Clinical trials: Lymphatic Obstruction
Anesthesia, Anesthesia, Local
Caudal Block Versus Dorsal Penile Nerve Block Plus Ring Block for Pain Management of Different Surgical Techniques of Circumcision in Infants and Children
Circumcision is one of the most commonly performed operations in the pediatric population and is a painful procedure. Circumcision is performed with two popular techniques, Plastibell and conventional dissection method (CDM).
- Conditions
- Anesthesia, Anesthesia, Local, Analgesia, Pediatric ALL
- Trial name
- NCT05233683
- Testing
- Caudal block, Dorsal penile nerve block plus ring block, Circumcision with Plastibell
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Saud University
Hip Fractures, Anticoagulants and Bleeding Disorders
Caudal Block & Hip Fracture Surgery in Anticoagulated Patient
Hip fractures are common in elderly patients, and require surgery. Many elderly patients take anticoagulants for vasculopathy treatment.
- Trial name
- NCT05946863
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Salem Anaesthesia Pain Clinic
Sickle Cell Disease, Sickle Cell Anemia
Microvascular Blood Flow in Sickle Cell Anemia
Sickle cell disease (SCD) is an inherited blood disorder that causes the red blood cells to change their shape from a round shape to a half-moon/crescent or sickled shape.
- Trial name
- NCT01566890
- Testing
- regadenoson infusion with contrast-enhanced ultrasound, contrast-enhanced ultrasound
- Where
- 2 sites in United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Versiti Blood Health
Determination of the Occlusion Pressure in Lymphatic Vessels
Determining Occlusion Pressure in Lymphatic Vessels
The lymphatic system is one of the keystones of fluid homeostasis in the interstitium. In analogy with the arterial systolic pressure, the lymphatic systolic pressure can give us information about the functioning of the…
- Trial name
- Occlusion (NCT02359578)
- Testing
- Indocyanine Green
- Where
- Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Anemia, Coronary Disease
PBM as Strategy to CABG Anemic Patients Bypass Graft (CABG)
Anemia poses risks during coronary artery bypass grafting (CABG), increasing complications and mortality rates. Blood transfusions in cardiac surgery have negative outcomes, prompting the use of erythropoietin in Patient Blood…
- Conditions
- Anemia, Coronary Disease, Coronary Artery Disease, Coronary Stenosis
- Trial name
- NCT06542393
- Testing
- Erythropoietin, blood transfusion
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Anesthesia, Local, Ophthalmopathy
Comparison Between Peribulbar And Sub-tenon Blocks on Oculocardiac Reflex (OCR) During Pediatric Strabismus Surgery
The aim of this study is to compare between peribulbar block and subtenon block as an adjunct to general anesthesia in children undergoing strabismus surgery on oculocardiac reflex (OCR), post-operative analgesia and…
- Conditions
- Anesthesia, Local, Ophthalmopathy, Strabismus, Pediatric ALL
- Trial name
- NCT06293586
- Testing
- peribulbar block, sub-tenon block, Paracetamol
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cairo University
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Senile Purpura, Bateman's Purpura
Broad Band Light for the Treatment and Prevention of Senile Purpura
There will be five subjects over the age of 65, each with at least one ecchymotic lesion on each arm measuring at least one cm, and five control subjects under the age of 35, both who will be randomized to undergo 4 Sciton Broad…
- Trial name
- NCT03690375
- Testing
- Broad Band Light (BBL)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Siperstein Dermatology
Lymphatic Obstruction
18F-FTHA IMAGING OF THE INTESTINAL AND CENTRAL LYMPHATIC SYSTEM
The project will be performed over a period of approximately two years. In the first year the [18F]FTHA tracer will be developed, optimized, and tested on normal volunteers.
- Trial name
- FTHA (NCT07645573)
- Testing
- [18F]FTHA PET/CT scan
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Mastectomy; Lymphedema, Chronic Pain
Erector Spinae Block Versus Paravertebral Block on Chronic Pain After Mastectomy
The goal of this clinical trial is to learn if the erector spinae block can reduce the incidence of chronic pain compared to the paravertebral block in adult patients undergoing total mastectomy.
- Conditions
- Mastectomy; Lymphedema, Chronic Pain, Regional Anesthesia Morbidity, Opioid Use
- Trial name
- NCT07561411
- Testing
- Paravertebral block, Erector Spinae block
- Where
- Lebanon
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Mastectomy; Lymphedema, Anesthesia, Local
Ultrasound-guided Paravertebral Block Versus Mid-point Transverse Process Pleura Block in Mastectomy Surgery
This study was performed to analyze the postoperative analgesic effects of the paravertebral block (PVB) and Mid-Point Transverse Process Pleura (MTP) block after a unilateral mastectomy surgery.
- Conditions
- Mastectomy; Lymphedema, Anesthesia, Local, Surgery
- Trial name
- NCT05332028
- Testing
- bupivacaine, 22 gauge 100 mm needle, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Chemotherapy-Induced Neutropenia
Study to Evaluate the Safety, Tolerability and PK of EC-18 After Oral Administration in Healthy Volunteers
This study is a Dose block-randomized, Double-blind, Placebo-controlled, Single and Multiple Ascending Dose Escalation, Phase I clinical trial to assess the safety, tolerability and pharmacokinetics of single-dose and…
- Trial name
- NCT02532712
- Testing
- EC-18
- Where
- South Korea
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Enzychem Lifesciences Corporation
Moderate or Severe Aortic Stenosis
Sparrow App Guided Evaluation (SAGE) Vanguard Trial for Aortic Stenosis in Adults Aged Seventy and Older
The purpose of this research is to look at an approved intervention (Stethophone application) to obtain additional information about improving detection of moderate or severe aortic stenosis when compared with usual standard of…
- Trial name
- SAGE-AS (NCT07828730)
- Testing
- Stethophone
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Lymphatic Function
Lymphatic Occlusion Pressure in Lower Limb
The lymphatic system is one of the keystones of fluid homeostasis in the interstitium. In analogy with the arterial systolic pressure, the lymphatic pressure can give us information about the functioning of the cardiovascular…
- Trial name
- NCT02405559
- Testing
- Indocyanine Green
- Where
- Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre