Clinical trials: Lymph Node Neoplasm
Bladder Cancer
Checkpoint Inhibitor and Radiation Therapy in Bulky, Node-Positive Bladder Cancer
Clinically node positive (cN+) bladder cancer carries a poor prognosis, especially in patients who are unable to receive or fail to respond to neoadjuvant chemotherapy.
- Trial name
- CIRTiN-BC (NCT04779489)
- Testing
- personalized ultrafractionated stereotactic ablative radiotherapy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Texas Southwestern Medical Center
Thyroid Cancer
The Value of 68Ga-FAPI PET/CT in Preoperative Evaluation of Thyroid Cancer with Lymph Node Metastases
This study aims to investigate the value of 68Ga-FAPI in the preoperative evaluation of thyroid cancer of different pathologic types.
- Trial name
- NCT06730529
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Ruijin Hospital
Breast Cancer
Impact of Osteopathic Manipulative Medicine on Sentinal Lymph Node Biopsy Dye and Tracer Uptake
The goal of this clinical trial is to learn if osteopathic manipulative medicine (OMM) will allow for more uptake of isosulfan blue dye and radiotracers used in sentinal lymph node biopsy (SLNB) compared to massage alone.
- Trial name
- OMM on SLNB (NCT07269860)
- Testing
- OMM prior to SLNB
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Arizona
Lung Cancer
EBUS/Spectrum Analysis
To evaluate the clinical benefit of spectrum analysis of endobronchial ultrasound images of lymph nodes during EBUS TBNA for lymph node staging in patients with lung cancer.
- Trial name
- NCT01972386
- Testing
- Spectrum Image Analysis using a Linear Array Ultrasound Bronchoscope
- Where
- Canada
- Volunteers
- 122 people
- Sponsor
- University Health Network, Toronto
Colon Cancer, Lymph Node Dissection
A Comparative Study of Tumor Specific Mesocolic Excision and Complete Mesocolic Excision for Right Sided Colon Cancer : Asian Multicenter Retrospective Study
The goal of this observational study is to determine the optimal surgical strategy based on oncologic outcomes in patients with stage I-III right-sided colon cancer who underwent curative right hemicolectomy.
- Conditions
- Colon Cancer, Lymph Node Dissection, Laparoscopic Colon Surgery, Robotic Surgical Procedure
- Trial name
- NCT06865586
- Where
- South Korea
- Volunteers
- 3,326 people
- Sponsor
- Asan Medical Center
Cancer
Multicentric Retrospective Review of Extracapsular Lymph Node Involvement After Esophagectomy
It is well known that lymph node metastasis is one of the most important prognostic factors in oesophageal carcinoma. The investigators want to determine the influence of lymph node characteristics, being either intracapsular or…
- Trial name
- ECLNI-MC (NCT01837173)
- Where
- Belgium
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Gasthuisberg
Sentinel Lymph Node, Early Gastric Cancer
Feasibility Study of Sentinel Navigation Surgery After Non-curative Endoscopic Resection
Purpose: To prove the feasibility of sentinel node navigation surgery (SNNS) in early gastric cancer patients with the risk of lymph node metastasis after endoscopic resection and preparation of multicenter phase 3 trial of…
- Trial name
- SENORITA2 (NCT03123042)
- Testing
- Sentinel basin dissection
- Where
- 9 sites in South Korea
- Volunteers
- 243 people
- Sponsor
- National Cancer Center, Korea
Esophageal Squamous Cell Carcinoma
Adjuvant Chemotherapy in Combination With Tislelizumab in Lymph Node-Positive Esophageal Squamous Cell Carcinoma
Esophageal cancer is one of the most common malignancies in China, and esophageal squamous cell carcinoma (ESCC) is the predominant histological type.
- Trial name
- NCT05984342
- Testing
- Tislelizumab
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Affiliated Cancer Hospital of Shantou University Medical College
Cervical Cancer
Analysis of Parametrial Lymph Nodes as Sentinel Nodes in Patients With Cervical Cancer
The goal of this clinical research study is to find out if the parametrial nodes are "sentinel" nodes (the lymph nodes believed to be the greatest risk for the spread of cancer) and if intraoperative lymphatic mapping can…
- Trial name
- NCT00631241
- Testing
- Single Photon Emission Computed Tomography, Intraoperative Lymphatic Mapping
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer, Lymph Node Metastases
Use of Indocyanine Green During Pelvic Lymph Node Dissection in Prostate Cancer.
Standard treatment of local or locally advanced prostate cancer is radical prostatectomy (RRP) surgery. During RRP in certain patients extended lymph node dissection (ELND) is recommended.
