Clinical trials: Lymphedema, Breast Cancer
Lymphedema, Breast Cancer
The LYMPH Trial - Microsurgical Versus Conservative Treatment of Chronic Breast Cancer Associated Lymphedema
The aim of this study is to test whether lymphatic surgery provides better QoL (assessed with the Lymph-ICF-UL, (Lymphedema Functioning Disability and health questionnaire for upper limb lymphedema)) 15 months after randomization…
- Trial name
- LYMPH (NCT05890677)
- Testing
- Surgical Intervention, Conservative Complex Physical Decongestion Therapy
- Where
- 36 sites in United States, Austria and 13 more
- Volunteers
- 280 people
- Sponsor
- University Hospital, Basel, Switzerland
Breast Carcinoma, Lymphedema
Remotivation Process for Improving Adherence to Lymphedema Treatment Programs in Patients With Breast Cancer-Related Lymphedema
This trial studies how well the Remotivation Process in an occupational therapy program works in improving adherence to lymphedema treatment programs in patients with breast cancer-related lymphedema.
- Trial name
- NCT04465253
- Testing
- Best Practice, Motivational Interviewing, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- City of Hope Medical Center
Lymphedema, Secondary Lymphedema
Efficacy of Complete Decongestive Therapy for Limb Lymphedema: Response Profile and Predictive Modeling
Background: Complete decongestive therapy (CDT) is the standard treatment for lymphedema, but response varies by localization and laterality.
- Conditions
- Lymphedema, Secondary Lymphedema, Breast Cancer-Related Lymphedema, Upper Extremity Lymphedema
- Trial name
- LYMPH-PROG (NCT07878598)
- Testing
- Intensive phase of Complete Decongestive Therapy
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- Ryazan State Medical University
Breast Cancer
Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery
This trial is to investigate if in patients with clinically node positive breast cancer undergoing upfront surgery, treatment with TAS and ART is superior to ALND in terms of arm-related Quality of Life (QoL) and occurrence of…
- Trial name
- OPBC-10/ NOAX (NCT07140172)
- Testing
- Axillary lymph node dissection (ALND), Axillary radiotherapy (ART)
- Where
- 55 sites in United States, Austria and 9 more
- Volunteers
- 1,060 people
- Sponsor
- University Hospital, Basel, Switzerland
Breast Neoplasms, Radiotherapy
Hypofractionated LocoRegional Radiotherapy in Breast Cancer
The primary objective of this study is to determine if hypofractionated RT delivered over 1 week to the breast or chest wall and regional nodes (26Gy in 5 daily fractions) following BCS or mastectomy, is non-inferior to…
- Conditions
- Breast Neoplasms, Radiotherapy, Lymphedema
- Trial name
- RHEAL (NCT04228991)
- Testing
- Locoregional radiation treatment - Conventional fractionation, Locoregional radiation treatment - Hypofractionation
- Where
- 20 sites in Canada
- Volunteers
- 588 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Lymphedema, Breast Cancer, Mastectomy Related Lymphedema
Complete Decongestive Therapy Versus Non-pneumatic Compression Therapy in Post Mastectomy Lymphedema
The aim of the study is to compare the effectiveness of Complete Decongestive Therapy and Non-Pneumatic Compression Therapy, both combined with routine physical therapy, in reducing pain and edema volume, improving range of…
- Conditions
- Lymphedema, Breast Cancer, Mastectomy Related Lymphedema, Post Mastectomy Lymphedema
- Trial name
- CDT (NCT07217288)
- Testing
- Non Pneumatic compression device, Complete Decongestive therapy
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Breast Cancer Lymphedema
Radial Shock Wave Treatment Alongside Decongestive Care for Arm Swelling After Breast Cancer
Arm swelling can persist after breast cancer treatment and may interfere with comfort, movement, and everyday activities. Decongestive care combines several approaches to manage this swelling.
- Trial name
- NCT07862296
- Testing
- Complex decongestive therapy, Radial extracorporeal shock wave therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Selcuk University
Breast Cancer Related Lymphedema
EFFECT OF ESWT ON BREAST-CANCER RELATED LYMPHEDEMA
The aim of this study is to evaluate the effectiveness of extracorporeal shock wave therapy (ESWT) combined with complete decongestive therapy (CDT) compared with CDT alone in patients with breast cancer-related lymphedema.
- Trial name
- NCT07854262
- Testing
- Complete Decongestive Therapy, Extracorporeal Shock Wave Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ankara City Hospital Bilkent
Lymphedema, Inflammatory Breast Cancer (IBC)
Prediction Of Lymphedema In Patients With Inflammatory BreastCancer Using Preoperative Bioimpedance Measurements
To find out whether the BIA test can help identify participants with IBC who are at risk for developing lymphedema.
- Conditions
- Lymphedema, Inflammatory Breast Cancer (IBC), Preoperative, Bioimpedance Measurement
- Trial name
- NCT07855627
- Testing
- Neoadjuvant therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Neoplasms, Lymphedema Due to Radiation
ICG Lymphography Changes Before and After Radiotherapy in Breast Cancer Patients
The goal of this observational study is to learn how the lymphatic system changes before and after radiotherapy in female patients with breast cancer.
- Trial name
- ICG_prepostRT (NCT07297927)
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Inah Kim
Post Mastectomy Lymphedema
Effect of Resisted Deep Breathing and Myofascial Release in Postmastectomy
This study aims to determine the combined effect of resisted deep breathing and Myofascial release on pain, respiratory efficiency, chest mobility and lymph edema in Postmastectomy.
- Trial name
- NCT07576270
- Testing
- Resisted Deep Breathing, Myofascial release
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Postmastectomy Lymphedema
Can Deep Fascial Thickness Predict Treatment Response in Patients With Postmastectomy Lymphedema? An Ultrasonographic Approach
Research and Literature Summary / References (The research summary must not exceed 250 words and must be written in a clear, easily understandable form.) Lymphedema is a chronic and progressive disease that develops as a result…
- Trial name
- NCT07810036
- Testing
- manual lymphatic drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Breast Cancer Lymphedema
Effect of the Axillary Lymphatic /Vein Reflux Ratio on Postoperative Upper Limb Edema and Dysfunction in Breast Cancer
The purpose of this study is to compare the difference in the incidence of upper limb edema and dysfunction between the Preponderant lymphatic reflux group (high ratio of axillary lymphatic reflux to axillary vein reflux) and the…
- Trial name
- PLEDGE-R (NCT05246592)
- Testing
- Branches Sparing, None Branches Sparing
- Where
- 3 sites in China
- Volunteers
- 258 people
- Sponsor
- Xiangyun Zong
Breast Cancer
A Study Evaluating the Feasibility and Compliance of Manual Lymphatic Drainage Comparing Indocyanine-Green (ICG) Guided vs. Traditional Guided in Patients Undergoing Axillary Node Dissection for the Treatment of Breast Cancer
Breast cancer is estimated to affect approximately 300,000 women in the US in 2023. Studies demonstrate that 1 in 5 will develop breast cancer related lymphedema secondary to the treatments that they receive.
- Trial name
- NCT06327490
- Testing
- ICG-guided manual lymphatic drainage, Traditional manual lymphatic drainage, Indocyanine green
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Breast Cancer-Related Lymphedema, Lymphedema
Effectiveness of a Tele-Rehabilitation-Based Exercise and Self-Lymphatic Drainage Program Supported by Self-Management for Breast Cancer-Related Lymphedema
A total of 64 women, aged between 20 and 65 years, diagnosed with stage I or II breast cancer-related lymphedema and not meeting the exclusion criteria, who registered at the outpatient clinics of the Department of Physical…
- Trial name
- NCT07794904
- Testing
- Tele-rehabilitation-Based Exercise and Self-Lymphatic Drainage Program, Home-Based Exercise and Self-Lymphatic Drainage Program
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istanbul University
Breast Cancer (Locally Advanced or Metastatic), Lymphedema Arm
The Effect of Self-Management Interventions Among Patients With Breast Cancer Related-Lymphedema
To manage lymphedema, it's important to be aware of symptoms and risk factors, evaluate the afflicted extremity, prevent infections, care for the skin, protect the extremity from trauma, maintain a healthy weight, and exercise…
- Trial name
- (BCRL) (NCT07803549)
- Testing
- Self-management Interventions
- Where
- Jordan
- Volunteers
- 100 people
- Sponsor
- Al-Zaytoonah University of Jordan
Secondary Lymphedema
mRNA Therapy to Restore Lymphatic Flow in Secondary Lymphedema
Lymphedema is a common complication of breast cancer treatment, affecting approximately a quarter of patients. Those affected can have an uncomfortable, unsightly and sometimes functionally impaired limb prone to episodes of…
- Trial name
- LymphARN (NCT07793656)
- Testing
- APERNAVEC
- Where
- France
- Volunteers
- 9 people
- Sponsor
- University Hospital, Toulouse
Axillary Web Syndrome, Breast Cancer
Axillary Web Syndrome After Breast Cancer Surgery: Incidence, Risk Factors, and Functional Outcomes
Axillary web syndrome (AWS), sometimes called "cording," is a condition that can develop after breast cancer surgery in which the lymph nodes under the arm are removed or sampled.
- Conditions
- Axillary Web Syndrome, Breast Cancer, Breast Cancer Lymphedema, Postoperative Complications
- Trial name
- NCT07780240
- Testing
- Axillary surgery (sentinel lymph node biopsy or axillary lymph node dissection)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Antalya City Hospital
Breast Cancer, Breast Lymphedema
Efficacy of Kinesio Taping Versus Compression Therapy on Breast Lymphedema Induced by Radiotherapy After Breast-Conserving Surgery
Breast cancer patients often develop breast lymphedema after breast-conserving surgery and radiotherapy, causing swelling, pain, and heaviness that affect quality of life.
- Trial name
- NCT07767305
- Testing
- Routine Care, Kinesio Taping, Compression Therapy
- Where
- China
- Volunteers
- 99 people
- Sponsor
- Tangshan People's Hospital
Lymphedema, Breast Cancer, Lymphedema
LYMPHA Procedure for the Prevention of Lymphedema After Axillary Lymphadenectomy
Lymphedema is a chronic, progressive, and debilitating condition that occurs with disruption or obstruction of the lymphatic system, which commonly occurs a result of breast cancer therapy.
- Trial name
- NCT05366699
- Testing
- axillary lymphadenectomy with immediate lymphatic reconstruction (LYMPHA), Axillary lymphadenetomy alone, axillary lymphadenectomy with soft tissue reinforcement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University