Clinical trials: Lutein
Retinitis Pigmentosa
Clinical Trial of Lutein for Patients With Retinitis Pigmentosa Receiving Vitamin A
The purpose of this trial is to determine whether lutein in addition to vitamin A will slow the course of retinitis pigmentosa.
- Trial name
- NCT00346333
- Testing
- Lutein, Cornstarch control
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- National Eye Institute (NEI)
Lactation
Dietary Lutein and the Retinopathy of Prematurity
The clinical trial aspect of this study is the provision of a lutein supplement to lactating women and compare the amount of lutein in the milk and blood with lactating women who do not receive the lutein supplement.
- Trial name
- NCT00672230
- Testing
- Lutein supplement
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Osteogenesis
Clinical and Radiographic Assessment of PRF Versus Lutein Placement
Thirty patients seeking for prosthetic replacement of non-restorable single rooted maxillary teeth by dental implant placement will be selected from the Out-Patient Clinic of Oral and Maxillofacial Surgery Department, Faculty of…
- Trial name
- NCT06358352
- Testing
- Lutein / Zeaxanthin, Platelet rich fibrin
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Retinal Detachment
Randomized Controlled Trial of LUtein as a Novel Neuroprotective Adjunctive Therapy to Improve Visual Outcome of Rhegmatogenous Retinal Detachment (LUNAR Study)
Retinal detachment is a major cause of blindness, particularly among contemporary Asian populations due to the high prevalence of myopia. Without timely treatment, retinal detachment invariably results in blindness.
- Trial name
- NCT03932305
- Testing
- Lutein
- Volunteers
- 110 people
- Sponsor
- Singapore National Eye Centre
Aging, Wrinkle
Evaluation of the Benefits of FloraGLO™ Lutein on Skin Health
Therefore, the present study is designed to contribute to the body of literature by investigating the effect of 12-weeks of lutein supplementation on multiple parameters of skin health and appearance in healthy women.
- Conditions
- Aging, Wrinkle, Skin Elasticity, Healthy
- Trial name
- NCT03769779
- Testing
- FloraGLO Lutein, Safflower Oil
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kemin Foods LC
Raman Spectroscopy
Raman Scattering Spectroscopy to Measure Macular Pigment
This study will evaluate the ease and reliability of Raman scattering spectroscopy, a new technique to measure the amount of the pigment lutein in the retina, the light-sensitive tissue lining the back of the eye.
- Trial name
- NCT00060580
- Testing
- Raman scattering spectroscopy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Age-related Macular Degeneration, Cataract
Age-Related Eye Disease Study 2 (AREDS2)
Oral supplementation with the Age-Related Eye Disease Study (AREDS) formulation (antioxidant vitamins C and E, beta carotene, and zinc) has been shown to reduce the risk of progression to advanced age-related macular degeneration…
- Trial name
- AREDS2 (NCT00345176)
- Testing
- Lutein/zeaxanthin, DHA/EPA, Lutein/zeaxanthin and DHA/EPA
- Where
- 91 sites in United States
- Volunteers
- 4,203 people
- Sponsor
- National Eye Institute (NEI)
Macula Lutea Opacity
Food or Supplemental Lutein Absorption
The aim of this study is to investigate in healthy adults, 18-40 years of age, how the absorption of 5 mg of L differs between consumption as a supplement, blended foods, and whole food equivalent of blended foods.
- Trial name
- FSLA20 (NCT04786392)
- Testing
- Lutein supplement, Food, blended, Food, unprocessed
- Where
- Australia
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Queensland
Inflammation, Skin Abnormalities
Effects of Bend Beauty's Anti-Aging Formula on Inflammatory Markers
This is a phase IV, randomized, double-blind, placebo-controlled, three-arm, parallel intervention study including three groups of 25 subjects between 35-65 years of age, treated with either Bend Beauty's Anti-Aging Formula, fish…
- Conditions
- Inflammation, Skin Abnormalities, Skin Pigment, Inflammatory Response
- Trial name
- BENCHMARK (NCT03862872)
- Testing
- Anti-Aging Formula, Control Fish Oil
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bend Beauty Inc.
Mild Cognitive Impairment
The Effects of a Carotenoid Intervention on Cognitive Function
Past research suggests that retinal lutein levels are related to cognitive function as measured via behavioral tests. The goal of the present study is to investigate the relationship between lutein and cognitive function in a…
- Trial name
- NCT02023645
- Testing
- active supplement
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Age-Related Macular Degeneration
Effects of Lutein Supplementation on Macular Pigment Optical Density and Visual Acuity in Patients With Age-related Macular Degeneration
The macular pigment (MP) in humans consists of the yellow, blue-absorbing carotenoids lutein and zeaxanthin. The highest concentrations of lutein and zeaxanthin are found in the fovea.
