Clinical trials: Lymph Node
Breast Cancer
Spot tm Tattooing of Biopsied Axillary Lymph Nodes With Ultrasound Guided in Breast Cancer Patients Prior to Surgery
To assess feasibility and clinical utility of marking biopsied axillary lymph nodes with Spot at time of biopsy.
- Trial name
- NCT02617264
- Testing
- SPOT
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Kaplan Medical Center
Head and Neck Carcinoma, Head and Neck Lymph Node
Photoacoustic Imaging for Measuring Tumors and Normal Tissue in Patients With Head and Neck Cancer
This trial studies how well photoacoustic imaging works in measuring tumors and normal tissue in patients with head and neck cancer.
- Conditions
- Head and Neck Carcinoma, Head and Neck Lymph Node, Head and Neck Squamous Cell Carcinoma, Laryngeal Neoplasm
- Trial name
- NCT04110249
- Testing
- Photoacoustic Imaging, Transcutaneous Acupoint Electrical Stimulation
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Roswell Park Cancer Institute
Vulval Cancer, Sentinel Lymph Node Detection
Charcoal Carbon Black Dye Use in Sentinel Lymph Node Mapping in Early Stage Vulvar Cancer
The aim of this study is to investigate the detection rate, sensitivity and specifity of charcoal carbon black dye as a sentinel lymph node tracer in inguinofemoral lymph node(s) in early stage vulvar cancer
- Trial name
- IFLND (NCT06694116)
- Testing
- sentinel lymph node biopsy using carbon dye
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Colorectal Neoplasms, Neoplasm Metastasis
Clinical Trial Comparing Carnoy's and GEWF Solutions for Lymph Node Clearing Technique in Colorectal Cancer
Regional lymph node metastasis is a major determinant of local recurrence and overall survival rates in patients with colorectal cancer.
- Trial name
- NCT02495532
- Testing
- Lymph node clearing technique with Carnoy solution, Lymph node clearing technique with GEWF solution
- Where
- Brazil
- Volunteers
- 126 people
- Sponsor
- Hospital Moinhos de Vento
Breast Cancer, Breast Neoplasms
PET-MRI for Axillary Staging in Node Negative Breast Cancer Patients
Axillary lymph node status is an important prognostic factor for patients with breast cancer. After breast cancer diagnosis, current nodal staging consists of axillary ultrasound (US) combined with tissue sampling when deemed…
- Conditions
- Breast Cancer, Breast Neoplasms, Breast Diseases
- Trial name
- NCT03374826
- Testing
- Dedicated axillary hybrid PET-MRI
- Where
- 2 sites in Netherlands
- Volunteers
- 125 people
- Sponsor
- Maastricht University Medical Center
Endometrial Cancer
Pelvic Sentinel Node Detection Using Indocyanine Green Learning Curve
According to ESGO-ESTRO-ESMO guidelines, pelvic Sentinel lymph node detection is suitable for lymph node staging in endometrial carcinoma of the uteri.
- Trial name
- ENDO-GREEN (NCT04958278)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Secondary Malignant Neoplasm of Lymph Node, Prostatic Neoplasms
Lymph Node Involvement Using Extended Pelvic Lymphadenectomy in Clinically Localized Prostate Cancer
Prostate cancer is considered the fourth most common malignancy cancer in America. However, in Colombia the incidence is higher, and it is considered the second cause of death among men for malignance diseases.
- Trial name
- LNIEPLCLPC (NCT02156414)
- Testing
- Radical Prostatectomy, Extended Lymphadenectomy
- Where
- 3 sites in Colombia
- Volunteers
- 135 people
- Sponsor
- Javeriana University
Thyroid Cancer
Selective Neck Dissection Versus Modified Neck Dissection in PTC
This study is a phase III, randomized controlled, open label non inferiority study. Patients who meet the inclusion criteria are randomly assigned 1:1 to either the experimental group (selective neck dissection) or the control…
- Trial name
- NCT06554652
- Testing
- Lymph node tracer navigated selective neck dissection, Modified neck dissection
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Fudan University
Breast Carcinoma Metastatic in Lymph Node, Stage II Breast Cancer AJCC v6 and v7
Magseed Magnetic Marker in Locating Axillary Lymph Nodes in Patients With Breast Cancer Undergoing Surgery
This phase IV trial studies the side effects of the Magseed magnetic marker and how well it works in locating lymph nodes in the underarm area in patients with breast cancer undergoing surgery.
- Conditions
- Breast Carcinoma Metastatic in Lymph Node, Stage II Breast Cancer AJCC v6 and v7, Stage IIA Breast Cancer AJCC v6 and v7, Stage IIB Breast Cancer AJCC v6 and v7
- Trial name
- NCT03038152
- Testing
- Axillary Lymph Node Dissection, Localization, Medical Device
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- M.D. Anderson Cancer Center
Melanoma, Surgery
Perioperative Examination of Inflammatory Markers in Relation to Sentinel Lymph Node Biopsy in Patients With Melanoma; a Pilot Study
We want to test if an association between sentinel lymph node biopsy (SLBN) and a systemic inflammatory response can be made.
- Trial name
- NCT05817149
- Testing
- Blood samples
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Aalborg University Hospital
Breast Cancer
Breast Lymph Node Mapping
The purpose of this study is to map the arm lymphatic drainage system in the axilla with blue dye and the breast drainage system with a radioactive material.
- Trial name
- NCT01038908
- Testing
- Isosulfan Blue (Patent Blue Dye V)
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Breast Cancer
Internal Mammary Sentinel Lymph Node Biopsy With Modified Injection Technique
Internal Mammary Lymph Node (IMLN) and Axillary Lymph Node (ALN) are regarded as "the first station" of lymphatic drainage in breast cancer, serving as an important reference for lymph staging and decision-making.
- Trial name
- NCT03541278
- Testing
- MIT, IM-SLNB
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Shandong Cancer Hospital and Institute
Lymph Nodes With Tumor Metastasis
Predicting Tumor Origin Based on Deep Learning of Lymph Node Puncture Cytology
In this study, the investigators aimed to construct a deep learning diagnostic model that uses cytological images to predict primary unknown tumor origins in patients with tumors combined with lymph node metastases.
- Trial name
- NCT06810349
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Pancreatic Adenocarcinoma, Lymph Node Metastasis
EUS Role in Non-metastatic Pancreatic Adenocarcinoma Lymph Nodes Staging
Aim of the study will be to investigate if Endoscopic Ultrasound (EUS) with elastography can be purposed between the routine staging examinations in patients with pancreatic adenocarcinoma without distant metastasis for the…
- Trial name
- NCT06341725
- Testing
- malignant lymph nodes
- Where
- Italy
- Volunteers
- 2 people
- Sponsor
- Paolo Giorgio Arcidiacono, MD
Breast Cancer, Cognitive/Functional Effects
Doxorubicin and Cyclophosphamide in Treating Older Women With Stage I, Stage II, or Stage III Breast Cancer That Has Been Removed By Surgery
RATIONALE: Drugs used in chemotherapy, such as doxorubicin and cyclophosphamide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Breast Cancer, Cognitive/Functional Effects, Depression, Malnutrition
- Trial name
- NCT00424203
- Testing
- AC regimen, cyclophosphamide, doxorubicin hydrochloride
- Where
- 17 sites in France
- Volunteers
- 40 people
- Sponsor
- UNICANCER
Cancer, Malignant Melanoma
Effect of rIL-21 on Metastases in Lymph Nodes in Melanoma Skin Cancer
The trial is conducted in Europe. This trial aims for a comparison of the pathology in lymph nodes before and after the effect of recombinant interleukin-21 in patients with stage III melanoma
- Trial name
- NCT00601861
- Testing
- recombinant interleukin-21
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- Novo Nordisk A/S
Melanoma
NIR-Guided Sentinel Lymph Node Mapping in Melanoma
This study will try to define an appropriate dose of the investigational drug indocyanine green (ICG) in combination with near infrared (NIR) imaging to use for future studies.
- Trial name
- NCT01121718
- Testing
- ICG Intervention
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer
Sequential Administration of FE75C and Docetaxel Versus Docetaxel/Cyclophosphamide in HER-2 Negative, Node Positive Breast Cancer
In this trial investigators propose to assess the dose dense, G-CSF supported sequential administration of 4 cycles of FEC followed by 4 cycles of docetaxel versus 6 cycles of docetaxel/cyclophosphamide as adjuvant chemotherapy…
- Trial name
- NCT01985724
- Testing
- Docetaxel, Epirubicin, Cyclophosphamide
- Where
- 10 sites in Greece
- Volunteers
- 650 people
- Sponsor
- Hellenic Oncology Research Group
Lung Cancer
EBUS/Spectrum Analysis
To evaluate the clinical benefit of spectrum analysis of endobronchial ultrasound images of lymph nodes during EBUS TBNA for lymph node staging in patients with lung cancer.
- Trial name
- NCT01972386
- Testing
- Spectrum Image Analysis using a Linear Array Ultrasound Bronchoscope
- Where
- Canada
- Volunteers
- 122 people
- Sponsor
- University Health Network, Toronto
Neoplasm Metastasis, Secondary Malignant Neoplasm of Lymph Node
Negative Pressure Wound Therapy in Groin Dissection
This study investigates the use of a negative pressure wound therapy device (PICO™, Smith \& Nephew Healthcare, UK) on clean, closed surgical wounds, in patients who are undergoing inguinal lymphadenectomy for metastatic…
- Conditions
- Neoplasm Metastasis, Secondary Malignant Neoplasm of Lymph Node, Non-healing Surgical Wound (Disorder), Skin Neoplasms
- Trial name
- NCT02408835
- Testing
- PICO™
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- South Eastern Health and Social Care Trust
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