Clinical trials: Lung Compliance
Mechanical Power, Postoperative Pulmonary Complications (PPCs)
EIT vs Dynamic Compliance Guided PEEP Titration During Laparoscopic Gynecological Surgery
The goal of this randomized controlled clinical trial is to compare the pulmonary protective effects of two different positive end-expiratory pressure (PEEP) titrating methods in patients with non-injured lungs undergoing…
- Conditions
- Mechanical Power, Postoperative Pulmonary Complications (PPCs), Oxygenation
- Trial name
- TITRANT (NCT07170514)
- Testing
- EIT-guided PEEP titration, Cdyn-guided PEEP titration
- Where
- 3 sites in Hungary
- Volunteers
- 200 people
- Sponsor
- Pest County Flór Ferenc Hospital
COVID-19, COVID-19 Acute Respiratory Distress Syndrome
The Effect of Listening to Music During CPAP on the Agitation Levels and Compliance.
Aim: This study was conducted to determine the effect of listening to music during CPAP on the agitation levels of intensive care patients who underwent CPAP due to COVID-19 and their compliance with the treatment.
- Trial name
- NCT05102084
- Testing
- Listening to music with a bluetooth headset to patients receiving CPAP support
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- SÜMEYYE BİLGİLİ
Asthma
Comparing Asthma Action Plans for Pediatric Asthma
The purpose of this study is to evaluate and compare the relative effectiveness of two asthma action plans (pictorial versus written) in terms of asthma action plan knowledge, medication use, and family satisfaction with asthma…
- Trial name
- NCT00136305
- Testing
- Pictorial asthma action plan, Written asthma action plan
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Children's Mercy Hospital Kansas City
Severe Asthma, Asthma
Digital Self-Monitoring in Severe Asthma
This randomized controlled pilot study aimed to assess adherence to telemedicine-based home monitoring using the AioCare digital respiratory system in adults with severe asthma over a three-month period and to determine whether…
- Trial name
- NCT07393984
- Testing
- AioCare home spirometry system
- Where
- Romania
- Volunteers
- 30 people
- Sponsor
- University of Medicine and Pharmacy "Victor Babes" Timisoara
Breast Cancer, Cervical Cancer
Improving Compliance With Medical Testing Guidelines
The study hypothesis is that clearer visual presentation of guideline recommendations and educational outreach, or academic detailing, can improve guideline compliance.
- Conditions
- Breast Cancer, Cervical Cancer, Prostate Cancer, Colon Cancer
- Trial name
- NCT02430948
- Testing
- Color-coded materials, Academic detailing, Standard support
- Where
- 2 sites in United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Beth Israel Medical Center
COVID-19, Vaccine Hesitancy
Addressing COVID-19 Vaccine Hesitancy With Muliti-Level Interventions in Appalachia
The purpose of this community-engaged study is to test the ability of county-level strategies to increase uptake of COVID-19 vaccination.
- Trial name
- K-VAC (NCT06505993)
- Testing
- Health Communication, Health Communication + Structural
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Marc Kiviniemi
Acute Respiratory Distress Syndrome ARDS
Driving Pressure-guided Tidal Volume Ventilation in the Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome (ARDS) is associated with high mortality, some of which can be attributed to ventilator-induced lung injury (VILI) when artificial ventilation is not customized to the severity of lung injury.
- Trial name
- DRIVENT (NCT06322758)
- Testing
- Tidal volume customization in the acute respiratory distress syndrome
- Volunteers
- 750 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma
Symbicort Usage in Asthma Treatment and Impact of a New Therapeutic Strategy on Compliance and Asthma Control in France
Descriptive pharmacoepidemiological study on the use of Symbicort Turbuhaler in the treatment of asthma in France and impact of a new therapeutic strategy on the compliance and control of asthma
- Trial name
- SYMBIOSE (NCT00812357)
- Where
- 168 sites in France
- Volunteers
- 579 people
- Sponsor
- AstraZeneca
Cystic Fibrosis, Patient Engagement
Cystic Fibrosis Reproductive and Sexual Health Collaborative: Building Online Research Partnerships
This is a Patient-Centered Outcomes Research Institute engagement effort aimed at training researchers/providers and patients to work in research teams together online throughout the research process (including: development…
- Trial name
- NCT04999865
- Testing
- 4-part educational program to build patient-engagement methodology capacity
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Patient Participation
Role of MSCT of Chest in Differentiation Between COPD Patients According to Their Smoking Status
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality all over the world. Smoking is considered as an important risk factor, but other risk factors are present.
- Trial name
- NCT05475977
- Testing
- MSCT chest
- Volunteers
- 90 people
- Sponsor
- Somaia Ahmad AbdAllah Ahmad
Gingivitis and Periodontal Diseases, Gingivitis; Chronic
Guided Biofilm Therapy Compared to Traditional Cleaning for Treating Gingival Inflammation in Orthodontic Patients
Why is this study being done? This study is for people with braces who have gum inflammation (gingivitis), which is when gums are swollen and bleed easily.
- Conditions
- Gingivitis and Periodontal Diseases, Gingivitis; Chronic, Gingivitis, Gingival Bleeding
- Trial name
- NCT07355517
- Testing
- Guided Biofilm Therapy, Traditional Ultrasonic Scaling + Polishing
- Where
- Jordan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Vaccination Refusal, COVID-19 Pandemic
COVID-19 Messaging for Vaccination
This study will distribute videos of health professionals encouraging Covid-19 vaccination to a large sample of Facebook users, and will test the most effective ways to maximize diffusion of this vaccine-related content to…
- Trial name
- NCT05182554
- Testing
- Doctor Videos, Sharing Videos, Sharing Videos (Influencers)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Pulmonary Arterial Hypertension (PAH)
Patient-Reported Outcomes and Adherence After Transition From Inhaled Iloprost to Oral Selexipag in Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a rare and serious condition that affects the blood vessels of the lungs and can significantly limit daily activities and quality of life.
- Trial name
- PROMISE (NCT07356375)
- Testing
- Selexipag
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo General Hospital
Asthma
Mobile Phone Text for Optimizing Asthma Treatment
The study aims at providing information on how the Short Message Service (SMS) tool influences self-management in asthma patients and to assess the resulting health related effect.
- Trial name
- NCT00917410
- Testing
- SMS support
- Where
- Denmark
- Volunteers
- 244 people
- Sponsor
- University of Copenhagen
Hypertension, Substance Abuse
Linking Former Inmates to Primary Care
The Transitions Clinic Network (TCN)aims to connect former inmates to primary care using trained, culturally competent primary care providers and community health workers (CHWs).
- Conditions
- Hypertension, Substance Abuse, Asthma, Depression
- Trial name
- NCT01863290
- Testing
- Primary care redesign
- Where
- 11 sites in United States, Puerto Rico
- Volunteers
- 816 people
- Sponsor
- Yale University
Lung Compliance
Individualized Positive End-expiratory Pressure Evaluation Using the Intratidal Compliance-volume Profile in Children
The investigators assess the changes in respiratory compliance according to different levels of positive end expiratory pressure (PEEP) in children under general anesthesia.
- Trial name
- NCT03533296
- Testing
- Positive end expiratory pressure (PEEP)
- Where
- South Korea
- Volunteers
- 47 people
- Sponsor
- Seoul National University Hospital
Post-Op Infection, Adherence, Patient
The Digital Incentive Spirometer (DIS): Improving Adherence to Incentive Spirometry
The purpose of the protocol is to assess how incentive spirometer data gathered via a smartphone platform can be utilized to improve participant adherence to prescribed incentive spirometer exercises in the post-operative period.
- Conditions
- Post-Op Infection, Adherence, Patient, Pulmonary Atelectasis, Incentive Spirometry
- Trial name
- DIS (NCT03686631)
- Testing
- Smartphone Arm
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Beth Israel Deaconess Medical Center
TEST COMPLIANCE
Patient Compliance With the Spirometry Protocol
OBJECTIVE: In this study, the effect of brochure-based and video-assisted information given before spirometry on patient compliance will be evaluated. PATIENTS AND METHODS: This is a randomized controlled clinical trial.
- Trial name
- NCT05921630
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people
- Sponsor
- University of Gaziantep
Covid19, Vaccination
Trusted Messengers: Intervention to Promote COVID-19 Vaccination
The study aims to assess the impact of a multicomponent intervention to support Primary Care Provider (PCP) outreach to promote COVID-19 vaccination among vulnerable patients in and near Worcester, MA via a pragmatic, cluster…
- Trial name
- NCT04981392
- Testing
- Primary care text message outreach to unvaccinated patients and resources to support PCPs
- Where
- United States
- Volunteers
- 21,844 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Arthroscopy
Changes in Preference for Surgery of Patients Signed up for Arthroscopic Procedures
This study describes the changes in preference to arthroscopic surgery in two orthopedics departments in Denmark under the COVID-19 pandemic.
- Trial name
- NCT04370678
- Testing
- Change in preference to surgery under COVID-19 pandemic.
- Where
- Denmark
- Volunteers
- 79 people
- Sponsor
- Region Zealand