Clinical trials: Lymph Node
Bladder Cancer
Robotic-Assisted Laparoscopic Extended Pelvic Lymph Node Dissection for Transitional Cell Carcinoma of the Bladder
The goal of this clinical research study is to evaluate how many lymph nodes are left behind after robotic-assisted removal and are then found after a wider incision is made, in patients who are having their bladder removed for…
- Trial name
- NCT00963859
- Testing
- Robotic-assisted laparoscopic surgery
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- M.D. Anderson Cancer Center
Pediatric Patients With Solid Tumors
A Study Comparing Green Fluorescent Dye and Radioactive Dye for Sentinel Lymph Node Biopsy in Pediatric Cancers
This study is being done in patients that have tumors to find out how well sentinel lymph nodes (SLNs) can be found with a special dye called indocyanine green (ICG).
- Trial name
- NCT02910726
- Testing
- Sentinel Lymph Node Biopsy, indocyanine green (ICG)
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Endometrial Cancer, Uterine Cancer
A Study Assessing the Safety and Utility of PINPOINT® Near Infrared Fluorescence Imaging in the Identification of Lymph Nodes in Patients With Uterine and Cervical Malignancies Who Are Undergoing Lymph Node Mapping
This is a randomized, prospective, open label, multicenter study to assess the safety and utility of PINPOINT® Near Infrared Fluorescence Imaging (PINPOINT) in identification of lymph nodes (LN) in patients with uterine and…
- Conditions
- Endometrial Cancer, Uterine Cancer, Cervical Cancer
- Trial name
- FILM (NCT02209532)
- Testing
- PINPOINT
- Where
- 8 sites in United States, Canada and 1 more
- Volunteers
- 180 people
- Sponsor
- Novadaq Technologies ULC, now a part of Stryker
Non Small Cell Lung Cancer
Zactima in Non Small Cell Lung Cancer (NSCLC) ELderly Patients In Combination With or Versus Gemcitabine
The primary objective of this study is to demonstrate an improvement in Progression-Free Survival (PFS) for the combination of vandetanib plus gemcitabine compared with gemcitabine plus placebo in chemonaïve (not including an…
- Trial name
- ZELIG (NCT00753714)
- Testing
- ZD6474, Vandetanib, Gemcitabine
- Where
- 15 sites in Italy
- Volunteers
- 124 people
- Sponsor
- Genzyme, a Sanofi Company
Breast Cancer
Surgical Breast Resection With or Without Axillary Lymph Node Excision in Treating Women With Breast Cancer
This randomized phase III trial is studying surgery and axillary lymph node dissection to evaluate if systematic Axillary Lymph Node Excision can be avoided in locoregional treatment for operable breast cancer smaller than 10 mm…
- Trial name
- AXIL95 (NCT00210236)
- Testing
- Conventional surgery WITHOUT Axillary Lymph Node Excision, Conventional surgery WITH Axillary Lymph Node Excision
- Where
- 14 sites in France
- Volunteers
- 625 people
- Sponsor
- Institut Bergonié
Cervical Cancer
A Phase II Study of Extended Field IMRT External Beam Irradiation and Intracavitary Brachytherapy
Recent studies have shown that the chance of survival among women with advanced cervical cancer is increased when they receive concurrent chemotherapy and radiation to the pelvis.
- Trial name
- NCT00590967
- Testing
- IMRT extended field external beam radiation therapy, Brachytherapy, Cisplatin
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Washington University School of Medicine
Diffuse Large B-cell Lymphoma
Phase III Study of RAD001 Adjuvant Therapy in Poor Risk Patients With Diffuse Large B-Cell Lymphoma (DLBCL) of RAD001 Versus Matching Placebo After Patients Have Achieved Complete Response With First-line Rituximab-chemotherapy
Phase III study of RAD001 adjuvant therapy in poor risk patients with Diffuse Large B-Cell Lymphoma (DLBCL) of RAD001 versus matching placebo after patients had achieved complete response with first-line rituximab-chemotherapy
- Trial name
- PILLAR2 (NCT00790036)
- Testing
- Everolimus
- Where
- 202 sites in United States, Argentina and 32 more
- Volunteers
- 742 people
- Sponsor
- Novartis Pharmaceuticals
Mucocutaneous Lymph Node Syndrome
KIDCARE (Kawasaki Disease Comparative Effectiveness Trial)
Kawasaki disease (KD) is a self-limited illness that affects the heart blood vessels (coronary arteries) of infants and children and is now the most common cause of acquired heart disease in children.
- Trial name
- KIDCARE (NCT03065244)
- Testing
- IVIG, Infliximab
- Where
- 29 sites in United States
- Volunteers
- 105 people
- Sponsor
- University of California, San Diego
Prostate Cancer
Intensity Modulated Radiation Therapy (IMRT) Radiotherapy for Treating Prostate Pelvic Nodes
The purpose of this study is to examine the clinical feasibility and efficacy of uing IMRT to escalate the biologically effective dose to the pelvic lymph nodes in a short course of radiation therapy.
- Trial name
- NCT00214136
- Testing
- radiotherapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Wisconsin, Madison
Uterine Cervical Neoplasms
A Trial of Comparing the Pathology Status of Lymphoseek®-Identified Sentinel Lymph Nodes Relative to the Pathological Pathology Status of Nonsentinel Lymph Nodes in Nodal Staging of Subjects With Known Cancer of the Cervix Who Are Undergoing Lymph Node Dissection
Prospective, open-label, within-patient, multi-center study of Lymphoseek in the detection of lymph nodes in subjects with known cancer of the cervix.
