Clinical trials: Lung; Node
Lung Neoplasms, Neoplasm Metastasis
Mediastinal Lymph Node Dissection in Conjunction With Pulmonary Metastasectomy From Colorectal Cancer
To study whether or not total mediastinal lymph node dissection in conjunction with pulmonary metastasectomy from colorectal cancer is associated with improved survival compared to pulmonary metastasectomy only.
- Conditions
- Lung Neoplasms, Neoplasm Metastasis, Colorectal Cancer
- Trial name
- NCT03113318
- Testing
- Total mediastinal lymph node dissection and pulmonary metastasectomy, Only pulmonary metastasectomy
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Atrial Fibrillation, Left Atrial Dilatation
His-pacing and AV-node Ablation vs. Pulmonary Vein Isolation for Atrial Fibrillation
Objective To investigate if conduction system pacing ((CSP) i.e. atrioventricular node ablation + His bundle pacing or Left Bundle Branch pacing) is as good as (or better than) atrial fibrillation ablation with pulmonary vein…
- Trial name
- His-PAAF (NCT04512586)
- Testing
- Conduction System pacing and AV node ablation, Atrial fibrillation ablation by pulmonary vein isolation
- Where
- 4 sites in Sweden
- Volunteers
- 45 people
- Sponsor
- Region Skane
Sentinel Lymph Node
Bronchial NIR Image-guided Resection
This is a clinical trial to evaluate the use of peritumoral injection of near-infrared dye indocyanine green to identify lung lesions and sentinel lymph nodes.
- Trial name
- NCT03097575
- Testing
- ICG Intervention, Near Infrared Imaging
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Lung Lesions, Mediastinal and Hilar Lymph Node Enlargement
A Study of Contrast-enhanced EBUS in Lung Lesions and Intrathoracic Lymph Nodes
Exploring the Clinical Application Value of Contrast Enhancement Features in CE-EBUS Images for the Diagnosis of Pulmonary Lesions and Intrapulmonary Lymph Nodes
- Trial name
- NCT07060378
- Testing
- Contrast-enhanced endobronchial ultrasound
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Shanghai Chest Hospital
Cancer
OX-40 Protein Expression in the Sentinel Lymph Nodes of Patients With Cancer
RATIONALE: Studying protein expression in sentinel lymph node tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
- Trial name
- NCT00900302
- Testing
- protein expression analysis, immunohistochemistry staining method, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- OHSU Knight Cancer Institute
Mediastinal Lymphadenopathy, Non-small Cell Lung Carcinoma
Optical Biopsy for Thoracic Lymph Nodes.
EUS-FNA is the recommended diagnostic examination of choice when patients present with suspected lower mediastinal lymph nodes on imaging.
- Conditions
- Mediastinal Lymphadenopathy, Non-small Cell Lung Carcinoma, Sarcoidosis
- Trial name
- NCT02689050
- Testing
- Needle based confocal laser endomicroscopy (nCLE)
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Tuberculosis, Tuberculosis, Pulmonary
Shortened Regimen for Drug-susceptible TB in Children
While drug-susceptible tuberculosis (TB) disease in children currently requires four to six months of treatment, most children may be able to be cured with a shorter treatment of more powerful drugs.
- Conditions
- Tuberculosis, Tuberculosis, Pulmonary, Tuberculosis, Lymph Node, Mycobacterium Tuberculosis
- Trial name
- SMILE-TB (NCT06253715)
- Testing
- Isoniazid, Rifampin, Pyrazinamide
- Where
- 9 sites in India, Indonesia and 5 more
- Volunteers
- 860 people
- Sponsor
- Johns Hopkins University
Anatomic Stage IV Breast Cancer American Joint Committee on Cancer (AJCC) v8, Metastatic Breast Carcinoma
Testing Whether Treating Breast Cancer Metastases With Surgery or High-Dose Radiation Improves Survival
This randomized phase II/III trial studies how well standard of care therapy with stereotactic radiosurgery and/or surgery works and compares it to standard of care therapy alone in treating patients with breast cancer that has…
- Conditions
- Anatomic Stage IV Breast Cancer American Joint Committee on Cancer (AJCC) v8, Metastatic Breast Carcinoma, Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Neoplasm in the Liver
- Trial name
- NCT02364557
- Testing
- Stereotactic Body Radiotherapy, Surgery
- Where
- 162 sites in United States, Canada and 2 more
- Volunteers
- 129 people
- Sponsor
- NRG Oncology
Lung Disease, Inflammation
Study of Biologic Materials From the Mediastinal Lymph Nodes From Patients With Lung Disease.
The purpose of this protocol is to obtain biologic materials from the mediastinal lymph nodes from patients with lung disease and mediastinal lymph node involvement in order to: (1) develop a better understanding of the cause and…
- Conditions
- Lung Disease, Inflammation, Lung Cancer, Sarcoidosis
- Trial name
- NCT02168036
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Weill Medical College of Cornell University
Lung Cancer, Lung; Node
Molecular Analysis of Endoscopic Cytology Samples Supernatant in Pulmonary Nodules
Lung cancer screening is based on low dose CT scan (LDCT), a highly sensitive but poorly specific tool. Complementary specific approaches are thus strongly needed, among which cell-free DNA (cfDNA) genotyping has been proven…
- Trial name
- KOBE (NCT05306912)
- Testing
- Blood samples
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Toulouse
Lung Cancer
Significance of Ultrasound Elastography in Lymph Node
Background and Objectives: Elastography can reflect the difference of tissue hardness, which helps to identify the difference of hardness between benign and malignant tissues.
