Trial
The purpose of this study is to compare the physical capability outcomes of patients who undergo single-level ProDisc-L disc replacement with those of patients who undergo stand-alone, single-level anterior lumbar interbody…
- Trial name
- NCT01055574
- Where
- 6 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gundersen Lutheran Medical Foundation
Postoperative Pain, Femur Fracture
Comparing Suprainguinal Fascia Iliaca Block With Erector Spinae Plane Block in Hip and Proximal Femur Surgery
Most hip fractures occur in the elderly population. Opioid-related respiratory depression is more common in the elderly population but can cause severe brain damage or death.
- Conditions
- Postoperative Pain, Femur Fracture, Regional Anesthesia
- Trial name
- NCT05642975
- Testing
- Regional Block Comparison
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lumbar Disc Surgery, Post Operative Pain
Kinesio Taping in Patients After Lumbar Disc Surgery
In this study, it will be determined whether Kinesio-tape is an effective and reliable application in reducing pain and maintaining functionality after lumbar disc surgery, and its effect on the rehabilitation process will be…
- Trial name
- NCT05476718
- Testing
- Kinesio taping
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Mersin University
Radiculopathy
Presentation of Lumbar Disc and Reduction of Symptoms
The trial aims to assess the hypothesis that presentation of the disc material to the patient following a lumbar microdiscectomy would positively influence the improvement in their leg and back symptoms.
- Trial name
- POLDAROS (NCT00440856)
- Testing
- Presentation of excised intervertebral disc fragments
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Dural Tear, Bedrest
Symptom Prevalence and Severity in Lumbar Spine Surgery With and Without Dura Rupture
The primary purpose of this study is to assess whether lumbar spine surgery patients with dura rupture differ in symptom prevalence and severity from other lumbar spine surgery patients in the early postoperative phase.
- Conditions
- Dural Tear, Bedrest, Lumbar Spine Surgery
- Trial name
- NCT04794166
- Where
- Denmark
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet