Clinical trials: Lupus Flare
Systemic Lupus Erythematosus
Biomarkers of Lupus Disease: Serial Biomarker Sampling in Patients With Active Systemic Lupus Erythematosus (SLE)
Hypothesis: A reason for repeated disappointing outcomes of clinical trials testing targeted immune biologics for lupus may be the heterogeneity of the disease, exacerbated by the variable effects on immune homeostasis of the…
- Trial name
- BOLD (NCT00987831)
- Testing
- Group B SLE one blood donation, Blood drawing only Group C, Group A SLE prospective study
- Where
- 2 sites in United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Oklahoma Medical Research Foundation
System; Lupus Erythematosus, Lupus Erythematosus
Translation of a Diagnostic Test for Lupus Flare Prediction From Bench to Clinic
This study is investigating the development of a diagnostic test intended to predict flares in patients with Systemic Lupus Erythematosus.
- Conditions
- System; Lupus Erythematosus, Lupus Erythematosus, SLE, Lupus Flare
- Trial name
- TOTAL FEEDBACK (NCT04018222)
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Progentec Diagnostics, Inc.
Lupus Erythematosus
Prognosis Assessment of the Increase of GADD34 Gene Expression for Patient Suffering From Systemic Lupus Erythematosus
Given that GADD34 has been described as a potential key regulator of pro-inflammatory cytokine production in human and elevated blood marker in SLE patients, this study aim to prove that the GADD34 RNA level in mononuclear blood…
- Trial name
- GADD34-LES (NCT02455089)
- Testing
- GADD34 RNA level measurement.
- Where
- 7 sites in France
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Systemic Lupus Erthematosus, Lupus Glomerulonephritis
Renal Resistive Index as an Indicator of Lupus Nephritis Severity and Systemic Lupus Activity
The study explores the role of the colour Doppler scanning of the renal arteries and its relation to the degree of disease affection in lupus nephritis
- Conditions
- Systemic Lupus Erthematosus, Lupus Glomerulonephritis, Lupus Flare
- Trial name
- NCT06757725
- Testing
- colour doppler of the renal artery and measurement of resistive index
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital