Clinical trials: Lymphatic Function
Head and Neck Neoplasms, Head and Neck Lymphedema
Response to Intermittent Pneumatic Compression Therapy in Head and Neck Cancer-Related Lymphedema
Assessment of lymphatic structure and function pre- and post- treatment and during recovery in head and neck cancer related lymphedema patients using NIR fluorescence lymphatic imaging: Response to ICD therapy in HNC Patients.
- Conditions
- Head and Neck Neoplasms, Head and Neck Lymphedema, Head and Neck Cancer
- Trial name
- NCT02946021
- Testing
- Head and neck garments for pneumatic compression device, NIRFLI with ICG
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Tactile Medical
Asthma; Eosinophilic
Homeostatic Roles of Eosinophils in Asthma
The HOMEOS study is an exploratory, observational, and monocentric research. It focuses on characterizing the homeostatic roles of eosinophils in severe asthma.
- Trial name
- HOMEOS (NCT06676397)
- Testing
- Blood Punction
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Menopause, Cognitive Deficits, Mild
Effect of Time-restricted Eating on Cognitive Function and Other Biopsychosocial Factors in Menopausal Women Undertaking a 12-week Exercise Programme
The goal of this quasi-experimental study is to test effect of time-restricted eating on cognitive function and other biopsychosocial factors in menopausal women undertaking a 12-week exercise programme.
- Trial name
- NCT06138015
- Testing
- Exercise and Time-Restricted Eating, Exercise only
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Myeloid Leukemia, Lymphoblastic Leukemia
Efficacy and Safety of a Donor Lymphocyte Preparation Depleted of Functional Host Alloreactive T-cells (ATIR) in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical Donor
The purpose of this study is to determine whether the administration of a donor lymphocyte preparation depleted of functional host alloreactive T-cells (ATIR) after a T-cell depleted stem cell transplant from a related…
- Conditions
- Myeloid Leukemia, Lymphoblastic Leukemia, Lymphoma, Multiple Myeloma
- Trial name
- NCT00967343
- Testing
- Donor lymphocyte preparation depleted of host functional alloreactive T-cells
- Where
- 15 sites in United States, Belgium and 5 more
- Volunteers
- 40 people
- Sponsor
- Kiadis Pharma
Breast Cancer, Lymphedema
Morbidity Following the Diagnosis and Treatment of Patients With Breast Cancer
This study will examine the frequency and severity of problems in women with breast cancer during the first year after initial medical treatment, including: Physical impairments, such as loss of strength or flexibility, increased…
- Conditions
- Breast Cancer, Lymphedema, Physical Therapy, Shoulder
- Trial name
- NCT00027105
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Poor Graft Function, Aplastic Anemia Idiopathic
REscuing Bone Marrow Function in Patients with AplaStic AnaEmia and Bone Marrow FaiLure Post AllogEneiC Transplantation 2
Allogeneic stem cell transplantation involves the transplanting of donor blood stem cells into a recipient, this is performed mainly for the treatment of blood cancers.
- Trial name
- RESELECT2 (NCT06607367)
- Testing
- Ruxolitinib (JAKAVI®), Eltrombopag (Revolade®)
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Melbourne Health
Anticoagulants and Bleeding Disorders, Surgery
Residual Anti-Xa Activity After Last Treatment Dose of Enoxaparin
The main objective of this study is to determine the time interval following the last treatment dose of enoxaparin at which the amount of anti-Xa level activity is reliably less than 0.2 international unit per milliliter (IU/mL)…
- Conditions
- Anticoagulants and Bleeding Disorders, Surgery, Regional Anesthesia Morbidity
- Trial name
- NCT03296033
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Wake Forest University Health Sciences
Univentricular Heart, Congenital Heart Disease
Lymphatic Function in Patients With Fontan Circulation: Effect of Physical Training
Background: The Fontan operation has been used to treat complex cardiac anomalies with a single-functioning ventricle. A study performed by Instituto do Coracão-Hospital das Clínicas-Universidade de Sao Paulo…
- Conditions
- Univentricular Heart, Congenital Heart Disease, Lymphatic Abnormalities, Functional Capacity
- Trial name
- NCT05934578
- Testing
- Exercise training
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Hodgkin Lymphoma, Hodgkin Disease
Prevention of Ovarian Function Damage by a GnRH Analogue During Chemotherapy in Hodgkin Lymphoma Patients
Chemotherapy as one of the basic modalities of oncology treatment often leaves permanent implications and among the most common is infertility as a result of irreversible gonadal damage.
