Clinical trials: Lymph Node Dissection
Gastrectomy, Laparoscopy
A Clinical Study for Comparison of the Effects Between Gasless Laparoscopy and Conventional Laparoscopy for Distal Gastric Cancer
The aim of this trial is to confirm the non-inferiority of Gasless laparoscopy-assisted distal D2 radical gastrectomy to the conventional laparoscopy-assisted distal D2 radical gastrectomy for the treatment of advanced gastric…
- Trial name
- NCT05495217
- Testing
- Conventional Laparoscopy, Gasless Laparoscopy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xue Yingwei
Lung Neoplasms, Neoplasm Metastasis
Mediastinal Lymph Node Dissection in Conjunction With Pulmonary Metastasectomy From Colorectal Cancer
To study whether or not total mediastinal lymph node dissection in conjunction with pulmonary metastasectomy from colorectal cancer is associated with improved survival compared to pulmonary metastasectomy only.
- Conditions
- Lung Neoplasms, Neoplasm Metastasis, Colorectal Cancer
- Trial name
- NCT03113318
- Testing
- Total mediastinal lymph node dissection and pulmonary metastasectomy, Only pulmonary metastasectomy
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Gastric Cancer (GC), No.4sb
The Possible Range of No.4sb Lymph Node Dissection of Locally Advanced Distal Gastric Cancer
The main purpose of this study is to evaluate the reasonable range of No.4sb lymph node dissection of locally advanced distal gastric cancer.
- Trial name
- Range of 4sb (NCT07183150)
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Breast Cancer, Breast Neoplasms
Augmented-Reality ICG Fluorescence Second-Look for Residual Nodal Disease After Axillary Dissection in Breast Cancer
This study tests whether special imaging goggles can help surgeons find lymph nodes that may be left behind during breast cancer surgery.
- Conditions
- Breast Cancer, Breast Neoplasms, Sentinel Lymph Node, Lymphatic Metastasis
- Trial name
- AR4SLN (NCT07696754)
- Testing
- Augmented-reality ICG fluorescence second-look imaging
- Where
- North Macedonia
- Volunteers
- 30 people
- Sponsor
- Ss. Cyril and Methodius University of Skopje
Gastric Cancer
National Multicenter Cohort Study of Robot-Assisted Gastrectomy Versus Laparoscopy in Gastric Cancer
In recent years there has been a rapid incursion of robotic technology applied to almost all fields of surgery. In gastric cancer, whose mainstay of treatment is still surgical resection, gastrectomy with robotic lymphadenectomy…
- Trial name
- ROBOTAG (NCT06242613)
- Testing
- Robot-Assisted Gastrectomy, Laparoscopic Gastrectomy
- Where
- Spain
- Volunteers
- 400 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Breast Cancer Lymphedema
Does Immediate Lymphatic Reconstruction Decrease the Risk of Lymphedema After Axillary Lymph Node Dissection
The researchers are doing this study to see if having immediate lymphatic reconstruction after axillary lymph node dissection (ALND) can decrease the development of lymphedema, a side effect of ALND.
- Trial name
- NCT04241341
- Testing
- Axillary Lymph Node Dissection with Immediate Lymphatic Reconstruction, Axillary Lymph Node Dissection without Immediate Lymphatic Reconstruction, quality-of-life questionnaires
- Where
- 7 sites in United States
- Volunteers
- 180 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Melanoma
A Phase II Study of Pegylated Interferon Alfa-2b for the Adjuvant Treatment of Melanoma Subjects in Russia (MK-4031-400)
This study will assess the safety of Pegylated Interferon Alfa-2b (PEG-IFN) as an adjuvant treatment for melanoma.
- Trial name
- NCT02155322
- Testing
- Pegylated Interferon Alfa-2b
- Volunteers
- 33 people
- Sponsor
- Merck Sharp & Dohme LLC
Sentinel Lymph Node
Bronchial NIR Image-guided Resection
This is a clinical trial to evaluate the use of peritumoral injection of near-infrared dye indocyanine green to identify lung lesions and sentinel lymph nodes.
- Trial name
- NCT03097575
- Testing
- ICG Intervention, Near Infrared Imaging
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Melanoma
Comparing SLNE With or Without Preoperative Hybrid SPECT/CT in Melanoma
Melanoma has become a growing interdisciplinary problem in public health worldwide. It characteristically disseminates in an orderly progression through lymphatic channels to the regional lymph node and then to more distant…
- Trial name
- NCT03683550
- Testing
- SLNE with preoperative hybrid SPECT/CT, Standard SLNE
- Where
- 13 sites in Germany
- Volunteers
- 836 people
- Sponsor
- University Hospital, Essen
Prostate Cancer
Bilateral Versus Unilateral Lymph Node Dissection in High-Risk Prostate Cancer (BALANCE)
BALANCE is a multicenter, prospective, randomized controlled trial enrolling men with unilateral high-risk localized prostate cancer identified by prostate biopsy, multiparametric MRI, and PSMA PET imaging.
