Clinical trials: Lung Disease Chronic
Chronic Obstructive Pulmonary Disease
Inspiratory Muscle Training in Chronic Obstructive Pulmonary Disease
Uncertainty persists regarding the usefulness of incorporating inspiratory muscle training (IMT) in pulmonary rehabilitation programs for patients with chronic obstructive pulmonary disease.
- Trial name
- NCT01056081
- Testing
- Inspiratory muscle training
- Volunteers
- 19 people
- Sponsor
- Faculdade Evangelica do Parana
Chronic Respiratory Disease
Telemonitoring Physical Activity in Daily Life on Chronic Respiratory Patients
Physical inactivity is a consequence of chronic diseases and on Chronic Obstructive Pulmonary Disease patients is an independent predictor of the risk of hospitalizations and early mortality.
- Trial name
- SmartReab (NCT03930511)
- Testing
- Pulmonary Rehabilitation
- Where
- 2 sites in Portugal
- Volunteers
- 100 people
- Sponsor
- University of Lisbon
COPD
Effect of Physiotherapy in Hospitalized COPD Patients
Chronic obstructive pulmonary disease (COPD) impacts negatively on the balance and strength of patients. Several studies have shown that acute exacerbations (AEs) decrease, pulmonary function and survival of COPD patients, and…
- Trial name
- NCT02509299
- Testing
- Physiotherapy program 1, Physiotherapy program 2, Standard medical treatment
- Where
- Spain
- Volunteers
- 49 people
- Sponsor
- Universidad de Granada
Chronic Obstructive Pulmonary Disease
Transcutaneous Electrical Diaphragmatic Stimulation and Inspiratory Muscle Training in Patients With COPD Exacerbated
Chronic Obstructive Pulmonary Disease (COPD) is characterized by chronic airflow limitation, a qualification of impairment of respiratory muscle function, including hyperinflation and muscle weakness.
- Trial name
- NCT03844711
- Testing
- Transcutaneous electrical diaphragmatic stimulation (TEDS), Inspiratory Muscle Training (IMT), Conventional physiotherapy
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Bronchiectasis Adult, Bronchiectasis With Acute Exacerbation
Exploring How Viral Infections Affect People With Chronic Lung Disease
Many people with chronic lung disease have disease flare-ups. It was previously believed that these were mainly caused by bacteria but recent evidence suggests that viruses could be an important trigger.
- Conditions
- Bronchiectasis Adult, Bronchiectasis With Acute Exacerbation, COPD (Chronic Obstructive Pulmonary Disease), Respiratory Infection Virus
- Trial name
- PRIVILEGE (NCT06625944)
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Imperial College London
Lung; Disease, Interstitial, With Fibrosis, Pulmonary Disease, Chronic Obstructive
Deep Learning Diagnostic and Risk-stratification for IPF and COPD
Idiopathic pulmonary fibrosis (IPF), non-specific interstitial pneumonia (NSIP), and chronic obstructive pulmonary disease (COPD) are severe, progressive, irreversibly incapacitating pulmonary disorders with modest response to…
- Conditions
- Lung; Disease, Interstitial, With Fibrosis, Pulmonary Disease, Chronic Obstructive, Artificial Intelligence
- Trial name
- DeepBreath (NCT05318599)
- Testing
- Lung auscultation, Lung ultrasound, Quality of Life's questionnaires
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- Pediatric Clinical Research Platform
Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Microbiome
Prospective Cohort Study of Molecular Mechanism of Lower Respiratory Tract Microbes in Patients With AECOPD
How to reduce the rapid decline of lung function in patients with AECOPD is a clinically urgent problem to be solved. Studies have suggested that there is a bacterial flora imbalance in the lower respiratory tract of COPD…
- Trial name
- REASON (NCT04259736)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Huashan Hospital
HIV Infections, Pneumocystis Pneumonia
Pneumocystis in Pathogenesis of HIV-associated Emphysema
A. Statement of Hypotheses: HIV-infected patients have an increased incidence of emphysema compared to non-HIV-infected smokers, and it has been hypothesized that this accelerated disease progression is the result of one or more…
- Conditions
- HIV Infections, Pneumocystis Pneumonia, Emphysema, Chronic Obstructive Pulmonary Disease
- Trial name
- PACT (NCT00869544)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Pittsburgh
Bronchitis, Chronic
AVANTI - Avelox® in Acute Exacerbations of chroNic bronchiTIs
The objective of this global non-interventional study is to evaluate the impact of Acute Exacerbation of Chronic Bronchitis(AECB) on the patient and the community as well as the safety and effect of a treatment with Moxifloxacin…
- Trial name
- NCT00846911
- Testing
- Moxifloxacin (Avelox, BAY12-8039)
- Where
- 8 sites in Albania, Bosnia and Herzegovina and 6 more
- Volunteers
- 2,672 people
- Sponsor
- Bayer
Chronic Obstructive Pulmonary Diseases, Chronic Airways Limitation
Mepolizumab in Chronic Obstructive Pulmonary Diseases (COPD) With Eosinophilic Bronchitis
Some patients with chronic obstructive pulmonary diseases (COPD) have large number of specific white blood cells called eosinophils in their airways.
