Clinical trials: Lymphedema, Breast Cancer
Lymphedema, Breast Cancer
Early Detection and Intervention for Mild and Moderate Lymphedema in Patients Treated for Breast Cancer
Women who have been treated for breast cancer may be at risk for lymphedema or arm swelling. Currently, there are no clear treatment guidelines for lymphedema.
- Trial name
- NCT00959985
- Testing
- Compression Sleeve, Short-Stretch Compression Bandage
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Massachusetts General Hospital
Lymphedema, Breast Cancer
Arm Circumference Measurement With or Without Bioimpedance Spectroscopy in Finding Lymphedema Early in Patients With Stage I-III Breast Cancer
This randomized pilot clinical trial studies arm circumference measurement with or without bioimpedance spectroscopy in finding extra lymph node fluid build up in the arm (lymphedema) early in patients with stage I-III breast…
- Trial name
- NCT03648983
- Testing
- arm circumference measurement, Bioimpedance spectroscopy
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Albert Einstein College of Medicine
Breast Cancer Related Lymphedema
A Study Evaluating FT-SW in Unilateral Breast Cancer-Related Lymphedema Patients
The objective of the study is to demonstrate equivalency in treatment effect, as determined by objective measurements, between the modified therapy cycle software and the FDA-cleared Flexitouch therapy cycle software.
- Trial name
- NCT04073823
- Testing
- Flexitouch Plus, Flexitouch Plus FT with software modification
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Tactile Medical
Lymphedema, Breast Cancer
Lymphedema Prophylaxis in Breast Cancer Survivors Who Show Early Evidence of High-risk Status
To compare the effectiveness of usual treatments for lymphedema [massage and elastic compression sleeve, instituted at-risk and before the development of swelling (lymphedema)], compared to the use of a newly-marketed device, the…
- Trial name
- NCT00383500
- Testing
- Flexitouch, Class 1 compression garment
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Stanford University
Breast Cancer, Lymphedema
LLLT Combined With CDT in Breast Cancer-Related Lymphedema
This study aims to explore the effects of Low Level Laser Therapy (LLLT) on breast cancer-related lymphedema when utilized in conjunction with Complex Decongestive Therapy (CDT) when compared to CDT treatment alone.
- Trial name
- NCT01351376
- Testing
- Low Level Laser Therapy, Low Level Laser
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- NYU Langone Health
Arm Lymphedema, Truncal Lymphedema
Home-based Compression Therapy for Arm and Truncal Lymphedema in Breast Cancer
No studies have tested the potential benefit of the Flexitouch® truncal/chest garments on reducing truncal lymphedema in breast cancer survivors (BCS) or the theoretical added benefit of applying truncal/chest pneumatic…
- Conditions
- Arm Lymphedema, Truncal Lymphedema, Breast Cancer
- Trial name
- NCT00880022
- Testing
- Flexitouch System
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Vanderbilt University
Lymphedema, Surgery
Intraoperative Evaluation of Axillary Lymphatics
This study will assess the feasibility of using the OnLume Imaging System for fluorescence-guided surgery along with indocyanine green (ICG) dye in the operating room for the axillary reverse mapping (ARM) procedure in women with…
- Conditions
- Lymphedema, Surgery, Breast Cancer
- Trial name
- NCT05094102
- Testing
- OnLume Imaging System, Indocyanine green
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Wisconsin, Madison
Lymphedema, Secondary, Lymphedema of Upper Limb
Treatment of Breast Cancer-related Lymphedema With a Negative Pressure Device
This study will be a 4 to 6 week randomized, controlled, assessor blinded, trial comparing a negative pressure massage device (intervention group), to the standard manual lymph drainage massage (control group), in breast cancer…
- Trial name
- NCT03252145
- Testing
- PhysioTouch, Manual Lymph Drainage (MLD)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of California, San Francisco
Breast Cancer With Chronic Lymphedema
Acupuncture for Chronic Lymphedema
This study is being done because women have arm swelling for more than 6 months despite wrapping and other treatments. This swelling is called lymphedema. It is the back up of lymph system fluid that causes swelling in the arm.
- Trial name
- NCT01706081
- Testing
- Acupuncture, Wait-list
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer, Upper Extremity Lymphedema
Immunotherapy for the Treatment of Breast Cancer Related Upper Extremity Lymphedema (BCRL)
The purpose of this study is to assess the efficacy of QBX258, a compound developed by Novartis Corporation composed of two antibodies, in reducing arm volume excess in women with stage I-II breast cancer related lymphedema.
