Clinical trials: Lung Disease Chronic
Arthritis, Rheumatoid, Inflammation
A Study To Look At The Safety Of SB-681323 In Healthy Adult Subjects After Intravenous Administration Of A Single Dose
SB-681323 inhibits the action of an enzyme which is known to contribute to the inflammation seen in such conditions as Chronic Obstructive Pulmonary Disease and Rheumatoid Arthritis.
- Trial name
- NCT00439881
- Testing
- SB-681323
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease
Intrinsic PEEP and Laryngeal Aperture in COPD
In this study the investigators aim to investigate the extent to which in patients with chronic obstructive pulmonary disease narrowing of the vocal cords causes a positive pressure within the airways thus improving airflow and…
- Trial name
- NCT02437630
- Testing
- Oesophageal balloon to measure intra-thoracic pressure, Fibre-optic laryngoscopy, standard lung function tests
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Pulmonary Disease, Chronic Obstructive, Respiratory Insufficiency
High Flow Therapy (HFT) to Treat Respiratory Insufficiency in Chronic Obstructive Pulmonary Disease (COPD)
The aim of this study is to see if the Vapotherm High Flow Therapy (HFT) device is effective to provide breathing support to patients with Chronic Obstructive Pulmonary Disease or COPD.
- Trial name
- NCT00990119
- Testing
- Vapotherm High Flow Therapy, Non-invasive positive pressure ventilation
- Where
- United States
- Sponsor
- Vapotherm, Inc.
NSCLC Stage IV, HIV
Nivolumab/Ipilimumab and Chemotherapy Combination in Advanced NSCLC Patients With HIV, HBV, HCV and Long Covid Syndrome
Study type: Phase 2 - Interventional Trial Number of patients to be enrolled: 105 Participating countries: Italy Study drugs: nivolumab and ipilimumab Cohort A: HBV and HCV patients Cohort B: HIV patients Cohort C: Long COVID…
- Conditions
- NSCLC Stage IV, HIV, HBV, HCV
- Trial name
- LUNGVIR (NCT05597800)
- Testing
- Nivolumab and Ipilimumab
- Where
- Italy
- Volunteers
- 105 people
- Sponsor
- Universita di Verona
Pulmonary Disease, Chronic Obstructive
Postmarketing Surveillance Study of Atrovent® Inhalets in Chronic Obstructive Pulmonary Disease
To obtain further information on the tolerability and efficacy of Atrovent® inhalets in the treatment of Chronic Obstructive Pulmonary Disease under conditions of daily practice
- Trial name
- NCT02238171
- Testing
- Atrovent® inhalets
- Volunteers
- 346 people
- Sponsor
- Boehringer Ingelheim
COPD
Informatics Framework for Pulmonary Rehabilitation
Previous studies clearly established clinical benefits of pulmonary rehabilitation in patients with chronic obstructive pulmonary disease however uptake and completion rate of pulmonary rehabilitation programs by these patients…
- Trial name
- CHIEF-PR (NCT03981783)
- Testing
- Best available care (BAC), Telerehabilitation (TH)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Education, Asthma
Evaluating the Collaborative Management in Pediatrics (CMP) Training Program Among Pediatric Resident Doctors and Their Patients With Asthma or Obesity
Self-care behaviors are decisions and actions that people can take to improve their health or cope with a health problem. It is important for people with long-term illnesses to develop and maintain effective self-care behaviors.
- Conditions
- Education, Asthma, Obesity
- Trial name
- CMP (NCT00510341)
- Testing
- Collaborative Management in Pediatrics (CMP) Program
- Where
- 3 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Washington
Sinusitis, Chronic
Effect of Postoperative Additive Systemic Steroids in CRSwNP
This study investigate the additive effect of systemic postoperative steroids in patients with chronic rhinosinusitis (CRSwNP). All patients receive a functional endoscopic sinus surgery (FESS) followed by topical steroid spray…
- Trial name
- NCT04915456
- Testing
- Systemic Steroid (Prednisolone)
- Volunteers
- 106 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Bronchiolitis Obliterans Syndrome, Chronic Lung Allograft Dysfunction
LAM-001 in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome.
The goal of this clinical trial is to learn about the safety and effectiveness of LAM-001 in patients who have developed bronchiolitis obliterans syndrome (BOS), a form of chronic rejection, after lung transplantation.
