Clinical trials: Lymph Node
Invasive Breast Cancer
Computed Tomography (CT) Reconstruction for Axillary Lymph Node Structure
This is a prospective, single-center, non-randomized, non-controlled observational study.
- Trial name
- CTREP (NCT03247478)
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Peking University
Kawasaki Disease
Multi-center Prospective Randomized Control Trail of High Dose Aspirin in Acute Stage of Kawasaki Disease
Kawasaki disease (KD) is an acute multi-system vasculitis syndrome of unknown etiology occurring mostly in infants and children younger than 5 years of age.
- Trial name
- NCT02359643
- Testing
- Aspirin
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Breast Cancer
Clinical Application of Dual Sentinel Lymph Node Staining Method in Breast Cancer Patients
This study aimed to compare detection rate between dual sentinel node staining method using mixture of indocyanine green (ICG) with radioisotope(RI), and RI only.
- Trial name
- NCT02479997
- Testing
- Indocyanine green, Radioisotope
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- National Cancer Center, Korea
Breast Cancer
Selective Image Guided Resection of Pathologically Documented Axillary Lymph Node Metastases
The purpose of this research study is to determine how feasible and accurate identifying and removing specific lymph nodes in the axilla (armpit) after neoadjuvant systemic therapy is when patients present with breast cancer that…
- Trial name
- TAD (NCT03281720)
- Testing
- TAD
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Head and Neck Cancer
Lymph Node Assessment Using Simultaneous 18F-FDG-PET and MRI
The overarching goal of this study is to develop PET/MR techniques to accurately detect nodal metastases for surgical planning and assessment of treatment response.
- Trial name
- NCT02180308
- Testing
- PET/MRI
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- NYU Langone Health
Papillary Thyroid Carcinoma
Multimodal Deep Learning for Lymph Node Metastasis in Thyroid Cancer
Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy in clinical practice, accounting for approximately 85% of all thyroid malignancies.
- Trial name
- NCT07299318
- Testing
- not intervention
- Where
- China
- Volunteers
- 3,200 people
- Sponsor
- West China Hospital
Thyroid Cancer Patients, Lymph Node Metastasis
Irreversible Electroporation for Recurrent or Metastatic Cervical Lymph Node Metastases From Thyroid Cancer: A Prospective Multicenter Single-Arm Study
This is a single-arm, open-label, multicenter, exploratory clinical trial designed to systematically evaluate the efficacy, safety, and patient benefit of ultrasound-guided irreversible electroporation (IRE) ablation for…
- Trial name
- IRE-TCLN (NCT07328243)
- Testing
- Irreversible Electroporation (IRE) Ablation
- Where
- 3 sites in China
- Volunteers
- 85 people
- Sponsor
- Tian'an Jiang
Head and Neck Squamous Cell Carcinoma (HNSCC)
Evaluation of Sentinel Lymph Nodes in Head and Neck Squamous Cell Carcinoma
The purpose of this study is to determine the false negative rate (FNR) associated with Lymphoseek-identified sentinel lymph nodes (SLNs) relative to the pathological status of non-sentinel lymph nodes in elective neck dissection…
- Trial name
- NCT00911326
- Testing
- Lymphoseek
- Where
- 13 sites in United States
- Volunteers
- 101 people
- Sponsor
- Navidea Biopharmaceuticals
Esophageal Neoplasms
Adjuvant Therapies or Surgery Alone for High Risk pN0 Esophageal Cancer
Histological Node Negative thoracic esophageal squamous cell carcinoma（pN0 ESCC） after radical resection still carries the risk of recurrence after complete surgical resection, especially in some high-risk patients.
- Trial name
- NCT02891083
- Testing
- Adjuvant chemotherapy (Paclitaxel and Cisplatin), Adjuvant radiotherapy, Control group (Surgery alone)
- Where
- China
- Volunteers
- 486 people
- Sponsor
- Shanghai Chest Hospital
Stage I Endometrial Carcinoma, Stage II Endometrial Carcinoma
Lymph Node Mapping in Patients With Newly Diagnosed Endometrial Cancer Undergoing Surgery
This clinical trial studies lymph node mapping in patients with newly diagnosed endometrial cancer undergoing surgery. Lymph node mapping may help in planning surgery to remove endometrial cancer and affected lymph nodes.
- Conditions
- Stage I Endometrial Carcinoma, Stage II Endometrial Carcinoma, Stage III Endometrial Carcinoma, Stage IV Endometrial Carcinoma
- Trial name
- NCT01939028
- Testing
- lymph node mapping, sentinel lymph node biopsy, isosulfan blue
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Case Comprehensive Cancer Center
Melanoma
RP1 in Primary Melanoma to Reduce the Risk of Sentinel Lymph Node Metastasis
This early-phase study will examine Vusolimogene Oderparepvec, a genetically modified oncolytic viral strain of the herpes simplex type 1 (HSV-1) virus, with potential oncolytic, immunostimulating and antineoplastic activities.