- Trial name
- BALANCE (NCT07580196)
- Testing
- Unilateral Extended Pelvic Lymph Node Dissection, Bilateral Extended Pelvic Lymph Node Dissection
- Where
- 14 sites in Italy
- Volunteers
- 820 people
- Sponsor
- University of Turin, Italy
Breast Cancer
Regional Anesthesia for Modified Radical Mastectomy With Axillary Lymph Node Dissection
local and regional anesthesia have been introduced with the goal of reducing the side effects associated with general anesthesia and IV opioid analgesia.our hypothesis is that ultrasound-guided interscalene brachial plexus block…
- Trial name
- NCT04239716
- Testing
- regional anesthesia
- Where
- Egypt
- Volunteers
- 13 people
- Sponsor
- Tanta University
Breast Cancer Female
Selective Axillary Dissection After Neoadjuvant Chemotherap Yin Patients With Lymphnode-positive Breast Cancer
The aim of this observational study is to collect data regarding the selective axillary dissection tecnique of lymphnode restaging after neoadjuvant chemotherapy in patients with Breast Cancer that is lymphonode positive at the…
- Trial name
- CLYP (NCT07828925)
- Where
- Italy
- Volunteers
- 105 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Esophageal Cancer, Recurrent Laryngeal Nerve
The Value of Near-Infrared Fluorescence Imaging in the Protection of the Recurrent Laryngeal Nerve During Minimally Invasive Esophagectomy
The goal of this clinical trial is to learn whether the application of indocyanine green near-infrared imaging system can accurately locate the recurrent laryngeal nerve (RLN) during lymph node dissection in esophageal cancer…
- Conditions
- Esophageal Cancer, Recurrent Laryngeal Nerve, ICG (Indocyanine Green), Lymph Node Dissection
- Trial name
- NCT07406815
- Testing
- ICG (Indocyanine Green)
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Fujian Medical University Union Hospital
Malignant Melanoma
Suction Drain in Axillary Lymph Node Dissection for Malignant Melanoma
Postoperative complications like seroma formation and wound site infection readily occur following completion axillary lymph node dissection (ALND) for malignant melanoma.
- Trial name
- NCT04648163
- Where
- Austria
- Volunteers
- 118 people
- Sponsor
- Medical University of Graz
Melanoma, Merkel Cell Carcinoma
Videoscopic Versus Open Inguinal Lymphadenectomy for Cancer
Patients with melanoma, some other rare skin cancers, and some cancers of the penis and scrotum can have their cancer spread to the lymph nodes in the upper part of the leg, called the groin.
- Conditions
- Melanoma, Merkel Cell Carcinoma, Squamous Cell Carcinoma, Penile Carcinoma
- Trial name
- NCT01526486
- Testing
- Videoscopic procedure, Open, traditional approach
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Emory University
Right Sided Colon Cancer, Right Colectomy
Right Colectomy for Colon Cancer Database (RCC). Surgical Technique, Route of Access and Quality of the Specimen
Aim of the project is to surveil results after extended lymphadenectomy for right sided colon resection for cancer with different operative techniques. Patients operated for right sided colon cancer will be involved.
- Conditions
- Right Sided Colon Cancer, Right Colectomy, Lymphadenectomy
- Trial name
- RCC (NCT06329102)
- Testing
- Surgical access
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- Haukeland University Hospital
Stage II Breast Cancer, Stage IIIA Breast Cancer
Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy
This randomized phase III trial studies lymph node dissection and radiation therapy to see how well it works compared to radiation therapy alone in treating patients with breast cancer previously treated with chemotherapy and…
- Trial name
- NCT01901094
- Testing
- Axillary Lymph Node Dissection (ALND), Nodal Radiation Therapy, Axillary Radiation Therapy
- Where
- 1,246 sites in United States, Canada and 1 more
- Volunteers
- 2,012 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Carcinoma of the Endometrium, Hysterectomy
Lymphedema After Primary Surgery for Endometrial Cancer
The purposes of this study are to determine the prevalence, size and impact on quality of life of lymphedema of the lower extremities after primary radical surgery with hysterectomy +/- pelvic - and paraaortic lymphadenectomy in…
- Conditions
- Carcinoma of the Endometrium, Hysterectomy, Lymphadenectomy
- Trial name
- LASEC (NCT02115477)
- Testing
- Lymphadenectomy
- Where
- 16 sites in Sweden
- Volunteers
- 262 people
- Sponsor
- Preben Kjolhede, MD, professor
Gynecologic Neoplasms
Safety of Regular Diet as the First Meal in Patients Who Underwent Surgical Treatment for Gynecologic Cancer
The purpose of this study is to determine whether it is safe to give a regular diet as the first postoperative meal in patients who underwent surgical treatment for clinically early-stage gynecologic cancer.
- Trial name
- NCT00328757
- Testing
- Regular diet as the first postoperative meal
- Where
- Thailand
- Volunteers
- 240 people
- Sponsor
- Chiang Mai University
Invasive Breast Cancer, Axillary Metastases
Sentinel Lymph Node After Neoadjuvant Chemotherapy in Breast Carcinoma
Sentinel lymph node dissection (SLND) after NAC, aimed to reduce the rate of unnecessary axillary lymphadenectomy, is not a standard of care in case of patient with previously involved node before NAC because of a too high false…
- Trial name
- GANEA3 (NCT03630913)
- Testing
- Tagged axillary metastatic node
- Where
- 18 sites in France
- Volunteers
- 385 people
- Sponsor
- Institut Cancerologie de l'Ouest