Clinical trials: Lung; Node
Lung Cancer, Lymph Nodes
Transbronchial Needle Forceps for Endobronchial Ultrasound
Prove the feasibility of a needle forceps in patients with enlarged mediastinal lymph nodes
- Trial name
- NCT01145924
- Testing
- EBUS TBNF
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Heidelberg University
Hilar Cholangiocarcinoma, Intrahepatic Cholangiocarcinoma (Icc)
Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma (POELH-III)
In the POELH-II trial (Clinicaltrials.gov ID NCT05678218) patients with presumed resectable perihilar (pCCA), intrahepatic (iCCA) or mid-common bile duct (CBD) cholangiocarcinoma had the outcomes of their preoperative endoscopic…
- Conditions
- Hilar Cholangiocarcinoma, Intrahepatic Cholangiocarcinoma (Icc), Cholangiocarcinoma, Perihilar Cholangiocarcinoma
- Trial name
- POELH-III (NCT07161869)
- Testing
- Registration of all findings during preoperative Endoscopic Ultrasound
- Where
- 6 sites in Netherlands
- Volunteers
- 250 people
- Sponsor
- Erasmus Medical Center
NSCLC (Non-small Cell Lung Cancer), Artificial Intelligence (AI)
Artificial Intelligence-based Model for the Prediction of Occult Lymph Node Metastasis and Improvement of Clinical Decision-making in Non-small Cell Lung Cancer
This nationwide, multicenter observational study aims to develop and validate a multimodal artificial intelligence (AI) model for detecting occult lymph node metastasis in early-stage non-small cell lung cancer (NSCLC) patients.
- Conditions
- NSCLC (Non-small Cell Lung Cancer), Artificial Intelligence (AI), Lymphnode Metastasis
- Trial name
- NCT06684418
- Testing
- chest enhanced CT
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Fudan University
Lymphadenopathy
Comparison of Endobronchial Ultrasound-Guided Biopsy Using Fine Needle Aspiration Versus Fine Needle Capillary Sampling
Primary objective: To estimate the degree of agreement in diagnosis of cytologic samples from mediastinal lymph nodes obtained by Endobronchial Ultrasound (EBUS)-guided Fine Needle Capillary Sampling (FNC) versus Fine Needle…
- Trial name
- NCT00886847
- Testing
- Lymph Node Needle Tissue Collections
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- M.D. Anderson Cancer Center
Lung Cancer, Stage IIIA-cN2
Molecular Signature From Tumor to Lymph Nodes
Mediastinal lymph node (LN) involvement (N2) in non-small cell lung cancer (NSCLC) concerns 15% of resectable tumors and is associated with a poor prognosis and an overall survival reaching 9 to 49%.
- Conditions
- Lung Cancer, Stage IIIA-cN2, Operated With Curative Intent, Primary Tumor Tissue Available
- Trial name
- N2-3S (NCT04677205)
- Where
- 12 sites in France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lung; Node
Diagnosis of Peripheral Lung Nodules Using Cryobiopsy
Since the traditional radial endobronchial ultrasound guided biopsy technique of solitary pulmonary nodules using the forceps has several shortcomings, the purpose of this study is to investigate a new biopsy technique using the…
- Trial name
- Cryo-Nodule (NCT04885595)
- Testing
- Forceps biopsy and cryobiopsy
- Where
- Switzerland
- Volunteers
- 54 people
- Sponsor
- University of Zurich
Lung Cancer
Use of Harmonic Scalpel to Decrease Lymphatic and Chest Tube Drainage After Lymph Node Dissection With Lobectomy.
In an effort to elucidate whether the Harmonic Scalpel will improve sealing lymphatics and decrease lymphatic drainage thereby decreasing the length of time that chest tubes are required and minimizing length of stay; the…
- Trial name
- NCT00591552
- Testing
- Harmonic ACE23P Scalpel, Electrocautery
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Sentara Cardiovascular Research Institute
Lung Cancer, Lung; Node
Prospective rAndomized sTudy efficaCy tHree-dimensional rEconstructions Segmentectomy
With this project we want to study the effectiveness of 3D reconstruction of preoperative CT to reduce operating times, blood loss and conversions after segmentectomy performed in thoracoscopy / robotics.
- Trial name
- PATCHES (NCT05716815)
- Testing
- CT scans 2D Reconstruction, CT scans 2D plus 3D Reconstruction
- Volunteers
- 288 people
- Sponsor
- Ospedale Centrale Bolzano
Lung Adenocarcinoma, Stage I
Improving the Intraoperative Diagnosis Accuracy of Invasiveness for Small-sized Lung Adenocarcinoma
The goal of this observational study is to improve the intraoperative diagnosis accuracy of invasiveness for small-sized lung adenocarcinoma by combining multi-modal information.
