Clinical trials: Luteal Support
Infertility
Vaginal Progesterone Versus Progesterone in Oil in Donor Egg Recipient In Vitro Fertilization Cycles Utilizing Vitrified Donor Eggs
The aim of this study is to evaluate both pharmaceutical therapy and advanced treatment techniques for infertile patients requiring in-vitro fertilization utilizing donor eggs.
- Trial name
- NCT01465373
- Testing
- Endometrin, Progesterone in Oil
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fertility Centers of Illinois
Infertility
GnRH Agonist Trigger and Modified Luteal Phase Support, Adding a Bolus of GnRHa at the Time of Implantation - a RCT
Purpose:The aim of this project is to prospectively determine whether a single dose of GnRH-agonist administered at the time of implantation increases or not the reproductive outcome in patients undergoing in vitro fertilization…
- Trial name
- GTMLPSGI (NCT02053779)
- Testing
- Triptorelin 0.1mg
- Where
- Algeria
- Volunteers
- 328 people
- Sponsor
- Centre Hospitalier Universitaire Ibn Rochd
Controlled Ovarian Stimulation
Endometrial Luteal Phase Characteristics and Luteal Phase Support in Controlled Ovarian Stimulation Protocols With GnRH Antagonists:Focusing on MicroRNA
MiRNAs are single-stranded small non-coding RNAs that act on specific mRNAs to regulate the gene expression. Studies have suggested that miRNAs influence cellular activities in the uterus, including cell differentiation and…
- Trial name
- NCT01510054
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
ICSI
Luteal Phase Support With Estradiol In Poor Responders Undergoing In Vitro Fertilization
The role of progesterone (P) supplementation in the luteal phase of in vitro fertilization (IVF) cycles is well established world-wide , but the influence of the luteal phase estradiol level on implantation is not clearly defined…
- Trial name
- NCT03788681
- Testing
- Estradiol Valerate
- Where
- Egypt
- Volunteers
- 170 people
- Sponsor
- Ain Shams University
Implantation; Placenta, Pregnancy Loss
Luteal Support in Frozen-Thawed Embryo Transfer Cycles
This study evaluates the clinical efficacy of 3 different luteal phase support in patients undergoing frozen-thawed embryo transfer cycles. Endometrium preparation will be hormone replacement in all cycles.
- Conditions
- Implantation; Placenta, Pregnancy Loss, Frozen Embryo, Luteal Support
- Trial name
- NCT03948022
- Testing
- Dydrogesterone 10Mg Tablet (duphaston), Progesterone 50Mg/mL Oil, Crinone 8% Vaginal Gel
- Where
- Turkey (Türkiye)
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Centrum Clinic IVF Center
Infertility
Luteal Phase Support With Daily Administration of Gonadotropin-releasing Hormone Agonist Compared to Progesterone/Estradiol in IVF/ICSI Cycles With Ovulation Triggering With GnRH-a
Purpose: To determine the efficacy and safety of daily injections of gonadotropin-releasing hormone agonist in comparison with the standard strategy of supporting the luteal phase in protocols with gonadotropin-releasing hormone…
- Trial name
- NCT05143723
- Testing
- Gonadotropin-releasing hormone agonist
- Where
- Russia
- Volunteers
- 102 people
- Sponsor
- Kuban State Medical University
Infertility
Luteal Phase Progesterone in IUI and Gonadotropin Cycles
This is a study of patients undergoing Controlled Ovarian Hyperstimulation (COH) with Gonadotropins and Intrauterine Insemination (IUI) at a Fertility Clinic.
- Trial name
- NCT01941875
- Testing
- Progesterone Effervescent Vaginal Tablets
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Infertility
GNRH Agonist Trigger and Modified Luteal Phase Adding a Bolus of GnRHa at the Time of Implantation: a RCT
Purpose:The aim of this project is to prospectively determine whether a single dose of GnRH-agonist administered at the time of implantation increases or not the reproductive outcome in patients undergoing in vitro fertilization…
- Trial name
- NCT03039049
- Testing
- Triptorelin 0.1 mg
- Where
- 2 sites in Algeria
- Volunteers
- 328 people
- Sponsor
- Centre Hospitalier Universitaire Ibn Rochd
Infertility
Progesterone Versus Progesterone Plus Dydrogesterone in FET
Frozen embryo transfer (FET) has been increasing important in IVF. Progesterone is essential for the endometrial secretory transformation, establishment and maintenance of pregnancy.
