Clinical trials: Lung Compliance
Chronic Obstructive Pulmonary Disease, Balance
Investigation of Impairments in Body Functions and Structures, Activities and Participation Restrictions in COPD
This cross-sectional study aims to investigate to the impairments in body functions and structures, activities and participation restrictions according to the International Classification of Functioning, Disability and Health…
- Conditions
- Chronic Obstructive Pulmonary Disease, Balance, Activity, Motor, Participation, Patient
- Trial name
- NCT05632120
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Acute Respiratory Failure
Neural Pressure Support for Low Pulmonary Compliance
With this interventional prospective study, we aim at comparing the effectiveness of Neural Pressure Support (NPS) in reducing respiratory work and patient-ventilator asynchronies as compared with standard Pressure Support…
- Trial name
- NPS_LowCrs (NCT05566652)
- Testing
- Neural Pressure Support, Pressure Support Ventilation
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Policlinico Hospital
Prevention and Control
PrOVE QUERI Project #1
The overall goal of this project is to test two strategies for implementing a shared decision making tool to be used by providers while talking to patients about lung cancer screening.
- Trial name
- NCT02765412
- Testing
- Webinar, Promotion, and Tool Access, LEAP, Audit and Feedback
- Where
- 8 sites in United States
- Volunteers
- 17,033 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Fibrosis, Lung Disease
Safety and Efficacy Study of Depelestat in Acute Respiratory Distress Syndrome (ARDS) Patients
The study is aimed to assess safety of Depelestat treatment, as well as efficacy on prevention and treatment of alveolar inflammation in early pulmonary fibrosis in patients suffering from persistent Acute Respiratory Distress…
- Conditions
- Fibrosis, Lung Disease, Respiratory Disorders, Respiratory Distress Syndrome, Adult
- Trial name
- NCT00455767
- Testing
- EPI-hNE4
- Where
- 14 sites in France, Italy and 2 more
- Volunteers
- 84 people
- Sponsor
- Debiopharm International SA
Asthma
Evaluation Of Patient Satisfaction Of Metered Dose Inhaler (MDI) With Counter In Asthmatics And Chronic Obstructive Pulmonary Disease Patients (COPD).
The purpose of this study is to evaluate the level of satisfaction experienced by asthma or chronic obstructive pulmonary disease (COPD) patients when using the Fluticasone/Salmeterol HFA Metered Dose Inhaler (MDI) with counter…
- Trial name
- NCT00404261
- Testing
- Fluticasone/Salmeterol HFA
- Where
- 4 sites in Australia
- Volunteers
- 132 people
- Sponsor
- GlaxoSmithKline
Covid19, Vaccine Refusal
COVID-19 Vaccine Hesitancy Among African Americans
Coronavirus disease 2019 (COVID-19) has created a "state of emergency" for African Americans in the US. Recent findings indicate 31% of adults self-reported "wait and see" of the COVID-19 vaccine, of which 16% were African…
- Conditions
- Covid19, Vaccine Refusal, Communication
- Trial name
- NCT04801030
- Testing
- YourCoViDVaxFacts
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Meharry Medical College
Asthma
Survey on the Effect of Health Related Quality of Life (QOL) Associated With Compliance of Carbocisteine in Asthma Patients
The objectives of this study are to investigate the influence on HR-QOL (SF-36 v2) resulting from the compliance of MUCODYNE Tablets or MUCODYNE DS (Dry Syrup) 50% in asthma patients whose control levels are partly controlled or…
- Trial name
- NCT01693471
- Where
- Japan
- Volunteers
- 179 people
- Sponsor
- Kyorin Pharmaceutical Co.,Ltd
COPD
ICE COPD PikoLogic® Cohort Study.Implementation, Compliance, and Effectiveness of Integrating the PikoLogic®
This is a two-step observational cohort study evaluating the impact of adding PikoLogic® to the current disease management COPD discharge protocol subsequent to an admission for COPD exacerbation.
- Trial name
- ICE (NCT02341157)
- Sponsor
- University of Louisville
Chronic Obstructive Pulmonary Disease, Compliance, Patient
AdHerencE to Treatment and quAlity of Life in COPD
The present non-interventional observational study in the Greek population aims at collecting the characteristics of COPD patients selected to be given the inhaled combination of fluticasone propionate and salmeterol in doses of…
- Conditions
- Chronic Obstructive Pulmonary Disease, Compliance, Patient, Quality of Life
- Trial name
- AHEAD (NCT03299673)
- Where
- Greece
- Volunteers
- 600 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Medication Adherence, Cystic Fibrosis
Interactive Mobile Health Information to Enhance Patient Care at a Cystic Fibrosis Center
Real-world adherence to inhaled and oral therapies for cystic fibrosis (CF) patients remains discouragingly low, ranging between 31-53% for inhaled antibiotics and 41-72% for hypertonic saline.
- Trial name
- MOMMI3CFCM (NCT03052231)
- Testing
- caremessage
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Landon Pediatric Foundation
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
RCT of Mind-body in Long COVID and Myalgic Encephalomyelitis
We are studying the effect of a mind-body treatment for people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) with or without Long COVID (LC).
- Trial name
- MILES (NCT06933173)
- Testing
- Dynamic neural retraining system
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- University of Alberta
ARDS, Human, Lung Injury, Acute
Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients
The goal of this interventional crossover study, in intubated and mechanically ventilated Acute Respiratory Distress Syndrome (ARDS) patients, is to compare two positive end-expiratory pressure (PEEP) titration techniques…
- Conditions
- ARDS, Human, Lung Injury, Acute, Respiratory Distress Syndrome, Mechanical Ventilation Complication
- Trial name
- NCT03202641
- Testing
- PEEP ARDSnet, PEEP LRM
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Massachusetts General Hospital
Medication Adherence, Asthma
AdheRence to Inhaled Corticosteroids in Asthma
It is widely recognized that asthma in adult African American patients is a significant health problem, which is partly affected by relatively low inhaled corticosteroid (ICS) adherence rates.
- Trial name
- ARICA (NCT03769519)
- Testing
- ARICA
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Duke University
Asthma
Pediatric Study to Evaluate Treatment of Persistent Moderate or Severe Asthma With the Association Fluticasone 250 mcg/Dose and Salmeterol 50 mcg/Dose - ADERE PROJECT
Prospective, parallel-group, randomized study to evaluate the compliance to the treatment of children aged between 6 and 14 years old with persistent moderate or severe asthma, receiving the association Fluticasone 250 mcg/dose…
- Trial name
- ADERE (Ped) (NCT01476059)
- Testing
- Telephone follow-up, No telephone follow-up
- Volunteers
- 472 people
- Sponsor
- GlaxoSmithKline
Glycopyrrolate
Effect of Perioperative Use of Glycopyrrolate on Lung Function in Patients Under General Anesthesia
Gastrointestinal tumor is one of the highest incidence of malignant tumors in our country, with the incidence increasing year by year.
- Trial name
- NCT05693246
- Testing
- Glycopyrrolate, normal saline
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Zhuan Zhang
Asthma
Evaluation of the Effect of Web-designed Training Developed for Asthma Patients
The study is an experimental study with pre-test-post-test control group in order to determine the effect of web-designed training developed for asthma patients on drug compliance, asthma control, and fatigue
- Trial name
- NCT04607681
- Testing
- EDUCATION
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Lung Cancer, Lung Cancer Screening
Lung Cancer Screening in Family Members and Peers of Lung Cancer Patients: a Prospective Cohort Study
Lung cancer screening of active or former heavy smokers with yearly low-dose CT allows for earlier diagnosis and better lung cancer survival.
- Conditions
- Lung Cancer, Lung Cancer Screening, Patient Empowerment
- Trial name
- NCT05645731
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nicole Ezer, MD, FRCPC, MPH
Weaning Failure
Role of Regional Lung Compliance and Dynamic Transpulmonary Driving Pressure in the Liberation Difficulty in Tracheostomized Patients Receiving Prolonged Mechanical Ventilation
This project focuses on the analysis of the correlation between transpulmonary driving pressure and uneven lung ventilation and regional lung compliance in patients using prolonged mechanical ventilation (PMV), in order to…
- Trial name
- NCT07003672
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Tuberculosis, Pulmonary
Cost-effectiveness of Two Forms of DOTS in a Demonstration Area of the DOTS Strategy in Colombia
Tuberculosis ( TB ) remains a major global public health problems and actions to ensure the diagnosis and complete treatment of all cases is the priority for the control of this disease.
- Trial name
- DOTS (NCT01945905)
- Testing
- Intramural, Extramural
- Where
- Colombia
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Fundación FES
Diarrhea., Pneumonia.
The Effectiveness of Co-packaging With Zinc to Improve Treatment of Diarrhea and Pneumonia in Guatemala
This project applies a randomized community design to test the effectiveness of health center level co-packaging and counseling messages to improve provider and caregiver behavior in the treatment of diarrhea with zinc \& oral…
- Trial name
- Zinc10 (NCT02044107)
- Testing
- Co-packaging and counseling messages
- Where
- Guatemala
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Center for Studies of Sensory Impairment, Aging and Metabolism