- Trial name
- NCT06216938
- Testing
- Vusolimogene oderparepvec (RP1)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Yana Najjar
Breast Carcinoma
Quality of Life, Employment, and Informal Care Costs in Women Who Are Receiving Chemotherapy for Breast Cancer
This research trial studies quality of life, employment, and informal care cost analysis in patients with breast cancer receiving chemotherapy.
- Trial name
- NCT00115505
- Testing
- quality-of-life assessment, Questionnaire Administration
- Where
- 227 sites in United States
- Volunteers
- 307 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Breast Cancer
Sentinel lympH Node Biopsy With Indocyanine Green in Breast Cancer After NEoadjuvant Chemotherapy (SHINE)
This is a prospective, open-label, within-patient clinical trial to determine the accuracy of Indocyanine green (ICG) guided sentinel lymph node biopsy (SLNB) compared to the standard dual-tracer SLNB in breast cancer patients…
- Trial name
- SHINE (NCT06085274)
- Testing
- ICG guided sentinel lymph node biopsy
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Lung Cancer, Lymph Nodes
Transbronchial Needle Forceps for Endobronchial Ultrasound
Prove the feasibility of a needle forceps in patients with enlarged mediastinal lymph nodes
- Trial name
- NCT01145924
- Testing
- EBUS TBNF
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Heidelberg University
Head and Neck Squamous Cell Cancer
Induction Chemo Then Concurrent Chemoradiotherapy With Cetuximab in Locally Advanced Head and Neck Squamous Cell Cancer
This is an open label, single arm Phase II study of induction chemotherapy followed by concurrent chemo-radiotherapy in patients with locally advanced head and neck squamous cell cancer (HNSCC) using monoclonal antibody…
- Trial name
- NCT01326923
- Testing
- Cetuximab
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Colonic Neoplasms Malignant
Study of Oncological Outcomes of D3 Lymph Node Dissection in Colon Cancer
The purpose of this study is to determine wether D3 lymph node dissection gives superior oncological outcomes compared to standard D2 lymph node dissection in colon cancer
- Trial name
- COLD (NCT03009227)
- Testing
- Colonic resection with D2 lymph node dissection, Colonic resection with D3 lymph node dissection
- Where
- 12 sites in Russia
- Volunteers
- 780 people
- Sponsor
- N.N. Petrov National Medical Research Center of Oncology
Breast Neoplasms
Omitting Completion Axillary Treatment in Sentinel Node Positive Breast Cancer Patients Undergoing a Mastectomy
STUDY AIM To decrease the number of breast cancer patients receiving overtreatment of the axilla, in order to positively influence the axillary morbidity rate and quality of life.
- Trial name
- NCT02112682
- Testing
- Completion axillary treatment
- Where
- 31 sites in Netherlands
- Volunteers
- 52 people
- Sponsor
- Maastricht University Medical Center
Lung Cancer (NSCLC), Lymph Node Dissection
Selective Lymph Node Resection for Invasive Non-small Cell Lung Cancer With the CTR of 0.5-1 and the Diameter of ≤ 2 cm
The study investigated the efficacy and safety of a selective lymph node strategy (no lower mediastinal lymph node dissection for upper lobe tumors and no upper mediastinal lymph node dissection for lower lobe tumors) in patients…
- Trial name
- NCT06634979
- Testing
- Selective lymph node dissection
- Where
- China
- Volunteers
- 684 people
- Sponsor
- Fudan University
Cervical Cancer, Lymph Node Metastasis
Development of an Imaging Prediction Model for Pelvic Lymph Node Metastasis of Cervical Cancer Using Artificial Intelligence Techniques.
This study is a retrospective exploratory trial conducted at a single center, aiming to develop and validate a preoperative lymphatic metastasis model for cervical cancer using artificial intelligence deep learning.
- Conditions
- Cervical Cancer, Lymph Node Metastasis, Artificial Intelligence
- Trial name
- NCT06448897
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Obstetrics & Gynecology Hospital of Fudan University
Colon Cancer
Metastatic Lymph Node Distribution in the Ileum Mesentery of Cecal and Proximal Ascending Colon Cancer
Based on the above considerations, our team maintains that it is currently imperative to conduct a prospective multicenter registry study.
- Trial name
- NCT07149623
- Testing
- Experimental
- Volunteers
- 406 people
- Sponsor
- Peking Union Medical College Hospital
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