- Trial name
- OVARONKO (NCT01764230)
- Testing
- triptorelin
- Where
- Czechia
- Volunteers
- 72 people
- Sponsor
- Masaryk University
Lipedema, Overweight and Obesity
Ketogenic Diet in Women With Lipedema
Lipedema is a chronic fat tissue disorder that usually affects the lower limbs, excluding the feet. Clinical symptoms of lipedema include a noticeable disproportion between the upper and lower body, a tendency to easy bruising…
- Trial name
- NCT07530341
- Testing
- Low carbohydrate high fat (ketogenic) diet with anti-inflammatory properties
- Where
- Poland
- Volunteers
- 121 people
- Sponsor
- Wroclaw Medical University
Leukemia, Acute, Brain Neoplasms
Physical Activity and Quality of Life in Childhood Cancersurvivors- a Long-term Follow-up
The project intends to study physical functional capacity and degree of physical activity health related quality of life and fatigue.
- Conditions
- Leukemia, Acute, Brain Neoplasms, Physical Fitness, Quality of Life
- Trial name
- NCT07046481
- Testing
- Physical activity
- Sponsor
- Region Skane
Hodgkins Lymphoma
Protection of Ovarian Function in Female Patients With Hodgkin Lymphoma
This study is designed to test the the protective capacity of Goserelin compared with oral contraceptive
- Trial name
- PROFE (NCT01014507)
- Testing
- 8 cycles BEACOPPesc plus oral contraceptive, 8 cycles BEACOPPesc plus Goserelin
- Volunteers
- 60 people
- Sponsor
- University of Cologne
Quality of Life, Graft-vs-Host Disease
Cognitive Function and Patient-Reported Quality of Life Outcomes Investigation in Patients Taking Vorinostat
Psychological well-being and cognitive function will be measured in patients enrolled on the primary study, NCT01790568, a phase 2 trial of vorinostat plus tacrolimus and methotrexate to prevent graft versus host disease…
- Trial name
- NCT02409134
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Sung Choi, M.D.
Pulmonary Langerhans Cell Histiocytosis
Evaluation of Outcome of Adult Pulmonary Langerhans Cell Histiocytosis Based on Lung HRCT and Lung Function
this is a multicenter retrospective study on patients with pulmonary LCH who were sequentially evaluated by concomitant lung HRCT and lung function testing.
- Trial name
- HLP (NCT01651507)
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Multiple Myeloma, Impaired Renal Function
Pharmacokinetics of Lenalidomide (Revlimid®) in Patients With Multiple Myeloma and Impaired Renal Function
The purpose of this study is to determine the pharmacokinetic profile of Revlimid® in patients presenting with Multiple Myeloma and impaired renal function, the safety of Revlimid® in the enrolled patients population.
- Trial name
- NCT00779922
- Testing
- lenalidomide
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Poitiers University Hospital
Acute Lymphoblastic Leukemia
Effects of Core Stabilization Exercises in Children With Acute Lymphoblastic Leukemia
The goal of this clinical trial is to investigate the effects of core stabilization exercises applied in addition to the conventional exercise program on physical function, functional muscle strength, functional exercise…
- Trial name
- NCT06794762
- Testing
- Conventional exercises, Core stabilization exercises in addition to conventional exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Karamanoğlu Mehmetbey University
Surgery, Obesity Associated Disorder
Bariatric Surgery on obesity-and Diabetes-associated Abnormalities of Hemostasis, Inflammation and Vascular Function.
The goal of this prospective cohort study is to examine circulating biomarkers before and after weight loss in patients with obesity, with or without concomitant diabetes, undergoing bariatric surgery.
- Conditions
- Surgery, Obesity Associated Disorder, Coagulation Disorder, Diabetes Complications
- Trial name
- FIBRINO (NCT06071559)
- Testing
- Laparoscopic Roux-en-y gastric bypass
- Volunteers
- 61 people
- Sponsor
- Ersta Diakoni
Heart; Surgery, Heart, Functional Disturbance as Result, Pediatric ALL
Oblique Versus Transverse Orientation Approach for Internal Jugular Venous Cannulation in Pediatrics
this study aimed to compare oblique versus transverse orientation approach in jugular venous cannulation in term of cannulation success in pediatric heart surgery patients
- Trial name
- NCT05656937
- Testing
- internal jugular venous cannulation
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Coagulation Disorder, Coagulation Function
Effects of Lipid Emulsions on Coagulation
The goal of this observational study is to learn how intravenous lipid emulsions may affect blood clotting function in hospitalized patients.
- Trial name
- NCT07470385
- Testing
- Lipid Emulsion
- Where
- China
- Volunteers
- 6,259 people
- Sponsor
- Mimi Tang, PhD
Preeclampsia, Hypertension
Collection of Samples From Pregnant Women for the Evaluation of Preeclampsia (Pre-E) Biomarkers
Preeclampsia (Pre-E) is a hypertensive disease of pregnancy with multi-system involvement that usually occurs in the second half of pregnancy. Pre-E occurs in 5% to 7% of U.S. pregnancies, and is the third-leading cause of U.S.
- Conditions
- Preeclampsia, Hypertension, Proteinuria, Thrombocytopenia
- Trial name
- NCT02780414
- Where
- 20 sites in United States
- Volunteers
- 1,730 people
- Sponsor
- Progenity, Inc.