- Trial name
- NCT05830812
- Testing
- Invasiveness diagnosis
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Artificial Intelligence, Endobronchial Ultrasound
Augmented Endobronchial Ultrasound (EBUS-TBNA) With Artificial Intelligence
To evaluate the usefulness of Deep neural network (DNN) in the evaluation of mediastinal and hilar lymph nodes with Endobronchial ultrasound (EBUS).
- Conditions
- Artificial Intelligence, Endobronchial Ultrasound, Lung Cancer
- Trial name
- NCT05739331
- Testing
- machine learning algorithm
- Where
- 2 sites in Norway
- Volunteers
- 50 people
- Sponsor
- Norwegian University of Science and Technology
NSCLC, Stage IV
Early Response Evaluation in NSCLC Patients Treated With Immunotherapy
A pilot study with biomarker exploration.50 patients with stage IV non-small cell lung cancer (NSCLC) that are eligible for treatment with nivolumab.
- Trial name
- NCT04082988
- Testing
- 18F-FDG PET-CT
- Where
- 2 sites in Netherlands
- Volunteers
- 9 people
- Sponsor
- The Netherlands Cancer Institute
Lung Cancer, Lung; Node
Diagnostic Yeld of Ultrathin Bronchoscopy in Peripheral Pulmonary Lesions
The use of an ultrathin bronchoscope (UB) has recently been introduced in the diagnosis of peripheral lung lesions. The use of the UB can be supported by navigation systems such as fluoroscopy, ultrasound guidance…
- Conditions
- Lung Cancer, Lung; Node, Lung Diseases, Lung TB
- Trial name
- NCT05526573
- Testing
- Ultrathin bronchoscopy (MP190F; Olympus Medical Systems, Tokyo, Japan)
- Where
- 3 sites in Italy
- Volunteers
- 148 people
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine
Atrial Fibrillation, Congestive Heart Failure
Comparison of Pulmonary Vein Isolation Versus AV Nodal Ablation With Biventricular Pacing for Patients With Atrial Fibrillation With Congestive Heart Failure (PABA CHF)
For patients with atrial fibrillation and heart failure, current treatment can include AV nodal ablation with biventricular pacing.
- Trial name
- PABA CHF (NCT00599976)
- Testing
- Pulmonary vein isolation
- Volunteers
- 81 people
- Sponsor
- Azienda Policlinico Umberto I
Lung Cancer Non Small Cell
A Study of Lymph Node Metastatic Pattern Based Incorporating Tumor Location, GGO Components and Size for Non-small Cell Lung Cancer
The goal of this observational study is to learn about in invasive non-small cell lung cancer patients who underwent pulmonary resection with systematic lymph node dissection from April 2008 to July 2022 .
- Trial name
- NCT06161935
- Testing
- no intervention
- Volunteers
- 7,067 people
- Sponsor
- Fudan University
Lung Cancer, Lymph Node Metastasis
Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection Specimens
Lung cancer patients undergoing upfront surgery, highly benefit from a systematic lymph node dissection in the mediastinum and in the surgical specimens. The latter is performed by the pathologist.
- Conditions
- Lung Cancer, Lymph Node Metastasis, Pathologic Processes
- Trial name
- NCT06252129
- Testing
- Subjects undergoing a lung specimen lymph node dissection, Control group
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Lung Cancer
Sentinel Lymph Node Mapping in Detecting Cancer That Has Spread to Lymph Nodes in Patients With Non-Small Cell Lung Cancer
RATIONALE: Diagnostic procedures such as sentinel lymph node mapping may improve the ability to detect cancer that has spread to the lymph nodes.
- Trial name
- NCT00089310
- Testing
- technetium-99
- Where
- 12 sites in United States
- Volunteers
- 46 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Peripheral Pulmonary Nodules, Lung; Node
CBCT-Guided Navigational Bronchoscopy For Lung Nodules
The purpose of this study is to determine if the cone beam computed tomography (CBCT)-guided navigation bronchoscopy is better in diagnosing lung nodules compared to navigation bronchoscopy alone.
- Conditions
- Peripheral Pulmonary Nodules, Lung; Node, Cone Beam Computed Tomography, Guided Navigation Bronchoscopy
- Trial name
- NCT04758403
- Testing
- Navigation Bronchoscopy, Cone beam computed tomography (CBCT)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Non Small Cell Lung Cancer, Lymph Node Metastasis
PET-CT Predicting Lymph Nodes Metastasis
This study is a single-center prospective clinical study that aims to evaluate the predictive value of preoperative 18F-FDG-PET-CT and 18F-FAPI-PET/CT for lymph node metastasis in patients with non-small cell lung cancer.
- Conditions
- Non Small Cell Lung Cancer, Lymph Node Metastasis, Positron Emission Tomography
- Trial name
- NCT05970913
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Fudan University