Clinical trials: Lung Function Testing
COVID-19
Respiratory Function 3 Months After Hospital Discharge in Critically Ill COVID-19 Patients
The objective of this single-center retrospective observational study is to describe spirometric abnormalities and their impact on 6-minute walk test (6MWT) and the physical component summary (PCS) of the SF-36 quality of life…
- Trial name
- NCT05249842
- Testing
- Spirometric evaluation, Physical component summary, 6MWT
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital Sao Domingos
Pulmonary Disease
Evaluation of the Causes and Disease Processes of Chronic Lung Disease
Chronic lung diseases are disorders associated with abnormalities in any of the structures involved in the process of breathing and bringing oxygen into the lungs and blood.
- Trial name
- NCT00001183
- Where
- United States
- Volunteers
- 6,564 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Breathing Exercises
Comparative Effects of ACBT and Diaphragmatic Breathing on Pulmonary Function and Sputum Diary After CABG
To compare the effects of active cycle of breathing technique and diaphragmatic breathing on pulmonary functions and sputum diary after coronary artery bypass graf
- Trial name
- NCT05936788
- Testing
- Active cycle of breathing technique, diaphragmatic breathing
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Pneumonia, Pneumocystis Carinii, HIV Infections
Aerosols in the Treatment of Asymptomatic Pneumocystis Pneumonia: A Pilot Study Assessing the Effectiveness of Aerosolized Pentamidine as Treatment of Subclinical Pneumocystis Infection in Patients With No Clinical Symptoms
To confirm the ability of pulmonary (lung) function testing (PFT) to detect Pneumocystis carinii pneumonia (PCP) before the development of clinical symptoms and to determine if pentamidine (PEN), a drug used in treating PCP, can…
- Trial name
- NCT00000707
- Testing
- Pentamidine isethionate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Primary Ciliary Dyskinesia
Respiratory Physiotherapy Performed by Simeox In Patients With Primary Ciliary Dyskinesia
Primary ciliary dyskinesia (PCD) is characterized by impaired airway clearance and mucus stagnation. This results in recurrent upper and lower respiratory tract infections often leading to chronic inflammation and, if not treated…
- Trial name
- NCT04793724
- Testing
- Simeox, PARI O PEP
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- University Hospital, Motol
Respiratory Disease
Contribution of Four Pulmonary Function Tests to Diagnosis in the Primary Care.
Contribution of four pulmonary function tests to diagnosis in patients with respiratory symptoms in the primary care.
- Trial name
- NCT03424083
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Obstructive Pulmonary Diseases, Restrictive Lung Disease
Database of All Patients Who Have Undergone Pulmonary Function Testing at Singapore General Hospital
The purpose of this study is to create a prospective database of all patients who have undergone pulmonary function testing from which the investigators can study the clinical phenotypes of various respiratory conditions.
- Conditions
- Obstructive Pulmonary Diseases, Restrictive Lung Disease, Cough, Dyspnea
- Trial name
- NCT01601288
- Where
- Singapore
- Volunteers
- 17,000 people
- Sponsor
- Singapore General Hospital
Lung Diseases, Interstitial
A Study to Test Different Imaging Techniques in Patients With Different Types of Interstitial Lung Disease
The main objectives of this imaging biomarker study are to assess the annual lung function change in patients with progressive fibrosing interstitial lung disease (PF-ILD) including idiopathic pulmonary fibrosis (IPF), with Usual…
- Trial name
- NCT05492994
- Testing
- Spirometry, Diffusing Capacity of the Lung for Carbon Monoxide (DLCO), Magnetic Resonance Imaging
- Where
- Germany
- Volunteers
- 31 people
- Sponsor
- Boehringer Ingelheim
Chronic Respiratory Diseases
Evaluating the Relationship Between Environmental Risk Factors in Housing Types and Chronic Respiratory Diseases in Ho Chi Minh City
The research question is "Are the different types of house in Ho Chi Minh city equally contributing to chronic respiratory diseases?".
- Trial name
- NCT02898129
- Testing
- Questionnaire, Lung function test
- Where
- Vietnam
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Brugmann University Hospital
COPD
Imposed Pursed Lip Breathing at Rest and During Exercise In COPD
A randomized control trial was conducted at physiotherapy department of Pakistan Railway General Hospital from July 2017 to Dec 2017.
- Trial name
- NCT04138069
- Testing
- PLB+Aerobic Bicycling, Aerobic Bicycling
- Where
- Pakistan
- Volunteers
- 29 people
- Sponsor
- Riphah International University
Breathing, Mouth, Lung Function Decreased
Cardiopulmonary Exercise Testing and Oscillometry for the Evaluation of Dyspnea
This study will determine if airway resistance to airflow and pressure, measured by Oscillometry, is associated with abnormal findings on Cardiopulmonary Exercise Testing in subjects who are experiencing shortness of breath.
