Clinical trials: Lung Cancer Screening Program
Lung Cancer, Blood Biomarkers
AI for Lung Cancer Risk Definition in Computed Tomography Screening Programs
Low-dose computed tomography (LDCT) lung cancer (LC) screening can reduce mortality among heavy smokers, but there is a critical need to better identify people at higher risk and to reduce harms related to management of benign…
- Trial name
- NCT06320184
- Testing
- Artificial Intelligence risk model
- Where
- Italy
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Smoking, Tobacco, Tobacco-Related Carcinoma
The Lung Screening, Tobacco and Health Project
The purpose of this study is to compare intensive telephone counseling (ITC) plus the nicotine patch vs. standard telephone counseling plus the nicotine patch (Usual Care; UC) among current smokers undergoing lung cancer…
- Conditions
- Smoking, Tobacco, Tobacco-Related Carcinoma, Tobacco Use, Lung Cancer Screening
- Trial name
- NCT03200236
- Testing
- Intensive Telephone Counseling (8 sessions) with nicotine replacement, Usual Care: Telephone counseling (3 sessions) with nicotine replacement
- Where
- 7 sites in United States
- Volunteers
- 1,114 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Cigarette Smoking, Smoking Cessation
Benefits of Tobacco Free Cigarette
Background. Smoking is considered a global public health problem. For this reason, the smoking dependence was called by experts as a global epidemic.
- Trial name
- BETOFREE (NCT02422914)
- Testing
- Smoking cessation program TFC and activity tracker, Smoking cessation program TFC-free and activity tracker, Smoking cessation program and activity tracker
- Where
- Italy
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Milan
Lung Cancer
Retrospective Epidemiological Study of Lung Cancer With Low-dose Multislice Computed Tomography
Lung cancer is one of the leading causes of cancer-related death in Taiwan. Early diagnosis of lung cancer may improve cancer survival.
- Trial name
- NCT02736643
- Volunteers
- 1,334 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Lung Carcinoma
A Tailored Screening and Smoking Cessation Program for the LGBTQ Community of Seattle
This clinical trial develops a tailored screening and smoking cessation program for the lesbian, gay, bisexual, transgender (trans) and queer (LGBTQ) community of Seattle, Washington.
- Trial name
- NCT05304390
- Testing
- Patient Navigation, Questionnaire Administration, Smoking Cessation Intervention
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Lung Cancer, Behavior
Community Support Program for Lung Cancer Screening
The research study aims to create a program for lung cancer screening attendance
- Trial name
- LCS (NCT06207435)
- Testing
- Transportation
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Lung Cancer Screening Program, Artificial Intelligence (AI)
Development of an Artificial Intelligence Model for the Identification and Prevention of Smoking-related Diseases.
The study is an interventional pilot study. The study is designed to be monocentric and it presents additional procedues.
- Trial name
- ARIA (NCT06626178)
- Testing
- Computed tomography (CT) scan low dose, Blood sampling, Tissue sampling (lung)
- Where
- Italy
- Volunteers
- 2,840 people, healthy volunteers welcome
- Sponsor
- Scientific Institute San Raffaele
Healthy
Blood Sample Collection in Subjects Participating in a Lung Cancer Screening Program
The primary objective of this study is to establish a control population to assess performance of an investigational diagnostic test targeting lung neoplasms.
- Trial name
- 2016-11 (NCT03628638)
- Testing
- Blood Sample Collection
- Where
- 31 sites in United States
- Volunteers
- 1,718 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Lung Cancer, Early Lung Cancer Detection
CHAMP Lung Cancer Screening Program
The U.S. Preventive Services Task Force recommends annual lung cancer screening (LCS) with low-dose CT for adults aged 50-80 with a ≥20 pack-year smoking history who currently smoke or quit within the past 15 years.
- Trial name
- CHAMP (NCT07572773)
- Testing
- DELFI Diagnostics FirstLook Lung Cancer Screening Blood Test, Low-Does CT Scan
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Jill Kolesar
Lung Cancer
CT Scans in Screening for Lung Cancer in Current and Former Smokers
RATIONALE: Screening tests, such as CT scanning, may help doctors find cancer cells early and plan better treatment for lung cancer.
