Clinical trials: Lymph Node
Sentinel Lymph Node Biopsy, Neoadjuvant Therapy
Clinical Application of Multi-modal Sentinel Lymph Node Staining Method in Breast Cancer Patients After Neoadjuvant Chemotherapy
This clinical trial aimed to confirm the effectiveness of sentinel lymph node surgery by determining the lymph node identification rate using multimodal sentinel lymph node marker methods in patients with advanced breast cancer…
- Conditions
- Sentinel Lymph Node Biopsy, Neoadjuvant Therapy, Breast Neoplasm
- Trial name
- NCT06212440
- Testing
- Radioactive Isotope (RI) Mapping, Indocyanine Green Fluorescence (ICG-F) Mapping, Vital Dye Mapping
- Where
- 2 sites in South Korea
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Colorectal Cancer
Magnetic Particle-ICG Lymph Node Mapping in Colorectal Cancer
Study to determine the feasibility of Sentinel Lymph Node (SLN) mapping using novel magnetic tracers (FerroTrace) and indocyanine green (ICG) for colorectal cancer; and to evaluate safety by assessing short term toxicity…
- Trial name
- NCT05092750
- Testing
- FerroTraceTM, indocyanine green (ICG)
- Sponsor
- M.D. Anderson Cancer Center
Colon Cancer, Colon Surgery
Indocyanine Green (ICG) in the ex Vivo Detection of Sentinel Lymph Node (SLN)in Colon Cancer
Evaluation of the possibility to detect sentinel lymph node(s) after ex vivo Indocyanine Green injections around the tumour in pieces of colectomy from patients with colon cancer.
- Trial name
- 2068 (NCT01995591)
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Jules Bordet Institute
Breast Cancer
Molecular Marker Profiling of Axillary Lymph Nodes in Predicting Response in Patients With Locally Advanced or Metastatic Breast Cancer Who Are Undergoing Chemotherapy Followed By Surgery
RATIONALE: Comparing results of diagnostic procedures, such as molecular marker profiling, done before and after chemotherapy, may help doctors predict a patient's response to treatment and help plan the best treatment.
- Trial name
- NCT00233974
- Testing
- PET (positron emission tomography)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cervical Cancer
Laparoscopic Sentinel Lymph Node Localization in Operable Cervix Cancer
The purpose of this study is to evaluate the feasibility, safety and efficacy of laparoscopic ovarian transposition in women less than 40 years of age with locally advanced cervical squamous cell carcinoma
- Trial name
- NCT00205010
- Testing
- Lymphoscintigraphy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Breast Neoplasms
Axillary Ultrasound With or Without Sentinel Lymph Node Biopsy in Detecting the Spread of Breast Cancer in Patients Receiving Breast Conservation Therapy
This randomized clinical trial studies two different tests that are currently being used to detect the spread of breast cancer to the lymph nodes under the arm in candidates for breast conservation therapy.
- Trial name
- NCT01821768
- Testing
- Sentinel Lymph Node Biopsy
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Washington University School of Medicine
Prostate Cancer
Tumor-directed Radiation Therapy for Patients With the Highest Risk Category of Localized Prostate Cancer
HYPO-RT-PC boost is is an open-label, multicentre, phase II trial evaluating safety and efficacy of real-time image-guided tumor-directed ultra-hypofractionated radiation boost and lymph node irradiation for patients with…
- Trial name
- NCT06220435
- Testing
- Ultra-hypofractionated radiotherapy regimen.
- Where
- 2 sites in Sweden
- Volunteers
- 76 people
- Sponsor
- Region Skane
Testicular Cancer
Voiding and Erectile Function After Retroperitoneal Lymph Node Dissection for Testicular Cancer
This study aims to evaluate how retroperitoneal lymph node dissection (RPLND), a surgical treatment for testicular cancer, may affect urinary and sexual functions in men.
- Trial name
- VEEF-RPLND-TC (NCT06954233)
- Testing
- Uroflowmetry and questionnaires
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- Jagiellonian University
Melanoma (Skin)
Interferon Alfa Following Surgery in Treating Patients With Stage III Melanoma
RATIONALE: Interferon alfa may interfere with the growth of the cancer cells. It is not yet known if this treatment is more effective than observation following surgery for stage III melanoma.
- Trial name
- NCT00006249
- Testing
- pegylated interferon alfa, adjuvant therapy
- Where
- 104 sites in Australia, Belgium and 16 more
- Volunteers
- 1,258 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Breast Cancer
Magnetic Resonance Imaging Using Ferumoxtran-10 in Finding Metastases to the Axillary Lymph Nodes in Patients With Breast Cancer
RATIONALE: Diagnostic procedures, such as magnetic resonance imaging (MRI) using ferumoxtran-10, may help find and diagnose breast cancer that may have spread to the axillary lymph nodes and may help in planning breast cancer…
- Trial name
- NCT00107484
- Testing
- ferumoxtran-10, magnetic resonance imaging, sentinel lymph node biopsy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Virginia Commonwealth University
Recurrence
Lymph Node Ratio as a Predictor for Outcome in Rectal Cancer
This study aims to evaluate the value of the LNR as a prognostic indicator in patients with rectal cancer who offered total mesorectal excision.