- Trial name
- NCT00879671
- Testing
- lutamax (leutein)
- Where
- Austria
- Volunteers
- 126 people
- Sponsor
- Medical University of Vienna
Coronary Artery Disease, Diabetes
Benefits of Eggs in Combination With a Plant-based Diet
The main objective of the study is to demonstrate that the inclusion of eggs to a plant-based diet will not increase the risk for heart disease but will increase the concentration of lutein and zeaxanthin, two important…
- Conditions
- Coronary Artery Disease, Diabetes, Metabolic Syndrome
- Trial name
- NCT04234334
- Testing
- Consume 2 eggs with spinach per day, Egg Subsitute with spinach per day
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Antioxidant Role of the Lutein in Preterm Newborn
Early Administration of the Lutein/Zeaxanthin in Premature Newborns
Premature birth is the most common cause of mortality, morbidity and disability. Premature infants have a higher risk of developing damage in the eyes (retinopathy of prematurity ROP), in the central nervous system…
- Trial name
- NCT03340103
- Testing
- LUTEIN ofta 0,5 gocce
- Where
- 4 sites in Italy
- Sponsor
- Sooft Italia
Changes in Macular Pigment Optical Density
Regional Kale as Source of Lutein and Zeaxanthin to Improve Vision of AMD-patients
The age-related macular degeneration (AMD) is an age-dependent, multi-factorial disease. In Western industrial countries, it is the main cause of visual impairments. In Germany, approximately 4.5 million people suffer from AMD.
- Trial name
- KALESIGHT (NCT02136303)
- Testing
- S1: Dosage-dependency, S2: Kale extract versus kale purée, S3: Kale extract: AMD-patients
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Jena
Age Related Maculopathy
Long Term Effects of Lutein/Zeaxanthin and Omega-3- Supplementation on Optical Density of AMD Patients (LUTEGA)
The primary objective of LUTEGA is it to determine the long term effect (about 1 year) of the supplementation with a fixed combination of lutein/zeaxanthin and omega-3- fatty acids on the optical density (OD) of macular pigment…
- Trial name
- LUTEGA (NCT00763659)
- Testing
- Lutein/ Zeaxanthin + Omega-3-FA
- Where
- Germany
- Volunteers
- 172 people
- Sponsor
- University of Jena
Age Macular Degeneration
Study of the Macular Pigment by the Consumption of Corn With Strong Content in Zeaxanthine
The Age Macular Degeneration (AMD) is the first cause of blindness in industrialized countries. The macular pigment (lutein and zeaxanthin) could play an important role in the arisen of the AMD.
- Trial name
- MAIS (NCT02113254)
- Testing
- Corn zeaxanthin
- Where
- France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Infant, Newborn, Diseases, Other Lipid Storage Disorders
Evaluation of Antioxidant Activity of Oral Lutein in Preterm and Term Newborn
The balance of the redox state is important for normal embryonic and fetal development . During the perinatal period, a variety of conditions are responsible for an excessive production of free radicals.
- Trial name
- NCT02068807
- Testing
- Lutein drops, Glucose drops
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Siena
Menopausal Syndrome, Cognitive Decline
Algal Lutein Against Decline of Intellectual Nimbleness
Lutein is a xanthophyll pigment found in photosynthesizing organisms. Its beneficial effects on health, including brain function and visual performance, have been recognized for many years.
- Conditions
- Menopausal Syndrome, Cognitive Decline, Obesity & Overweight, Menopause
- Trial name
- ALADIN (NCT07600567)
- Testing
- Lutein
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Breastfeeding, Exclusive
Synergistic Activity of Human Milk Nutrients and Infant Cognition
Purpose: To establish a whole food, egg, as a viable study material to supplement mothers and infants with nutrients that support optimal brain development. There will be 84 breastfeeding dyads, 3 months postnatal.
- Trial name
- NCT03838536
- Testing
- Whole Egg Powder, Egg White Powder
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Vasomotor Symptoms
Goji Berry and Vasomotor Symptoms Pilot Study
The goal of this clinical trial is to compare two forms of goji berry powder-whole goji berry powder and goji juice powder-in peri- and postmenopausal women aged 40-65 years who experience frequent vasomotor symptoms (hot…
- Trial name
- GOJI-VMS (NCT07660315)
- Testing
- Goji Berry Juice Powder, Goji Berry Powder
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of California, Davis