- Trial name
- NCT02494206
- Testing
- QBX258
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer, Head and Neck Cancer
Using Traditional Acupuncture in the Management of Cancer Treatment Related Lymphoedema
RATIONALE: Acupuncture and moxibustion may improve well-being and quality of life in patients with lymphedema caused by breast cancer or head, neck, and throat cancer.
- Conditions
- Breast Cancer, Head and Neck Cancer, Lymphedema
- Trial name
- AMWELL-SL (NCT00828516)
- Testing
- Acupuncture and moxibustion
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- East and North Hertfordshire NHS Trust
Breast Cancer Related Lymphedema, Covid19
Patient Experiences With the COVID-19 Vaccination After Breast Cancer Treatment
This study aims to elicit patient experiences, choices, and side effects associated with the COVID-19 vaccine after breast cancer surgery.
- Trial name
- LymphVAX (NCT04872738)
- Testing
- Survey
- Where
- United States
- Volunteers
- 714 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer
Axillary Lymph Node Preservation Surgery in Reducing Lymphedema in Patients With Breast Cancer
This pilot phase I and randomized phase II trial studies the best way to perform axillary lymph node preservation surgery and to see how well it works in preventing lymphedema in patients with breast cancer.
- Trial name
- NCT00932035
- Testing
- axillary lymph node dissection, isosulfan blue based lymphatic mapping, quality-of-life assessment
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- City of Hope Medical Center
Lymphedema, Edema
Prospective Evaluation of a Surgical Solution for Breast Cancer-Associated Lymphedema
To investigate whether addition of the Biobridge scaffold to the standard surgery for vascularized lymph node transfer will improve the outcome of surgical treatment in lymphedema of the upper arm.
- Trial name
- Biobridge (NCT02734979)
- Testing
- Biobridge and lymph node transfer
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stanford University
Lymphedema
Low Level Laser Treatment and Breast Cancer Related Lymphedema
Manual Lymphatic Drainage (massage therapy) with compression (wearing a tight sleeve on the arm) is the current standard of treatment for breast cancer related lymphedema (arm swelling).
- Trial name
- NCT00852930
- Testing
- laser and MLD combined, laser alone, manual lymphatic drainage
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Vanderbilt University
Breast Neoplasm, Lymphedema
Effectiveness of Fluoroscopy-guided MLD for Treatment of BCRL
The main scientific objective of this multicentric double-blinded randomised controlled trial entails examining the effectiveness of fluoroscopy-guided MLD versus traditional MLD versus placebo MLD, applied as part of the…
- Trial name
- EFforT-BCRL (NCT02609724)
- Testing
- Information, Skin care, Compression therapy
- Where
- 3 sites in Belgium
- Volunteers
- 194 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Lymphedema, Recurrent Breast Cancer
Sentinel and/or Axillary Lymph Node Biopsy With or Without Axillary Reverse Mapping in Reducing Incidence and Severity of Arm Lymphedema in Stage 0-2 Patients.
Lymph node biopsy followed by axillary reverse mapping may reduce the incidence and severity of arm lymphedema. This randomized phase II trial is studying how well sentinel and/or axillary lymph node biopsy with or without…
- Conditions
- Lymphedema, Recurrent Breast Cancer, Stage IA Breast Cancer, Stage IB Breast Cancer
- Trial name
- NCT01276054
- Testing
- technetium Tc 99m sulfur colloid, methylene blue, indocyanine green solution
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Southern California
Breast Cancer
Evaluation of BIS for Quantification of Lymphedema
The purpose of this study is to determine whether measuring the fluid in your arms using Bioimpedance Spectroscopy is as effective at detecting and monitoring lymphedema as measurements with the Perometer.
- Trial name
- NCT01544335
- Testing
- Bioimpedance Spectroscopy
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer Lymphedema, Compression Bandages
Effectiveness of Taping on Anastomotic Regions in Patients With Breast Cancer-Related Lymphoedema
One of the most common conservative treatments of lymphoedema is Complex Decongestive Physiotherapy (CDP). The bandage is one of the most important components of the treatment process.
- Conditions
- Breast Cancer Lymphedema, Compression Bandages, Manual Lymphatic Drainage
- Trial name
- NCT03765996
- Testing
- Decongestive Physiotherapy, Decongestive Physiotherapy plus taping
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Dokuz Eylul University
Breast Cancer Lymphedema
Study Evaluating Flexitouch Plus With Connectivity on Compliance in 30 Patients With Breast Cancer-Related Lymphedema.
The objective of this study is to demonstrate the feasibility of using the Flexitouch Plus with Cellular Connectivity (FT-CC) to monitor device use data to determine if reminders to patients impact compliance, and to identify the…
- Trial name
- NCT04432727
- Testing
- Flexitouch Plus with Cellular Connectivity (FT-CC)
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- Tactile Medical