- Trial name
- NCT05221684
- Testing
- Lymph node harvesting
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Mansoura University
Splenic Hilum Lymph Nodes Dissection
3D Versus 2D Laparoscopic Total Gastrectomy With Splenic Hilum Lymph Nodes Dissection
The investigators will perform a prospective randomized comparison between 3D and 2D laparoscopic total gastrectomy with splenic hilum lymph nodes dissection.
- Trial name
- NCT02984787
- Testing
- 3D Laparoscopic total gastrectomy, 2D Laparoscopic total gastrectomy
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Chinese PLA General Hospital
Cutaneous Melanoma
Intradermal Injection of Anti-CTLA-4 in Patients With Stage I/II Melanoma
This study evaluates the clinical safety and tolerability, and the immunological effects of local intradermal injection of tremelimumab in patients with clinical stage I/II melanoma patients undergoing a sentinel node biopsy…
- Trial name
- NCT04274816
- Testing
- Tremelimumab
- Volunteers
- 13 people
- Sponsor
- A.J.M. van den Eertwegh
Cancer, Shoulder Pain
Effectiveness of Oncological Physiotherapy on Painful Shoulder Cervical Ganglion in Head and Neck Cancer
Objective: To estimate whether oncological physiotherapy treatment with neurodynamic and kinesitherapy (passive and active) in patients with "painful shoulder due to accessory spinal nerve dissection" operated on for head and…
- Conditions
- Cancer, Shoulder Pain, Rehabilitation
- Trial name
- NCT05604235
- Testing
- Therapeutic upper limb strength exercise treatment, Treatment with passive and active mobilization of the upper limb.
- Where
- 3 sites in Spain
- Volunteers
- 20 people
- Sponsor
- University of Alcala
Wilms Tumor
Treatment of Newly Diagnosed Patient's With Wilm's Tumor Requiring Abdominal Radiation Delivered With Proton Beam Irradiation
Participants are being asked to take part in this clinical trial, a type of research study, because the participants have a Wilms Tumor cancer.
- Trial name
- NCT04968990
- Testing
- Proton Beam Radiation (PBRT), DD-4A Chemotherapy Regimen, Complete Surgical Resection
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- St. Jude Children's Research Hospital
Lymph Node Metastases
Central Cervical Dissection for Clinical Node Negative Papillary Thyroid Carcinoma
This study is divided into three stages. In the first stage, the investigators try to explore the objective clinical imaging standard of cN0PTC on the basis of previous studies, formulate the "clinical imaging standard of…
- Trial name
- NCT03813173
- Testing
- lymph node dissection
- Volunteers
- 6,000 people
- Sponsor
- Zhejiang University
Porocarcinoma, Sentinel Lymph Node
Sentinel Lymph Node Biopsy in Porocarcinoma
Eccrine porocarcinoma (EPC) is a slow-growing carcinoma arising from the eccrine sweat glands. Based on its clinical presentation it can be confused with malignant and benign skin lesions, both.
- Trial name
- NCT03647631
- Testing
- sentinel lymph node biopsy
- Where
- Italy
- Volunteers
- 2 people
- Sponsor
- Ospedale Policlinico San Martino
Metastatic Melanoma to the Groin Lymph Nodes
Evaluation of Groin Lymphadenectomy Extent For Metastatic Melanoma
BACKGROUND: Spread of metastatic melanoma to the groin lymph nodes (LN) is a common event affecting about 350 people a year in Australia.
- Trial name
- EAGLE FM (NCT02166788)
- Testing
- Inguinal Lymphadenectomy, Ilio-inguinal Lymphadenectomy
- Where
- 17 sites in Australia, Brazil and 4 more
- Volunteers
- 634 people
- Sponsor
- Melanoma and Skin Cancer Trials Limited
Postoperative Analgesia, Pain, Postoperative
Superficial Serratus Plane Block for Modified Radical Mastectomy and Axillary Lymph Node Disection
Breast cancer is the most common type of cancer in women. Mastectomy and axillary lymph node disection are commonly performed as part of the cancer management. This surgery can cause significant postoperative pain.
- Conditions
- Postoperative Analgesia, Pain, Postoperative, Opioid Consumption
- Trial name
- NCT03341234
- Testing
- Bupivacaine, Saline, Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ataturk University
Breast Cancer
Chemotherapy Omission in HR-positive/HER2-negative Breast Cancer With Lymph Node Negative Disease Receiving Adjuvant Endocrine Therapy and CDK4/6 Inhibitor
This is a prospective, randomized, open-label, multicenter phase III study to explore chemotherapy omission in hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer with lymph node…
- Trial name
- NCT06996093
- Testing
- 4 cycles of TC (docetaxel + cyclophosphamide) adjuvant chemotherapy, aromatase inhibitor (± ovarian suppression) plus CDK4/6 inhibitor
- Where
- China
- Volunteers
- 2,508 people
- Sponsor
- Fudan University
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