Clinical trials: Lung Disease Chronic
Chronic Obstructive Pulmonary Disease
CLEAR Model for Predicting Ventilatory Liberation in Severe COPD
This prospective observational cohort study aims to prospectively evaluate and validate the Clinical Load, Exchange, Ability of Respiration, and Reserve (CLEAR) model for predicting sustained ventilatory liberation in patients…
- Trial name
- CLEAR (NCT07579052)
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Assiut University
Bronchiectasis
Trial on The Efficacy of Hypertonic Saline on Non-CF CSLD.
To determine the efficacy of nebulized 5% hypertonic saline on cough severity and quality of life, in children with non-CF CSLD. Secondary Aims: To determine the: 1.
- Trial name
- NCT04765033
- Testing
- Nebulized 5% Hypertonic saline
- Where
- Malaysia
- Volunteers
- 46 people
- Sponsor
- University of Malaya
Heart Failure
Inspiratory Muscular Training
Objectives: To evaluate regional lung ventilation distribution in patients suffering from chronic heart failure (CHF) after completing inspiratory muscle training (IMT) and correlate it with functional capacity and quality of…
- Trial name
- NCT01593007
- Testing
- Inspiratory muscle training, Control group
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- Universidade Federal de Pernambuco
Pulmonary Disease, Chronic Obstructive
The Development, Implementation and Evaluation of Clinical Pathways for Chronic Obstructive Pulmonary Disease (COPD) in Saskatchewan
Chronic obstructive pulmonary disease (COPD) has substantial economic and human costs. To minimize these costs high quality guidelines have been developed.
- Trial name
- NCT03075709
- Testing
- Clinical Pathway (CPW)
- Where
- Canada
- Volunteers
- 800 people
- Sponsor
- University of Saskatchewan
COPD - Chronic Obstructive Pulmonary Disease, Healty Controls
Hemodynamic Responses and Brain Activity During Dual Tasks in COPD Patients Versus Healthy Individuals
Abstract Cognitive dysfunction is joint in patients with chronic obstructive pulmonary disease (COPD). In particular, there are effects in tasks that require attention, executive functions, and working memory related to the…
- Trial name
- NCT06974448
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Fatigue, Dyspnea
TaiChi-DTx for Treating Long Covid Symptoms
The randomized controlled trial will be conducted to evaluate the effectiveness of a Multi-domain Tai Chi Digital Therapy for treating the individuals suffering from the long term COVID-19 syndrome (Long COVID).
- Conditions
- Fatigue, Dyspnea, Cognitive Impairment, Muscle Pain
- Trial name
- TaiChi-DTx (NCT05419219)
- Testing
- the multi-domain Tai Chi Digital therapy Software Application
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tim Shi
Chronic Obstructive Pulmonary Disease
Bufei Jianpi Granule for Delaying Pulmonary Function Decline in Early-Stage COPD
This study aims to establish the treatment scheme of Bufei Jianpi granule for early-stage (GOLD stage 1 or 2) chronic obstructive pulmonary disease (COPD), delaying pulmonary function decline and forming high quality evidence.
- Trial name
- NCT03976700
- Testing
- Bufei Jianpi granule
- Where
- China
- Volunteers
- 612 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Postural Orthostatic Tachycardia Syndrome, COVID-19
Effects of Individual Tailored Physical Exercise in Patients With POTS After COVID-19 - a Randomized Controlled Study
Covid-19 has the potential to affect physical, cognitive and psychological functions in multiple ways. It has been clear that a significant proportion of patients with Covid-19 develop long-term symptoms.
- Conditions
- Postural Orthostatic Tachycardia Syndrome, COVID-19, Post COVID-19 Condition, Post-Acute COVID-19 Syndrome
- Trial name
- NCT05877534
- Testing
- Individual tailored exercise
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Karolinska Institutet
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
A Study to Evaluate the Integrated Dose Counter on an Albuterol Hydrofluoroalkane (HFA) Metered Dose Inhaler (MDI)
This study is evaluating the effectiveness of a dose counter for an inhaler device used to deliver medication to people diagnosed with asthma or COPD.