- Trial name
- NCT04882618
- Testing
- Indocyanine green
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Breast Cancer
Thoracoscopic Sentinel Lymph Node Biopsy in Patients With Stage I or Stage II Breast Cancer
RATIONALE: Diagnostic procedures, such as thoracoscopic sentinel lymph node biopsy, may help find breast cancer that has spread to lymph nodes between the breasts. It may also help doctors plan the best treatment.
- Trial name
- NCT00450723
- Testing
- Isosulfan blue, Axillary Lymph Node Dissection, Surgery
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Miami
Gastric Neoplasm
A Trial to Evaluate Para-aortic Lymphadenectomy for Gastric Cancer
To evaluate the survival benefit of para-aortic lymphadenectomy in potentially curative gastrectomy
- Trial name
- NCT00149279
- Testing
- Surgery: D2 dissection, Surgery: D2+paraaortic dissection
- Where
- Japan
- Volunteers
- 520 people
- Sponsor
- Japan Clinical Oncology Group
Ovarian Neoplasms
Validation of the Sentinel Lymph Node Technique in Early-stage Ovarian Cancer (SENTOV II)
This clinical trial investigates the sentinel lymph node (SLN) technique as a less invasive alternative to conventional lymphadenectomy in patients with early-stage ovarian cancer.
- Trial name
- SENTOV II (NCT06963268)
- Testing
- Sentinel Node Technique
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Squamous Cell Carcinoma, Nonmelanoma Skin Cancer
Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck
The purpose of this study is to research if a type of biopsy known as sentinel lymph node biopsy (SLNB) can help in determining the rate of tumor deposits that are hard to detect and identify in node-negative cutaneous squamous…
- Conditions
- Squamous Cell Carcinoma, Nonmelanoma Skin Cancer, Cutaneous Squamous Cell Carcinoma
- Trial name
- NCT05108090
- Testing
- sentinel lymph node biopsy (SLNB)
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Indiana University
Melanoma, Skin Cancer
Interferon Alfa With or Without Combination Chemotherapy Plus Interleukin-2 in Treating Patients With Melanoma
RATIONALE: Interferon alfa may interfere with the growth of cancer cells. Interleukin-2 may stimulate a person's white blood cells to kill melanoma cells.
- Trial name
- NCT00002882
- Testing
- Aldesleukin (IL-2), Recombinant Interferon Alfa (IFN-A), Cisplatin
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer
Sentinel Node Biopsy Before and/or After Neoadjuvant Chemotherapy in Breast Cancer
The purpose of this study is to investigate if sentinel lymph node biopsy is a reliable staging tool for breast cancer patients planned for neoadjuvant chemotherapy (=before breast surgery) and if, in that case, it is safe to…
- Trial name
- NCT02031042
- Where
- 20 sites in Sweden
- Volunteers
- 224 people
- Sponsor
- Stockholm South General Hospital
Endometrial Neoplasms
Sentinel Lymph Node Detection in Endometrial Cancer
In endometrial cancer (EC) pelvic and paraaortic lymphadenectomy is performed only in high risk groups (with approximately 20% of patients having lymph node metastases (LNM)) whereas no lymphadenectomy is recommended in low risk…
- Trial name
- NCT02690259
- Testing
- Sentinel node procedure
- Where
- Sweden
- Volunteers
- 257 people
- Sponsor
- Region Skane
Esophageal Cancer
NIR-Guided Sentinel Lymph-Node Mapping for Esophageal Cancer
This research study is a Phase I clinical trial. Phase I clinical trials test the feasibility and safety of an investigational technique or drug.
- Trial name
- NCT01808417
- Testing
- Near Infrared Imaging
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Dana-Farber Cancer Institute
Head Cancer, Neck Cancer
Study Comparing Lymphoseek® vs. Albumin Nanocolloid in Head and Neck, Melanoma and Breast Cancer
Comparison of the concordance of albumin nanocolloid and Lymphoseek® in the detection of lymph nodes of primary and secondary stage drainage by performing two lymphogammagrams
- Conditions
- Head Cancer, Neck Cancer, Melanoma, Breast Cancer
- Trial name
- SENTINELSEEK (NCT04261179)
- Testing
- Lymphoseek, Nanocoll
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Anna Cruceta
HIV Infections, Giant Lymph Node Hyperplasia
Rituximab in the Treatment of HIV Associated Multicentric Castleman Disease Dependent on Chemotherapy
This trial is aimed to study the efficacy of 4 weekly cycles of rituximab in HIV-infected patients with multicentric Castleman disease (giant lymph node hyperplasia) dependent on chemotherapy.
- Trial name
- NCT00127569
- Testing
- Rituximab
- Volunteers
- 25 people
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
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