- Conditions
- Bronchiolitis Obliterans Syndrome, Chronic Lung Allograft Dysfunction, Lung Transplantation
- Trial name
- INSPO-BOS (NCT06018766)
- Testing
- LAM-001
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Steven Hays, MD
Disorder Related to Lung Transplantation
Copenhagen Acute Renal Complications After Transplantations Study Group
Lung transplanted patients experience marked decrease in renal function post transplant mainly due to cyclosporine induced renal changes.
- Trial name
- CARCATS (NCT02744872)
- Testing
- Felodipine
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
COPD, OSA
Efficacy of CPAP Therapy on Pulmonary Function Test in Patients With COPD-OSA Overlap Syndrome
To evaluate efficacy of CPAP Therapy on Pulmonary Function Test in Patients With COPD-OSA Overlap Syndrome
- Conditions
- COPD, OSA, Lung Function Decreased
- Trial name
- NCT05857475
- Testing
- CPAP therapy, Control
- Where
- Thailand
- Volunteers
- 10 people
- Sponsor
- Mahidol University
COPD, Pulmonary Disease
Effect of Self-directed and Supervised Pulmonary Rehabilitation Approach on Cough and Sputum.
Chronic obstructive pulmonary disease (COPD)is a multifactorial, progressive chronic lung disease that causes airflow restriction.
- Trial name
- NCT05538975
- Testing
- Physiotherapy Treatment
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Afridi Medical Complex
Noninvasive Ventilation, Chronic Disease Lung
Behavioural Intervention in Mechanically Ventilated Patients
Background: Non-invasive ventilation at home for chronic respiratory failure due to different etiologies has proven effective regarding mortality and quality of life.
- Trial name
- NCT03932175
- Testing
- Intervention group
- Where
- Spain
- Volunteers
- 67 people
- Sponsor
- Hospital Clinic of Barcelona
Lung Diseases
Glottic Width and Respiratory Flow in Patients With Various Lung Diseases
In this study the investigators examine the glottic width and the respiratory flow at rest in patients with various lung disease.
- Trial name
- NCT02460757
- Testing
- Laryngoscopy
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Hospital, Essen
COPD, Chronic Obstructive Pulmonary Disease
Leveraging Lung Cancer Screening to Optimize Screening Outcomes and COPD Management: COPD in LCS Registry
The COPD in LCS Registry will identify and characterize individuals who have functional or radiographic evidence of COPD and are receiving lung cancer screening.
- Trial name
- COPD in LCS (NCT06974981)
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Coronavirus COVID-19, Respiratory Infection
EEG as Predictor of HD-tDCS Effectiveness in Long COVID-19
COVID-19 is an infectious disease which presents a heterogenous clinical presentation. Recent investigations suggest that people who were infected by COVID-19 often develop physical disabilities (i.e.
- Trial name
- NCT05289128
- Testing
- Experimental group
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of Paraíba
Heart Failure, Congestive, Renal Failure Acute Chronic
Effect of a Focused Point-of-care Ultrasonography Screening Protocol in Hospitalized Patients
This research project aims to establish a real-time focused ultrasound examination protocol for routine assessment of hospitalized patients, including evaluations of the inferior vena cava (IVC), pericardial effusion…
- Conditions
- Heart Failure, Congestive, Renal Failure Acute Chronic, Liver Cirrhosis, Sepsis
- Trial name
- NCT07656428
- Where
- Taiwan
- Volunteers
- 9,000 people
- Sponsor
- National Taiwan University Hospital
COPD
Triple Therapy in Real-life: Impact on Adherence and Health Status (TRITRIAL)
The mean objectives are to evaluate the impact of BDP/FF/G fixed combination on health-status and adherence
- Trial name
- NCT03963167
- Testing
- BDP/FF/G fixed combination
- Where
- Italy
- Volunteers
- 661 people
- Sponsor
- Chiesi Italia
Chronic Obstructive Pulmonary Disease, Lung Disease
To Evaluate the Effect of AZD3199 on the Electrical Activity in the Heart
The purpose of this research study is to evaluate the effect of AZD3199 on the electrical activity of the heart. The effect of AZD3199 will be compared to a licensed antibiotic (moxifloxacin).
- Trial name
- NCT01222442
- Testing
- AZD3199, Moxifloxacin
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
Treatment of COPD by Autologous Transplantation of Bronchial Basal Cells
Bronchial basal cells are proved to be able to regenerate lung structures to repair the injured lung. In COPD patients, bronchus structures are injured and cannot be repaired, which may result in the failure of pulmonary function…
- Trial name
- NCT03156673
- Testing
- bronchial basal cells
- Where
- China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Shantou University Medical College
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