- Conditions
- Chronic Obstructive Pulmonary Diseases, Chronic Airways Limitation, Bronchitis
- Trial name
- NCT01463644
- Testing
- Mepolizumab
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- McMaster University
Chronic Obstructive Pulmonary Disease (COPD)
A First Time in Man Study to Asses the Safety and Tolerability of AZD7624 in Healthy Subjects
This is a First in Human study to assess the safety and tolerability of AZD7624, following inhaled administration of single ascending doses in healthy male volunteers and female volunteers of non-child bearing potential.
- Trial name
- NCT01754844
- Testing
- AZD7624
- Where
- United Kingdom
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Rehabilitation
Factors Associated With Acceptance of Home-Based Pulmonary Telerehabilitation in COPD
Pulmonary rehabilitation improves symptoms, exercise capacity, and quality of life in people with chronic obstructive pulmonary disease (COPD), but access and participation may be limited by travel, organizational, logistical…
- Trial name
- ACCEPT-TR (NCT07747571)
- Testing
- No intervention
- Where
- France
- Volunteers
- 50 people
- Sponsor
- ADIR Association
All Diagnosed Health Conditions, ADD/ADHD
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research.
- Conditions
- All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis
- Trial name
- NCT01931644
- Where
- United States
- Volunteers
- 17,667 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Chronic Obstructive Pulmonary Disease With (Acute) Exacerbation
Comparison of HFNC With NIV in Weaning COPD
High flow nasal cannula (HFNC) has been shown to improve oxygenation and facilitate weaning in hypoxemia patients. Some clinical studies show the benefits of using HFNC in COPD patients, including reducing dead space and work of…
- Trial name
- NCT03458364
- Testing
- High flow nasal cannula, Noninvasive ventilation
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Jie Li
Chronic Obstructive Pulmonary Disease
Effects of a Food Supplement on Quality of Life in Patients With Chronic Obstructive Pulmonary Disease.
It has been demonstrated that consequences of malnutrition affect a situation of risk and have negative effects on the evolution of chronic obstructive pulmonary disease (COPD), accompanied by higher morbidity and mortality.
- Trial name
- EPOCAT (NCT04815499)
- Testing
- Food supplement
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Arafarma Group, S.A.
Long COVID, Acute COVID-19
Chronic Stress as a Risk Factor for Long COVID
The disease caused by the pathogen SARS-CoV-2 is known as coronavirus disease with the acronym COVID-19. The acute phase of this condition typically lasts one to two weeks and usually results in a full recovery.
- Trial name
- StressLoC (NCT05652634)
- Where
- Austria
- Volunteers
- 380 people
- Sponsor
- Medical University of Graz
Urticaria
Efficacy Study for the Symptomatic Treatment of Chronic Idiopathic Urticaria
The objective of the study is to evaluate the efficacy and tolerability of Bilastine 20 mg Q.D., compared to Levocetirizine 5 mg Q.D. and placebo for the treatment of Chronic Idiopathic Urticaria.
- Trial name
- NCT00421109
- Testing
- Bilastine, Levocetirizine
- Where
- 50 sites in Argentina, Belgium and 5 more
- Volunteers
- 522 people
- Sponsor
- Faes Farma, S.A.
Chronic Obstructive Pulmonary Disease
Impact of Hypnosis Intervention on the Emotional Dimension of Dyspnea in Patients With COPD.
The purpose of the clinical study is to compare the effect of hypnosis intervention on the emotional dimension of the dyspnea during a pulmonary rehabilitation program to the pulmonary rehabilitation program alone.
- Trial name
- NCT04010825
- Testing
- Hypnosis intervention focused on the emotional dimension of the dyspnea
- Where
- 2 sites in France
- Volunteers
- 106 people
- Sponsor
- 5 Santé
Asthma, COPD
Asthma, Inflammation and G Protein-coupled Receptors (GPCR)
The G protein-coupled receptors (GPCRs) are a family of proteins expressed at the cell membrane. They are composed of 380 members involved in the important functions of the organism and are privileged therapeutic targets.Their…
- Trial name
- NCT00793676
- Testing
- spirometry, blood test
- Where
- 5 sites in France
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
COPD, COPD Exacerbation Acute
Relationship Between Plasma Metabolome and the Efficacy of Systemic Glucocorticoid in AECOPD
Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) significantly increases the mortality of the patients with COPD. Guidelines have recommended systemic glucocorticoid as regular treatment.
- Trial name
- NCT04710849
- Testing
- Serum metabolic markers
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
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