- Trial name
- MiDRONE (NCT03998761)
- Testing
- Micronized Progesterone, Micronized progesterone plus dydrogesterone
- Where
- Vietnam
- Volunteers
- 1,364 people
- Sponsor
- Mỹ Đức Hospital
GnRH Agonist
Effect of GnRH Agonist in FET
To evaluate the impact of single dose GnRH agonist administration as luteal phase support on pregnancy outcomes in frozen ICSI cycle
- Trial name
- gnrh agonist (NCT07653282)
- Testing
- GnRH agonist
- Where
- Egypt
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Assiut University
IVF
Lactobacillus for Luteal Phase Support
The aim of this study was to evaluate the effect of vaginal lactobacilli, a regulator of normal vaginal flora, on embryo implantation success during IVF / ICSI cycle follow-up.
- Trial name
- NCT04044599
- Testing
- Gynoflor
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Uludag University
Infertility
Timing of Initiation of Luteal Phase Support in Poor Responders Undergoing IVF/ICSI
It is already known that all stimulated IVF ICSI cycles needs luteal phase support for higher pregnancy rates The current study will focus on evaluating two different starting times of luteal phase support
- Trial name
- NCT03938064
- Testing
- Prontogest 400 mg vaginal pessaries
- Where
- 2 sites in Egypt
- Volunteers
- 520 people
- Sponsor
- Ain Shams Maternity Hospital
Pregnancy Rate
The Effect of GnRH Administration During Luteal Support in Frozen-thawed Transfer Cycles
GnRH administration during the luteal phase was found to significantly increase pregnancy rates in women undergoing fresh-cycle IVF cycles.
- Trial name
- NCT01933009
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Infertility
The Value of Addition of Human Menopausal Gonadotropin Drug Following Oocytes Retrieval in IVF Cycles
The aim of this study is to test the hypothesis that addition of daily small dose of human menopausal gonadotropin (HMG) drug following oocytes retrieval could improve the fertility outcome in women undergoing in-vitro…
- Trial name
- NCT03209687
- Testing
- human menopausal gonadotropin
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Cairo University
ART
Oral Dydrogesterone vs. Vaginal Micronized Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer
The current trial is intended to assess the efficacy of oral versus vaginal progesterone for luteal support in frozen IVF cycles.
- Trial name
- NCT03832699
- Testing
- Dydrogesterone 10 MG, Endometrin 100Mg Vaginal Insert
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Infertility, Pregnancy
Sexual Absorption of Vaginal Progesterone
The purpose of this study is to determine if sexual intercourse lowers serum progesterone in women using vaginal progesterone gel (Crinone®), and increases serum progesterone in their male sexual partners.
- Trial name
- NCT01959464
- Testing
- Crinone vaginal progesterone gel
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
GnRH Antagonist IVF Protocol, Fresh Embryo Transfer
GnRH for Luteal Support - Mechanism of Action
This prospective observational study will include women undergoing IVF treatment with a GnRH antagonist protocol and fresh embryo transfer at the IVF unit of Shaare Zedek Medical Center.
- Conditions
- GnRH Antagonist IVF Protocol, Fresh Embryo Transfer, Administration of Hormonal Luteal Support
- Trial name
- NCT07620067
- Testing
- GnRH agonist, Progesterone
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Heli Alexandroni
Infertility
GnRH for Luteal Support in IVF/ICSI/FET Cycles
During IVF cycles an embryo is generally placed into the uterine cavity between 3 and 5 days after fertilization. For a successful pregnancy to take place, that embryo must then implant in the properly primed and staged…
- Trial name
- NCT02357654
- Testing
- GnRH
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University Reproductive Associates
Infertility, In Vitro Fertilization
Patients' Preference for Subcutaneous or Vaginal Progesterone as Luteal Support in IVF/ICSI Cycles
This randomized, controlled, prospective, crossover, open-label, two-treatments, two-period trial aimed to evaluate the preference expressed by the patient concerning the subcutaneous administration of progesterone versus the…
- Trial name
- NCT03181685
- Testing
- Progesterone 25 MG subcutaneous, Micronized progesterone 200 MG, recombinant FSH
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Andros Day Surgery Clinic
Progesterone
Comparison of the Effect of Subcutaneous Progesterone and Vaginal Progesterone for Luteal Phase Support
The invesigators aimed to seperate the patients,which is going to be applied IUI, to two different groups as prospective randomized controlled ;assess the efficacy of the two different way pressurised progesterone by appling…
- Trial name
- NCT05276531
- Testing
- subcutaneous progesterone, vaginal progesterone
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University