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Emphysema, Chronic Bronchitis
- Trial name
- NCT01302587
- Testing
- Albuterol
- Where
- 25 sites in United States
- Volunteers
- 306 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Chronic Obstructive Pulmonary Disease, Multiple Comorbidity
Program of Integrated Care for Patients With Chronic Obstructive Pulmonary Disease and Multiple Comorbidities
Many patients with chronic obstructive pulmonary disease (COPD) also have other diseases referred to as comorbidities. Often these patients require health care by a variety of health care professionals from services linked to…
- Trial name
- PICCOPD+ (NCT01648621)
- Testing
- 40 minute standardized education session, Individualized action plan, Individualized care plan
- Where
- 2 sites in Canada
- Volunteers
- 470 people
- Sponsor
- Michael Garron Hospital
COPD, Nurse's Role
Does Longitudinal Nursing Follow-up Improve Smoking Cessation in Patients Referred for COPD Screening
a monocentric study to evaluate the efficacy of a longitudinal nursing follow up in smoking cessation in patients screened for Chronic obstructive pulmonary disease (COPD).
- Trial name
- BPCO (NCT05577767)
- Where
- France
- Volunteers
- 233 people
- Sponsor
- Centre Hospitalier de Valence
COPD, Interstitial Lung Disease
MOBoxy: MoblO2 to Maintain Oxygenation
Many patients with chronic lung disease (e.g., chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD)) require supplemental oxygen (O2) at some point during their disease course.
- Trial name
- MOBoxy (NCT07222592)
- Testing
- MoblO2 control
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- National Jewish Health
Quality of Life, Exercise
The Effect of N-Acetylcystein on Quality of Life and Air Trapping During Rest and After Exercise
Treatment of COPD patients depends on the stage of the disease. First of all it is strongly recommended quit smoking, then bronchodilators drugs are added.
- Trial name
- NAC (NCT00476736)
- Testing
- Effect on small airways (N-Acetylcystein)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
Pulmonary Disease, Chronic Obstructive
Effect of Expiratory Positive Pressure on Dynamic Hyperinflation and Ability to Exercise With Upper Limbs in COPD
The study will evaluate the effect of positive airway expiratory pressure (EPAP) on patients with chronic obstructive pulmonary disease (COPD) during submaximal upper limb exercise.
- Trial name
- NCT03073564
- Testing
- Endurance test for upper limbs, Functional test
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pancreatic Exocrine Insufficiency
The Development of a Metabolomic Test to Diagnose and Quantify Pancreatic Exocrine Insufficiency (The DETECTION Study)
DETECTION. The development of a metabolomic test to diagnose and quantify pancreatic exocrine insufficiency.
- Trial name
- DETECTION (NCT05980221)
- Testing
- Metabolomics, 13C MTGT
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Pulmonary Disease, Chronic Obstructive
Study of GSK961081 in Healthy Volunteer Subjects
GSK961081 is a new long-acting bronchodilator being developed for the treatment of chronic obstructive pulmonary disease (COPD). This study is the first clinical study in humans.
- Trial name
- NCT00887406
- Testing
- GSK961081 15mcg SD, GSK961081 3mcg SD, GSK961081 50mcg SD
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
Rhinosinusitis
Laser Assisted Treatment of Chronic Sinusitis With and Without Light Activated Agents
Chronic rhinosinusitis (CRS) is common disorder which affects up to 13% of the US population. CRS affects numerous Quality of Life (QOL) factors including smell, sleep and communication.
- Trial name
- NCT00948519
- Testing
- Laser + ICG, Laser only
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- New York Head & Neck Institute
Chronic Insomnia
Cognitive Behavioral Therapy (CBT)-Insomnia for Lung Cancer
The purpose of this study is to determine whether cognitive behavioral therapy (CBT) is effective for insomnia in lung cancer survivors.
- Trial name
- NCT02121652
- Testing
- Cognitive behavioral therapy for insomnia, Healthy eating control
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- State University of New York at Buffalo
Long COVID
Cognitive Rehabilitation for Long COVID
The investigators are comparing two different methods for helping adults with Long Coronavirus (COVID) also known as Post-Coronavirus Syndrome or Post-Coronavirus Condition manage everyday cognitive challenges.
- Trial name
- STAR-C3 (NCT05676047)
- Testing
- Cognitive Rehabilitation, Education
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Chronic Graft Versus Host Disease
Tissue Immune Landscape of Graft Versus Host Disease After Allogeneic Stem Cell Transplantation (TIL-GVHD)
Graft versus Host Disease (GVHD) is frequent after allogeneic stem cell transplantation (alloSCT). GVHD occurs following 2 patterns : acute GVHD (aGVHD) or chronic GVHD (cGVHD).
- Trial name
- TIL-GVHD (NCT06247150)
- Testing
- Additional blood sample, cGVHD target tissue biopsy
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Bordeaux