- Trial name
- NCT03391557
- Testing
- UE
- Volunteers
- 42 people
- Sponsor
- Fangsurong
Lung Cancer
Minimally Invasive, Diagnosis and Staging of Lung Cancer
The gold standard techniques to assess the extent of disease and decide on therapy for patients with lung cancer consists of cervical mediastinoscopy, which is a surgical procedure which entails an incision in the neck and the…
- Trial name
- NCT01011595
- Testing
- Cervical Mediastinoscopy, Endobronchial Ultrasound (EBUS), Endoscopic Ultrasound (EUS)
- Where
- Canada
- Volunteers
- 166 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Non-Small Cell Lung Cancer, Lymph Node Metastasis
XR-Assisted PET/CT Navigation for Cervical Lymph Node Dissection in Lung Cancer
This single-arm, prospective feasibility study evaluates an Extended Reality (XR) headset-based preoperative surgical planning workflow that fuses 18F-FDG PET metabolic hotspots with CT anatomy on the OpVerse platform, in…
- Conditions
- Non-Small Cell Lung Cancer, Lymph Node Metastasis, Supraclavicular Lymph Node Metastasis
- Trial name
- XR-NeckLND (NCT07593872)
- Testing
- OpVerse XR Surgical Planning Platform with HoloLens HMD, Cervical / Supraclavicular Lymph Node Dissection
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Lung Cancer With Mediastinal Lymph Node Involvement
Methylation Level of SHOX2 in Endobronchial Ultrasound With Real-time Guided Transbronchial Needle Aspiration for Lung Cancer Staging
A DNA hypermethylation of the gene locus SHOX2 can be frequently found in lung cancer tissue. The purpose of this study is to determine whether the assessment of the hypermethylation level of SHOX2 in specimens obtained by…
- Trial name
- NCT01653002
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital, Essen
Lung Cancer
Incidence of SCLN Metastasis in Patients Referred for EBUS-TBNA
Evaluation of the anatomic extent of a primary lung cancer and presence of metastasis are essential for selection of an appropriate management strategy.
- Trial name
- NCT03087305
- Testing
- Supraclavicular lymph node ultrasound
- Where
- United States
- Sponsor
- University of Minnesota
Non-Small Cell Lung Cancer
Station 4L Lymph Node Dissection Versus No Dissection in Clinical Stage I Solid Nodule-Type Invasive NSCLC
This multicenter, prospective, randomized clinical trial will enroll adults aged 18 to 75 years with resectable clinical stage I (T1-T2aN0M0) invasive non-small cell lung cancer presenting as a single solid nodule…
- Trial name
- NCT07801430
- Testing
- Station 4L Lymph Node Dissection
- Where
- China
- Volunteers
- 384 people
- Sponsor
- Fudan University
Atrial Fibrillation, Atrial Flutter
Feasibility Study for Optically Guided Radiofrequency Ablation Catheter
Clinical study intended to evaluate the feasibility of a new irrigated RF ablation catheter that allows the physiologist to perform a regular RF ablation procedure while it is being monitored through an imaging technique known as…
- Trial name
- NEOVIEW (NCT03589742)
- Testing
- AblaView® Ablation Catheter
- Where
- Czechia
- Volunteers
- 4 people
- Sponsor
- Medlumics
Mediastinal Lymphadenopathy, Hilar Lymphadenopathy
Conventional Versus Ultrasound-guided Transbronchial Needle Aspiration for the Diagnosis of Hilar/Mediastinal Lymphadenopathies
The main purpose of the present study is to assess whether the sensitivity of Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) is superior to that of conventional TBNA in the diagnosis of hilar/mediastinal…
- Conditions
- Mediastinal Lymphadenopathy, Hilar Lymphadenopathy, Lymphoma, Lung Neoplasms
- Trial name
- NCT01658280
- Testing
- EBUS-TBNA
- Where
- Italy
- Volunteers
- 253 people
- Sponsor
- Azienda Ospedaliero, Universitaria Ospedali Riuniti
Giant Cell Arteritis, Takayasu's Arteritis
Reproductive Health in Men and Women With Vasculitis
The purpose of this study is to learn about reproductive health, including fertility and pregnancies, in people with vasculitis.
- Conditions
- Giant Cell Arteritis, Takayasu's Arteritis, Polyarteritis Nodosa, Wegener's Granulomatosis
- Trial name
- NCT02176070
- Where
- United States
- Volunteers
- 467 people
- Sponsor
- University of South Florida
Lung Cancer
Characteristics of Mediastinal Lymph Node With False Positive FDG PET/CT Results in Lung Cancer Staging : Relation With TB and Latent TB Infection
The purpose of this study is to analyze pathologic and radiologic characteristics of mediastinal lymph nodes with false positive FDG PET/CT results in lung cancer staging and assess relationship between false positive mediastinal…
- Trial name
- NCT01376856
- Where
- South Korea
- Volunteers
- 33 people
- Sponsor
- Yonsei University