- Trial name
- NCT02509585
- Testing
- Tc99m tilmanocept
- Where
- 4 sites in United States
- Volunteers
- 18 people
- Sponsor
- Cardinal Health 414, LLC
Stage I Breast Cancer, Stage II Breast Cancer
Comparison of Use of Indocyanine Green and 99mTc-labeled Radiotracer for Axillary Lymphatic Mapping in Patients With Breast Cancer
This clinical trial will enroll up to 130 adult women with a confirmed diagnosis of clinical stage 1 or 2 breast cancer who are undergoing breast cancer surgery with lumpectomy or mastectomy and planned axillary sentinel node…
- Trial name
- NCT02419807
- Testing
- Indocyanine Green Solution, Technetium Tc-99m Sulfur Colloid, Lymphoscintigraphy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Case Comprehensive Cancer Center
Lung Cancer, Complication of Surgical Procedure
Comparison of LigaSure to Conventional Electrocoagulation in Video-assisted Thoracoscopic Surgery Lobectomy
Surgical treatment of lung cancer consists of two elements: anatomical lung resection (segmentectomy, lobectomy or pneumonectomy) followed by mediastinal lymph node dissection (MLND).
- Trial name
- NCT03125798
- Testing
- LigaSure™, Monopolar electrocautery
- Where
- Poland
- Volunteers
- 216 people
- Sponsor
- Wielkopolskie Centrum Pulmonologii i Torakochirurgii
Breast Cancer, Cancer of the Breast
Real-time Intraoperative Breast Cancer Visualization for Margin Assessment
The investigators' preclinical data have demonstrated the feasibility of fluorescence-guided tumor resection by Cancer Vision Goggles (CVG) with LS301 in animal models.
- Trial name
- NCT02807597
- Testing
- LS301, Cancer Vision Goggles and standard fluorescence imaging systems, Surgery
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Samuel Achilefu
Lymph Node, Breastcancer
CK19 Combined With Contrast-enhanced Ultrasound: a Prediction System on Axillary Lymph Node Metastasis in Breast Cancer
To establish a predicting system on axillary lymph node metastasis based on peripheral blood CK19mRNA and contrast-enhanced ultrasound.
- Trial name
- CK-CEUS (NCT02992067)
- Where
- China
- Volunteers
- 359 people
- Sponsor
- Zhejiang Cancer Hospital
Healthy Subject
Effect of Pneumatic Tourniquet on Arm Swelling After Lymph Node Removal
The purpose of the proposed study is to evaluate the acute impact of swelling caused by low-pressure tourniquet use in the setting of ipsilateral prior axillary lymph node dissection and the change in swelling reduction following…
- Trial name
- NCT03584100
- Testing
- Tourniquet 8000
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Stanford University
Kawasaki Disease
Pharmacokinetics (PK)/Safety Study of Atorvastatin in Children With Kawasaki Disease and Coronary Artery Abnormalities
Kawasaki disease (KD) is the leading cause of acquired heart disease in children in the developed world. Despite available treatment, 25% of children in San Diego County appropriately treated for KD develop coronary artery…
- Trial name
- NCT01431105
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of California, San Diego
Breast Adenocarcinoma
Doxorubicin Hydrochloride, Cyclophosphamide, and Paclitaxel With or Without Bevacizumab in Treating Patients With Lymph Node-Positive or High-Risk, Lymph Node-Negative Breast Cancer
This randomized phase III trial studies doxorubicin hydrochloride, cyclophosphamide, and paclitaxel to see how well they work with or without bevacizumab in treating patients with cancer that has spread to the lymph nodes (lymph…
- Trial name
- NCT00433511
- Testing
- Bevacizumab, Cyclophosphamide, Doxorubicin Hydrochloride
- Where
- 842 sites in United States, Peru and 1 more
- Volunteers
- 4,994 people
- Sponsor
- National Cancer Institute (NCI)
Sentinel Lymph Node Biopsy, Breast Cancer
A Study to Find the Best Dose of ASP5354 to Show Lymph Nodes in People With Breast Cancer or Melanoma During Surgery
This study was for women with breast cancer and for adults with melanoma. Breast cancer was a type of cancer when cells in the breast turn into cancer cells, which might grow out of control.
- Conditions
- Sentinel Lymph Node Biopsy, Breast Cancer, Melanoma
- Trial name
- NCT05457842
- Testing
- pudexacianinium chloride
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Astellas Pharma Inc
Head and Neck Squamous Cell Carcinoma (HNSCC)
Evaluation of Sentinel Lymph Nodes in Head and Neck Squamous Cell Carcinoma
The purpose of this study is to determine the false negative rate (FNR) associated with Lymphoseek-identified sentinel lymph nodes (SLNs) relative to the pathological status of non-sentinel lymph nodes in elective neck dissection…
- Trial name
- NCT00911326
- Testing
- Lymphoseek
- Where
- 13 sites in United States
- Volunteers
- 101 people
- Sponsor
- Navidea Biopharmaceuticals
Kawasaki Disease, Coronary Aneurysm
Doxycycline Treatment to Prevent Progressive Coronary Artery Dilation in Children With Kawasaki Disease
Kawasaki disease (KD) affects infants and young children causing inflammation of the skin and blood vessels including the coronary arteries of the heart.
- Trial name
- NCT01917721
- Testing
- Doxycycline
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Hawaii Pacific Health