- Conditions
- Breathing, Mouth, Lung Function Decreased, Dyspnea, Shortness of Breath
- Trial name
- COED (NCT06554353)
- Testing
- Oscillometer
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Rochester
Cystic Fibrosis
Controlled Ventilation CT in CF Infants
The objective of the study is to implement a new method of performing chest CT imaging in young children with cystic fibrosis at Packard Children's Hospital.
- Trial name
- NCT01200888
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stanford University
Chronic Low-back Pain
Respiration in Chronic Low Back Pain
The goal of this observational study is to learn about respiratory muscle strength, respiratory functions, and balance in patients with chronic low back pain.
- Trial name
- NCT05718713
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Seda Saka
Tuberculosis, Inflammation Biomarkers
Effects of Adjunct Omega-3 Long Chain Polyunsaturated Fatty Acids in Pulmonary Tuberculosis Patient: an Early Bactericidal Activity and Inflammatory Trial
The goal of this randomized controlled trial is to evaluate the early bactericidal activity, early inflammatory response, and safety of omega-3 long chain polyunsaturated fatty acid (n-3 PUFA) supplementation in adult patients…
- Conditions
- Tuberculosis, Inflammation Biomarkers, Liver Function Tests, Iron Status
- Trial name
- TREAT 3 (NCT07118059)
- Testing
- Omega-3 (EPA+DHA)
- Where
- South Africa
- Volunteers
- 40 people
- Sponsor
- North-West University, South Africa
Chronic Obstructive Pulmonary Disease
Walking Speeds in Patients With Chronic Obstructive Pulmonary Disease
A growing body of evidence suggests that in individuals with chronic lung disease their walk speed is related to their daily function and quality of life.
- Trial name
- NCT01768754
- Testing
- Usual and Fast Walking Speeds
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- West Park Healthcare Centre
Community Health Services, Respiratory Disease
INSPIRE Respiratory Health Program in Botucatu, São Paulo, Brazil
The goal of this observational study is to evaluate the implementation of the INSPIRE program and to plan actions for the preparation, coordination, monitoring, diagnosis, and treatment of respiratory diseases in the municipality…
- Conditions
- Community Health Services, Respiratory Disease, Tobacco Smoking
- Trial name
- NCT06673225
- Testing
- Analysis of results
- Where
- Brazil
- Volunteers
- 2,000 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Respiratory Muscles, Respiration, Artificial
Visualization of Inspiratory Effort and Respiratory Mechanics to Promote Lung- and Diaphragm Protective Ventilation
This is a multicentre prospective cohort trial in adult and pediatric ICU patients. The investigators will measure the effect of a patient's inspiratory effort during mechanical ventilation on the lungs and diaphragm.
- Conditions
- Respiratory Muscles, Respiration, Artificial, Respiratory Function Tests
- Trial name
- VIREM (NCT05459116)
- Testing
- Placement of nasogastric balloon
- Where
- 3 sites in Belgium, Canada
- Volunteers
- 150 people
- Sponsor
- University Hospital, Antwerp
Asthma
6-Minute Pegboard and Ring Test Unsupported Arm Function Exercise Test in Asthma Patients
Exercise intolerance is one of the most problems in chronic obstructive pulmonary disease (COPD) and occurs not only in performing lower body tasks but also in performing arm activities.
- Trial name
- NCT03693664
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Hacettepe University
Hemodynamic Instability, Surgery
End-expiratory Occlusion Test and Lung Recruitment Maneuver to Assess Fluid responsiVeness In Surgical Patients
The functional hemodynamic test (FHT) called passive leg raising (PLR) has been successfully used for assessing the fluid responsiveness in ICU patients since 2009 and its reliability has been confirmed by three large…
- Conditions
- Hemodynamic Instability, Surgery, Fluid Overload
- Trial name
- ELVIS (NCT03820440)
- Testing
- End-expiratory occlusion test (EEOT), Lung recruitment manovre (LRM)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Humanitas Clinical and Research Center
Cardiopulmonary Exercise Test, End-Tidal Carbon Dioxide
Test-Retest Reliability And Validation For End-Tidal Carbon Dioxide Measurement (PetCO2) During Rest And Low-Loaded Steady State Work Using A Portable Capnograph.
The goal of this observational study is to investigate exhaled carbon dioxide measuring during rest and low-loaded work using a portable device (capnograph) and standard of care apparatus during a cardiopulmonary exercise test…
- Conditions
- Cardiopulmonary Exercise Test, End-Tidal Carbon Dioxide, VO2max, Ventilatory Physiology
- Trial name
- NCT07326449
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Linkoeping University