- Trial name
- NCT00625690
- Testing
- questionnaire administration, computed tomography, evaluation of cancer risk factors
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Nebraska
Smoking Cessation
Implementation of Smoking Cessation Within NCI Community Oncology Research Program (NCORP) Sites
Evaluate a multi-faceted training program to improve short-term smoking cessation rates (<14 days post-visit) and short (3 months) and sustained abstinence (6 months) among 1,114 enrolled smokers who present for low-dose computed…
- Trial name
- OaSiS (NCT03291587)
- Testing
- Personnel Training and Coaching Calls
- Where
- 49 sites in United States
- Volunteers
- 1,094 people
- Sponsor
- Wake Forest University Health Sciences
Breast Cancer, Prostate Cancer
Eligibility Screening for the NIH Intramural Research Program Clinical Protocols
The purpose of this protocol is to provide patients with adequate informed consent to understand that screening tests with minimal health risk will be performed to evaluate their eligibility for a research study.
- Conditions
- Breast Cancer, Prostate Cancer, Lung Cancer, Sarcoma
- Trial name
- NCT00026754
- Where
- United States
- Volunteers
- 19,522 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Smoking
Program on Lung Cancer Screening and Tobacco Cessation
In this sequential, multiple assignment, randomized trial (SMART) current smokers who are eligible for lung cancer screening will be identified using the electronic medical record at the University of Minnesota and Minneapolis VA…
- Trial name
- PLUTO (NCT02597491)
- Testing
- TLC monthly, TLC quarterly, MTM
- Volunteers
- 1,000 people
- Sponsor
- University of Minnesota
Lung Cancer
Early Detection of Lung Cancer With Low-dose Multislice Computed Tomography
Lung cancer is one of the leading causes of cancer-related death in Taiwan. Early diagnosis of lung cancer may improve cancer survival.
- Trial name
- NCT02754388
- Volunteers
- 1,334 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Breast Cancer, Benign Breast Disease
Evaluating Scaleup of an Adapted Breast Cancer Early Diagnosis Program in Rwanda
Breast cancer incidence is increasing in low- and middle-income countries (LMICs) and breast cancer mortality is high in these regions largely due to late stage diagnoses.
- Conditions
- Breast Cancer, Benign Breast Disease, Cervix Cancer
- Trial name
- NCT05364138
- Where
- Rwanda
- Volunteers
- 2,357 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Lung Cancer
Lung Cancer Screening Program Using Low-dose Tomography and Metabolomic Evaluation in a Public Service.
Observational study that aims to evaluate the implementation of a lung cancer screening program in a smoker population included in a public heath service.
- Trial name
- NCT06376097
- Where
- Brazil
- Volunteers
- 1,000 people
- Sponsor
- AstraZeneca
Smoking-related Pathology, Atheroma
Structuring of a Lung Cancer Screening Program Including Clinical, Radiological and Biological Phenotyping Useful for the Development of Individualized Risk Prediction Tools: PREVALUNG ETOILE
Patients treated at the Hôpital Nord de Marseille for at least one smoking-related pathology (atheroma, chronic bronchitis, non-progressive cancer > 5 years) or with eligibility criteria for lung cancer screening (inclusion…
- Conditions
- Smoking-related Pathology, Atheroma, Chronic Bronchitis, Non-progressive Cancer > 5 Years
- Trial name
- PREVALUNG* (NCT05649046)
- Testing
- thoracic scan Low dose, BLOOD SAMPLE, FECES SAMPLE
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Heavy Smokers, Lung Cancer Screening
Akershus Cardiac Examination (ACE) 5 Study
Individuals with extensive smoking history have 2- to 3-fold increased risk of dying prematurely compared to age- and gender-matched peers.
- Conditions
- Heavy Smokers, Lung Cancer Screening, Cardiovascular Risk Profile, Cardiovascular Disease Prevention
- Trial name
- ACE5 (NCT07301489)
- Testing
- Lung Cancer Screening Plus Program, Standard of Care
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Akershus
Lung Cancer
Community Support Program for Lung Cancer Screening Volume II
This is a West Philadelphia based community project to improve adherence to lung cancer screening. The overall objective of this project is to demonstrate the impact of a community support program (CSP) on improve adherence to…
- Trial name
- LCS II (NCT06628167)
- Testing
- Transportation, Scheduling
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Lung Neoplasms, Respiratory Tract Neoplasms
Alberta Lung Cancer Screening Program
Lung cancer is the leading cause of cancer death in North America and in the world. The vast majority of lung cancers are associated with cigarette smoking.
- Trial name
- NCT02431962
- Testing
- Computed Tomography, Active smokers - Smoking cessation arm, Active smokers - Control arm
- Where
- 2 sites in Canada
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Calgary