Clinical trials: Lymph Node Excision
Non-small Cell Lung Cancer
The Accuracy of Targeted Lymph Node Dissection of Non-small Cell Lung Cancer Patients According to Predictive Models
Investigators combined the clinical and radiomics characteristics of resectable non-small cell lung cancer patients to construct an accurate model for preoperative prediction of mediastinal lymph node status.
- Trial name
- NCT06768853
- Testing
- Lymph node dissection based on the guidelines, Lymph node dissection based on the model
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhongnan Hospital
Ovarian Cancer
Lymphadenectomy In Ovarian Neoplasms
To assess the efficacy of systematic pelvic and para-aortic lymphadenectomy in patients with advanced ovarian cancer and intra-abdominal complete debulking.
- Trial name
- LION (NCT00712218)
- Testing
- No Lymphadenectomy (LNE), Lymphadenectomy (LNE)
- Where
- 59 sites in Austria, Belgium and 4 more
- Volunteers
- 640 people
- Sponsor
- Philipps University Marburg
Endometrial Cancer, Sentinel Lymph Node
Intraoperative Examination of Sentinel Node in Endometrial Cancer (TRSGO-SLN-003)
More than half of the cases with macrometastatic sentinel lymph node (SLN) have non-SLN metastasis and leaving these nodes in-situ may impair the survival.
- Trial name
- TRSGOSLN003 (NCT04560491)
- Testing
- Intraoperative examination of sentinel node
- Where
- Turkey (Türkiye)
- Volunteers
- 208 people
- Sponsor
- Ankara University
Stomach Neoplasms
Randomized Controlled Trials on Laparoscopic No. 14v LNS Dissection
The purpose of this study is to explore the short-term, long-term and oncological outcomes of laparoscopic No. 14v lymph node dissection in advanced lower third gastric cancer.
- Trial name
- NCT02789891
- Testing
- D2 lymphadenectomy including No. 14v, lymphadenectomy excluding No. 14v
- Volunteers
- 326 people
- Sponsor
- Fujian Medical University
Stomach Neoplasms, Indocyanine Green
Indocyanine Green Tracer Using in Laparoscopic Gastrectomy With Lymph Node Dissection
The purpose of this study is to explore the clinical outcomes of Indocyanine Green Tracer using in laparoscopic gastrectomy with lymph node dissection for gastric adenocarcinoma（cT1-4a, N-/+, M0）.
- Trial name
- ICGTinLG (NCT03050879)
- Testing
- Indocyanine Green Tracer
- Where
- China
- Volunteers
- 266 people
- Sponsor
- Fujian Medical University
Stage IIA-IIIB NSCLC, Selective Mediastinal Lymph Node Sampling
Selective Mediastinal Lymph Node Sampling Versus Systematic medIastinal Lymph Node Dissection After Neoadjuvant Chemoimmunotherapy for Non-small Cell Lung Cancer (SCIENCE Study)
The SCIENCE trial is a multicenter, open-label, randomized, parallel, noninferiority investigator-initiated trial (IIT). This study aims to evaluate the prognostic differences between selective mediastinal lymph node sampling and…
- Conditions
- Stage IIA-IIIB NSCLC, Selective Mediastinal Lymph Node Sampling, Systematic medIastinal Lymph Node Dissection
- Trial name
- NCT07617389
- Testing
- selective mediastinal lymph node sampling, systematic mediastinal lymph node dissection
- Where
- China
- Volunteers
- 358 people
- Sponsor
- Wen-zhao ZHONG
Endometrial Neoplasms, Ovarian Neoplasms
STELLA Trial: Transperitoneal vs. Extraperitoneal Approach for Laparoscopic Staging of Endometrial/Ovarian Cancer
The purpose of this study is to determine whether the extraperitoneal approach is better than the transperitoneal approach for laparoscopic aortic lymphadenectomy for the surgical staging of endometrial or ovarian cancer.
- Trial name
- STELLA (NCT01810874)
- Testing
- Transperitoneal laparoscopic aortic lymphadenectomy, Extraperitoneal laparoscopic aortic lymphadenectomy
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Colorectal Neoplasms Malignant, Lymph Node Excision
Chemoradiotherapy Sequenced Radical Surgery for Colorectal Cancer With PALNM
In left-sided colon and rectal cancer, the occurrence of synchronous para-aortic lymph node metastasis is rare, with the incidence of being approximate 1-2%.
- Conditions
- Colorectal Neoplasms Malignant, Lymph Node Excision, Chemoradiotherapy
- Trial name
- NCT05129774
- Testing
- Radical surgery with PALND, Radical surgery without PALND
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Qilu Hospital of Shandong University
Hidden Blood Loss, Single-site Laparoscopy
A Research on Hidden Blood Loss in Laparoendoscopic Single-site Radical Hysterectomy With Pelvic Lymphadenectomy
The aim of this cross-sectional study is to evaluate the hidden blood loss in patients who undergo laparoendoscopic single-site radical hysterectomy with pelvic lymphadenectomy and identity its risk factors.
- Conditions
- Hidden Blood Loss, Single-site Laparoscopy, Radical Hysterectomy
- Trial name
- NCT03626493
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Esophageal Adenocarcinoma
RAMIE Versus MIE for Resectable Esophageal Cancer, a Randomized Controlled Trial (ROBOT-2 Trial).
BACKGROUND: For patients with esophageal cancer, radical esophagectomy with 2-field lymphadenectomy is the cornerstone of the multimodality treatment with curative intent.
- Trial name
- ROBOT-2 (NCT04306458)
- Testing
- Minimally invasive esophagectomy, daVinci Xi system
- Where
- Germany
- Volunteers
- 218 people
- Sponsor
- University Medical Center Mainz
Gastric Cancer
Curative D2 vs D1 Lymphadenectomy in Operable Gastric Carcinoma
Gastric carcinoma is the second most common cause of cancer-related deaths and its main treatment modality if potentially curable is surgery but the optimal surgical resection is controversial.
- Trial name
- NCT04340440
- Testing
- D1 lymphadenectomy, D2 lymphadenectomy
- Volunteers
- 80 people
- Sponsor
- University of Alexandria
Bladder Cancer
PET/MRI and Biomarkers in Bladder Cancer
Muscle invasive bladder cancer is an aggressive malignancy. Currently the investigators lack accurate imaging technologies in clinical staging and estimation of response to neoadjuvant chemotherapy as well as prognostic…
- Trial name
- ACEBIB (NCT01918592)
- Testing
- MRI/acetate-PET imaging
- Where
- 3 sites in Finland
- Volunteers
- 25 people
- Sponsor
- Turku University Hospital
Breast Cancer, Muscle Strength
Effectiveness of PNF Training for Improving for Muscle Strength, Function, and Pain After Axillary Lymph Node Dissection
Breast cancer is the most common type of cancer affecting women of all ages worldwide. Advanced and comprehensive treatment options have increased survival rate and life expectancy, necessitating a focus on the complications of…
- Trial name
- NCT05288036
- Testing
- Proprioceptive Neuromuscular Rehabilitation group, Progressive Resistance Exercise Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Breast Carcinoma, Breast Cancer
Omission of Axillary Lymph Node Dissection in Case of Tumor Spread to Lymph Nodes in the Armpit in Breast Cancer
SENOMAC-ULTRA enrols patients who are planned for upfront surgery for a breast cancer that has spread to lymph nodes in the armpit, and that have been detected already prior to surgery by imaging, e.g. ultrasonography.
- Conditions
- Breast Carcinoma, Breast Cancer, Breast Surgery
- Trial name
- SENOMAC-ULTRA (NCT06869629)
- Testing
- Targeted axillary dissection, Axillary lymph node dissection
- Where
- 4 sites in Finland, South Korea and 1 more
- Volunteers
- 1,380 people
- Sponsor
- Karolinska Institutet
Rectal Cancer
Safety of Mid and Low Rectal Cancer Surgery Without Dissection of the No.253 Lymph Node (S-M-O-O-T-H)
The goal of this clinical trial is to learn about whether it is safe to omit dissection of the No.253 lymph nodes in mid and low rectal cancer surgery.
- Trial name
- NCT06146946
- Testing
- Dissection of the No.253 lymph node, Omitting the dissection of the No.253 lymph node
- Where
- 8 sites in China
- Volunteers
- 1,384 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Endometrial Carcinoma, Lymphadenectomy
The Clinical Significance of Sentinel Lymph Node Imaging Combined With Imaging Examination in Pelvic and Peritoneal Lymphadenectomy for Endometrial Carcinoma
The aim of this prospective cohort study is to explore the clinical significance of sentinel lymph node imaging combined imaging examination evaluation in pelvic and peritoneal lymphadenectomy for endometrial carcinoma management.
- Trial name
- NCT03877627
- Testing
- Pelvic and Peritoneal Lymphadenectomy
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Uterine Cervical Neoplasms
LESs Surgical Radicality for EaRly Stage Cervical Cancer
This study is an open-label, multicenter, randomized, phase II non-inferiority trial (proof of concept study). Its purpose is to evaluate the safety and efficacy of extrafascial hysterectomy plus pelvic-lymph node dissection…
- Trial name
- LESSER (NCT02613286)
- Testing
- Extrafascial Hysterectomy, Modified radical hysterectomy
- Volunteers
- 40 people
- Sponsor
- Hospital de Câncer de Pernambuco
Oligometastatic Hormone-Sensitive Prostate Cancer, Prostate Adenocarcinoma
Prospective Study on the Role of Radical Prostatectomy in Oligo-metastatic Hormone-sensitive Prostate Cancer in Patients on Androgen Deprivation Therapy
MAZINGA is a prospective, single-group pilot study evaluating disease control after robot-assisted radical prostatectomy with extended pelvic lymph-node dissection in men with oligometastatic hormone-sensitive prostate…
- Trial name
- MAZINGA (NCT07766486)
- Testing
- Robot-Assisted Radical Prostatectomy With Extended Pelvic Lymph-Node Dissection
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Nephrectomy, Prostatectomy
Safety and Performance Assessment of a First Four Arms on Demand Open Robotic Solution for Assisted PN, RN and RP
The purpose of this clinical investigation was to evaluate the safety and performance of the Bitrack System and its corresponding ElectroSurgical Endoscopic (ESE) instruments and Non-ElectroSurgical Endoscopic (NESE) instruments…
- Trial name
- NCT06119568
- Testing
- Robot assisted laparoscopic Radical/simple nephrectomy (RN), Partial nephrectomy (PN) or Radical Prostatectomy (RP).
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Rob Surgical Systems S.L.
Endometrial Neoplasms, Ovarian Neoplasms
STELLA 2 Trial: Transperitoneal vs. Extraperitoneal Approach for Laparoscopic Staging of Endometrial/Ovarian Cancer
The purpose of this study is to determine whether or not there are more complications in the extraperitoneal compared with the transperitoneal approach for laparoscopic aortic lymphadenectomy for the surgical staging of…
- Trial name
- STELLA-2 (NCT02676726)
- Testing
- Extraperitoneal Laparoscopic aortic lymphadenectomy, Transperitoneal Laparoscopic aortic lymphadenectomy
- Where
- Spain
- Volunteers
- 208 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute