Clinical trials: Luteal Phase Defect
Menstruation Disturbances, Luteal Phase Defect
Energy Restriction and Hormones in Premenopausal Women
A growing body of epidemiological and biological evidence strongly suggests that physical activity may reduce the risk of breast cancer.
- Trial name
- NCT05107804
- Testing
- Exercise+CR, Light Conditioning
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Penn State University
Luteal Phase Defect
Progesterone in Luteal Phase Deficiency
The main objective of this study will be to assess the efficacy of natural progesterone at a daily dose of 25 mg in restoring a normal luteal phase. The primary end-point will be the ongoing pregnancy rate.
- Trial name
- NCT02950948
- Testing
- Progesterone
- Sponsor
- IBSA Institut Biochimique SA
Implantation; Placenta, Pregnancy Loss
Luteal Support in Frozen-Thawed Embryo Transfer Cycles
This study evaluates the clinical efficacy of 3 different luteal phase support in patients undergoing frozen-thawed embryo transfer cycles. Endometrium preparation will be hormone replacement in all cycles.
- Conditions
- Implantation; Placenta, Pregnancy Loss, Frozen Embryo, Luteal Support
- Trial name
- NCT03948022
- Testing
- Dydrogesterone 10Mg Tablet (duphaston), Progesterone 50Mg/mL Oil, Crinone 8% Vaginal Gel
- Where
- Turkey (Türkiye)
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Centrum Clinic IVF Center
IVF, Embryo Loss
Luteal Support in Artificial Vitrified/Warmed Cycles With Low Progesterone
The study aims to evaluate the effect of an increased dose of vaginal progesterone supplementation on the incidence of ongoing pregnancy for patients with a suboptimal serum progesterone level (defined as < 10 mcg/l) on the day…
- Conditions
- IVF, Embryo Loss, Luteal Phase Defect
- Trial name
- PROTECTA (NCT04806919)
- Testing
- Progesteron TID
- Where
- 2 sites in Belgium
- Volunteers
- 87 people
- Sponsor
- University Hospital, Ghent
Menstruation Disturbances, Luteal Phase Defect
Bioenergetics of Exercise-Induced Menstrual Disturbances
Menstrual disturbances are frequently observed in physically active women and female athletes. Short term prospective studies have shown that diet and exercise interventions can lead to decreases in Luteinizing hormone (LH)…
- Conditions
- Menstruation Disturbances, Luteal Phase Defect, Amenorrhea, Oligomenorrhea
- Trial name
- BioE (NCT04938622)
- Testing
- Sedentary Control, Exercising control, 15 percent energy deficit
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Penn State University
Luteal Phase Defect
Progesterone Levels and Clinical Outcomes Using a Single Pessary of 400 mg of Vaginal Progesterone in Substitutive Cycles for Embryo Transfer.
This study aims to compare the efficacy, in terms of progesterone levels and clinical outcomes, of two different presentations of micronized vaginal progesterone (400 mg vs.
- Trial name
- CycloCT (NCT04722471)
- Testing
- Vaginally administered progesterone
- Where
- Spain
- Volunteers
- 347 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Luteal Phase Defect
Dydrogesterone Versus Intravaginal Progesterone in the Luteal Phase Support
The purpose of this study is to compare efficacy and tolerability of the dydrogesterone and the vaginal progesterone, used for luteal phase support.
- Trial name
- NCT01178931
- Testing
- Oral dydrogesterone, Crinone 8% gel
- Where
- Croatia
- Volunteers
- 853 people
- Sponsor
- University of Zagreb
Pregnancy Related, Fertility Issues
Luteal Phase Support in IUI MOH Treatment Luteal Phase Support in IUI MOH Treatment
The LUMO study is a multicenter, randomized controlled trial that evaluates the effectivity of luteal phase support in MOH/IUI treatment.
- Conditions
- Pregnancy Related, Fertility Issues, Luteal Phase Defect, Infertility Unexplained
- Trial name
- LUMO (NCT05080569)
- Testing
- Progesterone Vaginal Product
- Where
- Netherlands
- Volunteers
- 1,008 people
- Sponsor
- UMC Utrecht
Luteal Phase Deficiency, Luteal Phase Support
An Open Labeled RCT on the Effect of Additional hCG Injection for LPS on Pregnancy Outcomes in IHH Patients
Luteal phase deficiency (LPD) accounts for most failures of assistant artificial reproduction (ART) and early pregnancy loss for patients with idiopathic hypogonadotropic hypogonadism (IHH).
- Conditions
- Luteal Phase Deficiency, Luteal Phase Support, Idiopathic Hypogonadotropic Hypogonadism
- Trial name
- LPS-IHH (NCT05569577)
- Testing
- Additional hCG injection, estrogen and dydrogesterone
- Where
- 2 sites in China
- Volunteers
- 46 people
- Sponsor
- Fudan University
Luteal Phase Defect
Effects of Varied Estrogen Doses on Endometrial Receptivity
This study will help determine the effect of varied estradiol levels on the uterine lining in healthy humans that are not undergoing a stimulated in vitro fertilization (IVF) cycle.
- Trial name
- NCT02458404
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
IVF, Luteal Phase Defect
Luteal Phase Support In IVF Women Using GnRH Agonist
Lately, the role of GnRH agonist as luteal phase support has been recommended by various studies though the mechanism is still debatable.
- Trial name
- NCT04174378
- Testing
- Decapeptyl 0.2mg
- Where
- Malaysia
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia